Cover image for Vol. 18 Issue 5

Edited By: Michael S. Marks, Trina A. Schroer, Robert G. Parton and Sharon A. Tooze

Online ISSN: 1600-0854

Author Guidelines


Link to: Public Access Policy

Aim and Scope of Traffic
Effective with the 2014 volume, Traffic will be published in an online-only format. Print subscription and single issue sales are available from Wiley’s Print-on-Demand Partner. To order online, click through to the ordering portal form on the journal’s subscribe and renew page on WOL.

encourages and facilitates the publication of papers covering the cell biology of intracellular transport in health and disease. Areas of interest include protein, nucleic acid and lipid traffic, molecular motors, intracellular pathogens, intracellular proteolysis, nuclear import and export, cytokinesis and the cell cycle, protein translocation, antigen processing and presentation, organelle biogenesis, cell polarity and organization, and organelle movement.

All aspects of the structural, molecular biology, biochemistry, genetics, morphology, intracellular signaling and relationship to hereditary or infectious diseases will be covered. Manuscripts must provide a clear conceptual or mechanistic advance. The editors will reject papers that require major changes, including addition of significant experimental data or other significant revision.

Traffic will consider manuscripts of any length, but encourages authors to limit their papers to 16 typeset pages or less.

Submission of Articles
All articles should be submitted online at Full instructions for submitting the manuscript are provided on the submission site. Please contact the Editorial Office (see below) or the helpline (directions to contact helpline are provided online) for any concerns or problems.

Traffic Editorial Office
Lisa A. Hannan, Ph.D., Managing Editor
1042 N. El Camino Real Ste B-512
Encinitas, CA 92024
Phone: +1 (760) 652 5804
Fax: +1 (760) 683 3227

Authors must provide a letter of permission for any personal communication, and permission from the copyright holder for the use of any material previously published. Authors must suggest potential reviewers and can identify persons to be excluded as reviewers for professional reasons at the time of initial submission. Traffic expects that all authors will conform to the National Science Advisory Board for Biosecurity (NSABB) guidelines for Dual Use Life Sciences Research’.

Format of Articles
Manuscripts should be formatted to appear similar to a final typeset manuscript. Specifically, univers-light or arial are the preferred font for text and figures, the title (12 point font) and authors (10 point font) should fit across the full width of the first page, and the remaining text (9 point font) arranged in two columns. The document should be single spaced. The figures and supplemental figures should follow the text.

All original submissions should be submitted as a single PDF file that is no more than 15MB in size. This file must include: the manuscript text (including the tables and figure legends and legends for the supplemental materials) and all figures and supplemental materials (excluding movies). The figures should be formatted to fit on a full page, include the figure number and should be provided at 200-300 dpi resolution. JPEG files tend to be smaller and can be more easily incorporated into the single document than TIFF or EPS files.

Pre-submission English-Language Editing
Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found here. All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

Preparation of Figures
Images cannot be modified to change the overall appearance or appearance of any specific feature. Adjustments of brightness and contrast or color balance are acceptable but must be applied to the entire image. Features cannot be obscured and any rearrangements must be explicitly indicated by the insertion of dividing lines. All images will be examined for any indication of improper modifications. The final acceptance of all manuscripts is contingent on any concerns raised in our review of the figures being resolved.

Organization of Research Articles

  • Title must be concise and contain no more than 100 characters including spaces. The title page should include a running title of no more than 50 characters, 5–10 key words, complete names and institutions for each author, and the name, address, phone number, fax number and e-mail address for the corresponding author.
  • Synopsis and Graphical Table of Contents Traffic’s table of contents will include a brief (no more than 80 words) synopsis statement that describes the most significant findings in the study. Please include this on the cover page of the submitted paper.
    In addition, authors are encouraged to include an image to be included in the Table of Contents. It is recommended that this image present a unifying model that takes into account the results presented in the paper. The image should be supplied as a 300 dpi jpeg, tif or a pdf file that fits within one column (8cm wide) and is fully legible at this size. 8pt Trade Gothic is the recommended font (8 pt Arial or Myriad can be used as an alternative).
  • Abbreviations and nomenclature - Traffic adheres to the conventions outlined in Units, Symbols and Abbreviations: A guide for medical and scientific editors and authors. Non-standard abbreviations must be used 3 or more times and written in full when first used. Standard genetic nomenclature should be used. Proteins tagged at the N- or C- terminus should be named such that the placement of the tag name corresponds to the location of the tag in the fusion protein (for N-terminal tagged proteins the tag name comes first, eg. GFP-ARFGAP). Authors are cautioned to use the full name of the fusion protein throughout the manuscript to avoid confusion.
  • Abstract is limited to 200 words. References must be cited in full.
  • Introduction should be focused; exhaustive literature reviews are not appropriate.
  • Results and Discussion can be combined (particularly for short communications) or can be written as separate sections.
  • Materials and Methods must contain sufficient detail such that, in combination with the references cited, all experiments reported can be fully reproduced. All experiments using either experimental animals or human subjects must be approved by the appropriate review boards of the host institution. For experiments using experimental animals, a statement clearly indicating that appropriate measures were taken to reduce the pain or discomfort of experimental animals must be included in the Materials and Methods. For studies involving the use of human subjects, the Materials and Methods must indicate that the studies were performed according to the principles outlined by the Helsinki Declaration, and that appropriate informed consent was obtained.
  • Acknowledgments - All sources of institutional, private and corporate financial support for the work within the manuscript must be fully acknowledged, and any potential conflicts of interest noted.
  • References All references should be numbered consecutively in order of appearance and should be as complete as possible. In text citations should cite references in consecutive order using Arabic superscript numerals. Sample references follow:
    Journal Article
    1. King VM, Armstrong DM, Apps R, Trott JR. Numerical aspects of pontine, lateral reticular, and inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp Neurol 1998;390:537-551.
    Voet D, Voet JG. Biochemistry. New York: John Wiley & Sons; 1990. 1223 p.
    Please note that journal title abbreviations should conform to the practices of Chemical Abstracts.
    For more information about AMA reference style - AMA Manual of Style
  • Figures should be planned to fit into 1, 1.5 or 2 column widths, and text sufficiently large to be easily visible in the reproduced manuscript. For the benefit of colorblind individuals we suggest two color images should be presented as magenta and green, and images with three or more colors should be presented as individual panels.
  • Figure Legends and Tables should be a separate section of the manuscript. Tables should be double-spaced with no vertical rulings, with a single bold ruling beneath the column titles. Units of measure must be included in the column title.
  • Supporting Information. All supplemental figures, movies, text and tables must be absolutely required for fully understanding the manuscript. Each item cannot exceed 5MB. Only 5 supplemental figures can be accepted. Preliminary data that is not essential for understanding the paper will not be accepted as supplemental material. Please provide a list of all supplemental material submitted that includes (1) an indication of what figure or table it is associated with in the main text (2) and a short explanation of its significance for the paper. These can be a useful way for an author to include important but ancillary information with the online version of an article. Examples of Supporting Information include additional tables, data sets, figures, movie files, audio clips, 3D structures, and other related nonessential multimedia files. Supporting Information should be cited within the article text, and a descriptive legend should be included. It is published as supplied by the author, and a proof is not made available prior to publication; for these reasons, authors should provide any Supporting Information in the desired final format. For further information on recommended file types and requirements for submission, please visit:

Review Articles, Toolbox, Case Report, Transit Authority, Traffic Interchange and Traffic Report Articles
Traffic welcomes proposals for alternative types of articles or correspondence in the following categories:

  • Reviews should be focused, represent a critical and balanced view of the field.
  • Toolboxes are either a methodological resource/review or a general reference database. They should compile information or review methodological advances.
  • Transit Authorities are brief commentaries of interest to the readership of Traffic, and can be up to 1500 words long.
  • Traffic Interchanges are brief communications suggesting new conceptual insights or directions for future research, and can include new or recently published data. Topics to be covered can include, but are not limited to, genome analysis, new hypotheses or integration of diverse areas.
  • Traffic Reports are meeting reports, and can be up to 1500 words long.
  • Case Reports are original research articles on clinical cases relevant to intracellular transport.

Transparent Review Process
Beginning January 1, 2016, Traffic will publish the editorial correspondence related to the review of accepted papers as supplemental material online. This includes the decision letter(s), referee comments and author rebuttals. Referee identities and confidential comments to the editor will remain confidential.

Cover Submissions
Authors are encouraged to submit original micrographs, molecular structures or graphic art for consideration as cover art. Submission of cover art is not limited to authors. Black and white or color images can be submitted, should be trimmed to fit into the photograph area of the cover (21 cm wide, 24 cm high, 300 dpi or higher resolution), supplied at full size and accompanied by a cover legend. Pictures accepted for covers will be exclusively licensed, and will be made available in the Traffic web site photo gallery.

Accepted Manuscripts
Final submission of manuscripts must include the Word document for all text and tables, including legends for the supplemental materials. Figures must be provided as individual JPEG, TIFF or EPS files of at least 300 dpi resolution. Directions for formatting of the final documents will be provided prior to acceptance.

Distribution of Materials
All materials described in the paper, including strains, clones or antibodies, will be made available to the academic scientific community. Nucleic acid and amino acid sequences, as well as X-ray crystallographic data, must be deposited and made accessible in the appropriate database. Nucleotide sequence data can be submitted in electronic form to any of the three major collaborative databases: DDBJ/EMBL/GenBank. It is only necessary to submit to one database.

Duplicate Publication and Scientific Fraud
In cases of suspected scientific misconduct (fabrication or falsification of data, double submission or publication, or plagiarism), the editors will attempt to clarify the matter with the authors. Should that fail to resolve the situation satisfactorily, the editors will contact the institution and/or funding body of the corresponding author to request that they initiate a formal investigation into possible scientific misconduct. Traffic will not consider publication of any papers by the offending authors for a period of 5 years. Traffic employs a plagiarism detection system. By submitting your manuscript to Traffic you accept that your manuscript may be screened for plagiarism against previously published works.

Copyright Transfer Agreement
Authors submitting a paper do so on the understanding that the work has not been published before, is not being considered for publication elsewhere, and has been read and approved by all of the authors. If and when a manuscript or cover art is accepted for publication in Traffic, authors must agree to sign a Copyright Transfer Agreement (CTA). Signature of the CTA is a condition of publication and papers will not be passed to the publisher for production unless a signed form has been received. (Government employees need to complete the Author Warranty sections). After submission authors will retain the right to publish their paper in various medium/circumstances (please see the form for further details). The appropriate form will be supplied by the editorial office. Alternatively, authors may like to download a copy of the form here. Please return your completed form to: Lisa Hannan, 1042 N. El Camino Real Ste B-313, Encinitas, CA 92024. Alternatively, a scanned version of the form can be emailed to, or faxed to +1 (760) 683 3227.

Accepted Articles
'Accepted Articles' have been accepted for publication and undergone full peer review but have not been through the copyediting, typesetting, pagination and proofreading process. Accepted Articles are published online a few days after final acceptance, appear in PDF format only (without the accompanying full-text HTML) and are given a Digital Object Identifier (DOI), which allows them to be cited and tracked. The DOI remains unique to a given article in perpetuity. More information about DOIs can be found online at Given that Accepted Articles are not considered to be final, please note that changes will be made to an article after Accepted Article online publication, which may lead to differences between this version and the Version of Record.

The Accepted Articles service has been designed to ensure the earliest possible circulation of research papers after acceptance. Given that copyright licensing is a condition of publication, a completed copyright form is required before a manuscript can be processed as an Accepted Article.

Accepted articles will be indexed by PubMed; therefore the submitting author must carefully check the names and affiliations of all authors provided in the cover page of the manuscript, as it will not be possible to alter these once a paper is made available online in Accepted Article format. Subsequently the final copyedited and proofed articles will appear either as Early View articles in a matter of weeks or in an issue on Wiley.

Traffic is covered by John Wiley & Sons' Early View service
Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors' final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. The nature of Early View articles means that they do not yet have volume, issue or page numbers, so Early View articles should be cited using its DOI.

Open Access
If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

Page Proofs
The corresponding author will receive an email alert containing a link to a web site. A working e-mail address must therefore be provided for the corresponding author. The proof can be downloaded as a PDF (portable document format) file from this site. Acrobat Reader 7.0 will be required in order to read and correct this file on the screen. Further instructions will be sent with the proof. Excessive changes made by the author in the proofs, excluding typesetting errors, will be charged separately.

Publication Charges
Upon acceptance of an original research manuscript the authors will be charged publication charges according to the schedule below. Publication charges are $140 for each typeset page from pages 1-10 inclusive, and $200 for each subsequent typeset page above 10 pages. Each typeset page can be roughly estimated to contain approximately 750 words. There are no charges for color figures. To download a copy of the publication charge form, click here.

Free access to the final PDF offprint of your article will be available via author services only. Please therefore sign up for author services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers.
Paper offprints of the printed published article may be purchased if ordered via the method stipulated on the instructions that will accompany the proofs. Printed offprints are posted to the correspondence address given for the paper unless a different address is specified when ordered. Note that it is not uncommon for the printed offprints to take up to 8 weeks to arrive after publication of the journal. For further information please contact C.O.S. Printers Pte Ltd, 9 Kian Teck Crescent, Singapore 628875; Fax: 65 6265 9074; E-mail:

Public Access Compliance
In full compliance with all public access requirements (NIH, HHMI, Wellcome Trust, Research Councils UK (eg. MRC, BBSRC)), Traffic submits accepted manuscripts that have been funded by the agencies above to PubMedCentral and PubMedCentralUK. The authors will receive confirmation and further instructions directly from PubMedCentral.

From April 2008, the NIH mandated grantees to deposit their peer-reviewed author manuscripts in PubMed Central, to be made publicly available within 12 months of publication. The NIH mandate applies to all articles based on research that has been wholly or partially funded by the NIH and that are accepted for publication on or after April 7, 2008. In order to help authors comply with the NIH mandate, for papers accepted for publication in Traffic after this date Wiley Blackwell will post the accepted manuscript (incorporating all amendments made during peer review, but prior to the publisher’s copy-editing and typesetting) of articles by NIH grant-holders to PubMed Central at the point of acceptance by the journal. This version will then be made publicly available in PubMed Central 12 months after publication. Following the deposit Wiley Blackwell authors will receive further communications from the NIH with respect to the submission. For further information, see here.