Cover image for Vol. 33 Issue 2

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Navin C. Nanda

Impact Factor: 1.254

ISI Journal Citation Reports © Ranking: 2014: 88/123 (Cardiac & Cardiovascular Systems)

Online ISSN: 1540-8175


  1. 1 - 78
  1. Case Reports

    1. Multiple Coronary Artery Aneurysms of the Right Coronary Artery in Neonate with Pulmonary Atresia with Intact Ventricular Septum

      Carlie Bremen, David N. Campbell, Lorna Browne and Pei-Ni Jone

      Article first published online: 9 FEB 2016 | DOI: 10.1111/echo.13191


      Pulmonary atresia with intact ventricular septum (PA/IVS) with right ventricular dependent coronaries is a rare congenital cardiac anomaly. Coronary artery aneurysms in a neonate with PA/IVS have not been described. We report a case of neonate with pulmonary atresia with intact ventricular septum with giant coronary artery aneurysms.

  2. Original Investigations

    1. Evaluation of Left and Right Atrial Function in Patients with Coronary Slow-Flow Phenomenon Using Two-Dimensional Speckle Tracking Echocardiography

      Yonghuai Wang, Yan Zhang, Chunyan Ma, Zhengyu Guan, Shuang Liu, Weixin Zhang, Yuling Li and Jun Yang

      Article first published online: 9 FEB 2016 | DOI: 10.1111/echo.13197

    2. Clinical Relevance of Left Atrial Strain to Predict Recurrence of Atrial Fibrillation after Catheter Ablation: A Meta-Analysis

      Xin-Xin Ma, Leif-Hendrik Boldt, Yue-Li Zhang, Meng-Ruo Zhu, Bing Hu, Abdul Parwani, Evgeny Belyavskiy, Aravind K. Radha Krishnan, Maximilian Krisper, Clemens Köhncke, Engin Osmanoglou, Martin Kropf, Philipp Lacour, Florian Blaschke, Frank Edelmann, Carsten Tschöpe, Wilhelm Haverkamp, Elisabeth Pieske-Kraigher, Burkert Pieske and Daniel A. Morris

      Article first published online: 9 FEB 2016 | DOI: 10.1111/echo.13184

  3. Case Reports

    1. Coronary Sinus Orifice Atresia Associated with Persistent Left Superior Vena Cava: A Case Report with Literature Review

      Guang Song, Weidong Ren and Yixin Chen

      Article first published online: 9 FEB 2016 | DOI: 10.1111/echo.13194


      Coronary sinus orifice atresia is usually associated with the “enlarged” CS (>12mm) and “small” persistent left superior vena cava (≤5mm).

  4. Review Articles

  5. Original Investigations

    1. Determination of Right Ventricular Volume by Combining Echocardiographic Distance Measurements

      Stina Jorstig, Micael Waldenborg, Mats Lidén, Maciej Wodecki and Per Thunberg

      Article first published online: 3 FEB 2016 | DOI: 10.1111/echo.13173

    2. Intraventricular Isovolumic Relaxation Flow Patterns Studied by Using Vector Flow Mapping

      Haibin Zhang, Xiaofeng Ren, Jin Song, Xinyu Cao, Benna Wang, Ying Liu, Zhiguo Li and Na Ma

      Article first published online: 1 FEB 2016 | DOI: 10.1111/echo.13192

  6. Case Reports

    1. Papillary Muscle Rupture Following Non-ST-Elevation Myocardial Infarction: A Case Report

      Khalil Murad and Emil Missov

      Article first published online: 29 JAN 2016 | DOI: 10.1111/echo.13177


      Papillary muscle rupture is a serious mechanical complication of acute myocardial infarction typically seen within 5–7 days following transmural ST-elevation myocardial infarction. The incidence of papillary muscle rupture has markedly decreased in the modern era due to improved diagnosis and early coronary revascularization of ST-elevation myocardial infarction. As a result, papillary muscle rupture is increasingly seen following non-ST-elevation myocardial infarction where both diagnosis and revascularization can be delayed. In this report, we describe two cases of papillary muscle rupture following delayed presentation of non-ST-elevation myocardial infarction and delayed recognition of papillary muscle rupture.

  7. Original Investigations

    1. 3D Xplane Echocardiographic Technique for Validation of Mitral Leaflet Separation to Assess Severity of Mitral Stenosis

      Rajendra K. Gokhroo, Bhanwar L. Ranwa, Kamal Kishor, Kumari Priti, Ananthraj Avinash, Sajal Gupta and Devendra Bisht

      Article first published online: 29 JAN 2016 | DOI: 10.1111/echo.13183

    2. Assessment of Impact of Weight Loss on Left and Right Ventricular Functions and Value of Tissue Doppler Echocardiography in Obese Patients

      Isa Oner Yuksel, Nihal Akar Bayram, Erkan Koklu, Cagin Mustafa Ureyen, Selcuk Kucukseymen, Sakir Arslan and Engin Bozkurt

      Article first published online: 29 JAN 2016 | DOI: 10.1111/echo.13185

  8. Doppler Hemodynamics

    1. The Echocardiographic “Spike and Dome” – Obstruction It Is But Where?

      Bahaa M. Fadel, Rasha Bazari, Aysha Husain, Ahmed Fathala, Ziad Dahdouh, Dania Mohty and Giovanni Di Salvo

      Article first published online: 28 JAN 2016 | DOI: 10.1111/echo.13179

  9. Image Sections

    1. Misdiagnosis in Hypoplastic Sinus of Valsalva with Localized Aneurysm: A Diagnostic Pitfall in Computed Tomography

      Yu-Ning Hu, Wei-Chuan Tsai, Yi-Shan Tsai and Chwan-Yau Luo

      Article first published online: 28 JAN 2016 | DOI: 10.1111/echo.13180


      A 56-year-old woman was misdiagnosed, based on a coronary computed tomography, with a left main coronary artery aneurysm the referring hospital. Detailed diagnostic modalities—conventional angiography, transesophageal echocar-diography, and electrocardiography-gated cardiac computed tomography—showed the accurate anatomical structure and supported a final diagnosis of a rare case of hypoplastic sinus of Valsalva with a small localized aneurysm.

  10. Case Reports

    1. Thrombus-in-Transit Following Watchman Device Implantation

      Julia Wallenborn, Frank Weidemann, Björn Lengenfelder, Oliver Ritter and Wolfram Voelker

      Article first published online: 27 JAN 2016 | DOI: 10.1111/echo.13172


      Thrombus-in-transit following left atrial appendage (LAA) closure is a rare clinical condition. We describe here an unusual case of a 76-year-old woman with permanent atrial fibrillation and contraindication for oral anticoagulation therapy undergoing LAA closure. Subsequently, she developed pericaridal tamponade and acute pulmonary embolism with visible thrombus-in-transit formation. The patient was successfully treated with pericardiocentesis and temporary anticoagulation therapy.

  11. Original Investigations

    1. Two-Dimensional Speckle Tracking Echocardiography in Heart Transplant Patients: Two-Year Follow-Up of Right and Left Ventricular Function

      Vanessa Moñivas Palomero, Susana Mingo Santos, Josebe Goirigolzarri Artaza, Elena Rodriguez Gonzalez, María Alejandra Restrepo Córdoba, Diego Jiménez Sanchez, Betsaida Rivero Arribas, Inés Garcia Lunar, Cristina D. Mitroi, Ines Sayago Silva, Miguel A. Cavero Gibanel, Manuel Gómez Bueno, Luis A. Alonso Pulpón and Javier Segovia Cubero

      Article first published online: 25 JAN 2016 | DOI: 10.1111/echo.13169

    2. Comparison of Left Ventricular Contractile Abnormalities in Stress-Induced Cardiomyopathy versus Obstructive Coronary Artery Disease Using Two-Dimensional Strain Imaging

      Alexandros Briasoulis, Karolina Marinescu, Marian Mocanu, Assad Sattar, Osama Qaqi, Shaun Cardozo, Anupama Kottam and Luis Afonso

      Article first published online: 21 JAN 2016 | DOI: 10.1111/echo.13178

    3. Is Low Serum Klotho Level Associated with Alterations in Coronary Flow Reserve?

      Nursen Keles, Mustafa Caliskan, Burcu Dogan, Feyza Aksu, Serkan Bulur, Necibe Nur Keles, Osman Kostek, Soe Moe Aung, Banu Isbilen, Kenan Demircioglu, Macit Kalcik and Aytekin Oguz

      Article first published online: 20 JAN 2016 | DOI: 10.1111/echo.13176

  12. Image Sections

    1. Multimodality Diagnosis Approach of Cardiac Aspergillosis

      Soraya El Ghannudi, Alessio Imperiale, Tristan Dégot, Philippe Germain, Annie Trinh, Roxana Petean, Paulette Le Van Quyen, Marie-Pierrette Chenard, Valerie Letscher-Bru, Romain Kessler and Raoul Herbrecht

      Article first published online: 20 JAN 2016 | DOI: 10.1111/echo.13165


      A 56-year-old patient with a history of bilateral lung transplantation for idiopathic interstitial pneumonia not responding to corticosteroids therapy had a good initial postoperative outcome. One month later, subcutaneous nodules appeared and histopathology revealed septate hyphae in the nodules and Aspergillus fumigatus in bronchial lavage. FDG PET/CT and CMR revealed multiple left and right ventricles abscesses consistent with cardiac aspergillosis. The combination of FDG PET/CT and CMR was useful to detect the cardiac localization of systemic aspergillosis, to define the precise morphological details of myocardial lesions and to evaluate the response to treatment.

    2. Tension Pneumohydropericardium: A Heart Under Stress

      Sudarshan Kumar Vijay and Lalit Mohan Joshi

      Article first published online: 17 JAN 2016 | DOI: 10.1111/echo.13175


      The pneumohydropericardium, occurring spontaneously or after pericardiocentesis, is a rare entity. We describe here an unusual case who developed massive pneumohydropericardium after repeated pericardiocentesis due to leakage of the drainage system. The patient was successfully managed with open surgical drainage.

  13. Case Reports

    1. Resolution (and Late Recurrence) of WATCHMAN Device–Related Thrombus Following Treatment with Dabigatran

      Abdul H. Qazi, Alan P. Wimmer, Kenneth C. Huber, George G. Latus and Michael L. Main

      Article first published online: 17 JAN 2016 | DOI: 10.1111/echo.13174


      A 69 year-old woman underwent successful left atrial (LA) appendage closure with a 24 mm WATCHMAN device. A 1.2 cm x 0.8 cm device-related thrombus (DRT) was noted on the LA aspect of the device by transesophageal echocardiography (TEE) at 1 year follow-up. She was prescribed dabigitran 150 mg po BID for 3 months, and remained on aspirin. A subsequent TEE 4 months later revealed complete resolution of the DRT. A final TEE was performed approximately 8 months later and revealed a new DRT. This report demonstrates that (1) WATCHMAN DRT may form relatively late following implantation (2) DRT resolution is possible with dabigatran and (3) late recurrence of DRT is possible, even after treatment to initial resolution with systemic anticoagulation.

  14. Original Investigations

    1. Right Heart Involvement in Patients with Sarcoidosis

      Mita B. Patel, Victor Mor-Avi, Gillian Murtagh, Catherine A. Bonham, Luke J. Laffin, Douglas Kyle Hogarth, Diego Medvedofsky, Roberto M. Lang and Amit R. Patel

      Article first published online: 16 JAN 2016 | DOI: 10.1111/echo.13163

  15. Editorial

  16. Reviews

    1. Development and Implementation of a Quality Improvement Process for Echocardiographic Laboratory Accreditation

      Yvonne E. Gilliland, Carl J. Lavie, Homaa Ahmad, Jose A. Bernal, Michael E. Cash, Homeyar Dinshaw, Richard V. Milani, Sangeeta Shah, Lisa Bienvenu and Christopher J. White

      Article first published online: 12 JAN 2016 | DOI: 10.1111/echo.13129

  17. Image Sections

    1. Multimodality Imaging to Characterize a Metastatic Cardiac Mass

      Bharath Yarlagadda, Swathi Paleti and Senthil Kumar Annamalai

      Article first published online: 11 JAN 2016 | DOI: 10.1111/echo.13167


      A 66-year-old male with a medical history of squamous cell carcinoma of the head and neck with recurrent metastasis and multiple interventions was found to have a lesion in the heart on positron emission tomography scan. Echocardiography showed a thrombuslike 2 × 2 cm mass attached to the right ventricle side of the septum. Contrast-enhanced cardiac magnetic resonance imaging was obtained to better characterize the mass. It showed a metastatic infiltrative tumor in the septum with a large overlying thrombus protruding into right ventricle. Our case demonstrates the utility of multimodality imaging to characterize an unusual cardiac tumor helping guide management.

  18. Case Reports

    1. Periodic Protrusion of Right Coronary Cusp into Left Ventricular Outflow Tract Due to Detachment from the Aortic Annulus Complicated with Infective Endocarditis

      Hanako Tokuda, Mitsushige Murata, Fumiyuki Yashima, Mikihiko Kudo, Hikaru Tsuruta, Kazuma Okamoto, Yuichiro Maekawa, Motoaki Sano, Hiroyuki Fukushima, Hideyuki Shimizu and Keiichi Fukuda

      Article first published online: 11 JAN 2016 | DOI: 10.1111/echo.13157


      In this report, we present a rare case of unusual dislocation of right coronary cusp into left ventricular outflow tract (LVOT) due to infective endocarditis. Three-dimensional echocardiography precisely demonstrated the spatial anatomy of the aortic root, which was confirmed by the surgical operation. The report shows the usefulness of three-dimensional echocardiography in the detection and evaluation of this rare anomaly.

    2. Use of Unique Doppler Flow-Pattern for the Diagnosis of Left Ventricular Diverticulum

      Ahmed M. Shafter, Ashish Mukherjee, Prabhdeep Sethi and Ramdas G. Pai

      Article first published online: 11 JAN 2016 | DOI: 10.1111/echo.13164


      We describe the unique Doppler flow patterns of a muscular type of LV diverticulum which helped us to differentiate it from postinfarct LV pseudoaneurysm.

  19. Original Investigations

    1. Semiautomatic Evaluation of Tricuspid Annular Plane Systolic Excursion from Two Dimensional Echocardiographic Images

      Senthil Ramamurthy, Michael S. Kelleman, Falon McGaughy and Ritu Sachdeva

      Article first published online: 11 JAN 2016 | DOI: 10.1111/echo.13166

  20. Case Reports

    1. Pedunculated Pulmonary Artery Sarcoma Suggested by Transthoracic Echocardiography

      Xiaobing Wang, Weidong Ren and Jun Yang

      Article first published online: 30 DEC 2015 | DOI: 10.1111/echo.13148


      It is usually difficult to distinguish pulmonary artery sarcoma (PAS) from pulmonary thromboembolism. In this case, TTE showed a part of a PAS attached to the main pulmonary artery with a peduncle and had obvious mobility, which suggested the diagnosis of PAS and differentiated it from pulmonary thromboembolism. To our knowledge, this is the first case report of a pedunculated PAS suggested by TTE. This case demonstrates that TTE could reveal the attachment of PAS and may provide useful information for the diagnosis and differential diagnosis of PAS, especially a pedunculated PAS.

  21. Original Investigations

    1. Vitamin D Attenuates Left Atrial Volume Changes in African American Males with Obesity and Prediabetes

      Satish Jacob Chacko, Sunil Pauwaa, Elena Barengolts, Irina Ciubotaru and Mayank M. Kansal

      Article first published online: 29 DEC 2015 | DOI: 10.1111/echo.13159

    2. Instantaneous Decrease in Left Ventricular Afterload during Transcatheter Aortic Valve Implantation Results in Immediate Changes in Left Ventricular Strain

      Amy Swan, Roshan Prakash, Derek P. Chew, Rebecca Perry, Ajay Sinhal, Joseph B. Selvanayagam and Majo X. Joseph

      Article first published online: 17 DEC 2015 | DOI: 10.1111/echo.13153

  22. Case Reports

    1. Pan-Cardiac Cycle Fixed Mitral Valve Opening in an LVAD Patient Presenting with Hemorrhagic Shock

      Andrew J. Yoon, Jina Sohn, Luanda Grazette, Michael W. Fong and Michael E. Bowdish

      Article first published online: 17 DEC 2015 | DOI: 10.1111/echo.13150


      We report on the unusual echocardiographic finding of mitral valve leaflets that remain fixed wide open throughout the cardiac cycle in an LVAD patient experiencing a suction event in the setting of hemorrhagic shock.

    2. Intra-Cavitary Masses: Rare Presentation of a Common Illness in SAARC Nation

      AKM Monwarul Islam, Rakesh Gupta, Abdullah A. S. Majumder and Tapesh K. Paul

      Article first published online: 16 DEC 2015 | DOI: 10.1111/echo.13155


      During preoperative echocardiographic evaluation of a middle-aged woman with pericardial constriction, echogenic masses were found in left ventricle and right atrium. The masses were extracted, and were found tuberculous by histopathology. Combined pharmacological and surgical approach was successful. Endocardial tuberculoma, the rarest form of cardiovascular tuberculosis, can easily be confused with other common causes of intracardiac mass lesions, especially in echocardiography.

  23. Review Articles

  24. Original Investigations

    1. Echocardiographic Diagnosis of Acute Pulmonary Embolism in Patients with McConnell's Sign

      Anuj Mediratta, Karima Addetia, Diego Medvedofsky, Mardi Gomberg-Maitland, Victor Mor-Avi and Roberto M. Lang

      Article first published online: 15 DEC 2015 | DOI: 10.1111/echo.13142

    2. Importance of Relationship between Ductus and Isthmus in Fetal Diagnosis of Coarctation of Aorta

      Benjamin J. Toole, Brian Schlosser, Courtney E. McCracken, Nanci Stauffer, William L. Border and Ritu Sachdeva

      Article first published online: 14 DEC 2015 | DOI: 10.1111/echo.13140

  25. Image Sections

    1. Circumflex Origin from Right Coronary Artery—The Anomaly That Should Not Be Omitted during Echocardiography—”Crossed Aorta” and “Bleb Sign” Presentation after Stents Implantation

      Karina Wierzbowska-Drabik, Jarosław D. Kasprzak, Ewa Mrozowska-Peruga and Jan Z. Peruga

      Article first published online: 14 DEC 2015 | DOI: 10.1111/echo.13141


      Simultaneously with the development of echocardiography its potential in the assessment of coronary arteries increases. We reported previously that the anomalous circumflex (Cx) originating from right coronary artery (RCA) with retroaortic course may be observed in transesophageal examination (TEE) as vessel cross section in the mitroaortic angle—”bleb sign” or visualized in modified apical four-chamber view behind left atrium during transthoracic study (TTE). In present case, we propose novel finding indicating on this anomaly in apical five-chamber view in TTE forming “crossed aorta” sign. Additionally, the presence of stents in Cx enhanced echocardiographic presentation of anomalous artery course.

  26. Original Investigations

    1. Left Ventricular Myocardial Deformation Parameters Are Affected by Coronary Slow Flow Phenomenon: A Study of Speckle Tracking Echocardiography

      Okan Gulel, Murat Akcay, Korhan Soylu, Gokhan Aksan, Serkan Yuksel, Halit Zengin, Murat Meric and Mahmut Sahin

      Article first published online: 14 DEC 2015 | DOI: 10.1111/echo.13146

  27. Case Reports

    1. Double-Orifice Tricuspid Valve: A Case Report and Literature Review

      Mozhdeh Dabirian, Maryam Nabati, Rozita Jalalian and Mojtaba Shokri

      Article first published online: 13 DEC 2015 | DOI: 10.1111/echo.13127


      Duplication of an atrioventricular valve is a rare congenital anomaly that usually involves the mitral rather than the tricuspid valve (TV). We report a rare case of an HIV-seropositive male with a double-orifce TV (DOTV), divided right atrium and Wolff-Parkinson-White syndrome. We summarized the characteristics of the DOTV and reviewed the literature.

    2. Spontaneous Tricuspid Valve Chordal Rupture in Idiopathic Pulmonary Hypertension

      Ana Clara Tude Rodrigues, José E. Afonso, Adriana Cordovil, Claudia Monaco, Rafael Piveta, Rodrigo Cordovil, Claudio H. Fischer, Marcelo Vieira, Edgar Lira-Filho and Samira S. Morhy

      Article first published online: 13 DEC 2015 | DOI: 10.1111/echo.13130


      Rupture of tricuspid valve is unusual, occurring mainly in the setting of blunt trauma or endomyocardial biopsy. Spontaneous tricuspid valve chordal rupture is particularly rare. We report herein a case of a patient with severe pulmo-nary hypertension, on the lung transplantation waiting list, who presented with spontaneous chordal rupture, exacerbation of tricuspid insufficiency and worsening of clinical status. Diagnosis and treatment, along with possible mechanisms for this complication, are discussed.

  28. Original Investigations

    1. Efficacy and Accuracy of Novel Automated Mitral Valve Quantification: Three-Dimensional Transesophageal Echocardiographic Study

      Nobuyuki Kagiyama, Misako Toki, Masahiko Hara, Shuichiro Fukuda, Shingo Aritaka, Tomonori Miki, Minako Ohara, Akihiro Hayashida, Atsushi Hirohata, Keizo Yamamoto and Kiyoshi Yoshida

      Article first published online: 13 DEC 2015 | DOI: 10.1111/echo.13135

    2. The Incremental Value of Magnetic Resonance Imaging for Identification of Apical Pouch in Patients with Apical Variant of Hypertrophic Cardiomyopathy

      Darko Vucicevic, Steven J. Lester, Christopher P. Appleton, Prasad M. Panse, John William Schleifer and Susan Wilansky

      Article first published online: 30 NOV 2015 | DOI: 10.1111/echo.13118

  29. Case Reports

    1. Multimodality Imaging Diagnostic Approach of Systemic-to-Pulmonary Vein Fistulae

      Soraya El Ghannudi, Philippe Germain, Mi-Young Jeung, Christine Jahn, Sandrine Hirschi and Catherine Roy

      Article first published online: 24 NOV 2015 | DOI: 10.1111/echo.13116


      A 26-year-old man with a history of bilateral lung transplantation for pulmonary cystic fibrosis 6 months before was admitted in our institution for acute heart failure. Cardiac magnetic resonance imaging (CMR) showed an increased aortic output, as aortic flow assessed by velocity mapping was twofold the pulmonary flow, an occluded superior vena cava (SVC), and enlarged azygos vein. A systemic-to-pulmonary vein fistula (SAPVF) was suspected. The selective angiography showed numerous fistulae between intercostals, thyro-cervical, internal mammary arteries and pulmonary veins. The thoracic CT performed before the CMR, which was initially considered as normal, showed well these arteriovenous fistulae after 3D MIP reconstruction.

  30. Original Investigations

    1. Coronary Flow Reserve Predicts Longitudinal Myocardial Deformation Capacity in Heart-Transplanted Patients

      Tor Skibsted Clemmensen, Brian Bridal Løgstrup, Hans Eiskjær and Steen Hvitfeldt Poulsen

      Article first published online: 24 NOV 2015 | DOI: 10.1111/echo.13123

    2. Patients with Diabetes and Significant Epicardial Coronary Artery Disease Have Increased Systolic Left Ventricular Apical Rotation and Rotation Rate at Rest

      Ravi Rasalingam, Mark R. Holland, Daniel H. Cooper, Eric Novak, Michael W. Rich, James G. Miller and Julio E. Pérez

      Article first published online: 22 NOV 2015 | DOI: 10.1111/echo.13124

  31. Case Reports

    1. The Strange Case of the Infarcted Myxoma

      Amedeo Pergolini, Giordano Zampi, Maria Denitza Tinti, Daniele Pontillo, Barbara Di Paolo, Vitaliano Buffa, Giovanni Pulignano, Paolo Giuseppe Pino, Giovanni Minardi and Francesco Musumeci

      Article first published online: 22 NOV 2015 | DOI: 10.1111/echo.13122


      We describe the case of a patient presenting with an acute coronary syndrome associated with an aneurysmatic apical left ventricular myxoma.

  32. Image Sections

    1. Right Coronary Artery Aneurysm with Fistula to the Coronary Sinus, Persistent Left Superior Vena Cava, Ruptured Anterior Leaflet Chordae Tendineae with Severe Mitral Regurgitation

      Claudia Cajas-Morales, Citlalic Martinez-Beltran, Sergio Criales-Vera, Jose Antonio Arias-Godinez and Nilda Espinola-Zavaleta

      Article first published online: 22 NOV 2015 | DOI: 10.1111/echo.13119


      We are reporting a case of a 52-year-old man with a 2-year history of dyspnea on moderate exertion and orthopnea. In the last year, paroxysmal nocturnal dyspnea developed. Echocardiography showed an aneurysm of the right coronary artery with a fistula to the coronary sinus, persistent left superior vena cava, and ruptured anterior mitral leaflet chordae tendineae with severe mitral regurgitation. The computed tomography confirmed these findings. The patient was scheduled for surgery.

  33. Images Sections

    1. A Patient with Metastatic Small-Cell Lung Cancer and Giant Right Ventricular Mass

      Rahman Shah, Elizabeth John, Tai-Hwang M. Fan, Genina Ruff, M. Rehan Khan and Lee C. Holt

      Article first published online: 17 NOV 2015 | DOI: 10.1111/echo.13105


      A 62-year-old male presented with right-sided weakens. His MRI of the brain showed multiple ring-enhancing lesions consistent with metastatic disease. His chest X-rays showed a large mass in the right upper lobe. Follow-up chest CT showed a large lobulated mass in the upper lobe of the right lung and a large filling defect in the right ventricle. Transthoracic echocardiography showed a large mass in the right ventricle. Biopsy of the right lung mass showed small-cell carcinoma. We concluded metastasis in the right ventricle and brain from the primary small-cell lung cancer.

  34. Original Investigations

    1. Accuracy of Imaging Modalities in Detection of Baffle Leaks in Patients Following Atrial Switch Operation

      Carolyn M. Wilhelm, Tracey L. Sisk, Sharon L. Roble, Joanne L. Chisolm, Ilija Janevski, John P. Cheatham and Clifford L. Cua

      Article first published online: 15 NOV 2015 | DOI: 10.1111/echo.13097

  35. Image Sections

    1. Cardiac Amorphous Tumor on the Mitral Valve

      Cetin Gecmen, Mehmet Inanir, Gonca G. Gecmen, Fatih Yilmaz and Nihal Ozdemir

      Article first published online: 6 NOV 2015 | DOI: 10.1111/echo.13109


      A 62-year-old male patient with a history of hypertension, dialysis-dependent chronic renal failure, and coronary artery bypass graft presented to our clinic with dyspnea. Transthoracic echocardiographic assessment revealed moderate aortic stenosis (mean gradient: 32 mmHg), mild left ventricular systolic dysfunction (global left ventricle ejection fraction: 45%), and a mobile, racket-shaped hyperechogenic mass of 2.1 × 1.1 cm in posterior mitral leaflet, which partially moved into the left ventricle during diastole. Transesophageal echocardiography revealed the mobile mass on the posterior leaflet as well as mild mitral regurgitation. During surgery, the mass was excised from the P2 scallop of posterior mitral leaflet. On histologic examination, hematoxylin and eosin–stained section of the 10 × 20 mm mass showed calcified nodules on an amorphous background of fibrin material and foreign body giant cells.

  36. Original Investigations

    1. Is Right Ventricular Remodeling in Pulmonary Hypertension Dependent on Etiology? An Echocardiographic Study

      Sorin Giusca, Elena Popa, Mihaela Silvia Amzulescu, Ioana Ghiorghiu, Ioan Mircea Coman, Bogdan A. Popescu, Marion Delcroix, Jens-Uwe Voigt, Carmen Ginghina and Ruxandra Jurcut

      Article first published online: 6 NOV 2015 | DOI: 10.1111/echo.13112

  37. Images Sections

    1. Parachute-Like Mitral Valve with Symptomatic Stenosis—Imaging with Transthoracic and Transesophageal Three-Dimensional Echocardiography and Treatment Implications

      Karina Wierzbowska-Drabik and Jarosław Damian Kasprzak

      Article first published online: 6 NOV 2015 | DOI: 10.1111/echo.13114


      Parachute and parachute-like mitral valve are rarely encountered in adults congenital abnormalities in which diagnosis usually relies on detailed echocardiographic examination with special focus on three-dimensional imaging. In children, these valves often coexist with other congenital anomalies such as aortic stenosis, atrial septal defect, hypoplastic left heart syndrome or form Shone complex together with supravalvular mitral ring, subaortic stenosis, and aortic coarctation. We described a woman with moderate stenosis and mild regurgitation of mitral valve diagnosed as congenital parachute-like anomaly during transthoracic and transesophageal examination. Precise recognition of morphology disqualified the patient from percutaneous balloon angioplasty.

  38. Original Investigations

    1. Utility of Real Time 3D Echocardiography for the Assessment of Left Ventricular Mass in Patients with Hypertrophic Cardiomyopathy: Comparison with Cardiac Magnetic Resonance

      Gustavo P. Avegliano, Juan P. Costabel, Federico M. Asch, Agustina Sciancalepore, Paola Kuschnir, Marina Huguet, Catalina Tobon-Gomez, Alejandro F. Frangi and Ricardo Ronderos

      Article first published online: 3 NOV 2015 | DOI: 10.1111/echo.13096

    2. Archeological Echocardiography: Digitization and Speckle Tracking Analysis of Archival Echocardiograms in the HyperGEN Study

      Frank G. Aguilar, Senthil Selvaraj, Eva E. Martinez, Daniel H. Katz, Lauren Beussink, Kwang-Youn A. Kim, Jie Ping, Laura Rasmussen-Torvik, Amita Goyal, Jin Sha, Marguerite R. Irvin, Donna K. Arnett and Sanjiv J. Shah

      Article first published online: 3 NOV 2015 | DOI: 10.1111/echo.13095

    3. A Novel 13-Segment Standardized Model for Assessment of Right Ventricular Function Using Two-Dimensional iRotate Echocardiography

      Jackie S. McGhie, Myrthe E. Menting, Wim B. Vletter, René Frowijn, Jolien W. Roos-Hesselink, Osama I. I. Soliman, Heleen B. van der Zwaan, Marcel L. Geleijnse and Annemien E. van den Bosch

      Article first published online: 2 NOV 2015 | DOI: 10.1111/echo.13102

    4. Strain Analysis by Tissue Doppler Imaging: Comparison of Conventional Manual Measurement with a Semiautomated Approach

      Johannes Schmid, Reinhard Kaufmann, Martin R. Grübler, Nicolas Verheyen, Frank Weidemann and Josepha S. Binder

      Article first published online: 30 OCT 2015 | DOI: 10.1111/echo.13100

    5. Evaluation of Pulmonary Artery Stiffness in Patients with Obstructive Sleep Apnea Syndrome

      Ibrahim Halil Altıparmak, Muslihittin Emre Erkus, Mustafa Polat, Zafer Hasan Ali Sak, Funda Yalcın, Ozgur Gunebakmaz, Yusuf Sezen, Zekeriya Kaya and Recep Demirbag

      Article first published online: 29 OCT 2015 | DOI: 10.1111/echo.13098

  39. Image Sections

    1. Giant Hydatid Cyst of the Interventricular Septum

      Neeraj Parakh, Priya Jagia, Milind Hote and Sudhir Arava

      Article first published online: 26 OCT 2015 | DOI: 10.1111/echo.13090


      This case illustrates one of the largest reported hydatid cyst of the interventricular septum that almost obliterated both ventricular cavities. Diagnosis of hydatid cyst was confirmed on echocardiography, cardiac MRI, CT chest, and postoperative histopathology.

  40. Original Investigations

    1. Temporal Trends of Cardiac Chambers Function with Trastuzumab in Human Epidermal Growth Factor Receptor II–Positive Breast Cancer Patients

      Sherif Moustafa, Katie Murphy, Bhargava K. Nelluri, Donald Northfelt, Parth Shah, Howard Lee, Susan Wilansky, Tasneem Z. Naqvi, Susan Meyer and Farouk Mookadam

      Article first published online: 24 OCT 2015 | DOI: 10.1111/echo.13087

    2. Correlation of Left Atrial Strain and Doppler Measurements with Invasive Measurement of Left Ventricular End-Diastolic Pressure in Patients Stratified for Different Values of Ejection Fraction

      Matteo Cameli, Stefania Sparla, Maurizio Losito, Francesca M. Righini, Daniele Menci, Matteo Lisi, Flavio D'Ascenzi, Marta Focardi, Roberto Favilli, Carlo Pierli, Massimo Fineschi and Sergio Mondillo

      Article first published online: 23 OCT 2015 | DOI: 10.1111/echo.13094

    3. Predictors of Future Atrial Fibrillation Development in Patients with Hypertrophic Cardiomyopathy: A Prospective Follow-Up Study

      Kamil Tuluce, Selcen Yakar Tuluce, Nihan Kahya Eren, Ugur Kocabas, Filiz Akyildiz Akcay, Ramazan Gunduz, Zehra I. Akyildiz and Oktay Ergene

      Article first published online: 23 OCT 2015 | DOI: 10.1111/echo.13093

    4. Strain Analysis in the Detection of Myocardial Infarction at the Acute and Chronic Stages

      Noa Bachner-Hinenzon, Assaf Malka, Yaron Barac, David Meerkin, Offir Ertracht, Shemy Carasso, Rona Shofti, Marina Leitman, Zvi Vered, Dan Adam and Ofer Binah

      Article first published online: 28 SEP 2015 | DOI: 10.1111/echo.13079

    5. Prognostic Value of Real Time Myocardial Contrast Echocardiography after Percutaneous Coronary Intervention

      Lixia Yang, Chunmei Xia, Yuming Mu, Lina Guan, Chunmei Wang, Qi Tang, Flavia Gomes Verocai, Lea Mirian Barbosa da Fonseca and Ming Chi Shih

      Article first published online: 28 SEP 2015 | DOI: 10.1111/echo.13061

    6. Cardiac Computed Tomography versus Echocardiography in the Assessment of Stenotic Rheumatic Mitral Valve

      Hale Unal Aksu, Sevket Gorgulu, Mustafa Diker, Omer Celik, Huseyin Aksu, Derya Ozturk, Adem Kırıs, Ali Kemal Kalkan, Mehmet Erturk and İhsan Bakır

      Article first published online: 18 SEP 2015 | DOI: 10.1111/echo.13076

    7. Quantitative Assessment of Ventricular Septal Contour for Estimation of Right Ventricular Pressure

      Timotheus Watson, Courtney E. McCracken, Timothy Slesnick, Usama Kanaan, William L. Border and Ritu Sachdeva

      Article first published online: 18 SEP 2015 | DOI: 10.1111/echo.13080

    8. Exercise-Induced Abnormal Increase of Systolic Pulmonary Artery Pressure in Adult Patients With Sickle Cell Anemia: An Exercise Stress Echocardiography Study

      Newton Nunes de Lima-Filho, Maria Stella Figueiredo, Perla Vicari, Rodolfo Cançado, Antonio Carlos de Camargo Carvalho, José Orlando Bordin and Orlando Campos

      Article first published online: 18 DEC 2014 | DOI: 10.1111/echo.12853


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