Immunological Reviews

Cover image for Vol. 259 Issue 1

Edited By: Gary Koretzky

Impact Factor: 12.155

ISI Journal Citation Reports © Ranking: 2012: 6/137 (Immunology)

Online ISSN: 1600-065X

Author Guidelines

Manuscripts should be submitted online at Full instructions and support are available on the site, and a user ID and password will be sent to you upon agreeing to contribute an article. Support can be contacted by phone (+1 434 817 2040 ext. 167) Monday-Friday, or at If you cannot submit online, please contact Justina Stadanlick in the Editorial Office by telephone (646 629 9484) or by e-mail (

Immunological Reviews does not accept unsolicited manuscripts.

A manuscript will be considered on the understanding that following invitation it has been submitted exclusively to Immunological Reviews, that the material presented has not been published before and is not under simultaneous consideration elsewhere.

Manuscript preparation
The preferred word-processing software for manuscript preparation is Word for Windows.

The first manuscript page (title page) should contain the title, authors' names, and all authors’ affiliations. The full postal address, telephone and fax number, and e-mail address of the corresponding author should be indicated.

The second manuscript page should contain the running title (not more than 45 characters), a 200-word summary of the article, and 3-6 keywords.

The articles should be 10000-14000 words (approximately 45 double spaced manuscript pages).

Make headings in normal uppercase and lowercase letters as they appear in the journal. Use one or two levels of headings. Make the first level of headings bold and the second level in normal letters

Separate words and sentences by one space only, made with the space bar.

Avoid emphasizing normal words. Italic has several specific purposes: for example, the Latin names of most plants and animals. Non-assimilated words from Latin or other languages should be italicized, e.g. in vivo, in vitro, per se, etc. Indicate italics with the italic feature of your program and not underlining. References to figures and tables in the text should be in italics: (Fig. 3, Table 1).

Number references in the order they appear in the text followed by those references that appear in the figure legends and tables.

Avoid using footnotes; incorporate points into the main text.

Unpublished data from sources not yet accepted for publication, including your own, should not be included in the list of references but may be referred to in the text as unpublished data or personal communications, including the source of data if relevant (for example, conference presentations).

In the Acknowledgments, state sources of grant support. Authors may include other appropriate acknowledgments (for example, to other scientists for their help or advice), but non-specific references to colleagues should be avoided (for example, apologizing to those whose word could not be cited due to space limitations). Authors are also responsible for disclosing all financial and personal relationships that could be viewed as presenting a potential conflict of interest. To prevent ambiguity, all authors must state explicitly whether potential conflicts do or do not exist. This information will be included on the title page of the published article.

Special characters and technical instructions
Use the correct characters in your character set for Greek letters and for mathematical and other symbols.

The Symbol font includes Greek and some mathematical characters and other symbols. Use the degree sign (ASCII code 161) when writing 37°C. Use  (beta) and not ß (German double 's'). Use µ (not in italics) for mu (and not u or u), as in µ (micron). Use the prime symbol (') for minute only in reporting angles and measurement of latitude and longitude; otherwise use 'min'. The prime symbol is a special symbol: ASCII code 162, Symbol font in word for Windows, Word for Macintosh and WordPerfect for Macintosh. For example, prime is used in adenosine 5'-triphosphate: not a single quotation mark (5’) or accent (5') or apostrophe (5').

Spell out numbers up to the number 10 and at the beginning of sentences; use Arabic numbers for figures and tables.

Use × for cross (multiplication sign and magnification) and not the letter x or X.

Use the ASM style manual as a guide for abbreviations and symbols. All units must be metric. Use 37°C, 3H, 14C, Min (for minutes), h (for hours), s (for seconds), ml and g; abbreviate liters as l in compound units such as g/l but '3 liters'. Use official or standardized nomenclature whenever available.

Spell out all abbreviations on first use. 

Place the references as a separate section at the end of the article.

Number citations in the text in the order of appearance in the text with Arabic numerals in parentheses:  'according to Jones & Brown (5, 6) and Smith et al. (10) '; 'following earlier work (1-4), we'.

Symbols are to be used as in original citation, e.g., Zhang S-Y, et al. Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of INF-α/β, IFN-γ, and IFN-λ in host defense. Immunol Rev 2008;226:29-40.

Abbreviate the titles of journals according to the List of Journals indexed printed annually in the January issue of Index Medicus/MEDLINE.

In each reference, list all authors except when there are seven or more, in which case only the first one should be given and ', et al.' added. References should be in Vancouver style as described in BMJ 1991;302:338-341. Examples of this style are the following:

Articles in journals
King LB, Monroe JG. Immunology. B cell receptor rehabilitation--pausing to reflect. Science 2001;291:1541-1544.

Books and other monographs
Personal author(s)

Colson JH, Armour WJ. Sports injuries and their treatment. 2nd rev edn. London: S Paul, 1986.

Chapter in a book
Weinstein L, Swartz MN. Pathologic properties of invading microorganisms. In: Sodeman WA Jr, Sodeman WA, eds. Pathologic physiology: mechanisms of disease. Philadelphia: Saunders, 1974:457-472.

Conference proceedings
Vivian VL, ed. Child abuse and neglect; 1984 Mar 30-31; Chicago. Chicago: American Medical Association, 1985.

Tables and figures
Use the facilities of your word processor to create tables. Save tables in a separate word processing file. Do not use a spreadsheet program.

Do not create lines above, within or below a table, as this makes it difficult to convert.

Footnotes in tables are indicated by letters a, b, c, d, etc., as superscripts and listed in separate rows at the bottom of the table. Insert one space between the footnote number and the subsequent text as shown below:
a This is the text for footnote a.
b This is the text for footnote b.

Number tables and figures with Arabic numerals in the order they appear, and give them brief explanatory titles. Extensive description of the table content should be given beneath the table.

Preferred file types for figures are TIFF and EPS. Detailed instructions for electronic artwork preparation may be found at

No charge is made for color illustrations.

Cover illustration
The front cover of each issue of the journal will contain a color illustration related to the topic of the issues. Authors are invited to submit illustrations for consideration for the cover.

Author material archive policy
Please note that unless specifically requested, Wiley-Blackwell will dispose of all hardcopy or electronic material submitted two volumes after publication. If you require the return of any material submitted, please inform the editorial office or production editor as soon as possible.

License Agreement
The author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For Authors Signing the Copyright Transfer Agreement
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For Authors Choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

Online Open
Online Open is available to authors who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With Online Open the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see

Corresponding authors will automatically receive a free PDF offprint by e-mail. Additional prints can be ordered on the offprint order form which accompanies the proof.