Cover image for Vol. 31 Issue 9

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Navin C. Nanda

Impact Factor: 1.254

ISI Journal Citation Reports © Ranking: 2013: 89/125 (Cardiac & Cardiovascular Systems)

Online ISSN: 1540-8175


  1. 1 - 100
  2. 101 - 165
  1. Original Investigations

    1. Right Ventricular Strain before and after Pulmonary Thromboendarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension

      Nicholas Marston, Jason P. Brown, Nicholas Olson, William R. Auger, Michael M. Madani, Darrin Wong, Ajit B. Raisinghani, Anthony N. DeMaria and Daniel G. Blanchard

      Article first published online: 18 OCT 2014 | DOI: 10.1111/echo.12812

  2. ECHO Round Section Editor: Edmund Kenneth Kerut, M.D.

    1. Pseudoaneurysm in the Mitral–Aortic Intervalvular Fibrosa—Case Report and Literature Review

      Oana Năstase, Bogdan Rădulescu, Marinela Şerban, Ioana Smărăndiţa Lăcău, Şerban Bubenek, Bogdan Alexandru Popescu, Carmen Ginghinã and Ruxandra Jurcuţ

      Article first published online: 18 OCT 2014 | DOI: 10.1111/echo.12807

  3. Case Reports

    1. Fetal and Neonatal Imaging and Strategy of Primary Neonatal Heart Transplantation in Hypoplastic Left Heart with Ebstein's Anomaly

      James M. Hammel, David A. Danford, Robert L. Spicer and Shelby Kutty

      Article first published online: 18 OCT 2014 | DOI: 10.1111/echo.12820


      We report a case of mitral stenosis/aortic atresia variant of hypoplastic left heart syndrome, Ebstein's anomaly, and partial anomalous pulmonary venous return. The prenatal and postnatal echocardiography findings guided therapy toward primary transplantation rather than conventional staged surgical palliation.

  4. Original Investigations

    1. Quantification of Mitral Regurgitation by Real Time Three-Dimensional Color Doppler Flow Echocardiography Pre– and Post–Percutaneous Mitral Valve Repair

      Christiane Gruner, Bernhard Herzog, Dominique Bettex, Christian Felix, Saurabh Datta, Matthias Greutmann, Oliver Gaemperli, Simon A. Müggler, Felix C. Tanner, Juerg Gruenenfelder, Roberto Corti and Patric Biaggi

      Article first published online: 18 OCT 2014 | DOI: 10.1111/echo.12809

    2. Early Improvement in Left Atrial Remodeling and Function after Mitral Valve Repair or Replacement in Organic Symptomatic Mitral Regurgitation Assessed by Three-Dimensional Echocardiography

      David C. S. Le Bihan, Dorival Julio Della Togna, Rodrigo B. M. Barretto, Jorge Eduardo Assef, Lúcia Romero Machado, Auristela Isabel de Oliveira Ramos, Camilo Abdulmassih Neto, Valdir Ambrosio Moisés, Amanda G. M. R. Sousa and Orlando Campos

      Article first published online: 18 OCT 2014 | DOI: 10.1111/echo.12817

    3. Effects of Transcatheter Aortic Valve Implantation on Left Ventricular and Left Atrial Morphology and Function

      Antonello D'Andrea, Roberto Padalino, Rosangela Cocchia, Enza Di Palma, Lucia Riegler, Raffaella Scarafile, Giovanni Rossi, Renato Bianchi, Donato Tartaglione, Maurizio Cappelli Bigazzi, Paolo Calabrò, Rodolfo Citro, Eduardo Bossone, Raffaele Calabrò and Maria Giovanna Russo

      Article first published online: 17 OCT 2014 | DOI: 10.1111/echo.12808

  5. Image Sections

    1. A Distinctly Rare Case of Candida Endocarditis Involving the Bioprosthetic Pulmonary and the Eustachian Valve Diagnosed on 3D Transesophageal Echocardiography

      Ahmed K. Pasha, Branden A. Snyder, Tirdad T. Zangeneh, Jess L. Thompson, Richard E. Sobonya and Aiden Abidov

      Article first published online: 17 OCT 2014 | DOI: 10.1111/echo.12804


      We describe a unique case where a 53-year-old man with history of intravenous drug abuse and prior endocarditis presented with fever and chest pain. He was found to have a eustachian valve vegetation and bioprosthetic pulmonary valve vegetation. The causative organism was Candida albicans. In this case, three-dimensional transesophageal echocardiography clearly identified the pulmonic valve vegetation which was not well seen on two-dimensional transthoracic echocardiography.

  6. Original Investigations

    1. Reference Values for Right Ventricular Strain in Patients without Cardiopulmonary Disease: A Prospective Evaluation and Meta-Analysis

      Nowell M. Fine, Libo Chen, Paul M. Bastiansen, Robert P. Frantz, Patricia A. Pellikka, Jae K. Oh and Garvan C. Kane

      Article first published online: 17 OCT 2014 | DOI: 10.1111/echo.12806

  7. Case Reports

    1. Blunt Chest Trauma Resulting in Both Atrial and Ventricular Septal Defects

      Yahaira Ortiz, Adam J. Waldman, Jeff N. Bott, Steve J. Carlan and Mario Madruga

      Article first published online: 17 OCT 2014 | DOI: 10.1111/echo.12801


      Disruption of both the atrial and ventricular walls occurred after violent blunt chest trauma.

  8. Image Sections

    1. Post-TAVR Ventricular Septal Defect in the Presence of Subaortic Membrane

      Christina W. Lee, Sheila M. Hegde, Steven M. Ewer and Lucian Lozonschi

      Article first published online: 17 OCT 2014 | DOI: 10.1111/echo.12802


      Transcatheter aortic valve replacement (TAVR) has traditionally been reserved for patients who are high-risk with significant comorbid conditions. We present a case of an 80-year-old female who sustained a small, restrictive ventricular septal defect (VSD) following TAVR. This patient was thoroughly evaluated preoperatively and the decision was made to proceed with nonconventional repair given significant comorbid conditions in conjunction with subvalvular stenosis secondary to a subvalvular membrane. The objective of this presentation is to direct special focus to the echocardiographic images of this unique case in the setting of this unique anatomic variant.

  9. Original Investigations

    1. The Effect of Transcatheter Aortic Valve Implantation on Pulmonary Hypertension

      Tahir Durmaz, Hüseyin Ayhan, Telat Keleş, Abdullah Nabi Aslan, Hacı Ahmet Kasapkara, Cenk Sarı, Emine Bilen, Nihal Akar Bayram, Murat Akçay and Engin Bozkurt

      Article first published online: 16 OCT 2014 | DOI: 10.1111/echo.12811

  10. Research from or in Collaboration with the University of Alabama at Birmingham

  11. Case Reports

    1. Prenatal Diagnosis of Giant Left Ventricular Diverticulum: Case Report

      Fadli Demir, Nazan Ozbarlas, Uğur Gocen and Selim Buyukkurt

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12781


      The distinction between a ventricular aneurysm and diverticulum is difficult. The differences between these two are based on anatomical, histological, and functional criteria. We present a case of prenatal diagnosis of a giant left ventricular outpouching at 28 weeks gestation. During the postnatal period, the neonate underwent surgical correction for the outpouching. Histopathological examination reported the resected segment was a cardiac diverticulum. Our case indicates that differentiating between the two diagnoses during the intrauterine period is not always straightforward and possible. Histopathological examinations are sometimes necessary to make a precise differentiation. Treatment should be individualized depending on the clinical presentation.

  12. Original Investigations

    1. Left Ventricular Mechanics in Untreated Normotensive Patients with Type 2 Diabetes Mellitus: A Two- and Three-dimensional Speckle Tracking Study

      Marijana Tadic, Sanja Ilic, Cesare Cuspidi, Biljana Stojcevski, Branislava Ivanovic, Ljiljana Bukarica, Ljilja Jozika and Vera Celic

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12790

  13. Case Reports

    1. Collagenous Fibroma of the Right Coronary Cusp: A Case Report and Literature Review

      Yanbo Zhu, Xiuhong Zhang, Xin Guan and Lianqun Wang

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12789


      Collagenous fibroma (desmoplastic fibroblastoma) is a rare benign tumor reported recently. This is the first description of collagenous fibroma in human heart.

  14. Image Sections

    1. A Residual Intramyocardial Cystic Dissection after Cardiac Fibroma Resection

      Wenjuan Bai, Lijun Zeng and Li Rao

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12798


      The article discusses a residual intramyocardial cystic dissection as a complication after cardiac fibroma resection. It indicates the usefulness of echocardiography, especially three-dimensional echocardiography, to get a complete picture of the entire lesion.

  15. Original Investigations

    1. Tricuspid Annular Plane Systolic Excursion Is Reduced in Infants with Pulmonary Hypertension

      Dala Zakaria, Ritu Sachdeva, Jeffrey M. Gossett, Xinyu Tang and Matthew J. O'Connor

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12797

  16. Review Articles

    1. Foreign Bodies in the Heart

      Marina Leitman and Zvi Vered

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12795

  17. Original Investigations

    1. Application of Intravascular Ultrasound in the Emergency Diagnosis and Treatment of Patients with ST-Segment Elevation Myocardial Infarction

      Hong-Xia Wang, Ping-Shuan Dong, Zhi-Juan Li, Hong-Lei Wang, Ke Wang and Xiang-Yong Liu

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12794

  18. Case Reports

    1. An Interesting Case of Tricuspid Aortic Valve with a Quadricuspid Function

      Elena Tessitore, Hajo Müller, Chris Nadege Nganou-Gnindjio, Philippe Grisel and Lučka Šekoranja

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12793


      Quadricuspid aortic valve (QAV) is a rare congenital heart defect, often related to severe aortic regurgitation, and usually detected by echocardiography or at the time of aortic valve surgery. We report a case of an interesting and extremely rare variant of “false” QAV, detected preoperatively by transthoracic and transesophageal echocardiography, in a severely symptomatic patient, admitted to our hospital for dyspnea. Three leaflets of aortic valve appeared quadricuspid, because the left coronary cusp was divided into two parts, as confirmed by MRI and pathology.

  19. Image Sections

    1. Tuberculous Pericarditis Mimicking a Pericardial Tumor

      Roman Komorovsky, Ulyana Slaba and Svitlana Smiyan

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12792


      The image and the clinical message focus on an unusual presentation of tuberculous pericardial involvement appearing as a loculated organized pericardial effusion mimicking a pericardial tumor. Antituberculous combination therapy resulted in complete resolution of the pericardial mass. To the best of our knowledge, such presentation of tuberculous pericarditis has not been previously reported.

  20. Original Investigations

    1. Right Ventricular Global Longitudinal Strain Is an Independent Predictor of Right Ventricular Function: A Multimodality Study of Cardiac Magnetic Resonance Imaging, Real Time Three-Dimensional Echocardiography and Speckle Tracking Echocardiography

      Ken J. Lu, Janet X. C. Chen, Konstantinos Profitis, Leighton G. Kearney, Dimuth DeSilva, Gerard Smith, Michelle Ord, Susan Harberts, Paul Calafiore, Elizabeth Jones and Piyush M. Srivastava

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12783

  21. Book Reviews

    1. Complex Cases in Echocardiography

      Ramdas G. Pai

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12784

  22. Original Investigations

    1. Coronary Flow Velocity Reserve in Patients with Ascending Aorta Aneurysm

      Ahmet Oytun Baykan, Gülhan Yüksel Kalkan, Mustafa Gür, Hakan Uçar, Armağan Acele, Taner Şeker, Ömer Şen, Onur Kaypakli, Hazar Harbalioğlu and Murat Çayli

      Article first published online: 7 OCT 2014 | DOI: 10.1111/echo.12782

    2. Pulmonary Pulse Transit Time: A Novel Echocardiographic Indicator of Hemodynamic and Vascular Alterations in Pulmonary Hypertension and Pulmonary Fibrosis

      Thomas Wibmer, Stefan Rüdiger, Dominik Scharnbeck, Michael Radermacher, Sinisa Markovic, Kathrin M. Stoiber, Wolfgang Rottbauer and Christian Schumann

      Article first published online: 29 SEP 2014 | DOI: 10.1111/echo.12772

  23. UAB

    1. The Advantages of Live/Real Time Three-Dimensional Transesophageal Echocardiography in the Assessment of Tricuspid Valve Infective Endocarditis

      Aylin Sungur, Ming C. Hsiung, Luis D. Meggo Quiroz, Tuğba Kemaloğlu Öz, Ayman Haj Asaad, Deepak Joshi, Cevdet Dönmez, Tolga S. Güvenç and Navin C. Nanda

      Article first published online: 25 SEP 2014 | DOI: 10.1111/echo.12785

  24. Original Investigations

    1. Reliability of Doppler-Based Measurement of Pulmonary Vascular Resistance in Congenital Heart Disease with Left-to-Right Shunt Lesions

      Srinivas Bhyravavajhala, Vanajakshamma Velam, Nishanth V. Polapragada, Pranav Pallempati, Tammi Raju Iragavarapu, Amar Narayan Patnaik and Seshagiri Rao Damera

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12779

    2. Evaluation of Global Function of the Heart in Scleroderma Patients

      Demet Menekse Gerede, Sibel Turhan, Refika Hural, Aynur Acıbuca, Orhan Kucuksahin, Ozgur Ulas Ozcan, Huseyin Goksuluk, Veysel Kutay Vurgun and Cetin Erol

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12774

    3. Left Ventricular Diastolic Dysfunction in Type I Gaucher Disease: An Echo Doppler Study

      Francesco Lo Iudice, Antonio Barbato, Riccardo Muscariello, Carlo Di Nardo, Francesco de Stefano, Michelina Sibilio, Pasquale Strazzullo, Giovanni de Simone and Maurizio Galderisi

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12759

  25. Doppler Hemodynamics

    1. Respiratory Hemodynamics in the Hepatic Veins—Abnormal Patterns

      Bahaa M. Fadel, Ahmad Alkalbani, Aysha Husain, Ziad Dahdouh and Giovanni Di Salvo

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12757

  26. Original Investigations

    1. Left Atrial Volume Index as a Predictor for Persistent Left Ventricular Dysfunction after Aortic Valve Surgery in Patients with Chronic Aortic Regurgitation: The Role of Early Postoperative Echocardiography

      In-Jeong Cho, Hyuk-Jae Chang, Geu-Ru Hong, Ran Heo, Ji Min Sung, Sang-Eun Lee, Byung-Chul Chang, Chi Young Shim, Jong-Won Ha and Namsik Chung

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12756

  27. Image Sections

    1. A Thrombotic Right Sinus of Valsalva Aneurysm Causing Acute Myocardial Infarction and Ischemic Stroke

      Nihat Polat, Abdulkadir Yildiz, Murat Yuksel, Halit Acet and Sait Alan

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12755


      Aneurysm of the sinus of Valsalva (ASV) is an uncommon condition which may be congential or acquired. Here, we describe a case of ASV thrombosis presented with both acute myocardial infarction and acute stroke.

  28. Case Reports

    1. Diagnosis of Pentacuspid Aortic Valve with Severe Regurgitation Using Three-Dimensional Transesophageal Echocardiography

      Sinem Ozyilmaz, Ozgur Akgul, Alper Guzeltas and Isa Ozyilmaz

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12752


      We describe a 48-year-old female patient with a pentacuspid aortic valve and severe aortic regurgitation that was diagnosed using three-dimensional transesophageal echocardiography.

  29. Image Sections

    1. Role of Three-Dimensional Transesophageal Echocardiography in Diagnosis of Coronary Anomalies

      Alexis Theron, Alexis Jacquier, Eleonore Ravis, Thibault Ronchard, Jean-Yves Gaubert, Dominique Grisoli, Vlad Gariboldi and Frederic Collart

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12751


      A 16-year-old man was referred to our institution after a recovered sudden cardiac death supported with extracorporeal membrane oxygenation. A three-dimensional transesophageal echocardiography (3DTEE) revealed a left anterior descending coronary artery arising from the right coronary sinus with a course between the aorta and the pulmonary artery. After extracorporeal membrane oxygenation weaning, a multidetector computed tomography coronary angiogram scan confirmed the 3DTEE findings. Here, we suggested that 3DTEE can provide a reliable coronary anatomic assessment in some emergency cases when it is not possible to shift the patient out of the ICU.

  30. Case Reports

    1. Fibrous Cyst of the Chordae Tendineae of the Mitral Valve: Echocardiographic Appearance and Literature Review

      Yan-Bo Zhu, Xiu-Hong Zhang, Lian-Qun Wang and Xin Guan

      Article first published online: 24 SEP 2014 | DOI: 10.1111/echo.12750


      Mitral chordae fibrous cyst is defined as a fibrous cyst arising from the chordae tendineae of the mitral valve. It is extremely rare and its etiology is not clear. Only one case has been reported in the past years. We present a case of mitral chordae fibrous cyst.

  31. Original Investigations

    1. Three-Dimensional Transesophageal Echocardiographic Study of Aortic-Mitral Valve Coupling after Coronary Artery Bypass Grafting

      Shao-Hui Qu, Ming-Chon Hsiung, Xiao-Ping Leng, Jeng Wei, Guo-Qing Du, Helene Houle, Wei-Hsian Yin and Jia-Wei Tian

      Article first published online: 23 SEP 2014 | DOI: 10.1111/echo.12748

  32. Image Sections

    1. Unusual Myocardial Late Gadolinium Enhancement in Isolated Noncompaction Cardiomyopathy

      Sherif Moustafa, David J. Patton, Mansour Al Shanawani, Michael S. Connelly, Nanette Alvarez, Timothy Prieur and Farouk Mookadam

      Article first published online: 22 SEP 2014 | DOI: 10.1111/echo.12778


      Noncompaction cardiomyopathy is characterized by prominent ventricular trabeculations and deep intertrabecular recesses with high risk of mortality and morbidity secondary to heart failure, thromboembolic events, and malignant arrhythmias. We herein report a 19-year-old man with isolated noncompaction cardiomyopathy in which the echocardiography and cardiac magnetic resonance were very useful in decision making regarding his optimal management.

  33. ViewPoints

  34. Doppler Hemodynamics

    1. Spectral Doppler of the Hepatic Veins in Tricuspid Valve Disease

      Bahaa M. Fadel, Khaled Almulla, Aysha Husain, Ziad Dahdouh, Giovanni Di Salvo and Dania Mohty

      Article first published online: 22 SEP 2014 | DOI: 10.1111/echo.12773

  35. Special Issue: Imaging the Right Heart

    1. Editorial

      Imaging the Right Heart: A Challenging Road Map

      Eduardo Bossone, Navin C. Nanda and Robert Naeije

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12563

    2. Right Heart and Pulmonary Vessels Structure and Function

      Michele D'Alto, Giancarlo Scognamiglio, Kostantinos Dimopoulos, Eduardo Bossone, Dario Vizza, Emanuele Romeo, Anton Vonk-Noordergraaf, Sean Gaine, Andrew Peacock and Robert Naeije

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12227

    3. Right Heart Structural and Functional Remodeling in Athletes

      Antonello D'Andrea, Andrè La Gerche, Enrica Golia, Arco J. Teske, Eduardo Bossone, Maria Giovanna Russo, Raffaele Calabrò and Aaron L. Baggish

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12226

    4. Pulmonary Arterial Hypertension: The Key Role of Echocardiography

      Michele D'Alto, Emanuele Romeo, Paola Argiento, Giovanni Di Salvo, Roberto Badagliacca, Anna P. Cirillo, Harald Kaemmerer, Eduardo Bossone and Robert Naeije

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12283

    5. Imaging of the Right Heart—CT and CMR

      Jonathan Kochav, Lauren Simprini and Jonathan W. Weinsaft

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12212

    6. Nuclear Assessment of Right Ventricle

      Paola Gargiulo, Alberto Cuocolo, Santo Dellegrottaglie, Maria Prastaro, Gianluigi Savarese, Roberta Assante, Emilia Zampella, Stefania Paolillo, Oriana Scala, Donatella Ruggiero, Fabio Marsico and Pasquale Perrone Filardi

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12180

    7. Right Ventricular Cardiomyopathies: A Multidisciplinary Approach to Diagnosis

      Giuseppe Limongelli, Alessandra Rea, Daniele Masarone, M. Paola Francalanci, Aris Anastasakis, Raffaele Calabro', Russo Maria Giovanna, Eduardo Bossone, Perry Mark Elliott and Giuseppe Pacileo

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12399

    8. Review Articles

      Echocardiography and Heart Failure: A Glimpse of the Right Heart

      Adam Pleister, Rami Kahwash, Garrie Haas, Stefano Ghio, Antonio Cittadini and Ragavendra R Baliga

      Article first published online: 19 SEP 2014 | DOI: 10.1111/echo.12678

  36. Original Investigations

    1. Assessment of Quality of Fetal Heart Views by 3D/4D Ultrasonography Using Spatio-Temporal Image Correlation in the Second and Third Trimesters of Pregnancy

      Luciane Alves Rocha, Liliam Cristine Rolo, Fernanda Silveira Bello Barros, Luciano Marcondes Machado Nardozza, Antonio Fernandes Moron and Edward Araujo Júnior

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12743

    2. Association of Left Atrial Booster-Pump Function with Heart Failure Symptoms in Patients with Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction

      Junichi Imanishi, Hidekazu Tanaka, Takuma Sawa, Yoshiki Motoji, Tatsuya Miyoshi, Yasuhide Mochizuki, Yuko Fukuda, Kazuhiro Tatsumi, Kensuke Matsumoto, Yutaka Okita and Ken-ichi Hirata

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12733

  37. Original Investigation

  38. Case Reports

    1. Real Time Three-Dimensional Transesophageal Echocardiography Demonstration of Membranous Septal Aneurysm Causing Severe Right Ventricular Outflow Tract Obstruction

      Saktheeswaran K. Mahesh, Senthil Kumar, Santhosh Satheesh and Balachander Jayaraman

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12739


      In addition to infundibular muscular hypertrophy and anomalous muscle bundles in the right ventricular body, large membranous septal aneurysms (MSA), sinus of Valsalva aneurysms, and aneurysms derived from the embryonic venous valve protruding through the tricuspid valve can cause right ventricular outflow obstruction in a patient with ventricular septal defect. Here we describe an adult with a small perimembranous ventricular septal defect complicated by a large MSA causing severe right ventricular outflow obstruction evaluated with real time three-dimensional transesophageal echocardiography.

    2. Real Time Three-Dimensional Transesophageal Echocardiography Guided Coronary Sinus Cannulation during CARILLON Mitral Annuloplasty Device Therapy for a Patient with Chronic Severe Mitral Regurgitation

      Hani M. Mahmoud, Mohammed A. Al-Ghamdi and Abdullah E. Ghabashi

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12745


      The coronary sinus (CS) has become a clinically important structure especially through its role in providing access for different cardiac procedures. Fluoroscopy with or without two dimensional transesophageal echocardiography (2DTEE) is the widely used method for guidance. A 78-year-old female patient was undergoing percutaneous CARILLON mitral annuloplasty device therapy for chronic severe symptomatic mitral regurgitation. After insertion of the coronary sinus catheter through the right internal jugular vein, multiple trials for coronary sinus cannulation guided by fluoroscopy and 2DTEE were unsuccessful. So, real time three-dimensional zoom mode was used to get the anatomically oriented en face view of the interatrial septum from the right atrial perspective. The CS ostium was identified then the catheter was reintroduced through the SVC into the right atrium then easily navigated to cannulate the coronary sinus ostium.

    3. Right Ventricular Mass: Intracardiac Ectopic Thyroid Tissue: A Case Report

      Murat Bulent Rabus, Nertila Poçi, Fatih Yılmaz, Onur Yerlikhan, Tugba Aktemur, Akin Arslan, Selcuk Ozturk, Ibrahim Oztek and Mehmet Balkanay

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12741


      Ectopic thyroid tissue is a result of abnormal migration of thyroid tissue during the embryonic state. Most of these rare cases, almost 90% of them, are located in the base of the tongue and a minority of them are located anteriorly near the hyoid bone area. We report the case of a young patient with an intracardiac mass first diagnosed with three-dimensional echocardiography and after successfully being treated surgically.

  39. Image Sections

    1. Three-Dimensional Image of a Baffle Leak in a Patient with a Mustard Operation

      Clifford L. Cua, Kevin Kollins, Sharon Roble and Ralf J. Holzer

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12736


      Baffle leaks are one type of complication following the Mustard operation for transposition of the great arteries. In this case, a 27-year-old male status post–Mustard operation scheduled for a pacemaker placement was noted to have a positive agitated saline contrast study via transesophageal echocardiography. The baffle leak could not be well defined despite extensive two-dimensional imaging. With three-dimensional imaging, the superior and posterior located baffle leak was clearly imaged. Three-dimensional echocardiography allows unparalleled imaging in identifying the location of baffle leaks in patients with complex intracardiac procedures such as the Mustard operation.

  40. Original Investigations

    1. Best Method for Right Atrial Volume Assessment by Two-Dimensional Echocardiography: Validation with Magnetic Resonance Imaging

      Mahasti Ebtia, Darra Murphy, Kenneth Gin, Pui K. Lee, John Jue, Parvathy Nair, John Mayo, Marion E. Barnes, Darby J. S. Thompson and Teresa S. M. Tsang

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12735

  41. Image Sections

    1. Real Time Three-Dimensional Transthoracic Echocardiography in Assessment of Stented Coarctation of Aorta: A Case-Based Presentation

      Ahmed Almomani, Shreyas Modi and Masood Ahmad

      Article first published online: 18 SEP 2014 | DOI: 10.1111/echo.12734


      The treatment for aortic coarctation has evolved from surgical repair to percutaneous endovascular balloon angioplasty and stenting. Imaging techniques are playing an important role in assessment of these patients. We present a case in whom an accurate assessment of the patency of the stent and the adequacy of flow were obtained by real time three-dimensional echocardiography. Compared to other imaging modalities, echocardiography is inexpensive. It also avoids the risks of radiation and contrast associated with computed tomographic (CT) angiography, and the potential artifacts that may occur with cardiac magnetic resonance (MR). Real time three-dimensional echocardiography from a transthoracic approach appears promising in evaluating morphology and functionality of the stented coarctation of the descending aorta.

  42. Case Reports

    1. Three-Dimensional Echocardiography Guided Closure of Complex Multiple Atrial Septal Defects

      Yasufumi Kijima, Teiji Akagi, Koji Nakagawa, Yoichi Takaya, Hiroki Oe and Hiroshi Ito

      Article first published online: 16 SEP 2014 | DOI: 10.1111/echo.12731


      Transcatheter closure of complex multiple atrial septal defects (ASDs) remains a challenge. We describe our clinical experience with staged device deployment in a patient with multiple ASDs using four Amplatzer septal occluder devices. Three-dimensional transesophageal echocardiography imaging contributed not only to the therapeutic guidance of successful device deployment but also to the decision making for the staged device delivery approach in a case of morphologically complex multiple ASDs.

  43. Editorial

  44. Doppler Hemodynamics

    1. Respiratory Hemodynamics in the Hepatic Veins—Normal Pattern

      Bahaa M. Fadel, Ahmad Alkalbani, Aysha Husain, Ziad Dahdouh and Giovanno Di Salvo

      Article first published online: 15 SEP 2014 | DOI: 10.1111/echo.12744

  45. Original Investigations

    1. Biventricular Response of the Heart to Endurance Exercise Training in Previously Untrained Subjects

      Aleksandra Rojek, Dariusz Bialy, Monika Przewlocka-Kosmala, Marta Negrusz-Kawecka, Andrzej Mysiak and Wojciech Kosmala

      Article first published online: 8 SEP 2014 | DOI: 10.1111/echo.12737

  46. Image Sections

    1. Primary Intimal (Spindle Cell) Sarcoma of the Left Atrium

      Bo Fu, Hui Yu and Jian Yang

      Article first published online: 5 SEP 2014 | DOI: 10.1111/echo.12777


      A previously healthy 50-year-old man presented to our hospital with a history of progressive shortness of breath and diminished exercise tolerance for 3 months. A transthoracic echocardiogram was interpreted as showing a left atrial mass that was mobile and protruding into the left ventricle and noted that it was “like a myxoma, though its attachment was not visualized.” He was taken to the operating room with the initial diagnosis of left atrial myxoma, but upon surgical inspection of the left atrium, it was noted that the appearance of the tumor was more suggestive of malignancy. Pathologic examination revealed sheets of high-grade densely packed spindle cells replacing and infiltrating into the atrial wall.

  47. ECHO ROUNDS Section Editor: Edmund Kenneth Kerut, M. D.

    1. The Role of Jet Eccentricity in Generating Disproportionately Elevated Transaortic Pressure Gradients in Patients with Aortic Stenosis

      Amr E. Abbas, Laura M. Franey, Steven Lester, Gilbert Raff, Michael J. Gallagher, George Hanzel, Robert D. Safian and Philippe Pibarot

      Article first published online: 20 AUG 2014 | DOI: 10.1111/echo.12712

  48. Original Investigations

    1. Cardiac Strain during Upright Cycle Ergometry in Adolescent Males

      Viswanath B. Unnithan, Thomas Rowland, Martin R. Lindley, Denise M. Roche, Max Garrard and Piers Barker

      Article first published online: 12 AUG 2014 | DOI: 10.1111/echo.12708

    2. Different Implication of Elevated B-Type Natriuretic Peptide Level in Patients with Heart Failure with Preserved Ejection Fraction and in Those with Reduced Ejection Fraction

      Takako Ishigaki, Takashi Yoshida, Hiromi Izumi, Yoshihisa Fujisawa, Shoko Shimizu, Kasumi Masuda, Toshihiko Asanuma, Hidetoshi Okabe and Satoshi Nakatani

      Article first published online: 12 AUG 2014 | DOI: 10.1111/echo.12707

    3. Assessment of Atrial Electromechanical Delay and Left Atrial Mechanical Functions in Patients with Psoriasis Vulgaris

      Gökhan Aksan, Gökay Nar, Korhan Soylu, Sinan İnci, Serkan Yuksel, Hande Serra Ocal, Esra Pancar Yuksel and Okan Gulel

      Article first published online: 12 AUG 2014 | DOI: 10.1111/echo.12706

  49. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Bad Company: Supracristal VSD Presenting with Ruptured Sinus of Valsalva Aneurysm. A Case Presentation with Echocardiographic Depiction and an Analysis of Contemporary Literature

      Gregory R. Hartlage, Michelle A. Consolini, Maria A. Pernetz, B. Robinson Williams III, Stephen D. Clements, Edward P. Chen and S. Tanveer Rab

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12718

  50. Original Investigations

    1. Effects of Frame Rate on Two-Dimensional Speckle Tracking–Derived Measurements of Myocardial Deformation in Premature Infants

      Aura A. Sanchez, Philip T. Levy, Timothy J. Sekarski, Aaron Hamvas, Mark R. Holland and Gautam K. Singh

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12716

    2. Utility of Intracardiac Echocardiography for Catheter Ablation of Complex Cardiac Arrhythmias in a Medium-Volume Training Center

      David Filgueiras-Rama, Fernando de Torres-Alba, Sergio Castrejón-Castrejón, Alejandro Estrada, Jorge Figueroa, Óscar Salvador-Montañés, Teresa López, Mar Moreno-Yanguela, José L. López Sendón and José L. Merino

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12714

  51. Case Reports

    1. Three-Dimensional Echocardiography-Based Prediction of Posterior Leaflet Resection

      Yonghoon Rim, Ahnryul Choi, Susan T. Laing, David D. McPherson and Hyunggun Kim

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12717


      Clinical long-term outcomes have shown that partial leaflet resection followed by ring annuloplasty is a reliable and reproducible surgical repair technique for treatment of mitral valve (MV) leaflet prolapse. We report a 61-year-old male for three-dimensional transesophageal echocardiography (3DTEE)-based virtual posterior leaflet resection and ring annuloplasty. Severe mitral regurgitation was found and computational evaluation demonstrated substantial leaflet malcoaptation and high stress concentration. Following virtual resection and ring annuloplasty, posterior leaflet prolapse markedly decreased, sufficient leaflet coaptation was restored, and high stress concentration disappeared. Virtual MV repair strategies using 3DTEE have the potential to help optimize MV repair.

  52. Doppler Hemodynamics

    1. Spectral Doppler Interrogation of the Patent Foramen Ovale–A Window to Left Heart Hemodynamics

      Bahaa M. Fadel, Aysha Husain, Hatem Bakarman, Ziad Dahdouh, Giovanni Di Salvo and Dania Mohty

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12723

  53. Original Investigations

    1. Two-Dimensional Speckle Tracking Echocardiography for the Prediction of Reversible Myocardial Dysfunction after Acute Myocardial Infarction: Comparison with Magnetic Resonance Imaging

      Makoto Orii, Kumiko Hirata, Takashi Tanimoto, Yasutsugu Shiono, Kunihiro Shimamura, Kohei Ishibashi, Takashi Yamano, Yasushi Ino, Hironori Kitabata, Tomoyuki Yamaguchi, Takashi Kubo, Toshio Imanishi and Takashi Akasaka

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12726

  54. Case Reports

    1. Evolutionary Change Mimicking Apical Hypertrophic Cardiomyopathy in a Patient with Takotsubo Cardiomyopathy

      Hui-Jeong Hwang, Hyae-Min Lee, In-Ho Yang, Dong-Hee Kim, Jong-Kyu Byun and Il Suk Sohn

      Article first published online: 11 AUG 2014 | DOI: 10.1111/echo.12722


      In this report, we introduce a case of thickening of the involved left ventricular apical segment on echocardiography and deep T wave inversions in precordial leads on electrocardiography transiently seen in the course of recovery from biventricular Takotsubo cardiomyopathy, mimicking apical hypertrophic cardiomyopathy. This result suggests that the echocardiographic finding of transient myocardial edema can be identified by cardiac magnetic resonance imaging in Takotsubo cardiomyopathy. Additionally it persisted a few weeks after full functional recovery. We believe that this case will contribute in part towards clarifying the pathophysiology of Takotsubo cardiomyopathy.

  55. Review Articles

  56. Original Investigations

    1. Influence of Pulmonary Vascular Reserve on Exercise-Induced Pulmonary Hypertension in Patients with Systemic Sclerosis

      Kengo Suzuki, Masaki Izumo, Ryo Kamijima, Kei Mizukoshi, Manabu Takai, Keisuke Kida, Kihei Yoneyama, Sachihiko Nobuoka, Hidehiro Yamada and Yoshihiro J. Akashi

      Article first published online: 8 AUG 2014 | DOI: 10.1111/echo.12690

  57. Image Sections

    1. A Case of Carcinoid Heart Disease with Desaturation and No Liver Metastases

      Annelies Requilé, Alexander Van De Bruaene, Veerle Reenaers and Paul Dendale

      Article first published online: 5 AUG 2014 | DOI: 10.1111/echo.12713


      In 95% of cases of carcinoid heart disease, the primary tumor is located in the gastrointestinal tract and hepatic inactivation of serotonin prevent symptoms from occurring until liver metastases are present. Ovarian carcinoid tumors are an unusual cause of carcinoid heart disease in the absence of liver metastases. Rarely, carcinoid heart disease is associated with desaturation due to right-to-left shunting through a patent foramen ovale. We present the case of a 64-year-old female with carcinoid heart disease without liver metastases and hypoxemia due to right-to-left shunting.

  58. Original Investigations

    1. Thromboembolic Risk in Atrial Fibrillation: Association between Left Atrium Mechanics and Risk Scores. A Study Based on 3D Wall-Motion Tracking Technology

      Fabián Islas, Carmen Olmos, Catarina Vieira, José A. De Agustín, Pedro Marcos-Alberca, Adriana Saltijeral, Carlos Almería, José L. Rodrigo, Miguel A. García Fernández, Carlos Macaya and Leopoldo Pérez de Isla

      Article first published online: 5 AUG 2014 | DOI: 10.1111/echo.12711

  59. Doppler Hemodynamics

    1. Spectral Doppler of the Hepatic Veins in Pulmonary Hypertension

      Bahaa M. Fadel, Aysha Husain, Nader Alassoussi, Ziad Dahdouh and Dania Mohty

      Article first published online: 5 AUG 2014 | DOI: 10.1111/echo.12710

  60. Original Investigations

    1. Footprints of Cardiac Mechanical Activity as Expressed in Lung Doppler Signals

      Yoram Palti, Rachel Schatzberger, Majd Zreik, Emma Solter and Itzhak Kronzon

      Article first published online: 5 AUG 2014 | DOI: 10.1111/echo.12689

  61. Case Reports

    1. Lateral Left Ventricular Wall Rupture Following Acute Myocardial Infarction: Pathophysiological Interpretation by Multimodality Imaging Approach

      Gustavo Avegliano, Diego Conde, María Isabel González Ruiz, Paola Kuschnir, Agustina Sciancalepore, Florencia Castro and Ricardo Ronderos

      Article first published online: 3 AUG 2014 | DOI: 10.1111/echo.12727


      Lateral left ventricular wall rupture (LVWR) is a rare complication following acute myocardial infarction (AMI) less than 1%. After cardiogenic shock, LVWR constitutes the most common cause of in-hospital death in AMI patients. Around 40% of all LVWR occurred during the first 24 hours and 85% within the first week. In the present case, 76 hours following the intervention, LVWR was observed likely due to a small infarction at the lateral left ventricular wall possibly due to the marginal lesion. Our patient refused surgery and was followed clinically. Eighteen months later, real time three-dimensional echocardiography showed a pseudoaneurysm.

  62. Original Investigations

    1. Feasibility of Perflutren Microsphere Contrast Transthoracic Echocardiography in the Visualization of Ventricular Endocardium during Venovenous Extracorporeal Membrane Oxygenation in a Validated Ovine Model

      David G. Platts, Sara Diab, Kimble R. Dunster, Kiran Shekar, Darryl J. Burstow, Beatrice Sim, Matthew Tunbridge, Charles McDonald, Saul Chemonges, Jonathan Chan and John F. Fraser

      Article first published online: 24 JUL 2014 | DOI: 10.1111/echo.12695

    2. Assessment of Image Quality in Real Time Three-Dimensional Dobutamine Stress Echocardiography: An Integrated 2D/3D Approach

      Amer M. Johri, David W. Chitty, Lanqi Hua, Gergana Marincheva and Michael H. Picard

      Article first published online: 24 JUL 2014 | DOI: 10.1111/echo.12692

    3. Two-Dimensional Strain and Strain Rate Imaging of the Left Atrium and Left Ventricle in Adult Patients with Atrial Septal Defects before and after the Later Stage of Percutaneous Device Closure

      Sinem Cakal, Elif Eroglu, Onur Baydar, Beytullah Cakal, Mehmet Vefik Yazicioglu, Mustafa Bulut, Cihan Dundar, Kursat Tigen, Birol Ozkan, Goksel Acar, Anil Avci and Ali Metin Esen

      Article first published online: 24 JUL 2014 | DOI: 10.1111/echo.12693

    4. Changes in Speckle Tracking Echocardiography Measures of Ventricular Function after Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonary Position

      Shahryar M. Chowdhury, Ziyad M. Hijazi, John F. Rhodes, Saibal Kar, Raj Makkar, Michael Mullen, Qi-Ling Cao, Lazar Mandinov, Jason Buckley, Nicholas P. Pietris and Girish S. Shirali

      Article first published online: 22 JUL 2014 | DOI: 10.1111/echo.12700

    5. Prognostic Value of Total Atrial Conduction Time Measured with Tissue Doppler Imaging to Predict the Maintenance of Sinus Rhythm after External Electrical Cardioversion of Persistent Atrial Fibrillation

      Stefano Maffè, Paola Paffoni, Pierfranco Dellavesa, Lorenzo Cucchi, Franco Zenone, Luca Bergamasco, Anna Maria Paino, Nicolò Franchetti Pardo, Fabiana Signorotti, Lara Baduena and Umberto Parravicini

      Article first published online: 22 JUL 2014 | DOI: 10.1111/echo.12702

    6. Impact of Energy Loss Index and Valvuloarterial Impedance in Patients with Aortic Stenosis Using Three-Dimensional Echocardiography

      Takeji Saitoh, Jun Tanaka, Azusa Furugen, Kenji Harada, Masaki Izumo, Yoko Fukuoka and Takahiro Shiota

      Article first published online: 22 JUL 2014 | DOI: 10.1111/echo.12705

    7. The Figure-of-Eight Artifact in the Echocardiographic Assessment of Percutaneous Disc Occluders: Impact of Imaging Depth and Device Type

      Philippe B. Bertrand, Lars Grieten, Christophe J.P. Smeets, Frederik H. Verbrugge, Wilfried Mullens, Mathias Vrolix, Maximo Rivero-Ayerza, David Verhaert and Pieter M. Vandervoort

      Article first published online: 22 JUL 2014 | DOI: 10.1111/echo.12685

    8. Two-Dimensional Measurement of Tricuspid Annular Plane Systolic Excursion in Children: Can It Substitute for an M-Mode Assessment?

      Muhammad Yasir Qureshi, Benjamin W. Eidem, Chelsea L. Reece and Patrick W. O'Leary

      Article first published online: 22 JUL 2014 | DOI: 10.1111/echo.12687

    9. Normal Pediatric Data for Isovolumic Acceleration at the Lateral Tricuspid Valve Annulus—A Heart Rate – Dependent Measure of Right Ventricular Contractility

      Constance G. Weismann, Michaela C. Bamdad, Sharon Abraham, Stephen Ghiroli, James Dziura and William E. Hellenbrand

      Article first published online: 5 JUL 2014 | DOI: 10.1111/echo.12681

    10. The Effect of Age on Right Ventricular Diastolic Function in Healthy Subjects Undergoing Treadmill Exercise Test

      Murat Celik, Emre Yalcinkaya, Uygar Cagdas Yuksel, Yalcin Gokoglan, Baris Bugan, Hasan Kutsi Kabul and Cem Barcin

      Article first published online: 5 JUL 2014 | DOI: 10.1111/echo.12676

    11. Aortic Valve Stenosis Planimetry by Means of Three-Dimensional Transesophageal Echocardiography in the Real Clinical Setting: Feasibility, Reliability and Systematic Deviations

      Daniel Saura, Gonzalo de la Morena, Pedro J. Flores-Blanco, María J. Oliva, Luis Caballero, Josefa González-Carrillo, María D. Espinosa, María López-Ruiz, Miguel García-Navarro and Mariano Valdés

      Article first published online: 5 JUL 2014 | DOI: 10.1111/echo.12675

    12. Effect of Remote Ischemic Postconditioning on Left Ventricular Mechanics

      Alper Bugra Nacar, Selim Topcu, Mustafa Kurt, Ibrahim Halil Tanboga, Mehmet Fatih Karakaş, Eyup Buyukkaya, Enbiya Aksakal, Nihat Sen, Adnan Burak Akcay and Emine Bilen

      Article first published online: 5 JUL 2014 | DOI: 10.1111/echo.12677

    13. Prevalence and Long-Term Prognosis of Patients with Complete Bundle Branch Block (Right or Left Bundle Branch) with Normal Left Ventricular Ejection Fraction Referred for Stress Echocardiography

      Azhar A. Supariwala, Jose Ricardo F. Po, Sameh Mohareb, Farhan Aslam, Firas Kaddaha, Zainab I. Mian, Farhan Chaudhry, Ahmed Otokiti and Farooq A. Chaudhry

      Article first published online: 5 JUL 2014 | DOI: 10.1111/echo.12680

    14. Left Atrial Deformation Predicts Pulmonary Capillary Wedge Pressure in Pediatric Heart Transplant Recipients

      Jay Yeh, Ranjit Aiyagari, Robert J. Gajarski, Mary C. Zamberlan and Jimmy C. Lu

      Article first published online: 5 JUL 2014 | DOI: 10.1111/echo.12679


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