Cover image for Vol. 125 Issue 3

Edited By: E. Ralfkiær and B. Norrild

Impact Factor: 1.933

ISI Journal Citation Reports © Ranking: 2015: 37/79 (Pathology); 84/123 (Microbiology); 120/151 (Immunology)

Online ISSN: 1600-0463

Author Guidelines

Submit your manuscript online - visit APMIS Editorial Office

View online sample article and review.

The aim of APMIS is to publish papers reporting scientific studies within the fields of pathology, microbiology and immunology, and related areas of modern biomedicine. APMIS is published monthly and has subscribers worldwide. The journal is covered by Biological Abstracts/BIOSIS, ADONIS, Current Awareness in Biological Sciences/CABS, Science Citation Index, SCI-SEARCH, Research Alert, Medical Documentation Service, Current Contents: Life Sciences, CAB International. APMIS is an international journal and will accept papers from all over the world. It is published by the Scandinavian Societies for Pathology, Immunology and Microbiology, with a Scandinavian board of editors and consultants, and an international board of co-editors.

Publication Ethics
APMIS is a member of the Committee on Publication Ethics (COPE) and adheres to the ethical guidelines set fourth by COPE.


Copyright Transfer Agreement
If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions http://authorservices.wiley.com/bauthor/faqs_copyright.asp

For authors choosing OnlineOpen 
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://authorservices.wiley.com/bauthor/faqs_copyright.asp and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

 If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) or the Austrian Science Fund (FWF) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with your Funder requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement

PIthenticate lease note that APMIS uses a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.

Priority is given to original articles and reviews. Case reports will only be considered for publication if they serve to record significant new findings that may contribute to the clarification of rare diseases. Letters to the editor may include comments on articles published in APMIS or other original contributions of particular interest. Authors may be asked to rewrite a case report as a letter to the editor.

Articles exceeding 30 pages, as well as theses, monographs, etc., may be published as supplements on acceptance by the editorial board. The author bears the full cost. Further information is available from the editorial office.

All submitted manuscripts should have the language revised. Non-native speakers of English are encouraged to consider using one of the recommended language editing services here.

Online submission of manuscripts
Manuscripts should be submitted via http://www.manuscriptmanager.com/apmis. The text should be uploaded as a Microsoft Word file with tables and figures at the end of the document. If it is not possible to embed figures or tables, they should be uploaded as separate files. A pdf file may also be uploaded. Please note that docx files are compatible with the journal submission system.

Resubmitted (revised) manuscripts should also be sent in the above manner. High quality electronic versions of tables and figures will be required for publication.

The author alone is responsible for the views expressed in the article.

The author is responsible for the references.

REFEREES: Authors are requested to provide the names and full contact details of three suitably qualified referees. Wiley has training webinars, short videos, ethical guidelines, information on Publons, and step-by-step reviewer tips, which will be useful for both new and experienced referees. Please find the journal reviewer resources here.

Arrangement of manuscripts:
1. Title page
The title page should contain: A brief and concise title. Subtitles are to be preferred to long explanatory main titles. Name(s) of the author(s). Name(s) of the academic institution(s) or department(s) where the work was carried out, as well as the city and country. Telephone and fax numbers, and e-mail address. A running head of no more than 40 characters.

2. Summary
The summary should include: The author's(s') name(s) and initials, followed by the full title of the paper. The summary itself, which should be as brief as possible and not exceed 200 words. The aim, experimental design, main results and major conclusions should be presented. Key words (preferably no more than five). Name, address for correspondence, and e-mail address.

3. Text
* The introduction should state the reasons for initiating the study, and should present the problem briefly and concisely.

* Materials and methods. The materials and methods used should be described. The description must be brief and concise, but should include sufficient details to enable others to repeat the work. If a method has been described previously, bibliographical reference will suffice. Give a detailed description of control studies and experiments. Histological descriptions, reports of operations and autopsy findings should be condensed to include only relevant data.

* Results. The results obtained should be given in a brief and concise form. Reference should be made in the text to all tables and figures. The words Table and Figure must start with capital letters (e.g. Table 2, Fig. 3). The methods on which any statistical evaluation is based should be stated.

* Discussion (and Conclusion). The author's own results should be discussed and not just recapitulated. The results should be reviewed in relation to other works on the subject. Here a detailed analysis of previous literature would be appropriate. Unsolved problems or controversial results should be mentioned, but hypotheses should not be brought forward unless founded on facts in the text. The discussion may lead to a conclusion.

* Acknowledgements. Immediately after the text itself, general acknowledgements of help and support may be mentioned, e.g. thanks to foundations, other institutions or laboratory technicians. Personal thanks should not exceed 50 words.

4. References
References should be listed in the order of citation in the text (not alphabetically) and should follow the Vancouver system. Within the text, brackets (1), (2), (3–5) etc. should be used. It is recommended that authors use PubMed in conjunction with e.g. Reference Manager when compiling their references.


1. Standard journal article
Folkman J. Endogenous angiogenesis inhibitors. APMIS 2004;112:496-507.

Gradel KO, Dethlefsen C, Schønheyder HC, Nielsen H. Magnitude of bacteraemia is associated with increased mortality in non-typhoid salmonellosis: a one-year follow-up study. APMIS 2008;116:147-53.

2. More than six authors
Mylona E, Zarogiannos A, Nomikos A, Giannopoulou I, Nikolaou I, Zervas A, et al. Prognostic value of microsatellite instability determined by immunohistochemical staining of hMSH2 and hMSH6 in urothelial carcinoma of the bladder. APMIS 2008;116:59-65.

3. Organization as author
Diabetes Prevention Program Research Group. Hypertension, insulin, and proinsulin in participants with impaired glucose tolerance. Hypertension 2002;40:679-86. 4.

No author given
21st century heart solution may have a sting in the tail. BMJ 2002;325:184.

5. Chapter in a book
Strobl H, Platzer B, Jörgl A, Tashner S, Heinz L, Reisner P. Growth Factors. In: Handbook of Dendritic Cells: Biology, Diseases, and Therapies. Lutz MB, Romani N, Steinkasserer A, Steinman RM, editors. Weinheim: Wiley-VCH, 2006.

5. Tables and figures
Both tables and illustrations should be numbered with arabic numerals. Tables should be inserted after the text pages. All tables must have brief and concise headings. Explanations may be given below the tables. Figures should be made as self-explanatory as possible. Titles and detailed explanations belong in the legends, however, not on the illustrations themselves. Do not include more tables and illustrations than are absolutely necessary for proper documentation. Letters, numbers, and symbols on figures should be clear throughout, and of sufficient size that when reduced for publication each item will still be legible. Internal scale markers should be used. Symbols, arrows, or letters should contrast with the background. Electronic files of figures should be in a format (e.g. TIF or EPS) that will produce high quality images in the printed version of the journal.

File format
One separate TIFF file should be supplied for each illustration. The TIFF files (file extension .tif) should be in RGB mode or greyscale mode with no profile embedded and no layers. In order to achieve acceptable quality, illustrations must be printed at the following resolutions: Black and white and colour photos - 300 dpi; Graphs, drawings, etc. - 600 dpi; Combinations of photos and drawings (black and white and colour) – 600 dpi. If authors are not able to provide TIFF files, then EPS or PDF files (with no image quality reduction) are acceptable. Authors should make sure all submitted photographs are sharp.

Illustrations in APMIS are usually reproduced in one of three sizes: Full page width 155 mm (6.1 in); Medium width 110 mm (4.3 in); One column width 72 mm (2.8 in). Notwithstanding the requirements about resolution above, it will be detrimental to the quality of illustrations if the publisher has to scale up illustrations. Authors are therefore asked to supply illustrations at a final size suitable for the journal. For a colour photo to be reproduced at full page width, for example, the submitted material must have a width of about 1800 pixels (6.1 in * 300 dpi). APMIS reserves the right to decide, though, how large reproductions in the journal should be.

Authors should note that whereas most image capturing devises (digital cameras and scanners) operate in what is known as the RGB (Red, Green, Blue) colour space, the publishing process uses four colours, the CMYK (Cyan, Magenta, Yellow, Black) colour space. Illustrations supplied according to the above specifications (RGB mode) therefore have to be redefined in CMYK space for publishing. This will result in the more intense reds, greens and blues appearing duller. Authors are asked to make sure to adhere to the above specifications, and to review their illustrations critically before submitting. If possible, it is also a good idea for authors to view a CMYK transformed version of their illustration to avoid surprises in conversion, although if viewed on a screen or a home print out the results are not particularly trustworthy.

Further guidelines can also be found here.

Colour is reproduced free of charge.

Number of pages:
Generally, articles must not exceed 10 pages, including references, tables and illustrations. The editorial board reserves the right to condense the documentary material. In APMIS a standard page contains approximately 4800 units and, in petit, approximately 6200 units. If manuscripts exceed this standard format, a page charge of 134 Euros per additional page may be levied at the discretion of the editors. Case reports should not exceed 1500 words, corresponding to 2–3 pages in APMIS. Illustrations will only be accepted if considered indispensable. Letters should not exceed 750 words (no abstract), excluding figures, tables and references. Only 15 references and max 2 illustrations (figures or tables) are allowed.

Abbreviations and symbols
Avoid the abbreviation of ordinary words. If a long term appears often, the author may choose an abbreviation and explain this at its first occurrence. Avoid as far as possible unusual abbreviations. If such abbreviations are used, e.g. in tables, an explanation must be given in a footnote. There is no full stop after abbreviated units of measurement. See Chemical Abstracts. American Chemical Society, Washington DC, latest edition, and Units, Symbols and Abbreviations. The Royal Society of Medicine, London (Ellis G, editor), latest edition.

Chemical preparations
Commercial names, popular terms and abbreviations should not be used unless preceded by the proper chemical designation (e.g. according to Merck's Index). Any of these terms can then be used. Commercial names, if required, followed by registered name ®, must be capitalized. Latin binominals, which are to be written in italics, should be used in accordance with the International Code of Nomenclature of Bacteria, Virology, and the International Code of Zoological Nomenclature.

The corresponding author will receive a free PDF offprint of the article upon publication.