American Journal of Transplantation

Cover image for Vol. 15 Issue 8

Edited By: Allan D. Kirk

Impact Factor: 5.683

ISI Journal Citation Reports © Ranking: 2014: 2/25 (Transplantation); 4/198 (Surgery)

Online ISSN: 1600-6143

Images in Transplantation (CME)

  • A Surprising Renal Graft Doppler Ultrasound in a Kidney–Heart Transplant Recipient: When Hemodynamic Analysis Is Even More Informative Than Usual

    A Surprising Renal Graft Doppler Ultrasound in a Kidney–Heart Transplant Recipient: When Hemodynamic Analysis Is Even More Informative Than Usual

    Doppler ultrasound of the renal graft on postoperative day 21. Color and pulsed wave Doppler of an interlobar artery during inspiration (red dots) and expiration (green dots). Cross 1 measures the arterial systolic peak velocity, and cross 2 measures the end diastolic velocity. Resistive indices are normal on expiration at 0.70, and severely increased on inspiration at 1 (due to the disappearance of the antegrade diastolic flow). These variations were not secondary to patient's motion.

  • Fever of Unknown Origin in a Kidney Transplant Recipient

    Fever of Unknown Origin in a Kidney Transplant Recipient

    Limited noncontrast CT of the chest showing bilateral ground-glass infiltrates.

  • Persistent Ascites, Leg Edema and Renal Dysfunction After Liver Transplant

    Persistent Ascites, Leg Edema and Renal Dysfunction After Liver Transplant

    Initial venogram of inferior vena cava. Arrow indicates area of concern.

  • Fatal Infectious Pulmonary Complications Post-Deceased Donor Renal Transplantation

    Fatal Infectious Pulmonary Complications Post-Deceased Donor Renal Transplantation

    (A) Anterior–posterior chest X-ray on presentation demonstrated a large 13 cm cavity in the right hemithorax likely representing a large lung abscess. An empyema is also in the differential, but would be considered less likely. (B) Coronal image from a CT performed on admission demonstrating a large focus of infection involving the right lower lobe with extension into the right pleural space and chest wall via a bronchopleural fi stula.

  • A Rare Anomaly in the Donor Vena Cava

    A Rare Anomaly in the Donor Vena Cava

    An inferior vena cava web is identified during surgery in a live patient.

  • An Unusual Case of Ischemic Nephropathy

    An Unusual Case of Ischemic Nephropathy

    Abdominal CT scan without contrast.

  • Early Graft Dysfunction After Lung Transplantation

    Early Graft Dysfunction After Lung Transplantation

    CXR 6 h after bilateral LTx demonstrating dense pulmonary infiltrates.

  • Lung Mass in a Kidney Transplant Recipient

    Lung Mass in a Kidney Transplant Recipient

    Left lower lobe opacity.

  • A Surprising Renal Graft Doppler Ultrasound in a Kidney–Heart Transplant Recipient: When Hemodynamic Analysis Is Even More Informative Than Usual
  • Fever of Unknown Origin in a Kidney Transplant Recipient
  • Persistent Ascites, Leg Edema and Renal Dysfunction After Liver Transplant
  • Fatal Infectious Pulmonary Complications Post-Deceased Donor Renal Transplantation
  • A Rare Anomaly in the Donor Vena Cava
  • An Unusual Case of Ischemic Nephropathy
  • Early Graft Dysfunction After Lung Transplantation
  • Lung Mass in a Kidney Transplant Recipient

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Current Issue Highlights

HIV and organ transplantation each emerged as significant disruptive forces in healthcare in the 1980s. Our rudimentary understanding of both led us to draw boundaries around their management that have, with time, been erased, as their perceived mutual exclusivity has given way to an appreciation that transplantation can be an important therapeutic modality in many HIV-related comorbidities. This month, we highlight articles relevant to the HIV Organ Policy Equity (HOPE) act, new legislation permitting HIV+ donors to donate organs to HIV+ recipients. “The AJT Report” covers practitioner perspectives of this new law, and Boyarsky et al review clinical decision issues relevant to HIV+ to HIV+ transplantation. Articles by Locke et al and Richterman et al report new data on the management of HIV+ recipients and the prevalence of HIV+ donors, respectively. Also, be sure to check out the new AST/AJT online journal club taking place Monday, August 31, at 4:00 pm ET. Participation is free to all; register at myAST.org/journalclub. Cover design by Ken North, North Design Group.

Read the Editor's picks of the month:

Challenges and Clinical Decision-Making in HIV-to-HIV Transplantation: Insights From the HIV Literature
B. J. Boyarsky, C. M. Durand, F. J. Palella Jr. and D. L. Segev

Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected Recipients
J. E. Locke, R. D. Reed, S. G. Mehta, C. Durand, R. B. Mannon, P. MacLennan, B. Shelton, M. Y. Martin, H. Qu, R. Shewchuk and D. L. Segev

An Assessment of HIV-Infected Patients Dying in Care for Deceased Organ Donation in a United States Urban Center
A. Richterman, D. Sawinski, P. P. Reese, D. H. Lee, H. Clauss, R. D. Hasz, A. Thomasson, D. S. Goldberg, P. L. Abt, K. A. Forde, R. D. Bloom, S. L. Doll, K. A. Brady and E. A. Blumberg

An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA
K. A. Thomas, N. M. Valenzuela, D. Gjertson, A. Mulder, M. C. Fishbein, G. C. Parry, S. Panicker and E. F. Reed

Role of Sphingosine-1-Phosphate in Transplant Vasculopathy Evoked by Anti-HLA Antibody
M. Trayssac, S. Galvani, N. Augé, R. Sabbadini, D. Calise, E. Mucher, F. Sallusto, M. Thomsen, R. Salvayre and A. Nègre-Salvayre

The Impact of Hydroxyethyl Starch Use in Deceased Organ Donors on the Development of Delayed Graft Function in Kidney Transplant Recipients: A Propensity-Adjusted Analysis
M. S. Patel, C. U. Niemann, M. B. Sally, S. De La Cruz, J. Zatarain, T. Ewing, M. Crutchfield, C. K. Enestvedt and D. J. Malinoski

The AJT Report

AJT Report August 2015After more than 20 years of discarding HIV-positive organs, physicians in the United States now have an opportunity to provide transplantation to hundreds of HIV-positive individuals each year. We look at how the transplantation community now approaches HIV and what challenges remain. Also in this issue, new research finds common ground between transplant immunosuppression and HIV immunology.


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Watch the Latest Video in the AJT Video Library:

RIPK3-Mediated Necroptosis Regulates Cardiac Allograft Rejection
A. Pavlosky, A. Lau, Y. Su, D. Lian, X. Huang, Z. Yin, A. Haig, A.M. Jevnikar and Z.-X. Zhang.
Published online: Jul 2014

A video abstract for the article entitled RIPK3-Mediated Necroptosis Regulates Cardiac Allograft Rejection.

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