Immunological Reviews

Cover image for Vol. 280 Issue 1

Edited By: John Cambier

Impact Factor: 9.614

ISI Journal Citation Reports © Ranking: 2016: 10/151 (Immunology)

Online ISSN: 1600-065X

Podcasts


IMMUNOLOGICAL REVIEWS PODCASTS

Each volume of Immunological Reviews is devoted to a single topic of immunological research and is guest edited by a leading expert in that area. To further explore these unique volumes we are pleased to publish podcasts of interviews with the guest editors. Each podcast is free and available for you to view either from our YouTube channel or below.

NEW

Barton F. Haynes - Antibodies and Immunity to HIV-1

Barton F. Haynes introduces Antibodies and Immunity to HIV-1, edited by Barton F. Haynes (Duke Human Vaccine Institute, Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC, USA) and Dr. John R. Mascola (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA).
This issue features a series of reviews covering B cells and Immunity to HIV.
Click here to watch (2 mins 10 secs).
Click here to view the full list of review articles being discussed.


Dr. Carl Nathan - Tuberculosis

In this interview, Carl Nathan, Chairman of the Department of Microbiology and Immunology, the R.A. Rees Pritchett Professor of Microbiolog, and the Director of the Abby and Howard P. Milstein Program in Translational Medicine at Weill Cornell Medical College, discusses tuberculosis. He shares his insights on why this disease is such a huge public health problem and discusses what investigators are doing to better understand the biology and pathogenesis of this bacterial infection. Dr. Nathan offers his views on how better treatments for this disease can be discovered, and he gives an overview of the topics covered in Volume 264 of Immunological Reviews.

Click here to watch. (16 mins 3 secs) Interview by Justina Stadanlick
Click here to view the full list of review articles being discussed

Dr. Carl June - Adoptive Immunotherapy for Cancer

In this interview, Carl June, the Richard M. Vague Professor of Immunotherapy in the Department of Pathology and Laboratory Medicine and the Director of Translational Research at the Abramson Family Cancer Research Institute at the University of Pennsylvania, discusses adoptive immunotherapy for cancer. Dr. June informs us about the history of the field and describes the exciting new applications that are successfully treating cancer patients today. Dr. June also gives a overview of the topics covered by the reviews in Volume 257 of Immunological Reviews.
Click here to watch. (12 mins 53 secs) Interview by Justina Stadanlick
Click here to view the full list of review articles being discussed

Cell:Cell Contacts

In this interview, Facundo Batista, Group Leader in the Lymphocyte Interaction Laboratory at Cancer Research UK London Research Institute,discusses cell:cell interactions in the immune system. Dr. Batista informs us about how studies of cellular and molecular interactions have been enhanced through advances in imaging technologies. He also discusses the ongoing innovative work in his laboratory as well as the topics covered in Volume 251 of Immunological Reviews.
Click here to watch. (15 mins 25 secs) Interview by Justina Stadanlick
Click here to view the full list of review articles being discussed.

NF-kB

In this interview, Sankar Ghosh, the Hutt & Silverstein Family Professor and Chair of the Department of Microbiology & Immunology at Columbia University, discusses NF-kB. Dr. Ghosh informs us about how this important transcription factor was identified 25 years ago and the stories behind the many discoveries that have followed. He also speculates on what the next 25 years of research may bring. His personal perspectives and those of other key investigators in this field are covered in more detail in Volume 246 of Immunological Reviews.

Click here to watch. (24 mins 36 secs) Interview by Justina Stadanlick
Click here to view the full list of review articles being discussed.

Mechanisms of Tolerance

In this interview, Jeffrey Bluestone, the AW and Mary Margaret Clausen Distinguished Professor and Executive Vice Chancellor and Provost of the University of California, San Francisco, discusses immune tolerance. Beginning with how Dr. Bluestone has seen this field develop over the past 30 years, he highlights some of the seminal discoveries in understanding the complexities of immune tolerance as well as speculates where the major discoveries, particularly as they apply to human immunology, will be made next. Many of the discoveries and clinical applications discussed are covered in more detail in Volume 241 of Immunological Reviews.
Click here to watch. (20 mins 35 secs) Interview by Justina Stadanlick
Click here to view the full list of review articles being discussed.

Dendritic Cell Subsets
In this interview, Dr. Ralph Steinman, Henry G. Kunkel Professor and Senior Physician at the Rockefeller University, discusses dendritic cell research, beginning with the studies that led to his discovery of these cells in 1973.
The major finding that dendritic cells, not macrophages, are the primary antigen-presenting cell in the body is discussed, as well as some subsequent surprising findings made by investigators around the world studying this essential immune cell lineage. He offers insights into the direction of future dendritic cell research and closes by giving us an overview of volume 234, which covers the newest discoveries related to Dendritic Cell Subsets.
Click here to watch. (15 mins 16 secs) Interview by Justina Stadanlick
Click here to view the full list of review articles being discussed.

Mechanisms of Costimulation
In this volume Dr. Arlene Sharpe, Professor of Pathology at Harvard Medical School, addresses the key topic of costimulation in the immune system.
For decades it has been known that engagement of immunoreceptors on both B and T lymphocytes is insufficient to elicit a productive immune response. Dr. Arlene Sharpe has assembled many of the individuals who have made the most seminal findings that have informed the immunology community about our current understanding of how costimulation functions to enhance or repress immune system activation.
Click here to listen. (13 mins, 18 secs) Interview by Wendy Barnaby
Click here to view the full list of review articles being discussed.

Kinases and Phosphates of the Immune System
In this volume Dr. Arthur Weiss, an Investigator of the Howard Hughes Medical Institute, examines the complex biology of kinases and phosphatases as these enzymes positively and negatively regulate immune cell responses. The contributors to this issue include investigators who have provided the most compelling evidence for the mechanisms by which protein phosphorylation and dephosphorylation exert exquisite control of key pathways in cells of both the adaptive and innate immune systems.
Click here to listen. (14 mins, 58 secs) Interview by Wendy Barnaby
Click here to view the full list of review articles being discussed.

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