Cover image for Vol. 31 Issue 4

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Navin C. Nanda

Impact Factor: 1.261

ISI Journal Citation Reports © Ranking: 2012: 84/124 (Cardiac & Cardiovascular Systems)

Online ISSN: 1540-8175


  1. 1 - 100
  2. 101 - 130
  1. Original Investigations

    1. The Additional Value of Three-Dimensional Transesophageal Echocardiography in Complex Aortic Prosthetic Heart Valve Endocarditis

      Wilco Tanis, Arco J. Teske, Lex A. van Herwerden, Steven Chamuleau, Folkert Meijboom, Ricardo P.J. Budde and Maarten-Jan Cramer

      Article first published online: 12 APR 2014 | DOI: 10.1111/echo.12602

  2. Case Reports

    1. Intraoperative Evaluation of Right Ventricular Outflow Tract Myxoma by Real Time Three-Dimensional Transesophageal Echocardiography

      Chan Chen, Jun Gu, Wei Meng, Haibo Song, Da Zhu, Shu Zhang and Eryong Zhang

      Article first published online: 12 APR 2014 | DOI: 10.1111/echo.12578


      Cardiac myxoma arising from right ventricular outflow tract (RVOT) is extremely rare, but could cause major clinical sequelae and pose considerable diagnostic and therapeutic challenges. Here, we report the intraoperative application of real time three-dimensional transesophageal echocardiography (RT3DTEE) in the assessment of a patient with a RVOT myxoma. RT3DTEE clearly assess the characteristics of the mass, such as the size, shape, attachment points, and composition. With the intraoperative guidance of RT3DTEE, the patient underwent successful removal of the mass.

    2. Isolated Supravalvular Pulmonary Stenosis: A Rare Echocardiographic Finding

      Stefano Maffè, Pierfranco Dellavesa, Paola Paffoni, Franco Zenone, Lorenzo Cucchi, Anna Maria Paino, Luca Bergamasco, Lara Baduena, Nicolò Franchetti Pardo, Marco Zanetta and Umberto Parravicini

      Article first published online: 5 APR 2014 | DOI: 10.1111/echo.12612


      Here, we report a case of a 76-year-old patient with isolated, severely obstructive, pulmonary supravalvular stenosis. The peculiarity of the present case is the paucity of symptoms and lack of changes in right heart sections, despite of the importance of stenosis. The report confirms the utility of transthoracic two- and three-dimensional echocardiography and transesophageal echocardiography in the detection and quantification of this rare anomaly.

  3. Original Investigations

    1. Blood Flow Imaging in Transesophageal Echocardiography during Atrial Septal Defect Closure: A Comparison with the Current References

      Siri Ann Nyrnes, Lasse Løvstakken, Gaute Døhlen, Eirik Skogvoll, Hans Torp, Terje Skjærpe, Gunnar Norgård, Stein Samstad, Torbjørn Graven and Bjørn Olav Haugen

      Article first published online: 5 APR 2014 | DOI: 10.1111/echo.12610

  4. Image Sections

    1. An Unusual Cause of Bioprosthetic Mitral Valve Obstruction: Calcified Septum of Cor Triatriatum Sinister

      Macit Kalcik, M. Ozan Gursoy, Cüneyt Toprak, Mahmut Yesin, Suleyman Karakoyun, M. Altuğ Tuncer and Mehmet Ozkan

      Article first published online: 5 APR 2014 | DOI: 10.1111/echo.12607


      Cor triatriatum sinister is a rare congenital cardiac anomaly in which the left atrium is divided into 2 chambers by a fibromuscular septum. Although the disease is generally diagnosed in early childhood, some patients remain asymptomatic until adulthood. Here, we present an unusual presentation of cor triatriatum sinister as a unique cause of mitral bioprosthetic valve obstruction. The calcified septum of the cor triatriatum sinister was delineated with the utility of two-dimensional and real time three-dimensional transesophageal echocardiography.

  5. Original Investigations

    1. Identification of Prolapsing Mitral Valve Scallops by a Three-Dimensional Multiplanar Reconstruction Method

      Nausheen Akhter, Qiong Zhao, Adin-Cristian Andrei, Bonnie Kane, Patrick McCarthy and Vera H. Rigolin

      Article first published online: 5 APR 2014 | DOI: 10.1111/echo.12608

    2. Ia Diastolic Dysfunction: An Echocardiographic Grade

      Anil Pandit, Farouk Mookadam, Fayaz A. Hakim, Eoin Mulroy, Rayya Saadiq, Mairead Doherty, Stephen Cha, James Seward and Susan Wilansky

      Article first published online: 4 APR 2014 | DOI: 10.1111/echo.12600

  6. Images – Pediatric

    1. Intracardiac Echocardiography of Ebstein's Anomaly

      Claire Dauphin, Aurélie Chalard and Jean-René Lusson

      Article first published online: 4 APR 2014 | DOI: 10.1111/echo.12599


      We report the case of a 9-year-old girl with a severe form of Ebstein's anomaly. Intracardiac echocardiography used for guidance in closure of the atrial septal defect (ASD) showed a clear picture of nondelamination of the septal and posterior leaflets of the tricuspid valve.

  7. Image Sections

    1. Three-Dimensional Transesophageal Echocardiography for Guiding Percutaneous Fontan Fenestration Closure

      George Giannakoulas and Vasilios Thanopoulos

      Article first published online: 4 APR 2014 | DOI: 10.1111/echo.12606

      Mini Abstract

      The presented case highlights the important complementary role of real time 3D transesophageal echocardiography in the guidance of transcatheter closure of a surgically created fenestration after Fontan operation.

  8. Original Investigations

    1. Clinical Settings Leading to Presystolic Tricuspid Regurgitation

      Piotr Szymański, Magdalena Lipczyńska, Anna Klisiewicz and Piotr Hoffman

      Article first published online: 4 APR 2014 | DOI: 10.1111/echo.12604

    2. Atrial Mechanics after Surgical Repair of Tetralogy of Fallot

      Jia Hou, Hong-kui Yu, Sophia J Wong and Yiu-fai Cheung

      Article first published online: 4 APR 2014 | DOI: 10.1111/echo.12611

  9. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Role of Echocardiography in the Treatment of Cardiac Tamponade

      P. A. N. Chandraratna, Dilbahar S. Mohar and Peter F. Sidarous

      Article first published online: 4 APR 2014 | DOI: 10.1111/echo.12605

  10. Research from or in Collaboration with the University of Alabama at Birmingham

  11. Original Investigations

    1. Accuracy of Conventional Transthoracic Echocardiography for the Diagnosis of Intracardiac Right-to-Left Shunt: A Meta-Analysis of Prospective Studies

      Mohammad Khalid Mojadidi, Jared S. Winoker, Scott C. Roberts, Pavlos Msaouel, Muhammad Omer Zaman, Rubine Gevorgyan and Jonathan M. Tobis

      Article first published online: 2 APR 2014 | DOI: 10.1111/echo.12583

    2. Effects of Batroxobin with Continuous Transcranial Doppler Monitoring in Patients with Acute Cerebral Stroke: A Randomized Controlled Trial

      He Yitao, Ma Kefu, Tang Bingshan, Fu Xuejun, Zhan Ying, Cai Zhili, Jiang Xin and Yi Guo

      Article first published online: 31 MAR 2014 | DOI: 10.1111/echo.12559

    3. Relation of Myocardial Systolic Mechanics to Serum Ferritin Level as a Prognosticator in Thalassemia Patients Undergoing Repeated Transfusion

      Ming-Ren Chen, Ho-Shun Ko, Tze-Fan Chao, Hsi-Che Liu, Jen-Yuan Kuo, Bernard E. Bulwer, Hung-I Yeh and Chung-Lieh Hung

      Article first published online: 27 MAR 2014 | DOI: 10.1111/echo.12590

    4. Does Gestational Diabetes History Increase Epicardial Fat and Carotid Intima Media Thickness?

      Mustafa Caliskan, Ozge Telci Caklili, Zuhal Caliskan, Cevdet Duran, Faika C. Çiftçi, Enver Avci, Hakan Güllü, Mustafa Kulaksizoglu, Harun Koca and Haldun Muderrisoglu

      Article first published online: 26 MAR 2014 | DOI: 10.1111/echo.12597

  12. Case Reports – Pediatric

    1. Cardiac Function and Its Evolution with Pulmonary Vasodilator Therapy: A Myocardial Deformation Study

      Arvind Sehgal, Masitah Ibrahim and Kenneth Tan

      Article first published online: 26 MAR 2014 | DOI: 10.1111/echo.12596


      Speckle tracking echocardiography–derived myocardial strain has useful clinical applications in adults with pulmonary hypertension (PH) as well as preterm infants with chronic lung disease. It is considered more sensitive compared to conventional indices. This report presents a 3-month-old infant with PH and poor right ventricular function who was treated with pulmonary vasodilator therapy. Impaired myocardial strain improved after inhaled nitric therapy. Strain analysis can help improve understanding of cardiac adaptation in critical clinical situations.

  13. Original Investigations

  14. Image Sections

    1. Unroofed Coronary Sinus Atrial Septal Defect: Diagnosis by Multimodality Cardiac Imaging

      Ahmed Aljizeeri, Carole J. Dennie, Kwan-Leung Chan and Luc M. Beauchesne

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12588


      Unroofed coronary sinus is a rare congenital cardiac anomaly. It is a communication between the coronary sinus and the left atrium. The associated interatrial shunt can cause right atrial volume overload and possible paradoxical embolization. It is classified into four subtypes on the basis of the extent of the roof absence and the presence of persistent left superior vena cava. Although the diagnosis can be suspected by two-dimensional echocardiography, three-dimensional echocardiography and computerized cardiac tomography provide incremental value in delineating the precise anatomy of this condition.

    2. A Vanishing Left Ventricular Outflow Tract Mass: An Uncommon Manifestation of Systemic Lupus Erythematosus

      Rajiv Ananthakrishna, Nagaraja Moorthy, Prabhavathi Bhat and Manjunath C Nanjappa

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12598


      A 27-year-old female with a history of second trimester abortion was referred for evaluation of transient ischemic attack. Echocardiography revealed a large, irregular, mobile mass attached to the right coronary cusp of aortic valve. Investigations were consistent with antiphospholipid antibody syndrome, secondary to systemic lupus erythematosus. She was started on oral anticoagulation. Serial echocardiography showed regression of the mass, with complete resolution at 2 months. We highlight an uncommon manifestation of systemic lupus erythematosus, in the setting of a prothrombotic milieu. Prompt recognition is essential for appropriate therapy and averts the need for surgery.

  15. Original Investigations

  16. Case Reports

    1. Two Different Presentations of Sinus of Valsalva Aneurysm

      Nishit Patel, Talla A. Rousan, Marvin D. Peyton and Chittur A. Sivaram

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12593


      Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly that can be congenital or acquired. We report 2 cases of SVA: a large right SVA obstructing the right ventricular outflow tract (RVOT) in a patient presenting with syncope, and a ruptured right SVA into the right atrium in a patient presenting with acute onset chest pain.

  17. Original Investigations

    1. Left Ventricular Vortices as Observed by Vector Flow Mapping: Main Determinants and their Relation to Left Ventricular Filling

      Daniel Rodríguez Muñoz, José Luis Moya Mur, Covadonga Fernández-Golfín, Derly Carlos Becker Filho, Ariana González Gómez, Sara Fernández Santos, Carla Lázaro Rivera, Luis Miguel Rincón Díaz, Eduardo Casas Rojo and José Luis Zamorano Gómez

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12584

    2. Echocardiography-Based Hemodynamic Management of Left Ventricular Diastolic Dysfunction: A Feasibility and Safety Study

      Sasha K. Shillcutt, Candice R. Montzingo, Ankit Agrawal, Maseeha S. Khaleel, Stacey L. Therrien, Walker R. Thomas, Thomas R. Porter and Tara R. Brakke

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12574

    3. Strain Analysis during Exercise in Patients with Asymptomatic Atrial Septal Defect

      Onur Baydar, Veysel Oktay, Umit Yasar Sinan, Sinem Cakal, Beytullah Cakal, Ugur Coskun and Ahmet Yildiz

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12570

  18. Image Sections

    1. Systolic Mitral Valve Opening and Absent Isovolumic Relaxation: Unusual Hemodynamics of Severe Mitral Regurgitation

      Olayinka O. Afolabi-Brown, D. Lynn Morris and Gregg S. Pressman

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12576


      An 84-year-old man with dyspnea was found to have severe mitral regurgitation on echocardiography. Interestingly, the mitral valve opened prior to aortic valve closure with both valves briefly open together; hence the isovolumic relaxation phase is absent.

  19. Original Investigations

  20. Case Reports

    1. Role of Three-Dimensional Echocardiography in Structural Complications after Acute Myocardial Infarction

      Davide Ermacora, Denisa Muraru, Sara Pontarollo, Simona Casablanca, Ugolino Livi, Sabino Iliceto and Luigi P. Badano

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12585


      We report 3 emblematic cases which show how three-dimensional echocardiography (3DE) can provide unique information useful to address management of structural complications in patients with acute myocardial infarction: (1) detailed assessment of size, location, and morphology of an apical ventricular septal defect (VSD) obtained with transthoracic 3DE was pivotal in referring a patient to percutaneous closure; (2) size and location of a complex inferior VSD with irregular margins advised against percutaneous closure; and (3) Transesophageal 3DE assisted surgeons to choose between reparative or replacement surgery for an acute mitral regurgitation due to complete papillary muscle rupture.

  21. Original Investigations

    1. Right Ventricular Isovolumic Acceleration in Acute Pulmonary Embolism

      Mehmet Ali Cetiner, Muhammet Rasit Sayin, Nesligul Yildirim, Turgut Karabag, Sait Mesut Dogan, Emrah Kucuk and Mustafa Aydin

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12579

  22. Image Sections

    1. Posterior Mitral Leaflet Left Atrial Anomalous Chord in the Absence of Surgical Mitral Regurgitation

      Julie W. Martin and David S. Bach

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12582


      Aberrant left atrial mitral valve chords are rare causes of mitral regurgitation (MR). An aberrant chord to the posterior mitral valve leaflet has not been reported. Transesophageal echocardiogram demonstrated a chord-like structure from the left atrium to the middle (P2) scallop of the posterior mitral leaflet, causing focal P2 prolapse without typical myxomatous degeneration. Three-dimensional images revealed that the chord terminated on a papillary muscle-like structure within the left atrium. There was mild MR. Focal mitral leaflet prolapse without typical myxomatous change may herald the presence of an aberrant chord.

  23. Original Investigations

    1. Evaluation of Human Immunodeficiency Virus Infection-Related Left Ventricular Systolic Dysfunction by Tissue Doppler Strain Echocardiography

      Imran Onur, Baris Ikitimur, Fahrettin Oz, Ahmet Ekmekci, Ali Elitok, Arif Atahan Cagatay, Kamil Adalet, Ahmet Kaya Bilge and Mehmet Gungor Kaya

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12569

  24. Image Sections

    1. A Case of Right Atrial Appendage Aneurysm in a 62-Year-Old Man

      You-Feng Xu, Fei Yu, Feng Mao, Xian-wang Ye, Xin-Zhong Ruan and Shengmin Zhang

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12575


      Right atrial appendage aneurysm (RAAA) is a rare malformation of the heart. Here, we present a case of RAAA in an elderly man, who has remained asymptomatic for over 10 months of follow-up. The aneurysm was initially discovered by echocardiography, and confirmed by further investigations using cardiac magnetic resonance (CMR) imaging and 320-row detector computed tomography (320R-CT).

  25. Original Investigations

    1. Effect of Increased Severity of Mitral Regurgitation and Preprocedural Right Ventricular Systolic Dysfunction on Biventricular and Left Atrial Mechanical Functions Following Percutaneous Mitral Balloon Valvuloplasty

      Kursat Tigen, Selcuk Pala, Beste Ozben Sadic, Tansu Karaahmet, Cihan Dundar, Mustafa Bulut, Akin Izgi, Ali Metin Esen and Cevat Kirma

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12580

  26. Image Sections

    1. Double-Outlet Right Atrium Associated with Hypoplastic Right Heart Structures and Aortic Stenosis: Echocardiographic Features

      Poonam Punjwani Thankavel, Barry Gabbert and Claudio Ramaciotti

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12565


      Double-outlet right atrium, also known as straddling tricuspid valve without a ventricular septal defect, is an extremely rare congenital cardiac anomaly, in which the tricuspid valve has 2 ostia. We describe an infant with this finding in association with hypoplastic right heart structures and a dysplastic aortic valve.

  27. Case Reports

    1. Isolated Tricuspid Valve Repair for Libman-Sacks Endocarditis

      Ali Kemal Gur, Dolunay Odabasi, Ayse Gul Kunt and Alper Sami Kunt

      Article first published online: 25 MAR 2014 | DOI: 10.1111/echo.12558


      Cardiac involvement is a well-known complication of systemic lupus erythematosus (SLE), which can involve most cardiac components, including pericardium, conduction system, myocardium, heart valves, and coronary arteries. Libman-Sacks (verrucous) endocarditis is the characteristic cardiac valvular manifestation. Although isolated tricuspid valve involvement is quite rare, we report a patient with SLE who had tricuspid stenosis caused by Libman-Sacks endocarditis. The patient underwent successful commisurotomy and Kay annuloplasty on the tricuspid valve under cardiopulmonary bypass.

  28. Original Investigations

    1. Left Ventricular Twisting Modifications in Patients with Left Ventricular Concentric Hypertrophy at Increasing After-Load Conditions

      Amato Santoro, Federico Alvino, Giovanni Antonelli, Valerio Zacà, Susanna Benincasa, Stefano Lunghetti and Sergio Mondillo

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12555

  29. Image Section

    1. Rapid Visualization of PTSMA Target Area by Real Time 3D Myocardial Contrast Echocardiography

      Nikola Bogunovic, Frank van Buuren, Dieter Horstkotte and Lothar Faber

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12567


      Percutaneous transluminal septal myocardial ablation (PTSMA) is an accepted strategy to reduce dynamic left ventricular outflow tract (LVOT) obstruction in HOCM. Periinterventional intramyocardial 2D contrast echocardiography (2D-CE) is the primary imaging technique to identify the interventional target region. The role of intramyocardial 3D-CE in a PTSMA procedure has not been described yet. Real time 3D technique will be able to present an “instantaneous overlook” of the target myocardium in 4 dimensions (3D + time), which may increase speed and safety of the procedure. We present a case with HOCM undergoing PTSMA under additional 3D-CE control of the target area.

  30. Original Investigations

    1. Three-Dimensional Speckle Tracking Echocardiography Allows Detailed Evaluation of Left Atrial Function in Hypertrophic Cardiomyopathy–Insights from the MAGYAR-Path Study

      Péter Domsik, Anita Kalapos, Számi Chadaide, Róbert Sepp, Péter Hausinger, Tamás Forster and Attila Nemes

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12568

  31. Challenging Cases

  32. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Cor Triatriatum Sinister: A Patient, a Review, and Some Unique Findings

      Patrick T. Strickland, Maria A. Pernetz, Maan Jokhadar, Greg Hartlage and Stephen Clements

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12547

  33. Image Sections

    1. Spontaneous Bileaflet Chordal Rupture Secondary to Myxomatous Degeneration of the Mitral Valve

      Lutfi Ocal, Macit Kalcik, Cuneyt Toprak, Alev Kılıcgedik, Atilla Koyuncu, Gökhan Kahveci and Mehmet Ozkan

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12573


      Various pathological changes in the mitral valve apparatus have been reported to be associated with ruptured chordae tendineae. Myxomatous degeneration is one of the most common etiologies. The incidence of posterior chordal rupture is higher than that of anterior mitral leaflet. However, spontaneous rupture of both anterior and posterior chordae is very rare. Herein, we present a patient with severe mitral regurgitation due to bileaflet chordal rupture, evaluated by two-dimensional and real time three-dimensional transesophageal echocardiography.

  34. Image Section

    1. Posteromedial Papillary Muscle Rupture Following Percutaneous Mitral Balloon Valvotomy

      Göksel Açar, Cuneyt Toprak, Anıl Avci, Suleyman Cagan Efe and Ali Metin Esen

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12564


      We report a case of Inoue balloon mitral valvotomy in a patient with low echo score that was complicated by severe regurgitation caused by a rupture of a papillary muscle, which only became apparent the day after the procedure. Our case highlights the importance of the follow-up of patients undergoing balloon mitral valvotomy even following a successful procedure on suitable valves.

  35. Review Articles

    1. Evaluation of Right Ventricular Function in Adults with Congenital Heart Defects

      Claudio Bussadori, Giovanni Di Salvo, Francesca R. Pluchinotta, Luciane Piazza, Giampiero Gaio, Maria Giovanna Russo and Mario Carminati

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12566

  36. Original Investigations

    1. Impact of Azelnidipine and Amlodipine on Left Ventricular Mass and Longitudinal Function in Hypertensive Patients with Left Ventricular Hypertrophy

      Hirohiko Motoki, Jun Koyama, Atsushi Izawa, Takeshi Tomita, Yusuke Miyashita, Masafumi Takahashi and Uichi Ikeda

      Article first published online: 20 MAR 2014 | DOI: 10.1111/echo.12548

  37. Image Sections

    1. Iatrogenic External Pudendal Artery Pseudoaneurysm with a Communicating Arteriovenous Fistula–A Diagnostic and Therapeutic Pitfall

      Mai Tone Lønnebakken, Terje H. Larsen, Eva Gerdts and Ole Martin Pedersen

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12560


      Ultrasound is the preferred imaging modality in evaluation of iatrogenic pseudoaneurysms (PAs). This case illustrates that when a PA originating from the external pudendal artery, a side branch of the common femoral artery, is combined with a communicating arteriovenous fistula the diagnosis, having important therapeutic implications, may be misinterpreted by ultrasound.

  38. Case Reports

    1. Accessory Tricuspid Valve Leaflet and an Anomalous Muscle Bundle in the Right Ventricular Outflow Tract in a Patient with Double-Outlet Right Ventricle: A Rare Case Report

      Maryam Nabati, Mozhdeh Dabirian, Babak Bagheri, Ali Ghaemian and Mojtaba Shokri

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12553


      We report a very rare case of the concomitant occurrence of double-outlet right ventricle, an anomalous muscle bundle in the right ventricular outflow tract, and an accessory tricuspid valve leaflet in a 17-year-old male patient. The patient eventually died from severe decompensated heart failure.

  39. Original Investigations

  40. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Prosthetic Valve Strands

      Edmund Kenneth Kerut and Frederick Kushner

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12544

  41. Images - Pediatric

    1. Right Superior Vena Cava to Left Atrium: Importance of “Bubbling It Right

      Sudhir Suryakant Shetkar, Saurabh Kumar Gupta, Gurpreet Singh Gulati and Rajnish Juneja

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12562


      Bubble contrast echocardiogram is conventionally done through left hand while evaluating patients with unexplained cyanosis. We hereby report a case of anomalous drainage of superior vena cava to left atrium in child and highlight the importance of doing bubble contrast echocardiogram through right hand.

  42. Original Investigations

    1. Left Ventricular Twist and Ventricular–Arterial Coupling in Hypertensive Patients

      Hong-Won Shin, Hyungseop Kim, Jeong-Eun Lee, In-Cheol Kim, Hyuck-Jun Yoon, Hyoung-Seob Park, Yun-Kyeong Cho, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim and Kwon-Bae Kim

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12561

    2. Associations of Tissue Doppler Imaging with NT-proBNP and hs-TnT: A Pilot Study in End-Stage Renal Disease

      Ruth F. Dubin, Alexis L. Beatty, John R. Teerlink, Nelson B. Schiller, Dean Alokozai and Kirsten L. Johansen

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12552

  43. Case Reports

    1. Device Landing Zone Calcification Predicts Significant Paravalvular Regurgitation after Transcatheter Aortic Valve Replacement: A Real Time Three-Dimensional Transesophageal Echocardiography Study

      Hirotsugu Mihara, Kentaro Shibayama, Kenji Harada, Javier Berdejo, Yuji Itabashi, Raj R. Makkar and Takahiro Shiota

      Article first published online: 19 MAR 2014 | DOI: 10.1111/echo.12550


      Paravalvular regurgitation (PVR) after transcatheter aortic valve replacement (TAVR) is one of the major complications with negative clinical prognosis. Therefore, its prediction is important for further improvement of the outcome. We present a case with TAVR, in which we successfully evaluated aortic valve calcification protruding inward and into left ventricular outflow tract by real time three-dimensional transesophageal echocardiography, and predicted significant PVR after the procedure. In conclusion, device landing zone calcification protruding inward is a key for the prediction of significant PVR after TAVR.

    2. Multiple Giant Aneurysms and Stenoses of the Coronary and Systemic Arteries in an Infant with Kawasaki Disease at the Early Stage of Convalescent Period

      Filiz Ekici, Birgül Varan, Abdullah Kocabaş, İlkay Erdoğan, Sancar Eminoğlu and Doğukan Aktaş

      Article first published online: 14 FEB 2014 | DOI: 10.1111/echo.12535


      We report the case of a 4-month-old Turkish infant who was diagnosed with Kawasaki disease associated with multiple “super giant” coronary aneurysms, huge coronary thromboses, and massive pericardial effusion. Multiple systemic arterial aneurysms and stenoses were also detected in subclavian, axillary, renal, and iliac arteries as well as coronary arteries at the beginning of convalescent period.

  44. Original Investigations

    1. The Relationship between Neutrophil/Lymphocyte Ratio and Calcific Aortic Stenosis

      Anil Avci, Alizade Elnur, Acar Göksel, Fidan Serdar, Izci Servet, Koyuncu Atilla, Tabakcı Mehmet Mustafa, Toprak Cuneyt, Guler Yeliz, Bulut Mustafa and Esen Ali Metin

      Article first published online: 14 FEB 2014 | DOI: 10.1111/echo.12534

    2. High-Intensity Focused Ultrasound Ablation of Myocardium In Vivo and Instantaneous Biological Response

      Minjuan Zheng, Weihui Shentu, Dingzhang Chen, David J. Sahn and Xiaodong Zhou

      Article first published online: 10 FEB 2014 | DOI: 10.1111/echo.12526

    3. Characterization of Echocardiographic Measures of Cardiac Structure and Function in Healthy Octogenarians

      Akif Serhat Balcioğlu, Murtaza Emre Durakoğlugil, Kaan Okyay, Yusuf Tavil and Adnan Abaci

      Article first published online: 8 FEB 2014 | DOI: 10.1111/echo.12540

    4. Factors Predicting Long-Term Mortality in Patients with Hypertrophic Cardiomyopathy

      Cem Bostan, Umit Yasar Sinan, Polat Canbolat, Okay Abaci, Sezer Karcier Munipoglu and Serdar Kucukoglu

      Article first published online: 8 FEB 2014 | DOI: 10.1111/echo.12537

  45. Case Reports

    1. Cardiac Sarcoid: A Chameleon Masquerading as Hypertrophic Cardiomyopathy and Dilated Cardiomyopathy in the Same Patient

      Anushree Agarwal, Nasir Z. Sulemanjee, Omar Cheema, Francis X. Downey and A. Jamil Tajik

      Article first published online: 8 FEB 2014 | DOI: 10.1111/echo.12536


      A 28-year-old female patient was originally diagnosed as having nonobstructive hypertrophic cardiomyopathy (asymmetric septal thickness of 21 mm). She eventually progressed to class IV disability and was transferred to our medical center for advanced heart failure options. Echocardiogram revealed features of severe dilated cardiomyopathy with a thinned, scarred, akinetic, and bulging midseptum with sparing of the basal and apical septum, raising the suspicion of sarcoid, which was confirmed on ventricular biopsy. Thus, a distinctive appearance of the cardiac sarcoid spectrum from “hypertrophic” stage to thinned, scarred stage—masquerading as hypertrophic and then dilated cardiomyopathy—is demonstrated in our patient.

  46. Original Investigations

    1. Children with Chronic Renal Disease Undergoing Dialysis or Conservative Treatment–Differences in Structural and Functional Echocardiographic Parameters

      Valeska Tavares Scavarda, Aurélio Carvalho Pinheiro, Symône Damasceno Costa, Zélia Maria de Andrade, João Tomás de Abreu Carvalhaes, Orlando Campos, Antonio Carlos Carvalho and Valdir Ambrosio Moises

      Article first published online: 7 FEB 2014 | DOI: 10.1111/echo.12525

  47. Review Articles

  48. Original Investigations

    1. Assessment of Atrial Electromechanical Delay and P-Wave Dispersion in Patients with Psoriasis

      Abdulkadir Yildiz, Derya Ucmak, Mustafa Oylumlu, Meltem Z. Akkurt, Murat Yuksel, Mehmet Ata Akil, Halit Acet, Nihat Polat, Mesut Aydin and M. Zihni Bilik

      Article first published online: 7 FEB 2014 | DOI: 10.1111/echo.12530

  49. ECHO Rounds Section Editor: Edmund Kenneth Kerut, M.D.

    1. Echo Diagnosis of Rheumatic Tricuspid Valve Disease

      Katherine Denise Kerut and Edmund Kenneth Kerut

      Article first published online: 5 FEB 2014 | DOI: 10.1111/echo.12532

  50. Case Reports

    1. Pulmonary Arteriovenous Malformations Presenting as Platypnea-Orthodeoxia in Graft-Versus-Host Disease

      Mark Anderson, Siddharth Wayangankar, George Selby and Chittur A. Sivaram

      Article first published online: 5 FEB 2014 | DOI: 10.1111/echo.12542


      This case highlights the utility of agitated saline studies during transesophageal echocardiography for detection of pulmonary arteriovenous malformations (PAVM) as a viable alternative to contrast-enhanced imaging studies. In addition, this report represents the first documentation of PAVM arising as a complication of graft-versus-host disease after allogeneic hematopoietic stem cell transplant.

  51. Original Investigations

  52. Case Reports

    1. A Flail Anterior Tricuspid Leaflet Secondary to Anteroposterior Papillary Muscle Rupture in a Neonate

      Madhusudan Ambadas Yemul

      Article first published online: 4 FEB 2014 | DOI: 10.1111/echo.12522


      This article is a summary of a case of a neonate who presented with tricuspid valve insufficiency associated with papillary muscle rupture but, however, showed no signs of cardiac failure. The transthoracic three-dimensional echocardiographic findings in this case are described in detail herein.

  53. Review Articles

  54. Original Investigations

    1. Assessment of Aortic Arch Stiffness Using Pulse-Wave Tissue Doppler Imaging: A Transesophageal Echocardiographic Comparison Study of Acute Ischemic Stroke Patients and Stroke-Free Patients

      Kazuyoshi Kaneko, Tetsuya Takahashi, Hiroki Saito, Nobuyuki Kiribayashi, Koki Omi, Toshiki Sasaki, Takeshi Niizeki and Shigeo Sugawara

      Article first published online: 24 JAN 2014 | DOI: 10.1111/echo.12521

    2. Evaluation of Stroke Volume and Ventricular Mass in a Fetal Heart Model: A Novel Four-Dimensional Echocardiographic Analysis

      Meihua Zhu, Cole Streiff, Jill Panosian, David Roundhill, Michael Lapin, Boris Tutschek, Muhammad Ashraf and David J. Sahn

      Article first published online: 24 JAN 2014 | DOI: 10.1111/echo.12520

    3. Spirito–Maron Echocardiographic Score: A Marker for Morphological and Physiological Assessment of Patients with Hypertrophic Cardiomyopathy

      Inês Rangel, Alexandra Gonçalves, Carla de Sousa, Ana Sofia Correia, Teresa Pinho, António José Madureira, Elisabete Martins, José Silva Cardoso, Filipe Macedo and Maria Júlia Maciel

      Article first published online: 24 JAN 2014 | DOI: 10.1111/echo.12471

    4. New Universal Strain Software Accurately Assesses Cardiac Systolic and Diastolic Function Using Speckle Tracking Echocardiography

      Theodore J. Kolias, Peter G. Hagan, Stanley J. Chetcuti, Diane L. Eberhart, Nicole M. Kline, Sean D. Lucas and James D. Hamilton

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12512

    5. Neutrophil-to-Lymphocyte Ratio May Predict Subclinical Atherosclerosis in Patients with Psoriasis

      Mustafa Yurtdaş, Yalin T. Yaylali, Yüksel Kaya, Mahmut Özdemir, İlker Özkan and Nesim Aladağ

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12511

    6. Relation between QRS Duration and Atrial Synchronicity in Patients with Systolic Heart Failure

      Osman Turak, Fırat Özcan, Uğur Canpolat, Fatma Nurcan Başar, Ahmet Işleyen, Erdoğan Sökmen, Omaç Tüfekçioğlu, Kumral Çağli and Sinan Aydoğdu

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12504

    7. Chronic Kidney Disease is Independently Associated with Alterations in Left Atrial Function

      Krishna K. Kadappu, Ario S. Kuncoro, Leia Hee, Anathakrishnapuram Aravindan, Stephen T. Spicer, Govindarajan Suryanarayanan, Wei Xuan, Anita Boyd, John K. French and Liza Thomas

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12503

    8. Impact of Three-Dimensional Imaging and Pressure Recovery on Echocardiographic Evaluation of Severe Aortic Stenosis: A Pilot Study

      Barbara E. Stähli, Amr Abouelnour, Thi Dan Linh Nguyen, Alessandra Vecchiati, Willibald Maier, Thomas F. Lüscher, Thomas Frauenfelder and Felix C. Tanner

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12509

    9. Hemodynamic Benefit of Rest and Exercise Optimization of Cardiac Resynchronization Therapy

      Tony Stanton, Brian A. Haluska, Rodel Leano, Thomas H. Marwick and On behalf of the CORE Investigators

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12506

    10. Educational Intervention to Reduce Inappropriate Transthoracic Echocardiograms: The Need for Sustained Intervention

      Rajan Sacha Bhatia, David M. Dudzinski, Creagh E. Milford, Michael H. Picard and Rory B. Weiner

      Article first published online: 22 JAN 2014 | DOI: 10.1111/echo.12505

    11. Double Jeopardy in the Echocardiography Laboratory: Coexistence of Two Distinct Cardiomyopathies?

      Timothy E. Paterick, Alix J. Tercius, Anushree Agarwal, Shannon C. Treiber, Bijoy K. Khandheria and A. Jamil Tajik

      Article first published online: 21 JAN 2014 | DOI: 10.1111/echo.12502

    12. High Plasma Human Atrial Natriuretic Peptide and Reduced Transthoracic Left Atrial Appendage Wall-Motion Velocity Are Noninvasive Surrogate Markers for Assessing Thrombogenesis in Patients with Paroxysmal Atrial Fibrillation

      Naoyasu Yoshida, Mitsunori Okamoto, Hidekazu Hirao, Kazuyoshi Suenari, Kiyomi Nanba, Mio Uchida, Ryo Yamazato, Yuichiro Watari, Yukihiro Fukuda and Hironori Ueda

      Article first published online: 28 DEC 2013 | DOI: 10.1111/echo.12501

    13. Evaluation of Atrial Electromechanical Delay and Its Relationship to Inflammation and Oxidative Stress in Patients with Chronic Obstructive Pulmonary Disease

      Gurkan Acar, Hasan Kahraman, Murat Akkoyun, Metin Kilinc, Cemil Zencir, Edagani Yusufoglu, Imran Dirnak, Hatice Sahin, Soner Olmez, Ahmet Akcay and Idris Ardic

      Article first published online: 24 DEC 2013 | DOI: 10.1111/echo.12442

    14. Epicardial Adipose Tissue Thickness in Hemodialysis Patients

      Burak Altun, Hakan Tasolar, Necmi Eren, Emine Binnetoğlu, Mehzat Altun, Ahmet Temiz, Emine Gazi, Ahmet Barutcu, Orcun Altunoren, Yucel Colkesen and Fatma Uysal

      Article first published online: 24 DEC 2013 | DOI: 10.1111/echo.12498

    15. Does Accessory Pathway Significantly Alter Left Ventricular Twist/Torsion? A Study in Wolff-Parkinson-White Syndrome by Velocity Vector Imaging

      Farimah Aminian, Maryam Esmaeilzadeh, Hassan Moladoust, Majid Maleki, Soraya Shahrzad, Zahra Emkanjoo and Anita Sadeghpour

      Article first published online: 24 DEC 2013 | DOI: 10.1111/echo.12470

    16. Left Atrial Remodeling and Recurrence of Congestive Heart Failure in Patients Initially Diagnosed with Heart Failure

      Kazuto Yamaguchi, Hiroyuki Yoshitomi, Shimpei Ito, Saki Ito, Tomoko Adachi, Hirotomo Sato, Nobuhide Watanabe, Nobuhiro Kodani, Takashi Sugamori, Akihiro Endo, Nobuyuki Takahashi and Kazuaki Tanabe

      Article first published online: 24 DEC 2013 | DOI: 10.1111/echo.12497

    17. Nonsymmetric Myocardial Contribution to Supranormal Right Ventricular Function in the Athlete's Heart: Combined Assessment by Speckle Tracking and Real Time Three-Dimensional Echocardiography

      Roberta Esposito, Maurizio Galderisi, Vincenzo Schiano-Lomoriello, Alessandro Santoro, Daniela De Palma, Renato Ippolito, Riccardo Muscariello, Ciro Santoro, Germano Guerra, Matteo Cameli, Sergio Mondillo and Giovanni De Simone

      Article first published online: 24 DEC 2013 | DOI: 10.1111/echo.12499

    18. Doppler-Derived Strain Imaging Detects Left Ventricular Systolic Dysfunction in Children with Turner Syndrome

      Fahrettin Oz, Ahmet Y. Cizgici, Ahmet Ucar, Ekrem B. Karaayvaz, Mehmet Kocaaga, Zehra Bugra, Fehmi Mercanoglu, Aytac Oncul, Kemal Nisli and Huseyin Oflaz

      Article first published online: 24 DEC 2013 | DOI: 10.1111/echo.12500

    19. Tissue Doppler–Derived Strain and Strain Rate during the First 28 Days of Life in Very Low Birth Weight Infants

      Sven Helfer, Lothar Schmitz, Christoph Bührer and Christoph Czernik

      Article first published online: 23 DEC 2013 | DOI: 10.1111/echo.12463

    20. Rationale and Design of a Randomized Trial Comparing Initial Stress Echocardiography versus Coronary CT Angiography in Low-to-Intermediate Risk Emergency Department Patients with Chest Pain

      Jeffrey M. Levsky, Linda B. Haramati, Cynthia C. Taub, Daniel M. Spevack, Mark A. Menegus, Mark I. Travin, Shayna Vega, Rikah Lerer, Durline Brown-Manhertz, Esther Hirschhorn, Jonathan N. Tobin and Mario J. Garcia

      Article first published online: 23 DEC 2013 | DOI: 10.1111/echo.12464

    21. Diagnostic Accuracy of Transesophageal Echocardiogram for the Detection of Patent Foramen Ovale: A Meta-Analysis

      M. K. Mojadidi, Nikolay Bogush, Jose Diego Caceres, Pavlos Msaouel and Jonathan Tobis

      Article first published online: 23 DEC 2013 | DOI: 10.1111/echo.12462

    22. Septal Curvature Is Marker of Hemodynamic, Anatomical, and Electromechanical Ventricular Interdependence in Patients with Pulmonary Arterial Hypertension

      Francois Haddad, Julien Guihaire, Mehdi Skhiri, Andre Y. Denault, Olaf Mercier, Shadi Al-Halabi, Bojan Vrtovec, Elie Fadel, Roham T. Zamanian and Ingela Schnittger

      Article first published online: 23 DEC 2013 | DOI: 10.1111/echo.12468


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