Cover image for Vol. 32 Issue 6

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Navin C. Nanda

Impact Factor: 1.254

ISI Journal Citation Reports © Ranking: 2014: 89/123 (Cardiac & Cardiovascular Systems)

Online ISSN: 1540-8175


  1. 1 - 100
  2. 101 - 130
  1. Original Investigations

    1. Carotid Ultrasound Maximum Plaque Height–A Sensitive Imaging Biomarker for the Assessment of Significant Coronary Artery Disease

      Amer M. Johri, Pearl Behl, Marie-France Hétu, Mohammad Haqqi, Paul Ewart, Andrew G. Day, Brendan Parfrey and Murray F. Matangi

      Article first published online: 29 JUN 2015 | DOI: 10.1111/echo.13007

    2. Aortic and Mitral Calcification Is Marker of Significant Carotid and Limb Atherosclerosis in Patients with First Acute Coronary Syndrome

      Anna Sannino, Maria-Angela Losi, Giuseppe Giugliano, Grazia Canciello, Evelina Toscano, Alessandra Giamundo, Fernando Scudiero, Linda Brevetti, Laura Scudiero, Maria Prastaro, Cinzia Perrino, Pasquale Perrone-Filardi, Maurizio Galderisi, Bruno Trimarco and Giovanni Esposito

      Article first published online: 29 JUN 2015 | DOI: 10.1111/echo.13006

    3. Diastolic Stunning as a Marker of Severe Coronary Artery Stenosis: Analysis by Speckle Tracking Radial Strain in the Resting Echocardiogram

      Hiroyo Kaseno, Takuji Toyama, Hiroki Okaniwa, Hiroyuki Toide, Eiji Yamashita, Ren Kawaguchi, Hitoshi Adachi, Hiroshi Hoshizaki and Shigeru Oshima

      Article first published online: 29 JUN 2015 | DOI: 10.1111/echo.12999

  2. Research from or in Collaboration with the University of Alabama at Birmingham

    1. Incremental Value of Live/Real Time Three-Dimensional Transesophageal Echocardiography over the Two-Dimensional Technique in the Assessment of Primary Cardiac Malignant Fibrous Histiocytoma

      Gulay Gok, Mahmoud Elsayed, Munveer Thind, Begum Uygur, Firoozeh Abtahi, Jugal R. Chahwala, Özlem Yıldırımtürk, İlyas Kayacıoğlu, Seçkin Pehlivanoğlu and Navin C. Nanda

      Article first published online: 26 JUN 2015 | DOI: 10.1111/echo.13005

  3. Original Investigations

    1. The Utility of Systolic and Diastolic Echocardiographic Parameters for Predicting Coronary Artery Disease Burden as Defined by the SYNTAX Score

      Shuangbo Liu, Motaz Moussa, Anthony W. Wassef, Brett M. Hiebert, Farrukh Hussain and Davinder S. Jassal

      Article first published online: 26 JUN 2015 | DOI: 10.1111/echo.12995

  4. Echo Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Routine Echo Follow-Up of the Patient after Transcatheter Aortic Valve Replacement

      Josh Grant, Hiren Patel, Frederick R. Helmcke and Edmund K. Kerut

      Article first published online: 25 JUN 2015 | DOI: 10.1111/echo.12980

  5. Case Reports

    1. TIA Caused by Contrast Echocardiography in Patient with Platypnea–Orthodeoxia

      Goran Loncar, Laurent Payot and Mathieu Dubois

      Article first published online: 24 JUN 2015 | DOI: 10.1111/echo.12970


      Platypnea-orthodeoxia syndrome (POS) is a rare clinical disorder characterized by dyspnea caused by the upright position and relieved at recumbent position. We present for the first time a patient with POS who experienced transitory ischemic attack (TIA) most likely caused by injection of agitated saline microbubbles during screen for PFO.

  6. Original Investigations

  7. Images Sections

    1. Giant Left Atrium with Large Thrombus—Comprehensive Evaluation and Management

      Prashanth Kumar Malkiwodeyar, Nagaraj Moorthy, Prabhavati Bhat and Manjunath Nanjappa Cholenahalli

      Article first published online: 22 JUN 2015 | DOI: 10.1111/echo.12984


      Forty-seven-year-old woman presented with NYHA class III symptoms of dyspnea on exertion with acute right lower limb ischemia, prompt surgical embolectomy was performed. Cardiac evaluation with echocardiography and 3D echocardiography revealed rheumatic heart disease—severe mitral stenosis with a giant left atrium with large mass occupying almost whole of left atrium. Detailed evaluation of the mass was performed to rule out malignancy with transesophageal echocardiography, computed tomography, and magnetic resonance imaging which were indicative of thrombus. Left atrial thrombectomy with mitral valve replacement was carried out, and histopathology confirmed the diagnosis of thrombus.

  8. Doppler Hemodynamics

    1. Spectral Doppler of the Hepatic Veins in Noncardiac Diseases: What the Echocardiographer Should Know

      Bahaa M. Fadel, Khadija Alassas, Aysha Husain, Ziad Dahdouh and Giovanni Di Salvo

      Article first published online: 22 JUN 2015 | DOI: 10.1111/echo.12994

  9. Case Reports

    1. Transient Apical Thickening Following Apical Ballooning Syndrome: A Case Series

      Muaz M. Abudiab, Susan Wilansky, Steven J. Lester, Rayan Yousefzai, Rochelle Tyler and A. Jamil Tajik

      Article first published online: 20 JUN 2015 | DOI: 10.1111/echo.13001


      The authors describe transient apical thickening mimicking apical hypertrophic cardiomyopathy following apical ballooning syndrome. These findings are observed on multimodality cardiac imaging and appear to constitute a novel entity. Possible pathophysiologic mechanisms are explored.

  10. Original Investigations

  11. Case Reports

    1. Three-Dimensional Transesophageal Echocardiography in the Anatomical Assessment of Isolated Parachute Mitral Valve in an Adult Patient

      Francisco López-Pardo, Jose Angel Urbano-Moral, Antonio González-Calle, Fernando Laviana-Martinez, Iris Esteve-Ruiz, Oscar Lagos-Degrande and Jose E. López-Haldon

      Article first published online: 20 JUN 2015 | DOI: 10.1111/echo.13003


      Parachute mitral valve(PMV) is a rare congenital anomaly of the mitral valve apparatus. Adult presentation is extremely rare. The echocardiographic examination identified a PMV. The report shows the usefulness of three-dimensional transesophageal echocardiography in the detection and quantification of this rare anomaly.

  12. Original Investigations

    1. Importance of End-Diastolic Rather than End-Systolic Right Atrial Size in Chronic Pulmonary Hypertension

      Angel Lopez-Candales, Denada S. Palm, Francisco R. Lopez, Reynerio Perez and Maria D. Candales

      Article first published online: 20 JUN 2015 | DOI: 10.1111/echo.12968

    2. Screening of Congenital Heart Diseases by Three-Dimensional Ultrasound Using Spatiotemporal Image Correlation: Influence of Professional Experience

      Juliana Y. Novaes, Marina M. Zamith, Edward Araujo Júnior, Enoch Q. de Sá Barreto, Fernanda S. B. Barros and Antonio F. Moron

      Article first published online: 20 JUN 2015 | DOI: 10.1111/echo.13002

    3. Right Ventricular Structure and Function in Idiopathic Pulmonary Fibrosis with or without Pulmonary Hypertension

      Antonello D'Andrea, Anna Stanziola, Enza Di Palma, Maria Martino, Michele D'Alto, Santo Dellegrottaglie, Rosangela Cocchia, Lucia Riegler, Meredyth Vanessa Betancourt Cordido, Maurizia Lanza, Marco Maglione, Veronica Diana, Raffaele Calabrò, Maria Giovanna Russo, Mani Vannan and Eduardo Bossone

      Article first published online: 11 JUN 2015 | DOI: 10.1111/echo.12992

    4. Left Atrial Dysfunction Assessed by Two-Dimensional Speckle Tracking Echocardiography in Patients with Impaired Left Ventricular Ejection Fraction and Sleep-Disordered Breathing

      Dawid Miśkowiec, Kupczyńska Karolina, Błażej W. Michalski, Barbara Uznańska-Loch, Małgorzata Kurpesa, Jarosław D. Kasprzak and Piotr Lipiec

      Article first published online: 8 JUN 2015 | DOI: 10.1111/echo.12987

  13. Image Sections

    1. Multiple Septal Coronary-Cameral Fistulae after Septal Myectomy

      Hayan Al Maluli, Moses Mathur, Martin G. Keane, T. Sloane Guy, Daniel Dries and Daniel Edmundowicz

      Article first published online: 8 JUN 2015 | DOI: 10.1111/echo.12989


      Coronary-cameral fistulae are rare after septal myectomy. Although most close spontaneously, their recognition is important as they may become clinically relevant if they persist.

  14. Original Investigations

    1. Assessment of Myocardial Function in Children before and after Autologous Peripheral Blood Stem Cell Transplantation

      Hala ElMarsafawy, Mohamed Matter, Mohamed Sarhan, Rasha El-Ashry and Youssef Al-Tonbary

      Article first published online: 8 JUN 2015 | DOI: 10.1111/echo.12988

    2. Utility of Isovolumic Contraction Peak Velocity for Evaluation of Adult Patient Status after Transcatheter Closure of Atrial Septal Defect

      Takuma Sawa, Hidekazu Tanaka, Yoshiki Motoji, Mana Hiraishi, Yasuhide Mochizuki, Keiko Ryo, Kensuke Matsumoto, Hiromasa Otake, Toshiro Shinke and Ken-ichi Hirata

      Article first published online: 6 JUN 2015 | DOI: 10.1111/echo.12982

    3. A New Method for Direct Three-Dimensional Measurement of Left Atrial Appendage Dimensions during Transesophageal Echocardiography

      Chaim Yosefy, Avishag Laish-Farkash, Yulia Azhibekov, Vladimir Khalameizer, Boris Brodkin and Amos Katz

      Article first published online: 6 JUN 2015 | DOI: 10.1111/echo.12983

    4. Comparison between Regional and Local Pulse-Wave Velocity Data

      Iana Simova, Tzvetana Katova, Ciro Santoro and Maurizio Galderisi

      Article first published online: 6 JUN 2015 | DOI: 10.1111/echo.12985

    5. The Value of Quality Improvement Process in the Detection and Correction of Common Errors in Echocardiographic Hemodynamic Parameters in a Busy Echocardiography Laboratory

      Zaher Fanari, Usman I. Choudhry, Vivek K. Reddy, Chete Eze-Nliam, Sumaya Hammami, Paul Kolm, William S. Weintraub and Erik S. Marshall

      Article first published online: 1 JUN 2015 | DOI: 10.1111/echo.12976

  15. Image Sections

    1. Transthoracic and Three-Dimensional Transesophageal Echocardiographic Presentation of Anomalous Circumflex Origin from Right Coronary Artery in Patient with Severe Mitral Stenosis

      Karina Wierzbowska-Drabik, Jan Zbigniew Peruga, Piotr Lipiec, Błażej Michalski and Jarosław Damian Kasprzak

      Article first published online: 28 MAY 2015 | DOI: 10.1111/echo.12981


      An origin of the circumflex coronary artery (Cx) from the right coronary artery or right Valsalva sinus is usually clinically silent coronary anomaly. Nevertheless, retroaortic course of aberrant Cx involving mitro-aortic continuity may become significant in the setting of mitral or aortic valve intervention, leading to compression of Cx and ischemic complication. For that reason, the early and accurate recognition of this anomaly is important and should be considered also during echocardiography. We described a man with severe mitral valve stenosis and anomalous Cx found during TEE on the base of detected “bleb sign” and retroaortic course of the artery.

    2. Left Ventricular Pseudoaneurysm after Aortic Valve Bypass Implantation

      Helle Søholm, Christian Hassager, Niels Vejlstrup, Henrik Arendrup, Maiken Jensen, Jens Lund and Nikolaj Ihlemann

      Article first published online: 26 MAY 2015 | DOI: 10.1111/echo.12975


      Aortic valve bypass (AVB)—a conduit from the apex of the left ventricle to the descending aorta containing a bioprosthetic valve—is a treatment option in severe aortic stenosis unsuitable for both surgical aortic valve replacement and transcatheter aortic valve replacement. An 82-year-old woman with severe aortic stenosis, porcelain aorta, and limited vascular access had an AVB inserted successfully. Imaging 3 months after implantation revealed a pseudoaneurysm at the AVB insertion site. Due to comorbidity and advanced age, the patient has been treated conservatively. Procedures with transapical insertions such as TAVI or AVB can lead to pseudoaneurysms, and the diagnosis often requires multiple imaging modalities.

  16. Original Investigations

  17. Case Reports

    1. An Unreported Congenital Anomaly: Aneurysm of the Lateral Half of the Mitral Valve

      Philippe Garcon, Yoan Lavie-Badie, Romain Cador, Olivier Bical and Adjé Abbey-Toby

      Article first published online: 22 MAY 2015 | DOI: 10.1111/echo.12964


      This case draws a new type of mitral valve anomaly. 3DTEE reveals that the lateral part of the valve is replaced by a fibrous aneurysm which seems to be congenital. We discuss differential diagnosis.

  18. Original Investigations

    1. Postprandial Hemodynamics in Hypertrophic Cardiomyopathy

      Jonathon C. Adams, John P. Bois, Mitsuru Masaki, Toshinori Yuasa, Jae K. Oh, Steve R. Ommen, Rick A. Nishimura and Kyle W. Klarich

      Article first published online: 22 MAY 2015 | DOI: 10.1111/echo.12951

  19. Echo Rounds Section Editor: Edmund Kenneth Kerut, M.D

    1. Cardiac Tamponade on the Edge

      Kavita P. Krishnasamy, Leon J. Frazin and Mayank Kansal

      Article first published online: 22 MAY 2015 | DOI: 10.1111/echo.12977


      Low-pressure cardiac tamponade is an uncommon phenomenon in the spectrum of pericardial diseases. We describe a case of a 37-year-old man with recurring admissions for dyspnea whose clinical picture challenged the classic exhibition of cardiac tamponade.

  20. Original Investigations

    1. Ratio of Acceleration Time to Ejection Time for Assessing Aortic Stenosis Severity

      Sergio Gamaza-Chulián, Santiago Camacho-Freire, Rocío Toro-Cebada, Alberto Giráldez-Valpuesta, Javier Benezet-Mazuecos and José Carlos Vargas-Machuca

      Article first published online: 22 MAY 2015 | DOI: 10.1111/echo.12978

  21. Image Sections

    1. An Unusual Case of Double-Orifice Mitral Valve Associated with D-Transposition of Great Arteries and Left-Side Heart Anomalies

      Placido Gitto, Elio Caruso, Luca Costanzo and Alfredo Di Pino

      Article first published online: 19 MAY 2015 | DOI: 10.1111/echo.12967


      We describe a very rare incidental echocardiography finding of double-orifice mitral valve in a newborn with prenatal diagnosis of D-transposition of great arteries, mild pulmonary valve stenosis, interventricular septal defect, and left superior cava vein draining into coronary sinus.

  22. Original Investigations

    1. Characteristics of Left Atrial Deformation Parameters and Their Prognostic Impact in Patients with Pathological Left Ventricular Hypertrophy: Analysis by Speckle Tracking Echocardiography

      Chiharuko Iio, Katsuji Inoue, Kazuhisa Nishimura, Akira Fujii, Takayuki Nagai, Jun Suzuki, Takafumi Okura, Jitsuo Higaki and Akiyoshi Ogimoto

      Article first published online: 8 MAY 2015 | DOI: 10.1111/echo.12961

  23. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Infective Endocarditis Complicated by Mitral Valve Aneurysm: Pathologic and Echocardiographic Correlations

      Arash Seratnahaei, Alison L. Bailey, Patrick J. Hensley, William O'Connor and Mikel D. Smith

      Article first published online: 30 APR 2015 | DOI: 10.1111/echo.12958

  24. Original Investigations

    1. Intervendor Variabilities of Left and Right Ventricular Myocardial Velocities among Three Tissue Doppler Echocardiography Systems

      Kiyoshi Abe, Satoshi Yuda, Yasumi Sato, Kenji Yasui, Ryosuke Nishi, Kyosuke Hanada, Naoko Hashimoto, Mina Kawamukai, Hidemichi Kouzu, Atsuko Muranaka, Akiyoshi Hashimoto, Kazufumi Tsuchihashi, Naoki Watanabe and Tetsuji Miura

      Article first published online: 29 APR 2015 | DOI: 10.1111/echo.12962

  25. Review Articles

  26. Original Investigations

    1. Assessment of Left Atrial Function in Patients with Celiac Disease

      Nermin Bayar, Ayhan Hilmi Çekin, Şakir Arslan, Göksel Çağırcı, Zehra Erkal, Serkan Çay, Erkan Köklü and Selçuk Küçükseymen

      Article first published online: 28 APR 2015 | DOI: 10.1111/echo.12963

  27. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Isolated Left Atrial Mechanical Standstill after Catheter Ablation of Atrial Fibrillation

      Edmund Kenneth Kerut, James McKinnie and Curtis Hanawalt

      Article first published online: 27 APR 2015 | DOI: 10.1111/echo.12956

  28. Image Sections

    1. Aorto–Left Atrial Fistula after Mitral Valve Surgery

      Mahmut Yesin, Macit Kalçık, Mustafa Ozan Gürsoy, Süleyman Karakoyun, Sabahattin Gündüz, Cengiz Köksal and Mehmet Özkan

      Article first published online: 27 APR 2015 | DOI: 10.1111/echo.12959


      The most common cardiac complications after prosthetic valve replacement include prosthetic valve endocarditis, thromboembolism, pericardial effusion, hemolysis, and valve failure due to prosthetic valve thrombosis or periprosthetic regurgitation. Aorto-atrial fistula after valve surgery is a rare complication, which usually occurs after aortic valve surgery. However, development of an aorto-left atrial fistula after prosthetic mitral valve replacement is very rare. Here, we present a patient who had aorto-atrial fistula evaluated by transesophageal echocardiography.

  29. Original Investigations

    1. The Relationship between Epicardial Fat Thickness and Endothelial Dysfunction in Type I Diabetes Mellitus

      Abdullah Nabi Aslan, Telat Keleş, Hüseyin Ayhan, Hacı Ahmet Kasapkara, Murat Akçay, Tahir Durmaz, Cenk Sarı, Serdal Baştuğ, Bekir Çakır and Engin Bozkurt

      Article first published online: 27 APR 2015 | DOI: 10.1111/echo.12960

  30. Case Reports

    1. An Unusual Cause of Cardioembolic Stroke: Paradoxical Embolism Due to Thrombus Formation on the Eustachian Valve

      Mohamed ElRefai, Karthika Thananayagam, Rajaram Bathula and Benoy N. Shah

      Article first published online: 20 APR 2015 | DOI: 10.1111/echo.12945


      Cardioembolism is an important cause of ischemic stroke. Paradoxical embolism is a rare cause of cardioembolic stroke. We report the first case of a patient with presumed paradoxical cardioembolic stroke secondary to thrombus formation on the eustachian valve remnant. The patient was anticoagulated with resolution of the mass upon follow-up assessment. Physicians are reminded of the utility of echocardiography for identifying potential cardioembolic etiologies, including both transthoracic and transoesophageal echocardiography.

  31. Original Investigations

  32. Case Reports

    1. Rare Mycotic Aneurysm of the Mitral Valve without Aortic Valve Involvement

      Parham Zarrini, Omeed Elboudwarej, Daniel Luthringer and Robert Siegel

      Article first published online: 16 APR 2015 | DOI: 10.1111/echo.12942


      Mycotic aneurysms can be a rare, but serious complication of infectious endocarditis. We report the case of a 20-year-old woman who presented with fever and malaise from streptococcal bacteremia and found to have vegetation on the anterior leaflet of the mitral valve. On follow-up visit, the patient was noted to have a mycotic aneurysm of the anterior mitral valve without aortic involvement. Her clinical course was complicated by mitral valve chordal rupture, severe mitral regurgitation, and dyspnea from severe mitral regurgitation for which she underwent successful surgical repair of the mitral valve.

  33. Original Investigations

    1. Determinants of Secondary Pulmonary Hypertension in Patients with Takotsubo Cardiomyopathy

      Masaki Izumo, Maiko Shiota, Smruti Nalawadi, Jayanta Das, Sohail Dohad, Eiji Kuwahara, Yoko Fukuoka, Robert J Siegel and Takahiro Shiota

      Article first published online: 16 APR 2015 | DOI: 10.1111/echo.12949

  34. Echo Rounds Section Editor: Edmund Kenneth Kerut, M.D

    1. Role of Four-Dimensional Transesophageal Echocardiography in Diagnosis of Mechanical Tricuspid Valve Obstruction Due to Thrombus

      Henry C. Quevedo, Rohan Samson, Zhaohui Li, Ghassan Mohsen, Frederick Helmcke, Edmund K. Kerut and Gary E. Sander

      Article first published online: 15 APR 2015 | DOI: 10.1111/echo.12953

  35. Image Sections

    1. An Unexpected Guest in the Proximal Ascending Aorta

      Laura Toffetti, Alice Pugno, Laura Massironi, Silvia Tresoldi and Antonio G. Mantero

      Article first published online: 15 APR 2015 | DOI: 10.1111/echo.12952


      A 72-year-old asymptomatic woman with history of ischemic heart disease and repeat coronary percutaneous interventions underwent a routine transthoracic echocardiogram (TTE). A 9-mm long, fixed, echo dense mass was visualized in the proximal ascending aorta. We performed a two and three-dimensional transesophageal echocardiogram and a cardiac multidetector-row contrast-enhanced computed tomography with ECG gating, which revealed the unexplained mass to be an ostial right coronary artery stent protruding 9 mm into the ascending aorta. Coronary stent protrusion is a very unusual finding observed during routine 2DTTE, but it has many potential clinical consequences. This case suggests that 2DTTE is feasible and useful for the identification and follow-up of protruding ostial coronary stents.

    2. Giant Aneurysm of Aortic Right Coronary Sinus: Diagnostic Doubts Related to Presentation of Valsalva Sinus Aneurysm in Transthoracic Echocardiography

      Karina Wierzbowska-Drabik, Jarosław D. Kasprzak, Konrad Szymczyk, Ewa Szymczyk, Katarzyna Wdowiak-Okrojek and Piotr Lipiec

      Article first published online: 15 APR 2015 | DOI: 10.1111/echo.12950


      We present the images of giant aneurysm of Valsalva sinus (SVA) in 79-year-old woman that was not diagnosed in first transthoracic echocardiographic study, because of problematic presentation suggesting defect of aortic wall or additional structure inside right ventricle. Although the majority of aneurysm of Valsalva sinuses are diagnosed by echocardiography, our case illustrates diagnostic doubts evoked by big aneurysm which seemed to fill completely right ventricular cavity. Nevertheless, repeated detailed examination with support of 3D technique and verification by computed tomography elucidated the correct diagnosis. On grounds of high surgical risk, the patient was classified for treatment with losartan and echocardiographic monitoring.

  36. Original Investigations

    1. Incremental Value of Pocket-Sized Echocardiography in Addition to Physical Examination during Inpatient Cardiology Evaluation: A Multicenter Italian Study (SIEC)

      Vitantonio Di Bello, Salvatore La Carrubba, Lorenzo Conte, Iacopo Fabiani, Alfredo Posteraro, Francesco Antonini-Canterin, Valentina Barletta, Irene Nicastro, Egidio Mariotti, Sergio Severino, Pio Caso, Frank Benedetto, Ketty Savino, Scipione Carerj and on behalf of SIEC (Italian Society of Cardiovascular Echography)

      Article first published online: 12 APR 2015 | DOI: 10.1111/echo.12910

  37. Review Articles

    1. The Various Hemodynamic Profiles of the Patent Ductus Arteriosus in Adults

      Bahaa M. Fadel, Dania Mohty, Aysha Husain, Ziad Dahdouh, Mohammad Al-Admawi, Valeria Pergola and Giovanni Di Salvo

      Article first published online: 12 APR 2015 | DOI: 10.1111/echo.12943

  38. Original Investigations

    1. Real Time Three-Dimensional Echocardiographic Evaluations of Fetal Left Ventricular Stroke Volume, Mass, and Myocardial Strain: In Vitro and In Vivo Experimental Study

      Meihua Zhu, Muhammad Ashraf, Zhijun Zhang, Cole Streiff, Eriko Shimada, Sumito Kimura, Traci Schaller, Xubo Song and David J. Sahn

      Article first published online: 11 APR 2015 | DOI: 10.1111/echo.12939

  39. Image Sections

    1. Aortic Fibroelastoma: Detailed Preoperative Analysis with 3D Echocardiography

      José Luis Moya-Mur, Jacobo Silva-Guisasola, Eduardo Casas-Rojo, Miren Martín-García, Carmen de Pablo-Zarzosa, José Julio Jiménez-Nacher and José Luis Zamorano-Gomez

      Article first published online: 11 APR 2015 | DOI: 10.1111/echo.12940


      A 70-year-old man submitted to a routine echocardiogram was diagnosed of an aortic mass by transthoracic echocardiography. Three-dimensional transesophageal echocardiography (3DTEE) revealed a mobile and pedunculated mass attached to the noncoronary cusp of the aortic valve, suggestive of an aortic fibroelastoma. 3DTEE allowed a perfect characterization of the tumor. Because of their size and mobility, surgical resection was advised. Surgery confirmed the diagnosis of aortic fibroelastoma and showed the utility of 3DTEE to take the correct therapeutic attitude.

  40. Original Investigations

    1. The Effect of Habitual Physical Training on Left Ventricular Function During Exercise Assessed by Three-Dimensional Echocardiography

      Mari Sugiura Kojima, Akiko Noda, Seiko Miyata, Jun Kojima, Yuki Hara, Makoto Minoshima and Toyoaki Murohara

      Article first published online: 27 MAR 2015 | DOI: 10.1111/echo.12934

    2. Significant Reduction in Mitral Regurgitation Volume Is the Main Contributor for Increase in Systolic Forward Flow in Patients with Functional Mitral Regurgitation after Transcatheter Aortic Valve Replacement: Hemodynamic Analysis Using Echocardiography

      Yuji Itabashi, Kentaro Shibayama, Hirotsugu Mihara, Hiroto Utsunomiya, Javier Berdejo, Reza Arsanjani, Robert Siegel, Tarun Chakravarty, Hasan Jilaihawi, Raj R. Makkar and Takahiro Shiota

      Article first published online: 26 MAR 2015 | DOI: 10.1111/echo.12936

  41. Case Reports

    1. Trileaflet Mitral Valve with Three Papillary Muscles Associated with Hypertrophic Cardiomyopathy: A Novel Case

      Salvatore Rosanio, Cameron J. Simonsen, John Starwalt, Abdul M. Keylani and Antonio Vitarelli

      Article first published online: 25 MAR 2015 | DOI: 10.1111/echo.12938


      A trileaflet mitral valve with three separate papillary muscles with concordant atrioventricular and ventricle–arterial connections is exceptionally rare. To the best of the authors' knowledge, it has been reported only once in association with subaortic valvular stenosis. We hereby describe a novel case associated with hypertrophic cardiomyopathy.

  42. Case Reports – Pediatric

    1. Aortic Arch Interruption and Persistent Fifth Aortic Arch in Phace Syndrome: Prenatal Diagnosis and Postnatal Course

      Enrico Chiappa, Antonella Greco, Valentina Fainardi, Silvia Passantino, Daniele Serranti and Silvia Favilli

      Article first published online: 25 MAR 2015 | DOI: 10.1111/echo.12941


      PHACE syndrome is a rare congenital neurocutaneous disease where posterior fossa malformations, hemangiomas, cerebrovascular anomalies, aortic arch anomalies, cardiac defects, and eye abnormalities are variably associated. We describe the prenatal detection and the postnatal course of a child with PHACE syndrome with a unique type of aortic arch anomaly consisting of proximal interruption of the aortic arch and persistence of the fifth aortic arch. The fifth aortic arch represented in this case a vital systemic-to-systemic connection between the ascending aorta and the transverse portion of the aortic arch allowing adequate forward flow through the aortic arch without surgical treatment.

  43. Original Investigations

    1. Clinical Evaluation of Coronary In-Stent Restenosis Using Dual-Source Computed Tomography

      Lian-Fa Wang, Li-Wei Tao, Meng-Xun Huang, Wen-Bin Liao, You-Zhi Zhu, Wen-Bing Zhou, Hua Li, Dan Li, Hong-Tao Lu, Bang-Zhu Zhang and Zhen Chen

      Article first published online: 25 MAR 2015 | DOI: 10.1111/echo.12932

  44. Image Sections

    1. Swiss Cheese-Like Atrial Septal Defect Detected by Three-Dimensional Echocardiography

      Mehmet A. Vatankulu, Parviz Jafarov and Nuray Kahraman Ay

      Article first published online: 25 MAR 2015 | DOI: 10.1111/echo.12933


      A 33-year-old female presented to the outpatient clinic with progressive exertional dyspnea. Transthoracic echocardiography revealed enlarged right heart chambers with left-to-right shunting. Two-dimensional transesophageal echocardiography confirmed these findings and showed three defects on interatrial septum. Real time three-dimensional transesophageal echocardiography was performed to better visualize the anatomy of the interatrial septum. Reconstruction of the three-dimensional images revealed multiple defects of interatrial septum like a Swiss cheese. The patient underwent surgical closure of the atrial septal defect.

  45. Original Investigations

    1. Left Ventricular Twist Mechanics Are Impaired in Patients with Coronary Slow Flow

      Ahmet Barutçu, Adem Bekler, Ahmet Temiz, Bahadır Kırılmaz, Ali Ümit Yener, Yusuf Ziya Tan, Emine Gazi and Burak Altun

      Article first published online: 4 MAR 2015 | DOI: 10.1111/echo.12918

  46. Case Reports

    1. Imaging Tuberous Sclerosis: The Incremental Benefit of Three-Dimensional and Speckle Tracking Echocardiography

      Pankaj Garg, Tarique A. Musa and David P. Ripley

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12921


      Transthoracic echocardiography is established as the primary imaging modality for detection of cardiac rhabdomyomas. The precise functional assessment of the left ventricle in these patients requires clarification. We report a case with multiple rhabdomyomas (on 3D echocardiography) and normal ejection fraction but altered global and regional deformation on speckle tracking. The regional longitudinal strain was notably reduced in the anterior septum (−11%) and inferior septum −15%). The global circumferential strain (GCS) was significantly reduced at −15.6%. The distribution of regional circumferential strain reduction for the mid-ventricular segment correlated with the location of cardiac rhabdomyomas.

    2. Giant Purulent Pericarditis with Cardiac Tamponade Due to Streptococcus intermedius Rapidly Progressing to Constriction

      Elif T. Tigen, Ibrahim Sari, Koray Ak, Sena Sert, Kursat Tigen and Volkan Korten

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12919


      Purulent pericardial effusion, although rare, is a life-threatening condition usually produced by the extension of a nearby bacterial infection locus or by blood dissemination in the immune-suppressed subjects or in the course of cardiothoracic surgery. Because clinical features of purulent pericardial effusion are often nonspecific, it can cause delay in diagnosis. Therefore, a high index of suspicion is required for timely diagnosis and management. Herein, we describe a case of giant purulent pericardial effusion due to Streptococcus intermedius with the history of bronchiectasis and pneumonia, which was successfully treated with pericardiocentesis via parasternal approach, appropriate antibiotics, and pericardiectomy.

    3. Unruptured Sinus of Valsalva Aneurysm with Right Ventricular Outflow Tract Obstruction and Ventricular Septal Defect—A Rare Combination

      Sambhunath Das, Suruchi Ladha and Balram Airan

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12920


      Sinus of Valsalva aneurysms are rare cardiac anomalies which may be acquired or congenital. We describe the case of a patient who had an unruptured sinus of Valsalva aneurysm causing right ventricular outflow obstruction, with an associated subaortic ventricular septal defect. Sinus of Valsalva aneurysms rarely present until rupture occur. However, the unruptured aneurysm of the right sinus of Valsalva caused significant right ventricular outflow tract obstruction, resulting in exertional dyspnea. Intraoperative multiplane transesophageal echocardiography and color Doppler helped in precise identification of structural anomalies, shunt location, and definitive surgical repair.

    4. Isolated Left Ventricular Diastolic Collapse Due to Extra-Thoracic Compression

      Rana Costa, Jad Zahnan, Hadi Skouri, Walid Gharzuddine, Lara Al-Masri, Chakib Ayyoub and Antoine B. Abchee

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12913


      Isolated collapse of the left ventricle (LV) in diastole is not a very common finding on two-dimensional echocardiography. Reported cases in the literature were due to either loculated postoperative pericardial effusion/hematoma or left pleural effusion. To our knowledge, this is the first case report of LV diastolic collapse secondary to extra-thoracic compression.

  47. Original Investigations

    1. Impact of Severe Tricuspid Regurgitation on Accuracy of Echocardiographic Pulmonary Artery Systolic Pressure Estimation

      Ebru Özpelit, Bahri Akdeniz, Emre Mehmet Özpelit, Sedat Tas, Erkan Alpaslan, Selen Bozkurt, Abdulla Arslan and Özer Badak

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12912

    2. Atrial Septal Aneurysms and Supraventricular Arrhythmias: The Role of Atrial Electromechanical Delay

      Vincenzo Russo, Anna Rago, Federica Di Meo, Andrea Antonio Papa, Carmine Ciardiello, Anna Cristiano, Raffaele Calabrò, Maria Giovanna Russo and Gerardo Nigro

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12908

    3. Four-Dimensional Speckle Tracking Echocardiography in Patients with Hypertrophic Cardiomyopathy

      Kadriye Orta Kilickesmez, Onur Baydar, Cem Bostan, Ugur Coskun and Serdar Kucukoglu

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12916

    4. Relationship between Epicardial Adipose Tissue Thickness and Atrial Electromechanical Delay in Hypertensive Patients

      Ahmet Akyel, Kadriye G. Yayla, Mehmet Erat, Hamza Sunman, Mehmet Doğan, Tolga Çimen, Mehmet Aytürk and Ekrem Yeter

      Article first published online: 3 MAR 2015 | DOI: 10.1111/echo.12917

    5. Accuracy of Echocardiographic Cardiac Index Assessment in Subjects with Preserved Left Ventricular Ejection Fraction

      Micha T. Maeder, Sofie Karapanagiotidis, Elizabeth M. Dewar and David M. Kaye

      Article first published online: 1 MAR 2015 | DOI: 10.1111/echo.12928

  48. Case Reports

    1. A Case Report of Double-Chambered Right Ventricle Associated with Subaterial Ventricular Septal Defect and Rupture of Right Coronary Sinus Aneurysm

      Guobing Hu, Xiangming Zhu, Guojie Li, Feng Jiang and Jing Li

      Article first published online: 1 MAR 2015 | DOI: 10.1111/echo.12923


      Double-chambered right ventricle (DCRV) is a rare congenital heart disease. We report a case of DCRV associated with subarterial ventricular septal defect (VSD) and rupture of right coronary sinus aneurysm (RCSA); the patient was diagnosed by echocardiography and later confirmed by surgical operation.

  49. Original Investigations

    1. Interatrial Dyssynchrony May Contribute to Heart Failure Symptoms in Patients with Preserved Ejection Fraction

      Laura Sanchis, Luca Vannini, Luigi Gabrielli, Nicolas Duchateau, Carles Falces, Rut Andrea, Bart Bijnens and Marta Sitges

      Article first published online: 1 MAR 2015 | DOI: 10.1111/echo.12927

    2. Tricuspid Annular Plane Systolic Excursion and Its Association with Mortality in Critically Ill Patients

      Deepakraj Gajanana, Harish Seetha Rammohan, Oluseun Alli, Abel Romero-Corral, Bhaskar Purushottam, Shiva Ponamgi, Vincent M. Figueredo and Gregg S. Pressman

      Article first published online: 1 MAR 2015 | DOI: 10.1111/echo.12926

    3. Assessment of Myocardial Infarct Size by Three-Dimensional and Two-Dimensional Speckle Tracking Echocardiography: A Comparative Study to Single Photon Emission Computed Tomography

      Qiushuang Wang, Dangsheng Huang, Liwei Zhang, Dong Shen, Qiaohong Ouyang, Zhongxiang Duan, Xiuzhi An, Meiqing Zhang, Chunhong Zhang, Feifei Yang and Guang Zhi

      Article first published online: 15 FEB 2015 | DOI: 10.1111/echo.12901

    4. Feasibility and Diagnostic Potential of Pulmonary Transit Time Measurement by Contrast Echocardiography: A Pilot Study

      Evan L. Brittain, Laura N. Doss, Linda Saliba, Waleed Irani, Benjamin F. Byrd III and Ken Monahan

      Article first published online: 13 FEB 2015 | DOI: 10.1111/echo.12906

    5. Prognostic Value of Pericardial Effusion on Serial Echocardiograms in Pulmonary Arterial Hypertension

      Omar Batal, Zeina Dardari, Chelcie Costabile, John Gorcsan, Vincent C. Arena and Michael A. Mathier

      Article first published online: 13 FEB 2015 | DOI: 10.1111/echo.12909

    6. Association of Left Atrial Spontaneous Echo Contrast to Uric Acid in Patients with Mitral Stenosis

      Mahmut Akpek, Omer Sahin, Bahadir Sarli, Huseyin Arinc, Ahmet O. Baktir, Zeynep S. Akpek, Hayrettin Saglam, Ali Ergin and Mehmet G. Kaya

      Article first published online: 2 FEB 2015 | DOI: 10.1111/echo.12897

  50. Case Reports

    1. A Case of Giant Mediastinal Cyst Initially Detected and Diagnosed by Echocardiography

      XiaoDong Li, XiaoCong Wang, XiuMei Duan and Hui Xu

      Article first published online: 30 JAN 2015 | DOI: 10.1111/echo.12884


      The diagnoses of mediastinal cysts are primarily depended on x-ray and computed tomography. The development of ultrasound instruments in recent years has led to improved detection rates of mediastinal lesions. We report a case of a mediastinal cyst that was first detected and diagnosed on thoracic echocardiography examination.

  51. Original Investigations

  52. Doppler Hemodynamics

    1. Spectral Doppler Interrogation of Mitral Regurgitation —Spot Diagnosis

      Bahaa M. Fadel, Hatem Bakarman, Ziad Dahdouh, Giovanni Di Salvo and Dania Mohty

      Article first published online: 22 JAN 2015 | DOI: 10.1111/echo.12891

  53. Original Investigations

    1. Right and Left Atrial Dissimilarities in Normal Subjects Explored by Speckle Tracking Echocardiography

      Sherif Moustafa, Hamed Zuhairy, Mostafa A. Youssef, Nanette Alvarez, Michael S. Connelly, Timothy Prieur and Farouk Mookadam

      Article first published online: 21 JAN 2015 | DOI: 10.1111/echo.12880

    2. Echo Doppler Estimation of Pulmonary Capillary Wedge Pressure in Patients with Severe Aortic Stenosis

      Simon Biner, Yan Topilsky, Shmuel Banai, Arie Steinvil, Yaron Arbel, Robert James Siegel, Roy Beigel, Gad Keren and Ariel Finkelstein

      Article first published online: 21 JAN 2015 | DOI: 10.1111/echo.12893

    3. Training Program for Cardiology Residents to Perform Focused Cardiac Ultrasound Examination with Portable Device

      Vicente N. Siqueira, Frederico J. N. Mancuso, Orlando Campos, Angelo A. De Paola, Antonio C. Carvalho and Valdir A. Moises

      Article first published online: 21 JAN 2015 | DOI: 10.1111/echo.12887

    4. Characterization of Left Atrial Mechanics in Hypertrophic Cardiomyopathy and Essential Hypertension Using Vector Velocity Imaging

      Hala Mahfouz Badran, Naglaa Faheem, Mohamed Fahmy Elnoamany, Asma Kenawy and Magdi Yacoub

      Article first published online: 20 JAN 2015 | DOI: 10.1111/echo.12885

  54. Case Reports

    1. Congenital Absence of the Left Atrial Appendage Visualized by 3D Echocardiography in Two Adult Patients

      Mona Saleh, Revathi Balakrishnan, Leticia Castillo Kontak, Ricardo Benenstein, Larry A. Chinitz, Robert Donnino and Muhamed Saric

      Article first published online: 14 JAN 2015 | DOI: 10.1111/echo.12882


      Congenital absence of left atrial appendage (LAA) is a rare condition with unknown physiological consequences. We present two cases of incidental finding of a congenitally absent LAA in two adult patients. Congenitally absent LAA may be confused with flush thrombotic occlusion of the appendage. There are very few published reports of congenital absence of LAA, and our report is the first to demonstrate this absence by 3DTEE.

    2. Sustained Ventricular Tachycardia as the First Manifestation of Hydatid Cyst Located in the Interventricular Septum

      İrfan Şahin, Berk Özkaynak, Bariş Güngör, Burak Ayça, Serhat Sığirci, Bülent Mert and Ertuğrul Okuyan

      Article first published online: 14 JAN 2015 | DOI: 10.1111/echo.12894


      Echinococcus granulosus infection may manifest with cardiac involvement causing various symptoms. Here, we discuss a case of a young patient who presented with sustained ventricular tachycardia (VT) causing hemodynamic compromise. Diagnosis of cardiac hydatid cyst was established with echocardiography, computed tomography imaging, and serological examination. After surgical removal of the cyst VT did not recur.

  55. Original Investigations

    1. Effects of Hemodialysis on Tei Index: Comparison between Flow Doppler and Tissue Doppler Imaging

      Demet Menekse Gerede, Sibel Turhan, Cansin Tulunay Kaya, Ozgur Ulas Ozcan, Huseyin Goksuluk, Veysel Kutay Vurgun, Irem Dincer, Sim Kutlay, Sehsuvar Erturk and Cetin Erol

      Article first published online: 14 JAN 2015 | DOI: 10.1111/echo.12895

  56. Case Reports

    1. A Case of Late Presenting Unicuspid Aortic Valve in a 62-Year-Old Female

      Rebecca Chester, Sheila Sahni and Tracy Huynh

      Article first published online: 14 JAN 2015 | DOI: 10.1111/echo.12881


      We describe a case of a 62-year old female with newly diagnosed severe aortic stenosis and is found to have a unicuspid aortic valve. Transesophageal echocardiography suggested a bicuspid aortic valve, however surgical valve replacement revealed the valve to be unicuspid. This case report provides discussion of epidemiology of unicuspid aortic valves as well as current imaging modalities used for diagnosis of aortic valve pathology.

  57. Original Investigations

    1. Prevalence of Left Ventricular Dyssynchrony in Patients with Congenital Atrioventricular Block and Long-Term Pacing: A Three-Dimensional Echocardiographic Study

      Vitor Coimbra Guerra, Luciana de Menezes Martins, Roberto Marcio Oliveira, Kátia Regina da Silva, Maria Angelica Binotto, Jeane M. Tsutsui, Roberto Kallil, Roberto Costa and Wilson Mathias Jr

      Article first published online: 14 JAN 2015 | DOI: 10.1111/echo.12871

  58. Case Reports

    1. Early Recognition of Apical Ballooning Syndrome by Global Longitudinal Strain Using Speckle Tracking Imaging—The Evil Eye Pattern, a Case Series

      Sualy Sosa and Jose Banchs

      Article first published online: 2 JAN 2015 | DOI: 10.1111/echo.12875


      In this case series we report 4 cases of patients diagnosed with stress induced cardiomyopathy apical ballooning syndrome (ABS), who presented to our institution with chest pain, mildly elevated cardiac enzymes and ischemic electrocardiographic changes. They were found to have severe hypokinesis or akinesis of the mid to apical segments with dynamic basal segments on echocardiography. A global longitudinal strain (GLS) pattern on polar map was markedly different from the pattern of proximal left anterior descending artery (LAD) myocardial infarction. All of them had a similar GLS pattern on presentation, which was easy to recognize on these polar maps images the day of the event. We discuss the usefulness of early recognition of ABS using global longitudinal strain images.

    2. An Unusual Mass of Tricuspid Valve in an Adult Patient: Blood-Filled Cyst

      Macit Kalçık, Mahmut Yesin, Mustafa Ozan Gürsoy, Süleyman Karakoyun, Sinan Cerşit, Cengiz Köksal, Cemil İzgi and Mehmet Özkan

      Article first published online: 2 JAN 2015 | DOI: 10.1111/echo.12878


      Blood-filled cysts (BFC) within the heart are very rare entities in adolescents and adults. Here, an adult case of BFC attached to the posterior leaflet of the tricuspid valve is reported, demonstrating the importance of multimodal diagnostic imaging combining both echocardiography and magnetic resonance imaging.

  59. Original Investigations

    1. Exploring Noninvasive Tricuspid dP/dt as a Marker of Right Ventricular Function

      Yash Singbal, William Vollbon, Luan Tan Huynh, William Y. S. Wang, Arnold C. T. Ng and Sudhir Wahi

      Article first published online: 2 JAN 2015 | DOI: 10.1111/echo.12877

    2. Novel Echocardiographic Indices as Predictors of Immediate Recurrence after Undersized Ring Annuloplasty for Ischemic Mitral Regurgitation

      Shokoufeh Hajsadeghi, Niloufar Samiee, Seyyed Saied Hosseini, Morteza Hassanzadeh and Scott Reza Jafarian Kerman

      Article first published online: 2 JAN 2015 | DOI: 10.1111/echo.12879

    3. Prognostic Value of Stress Echocardiography in Patients Presenting with Syncope

      Jose Ricardo F. Po, Farooq A. Chaudhry, Kiruthika Balasundaram, Waseem Shami, Sunil Penesetti, Kiran K. Kommaraju, Sameh Mohareb, Suketukumar Patel, Vikram Agarwal and Edgar Argulian

      Article first published online: 2 JAN 2015 | DOI: 10.1111/echo.12874


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