American Journal of Transplantation

Cover image for Vol. 16 Issue 7

Edited By: Allan D. Kirk

Impact Factor: 5.669

ISI Journal Citation Reports © Ranking: 2015: 2/25 (Transplantation); 4/199 (Surgery)

Online ISSN: 1600-6143

Images in Transplantation (CME)

  • New-Onset Seizures 15 Years After Renal Transplan

    New-Onset Seizures 15 Years After Renal Transplan

    Cranial CT showing bilateral frontal chronic collections, with no apparent parenchymal findings.

  • Fever, Cough, and Right Lower Quadrant Abdominal Pain in a Liver Transplant Recipient

    Fever, Cough, and Right Lower Quadrant Abdominal Pain in a Liver Transplant Recipient

    (Left) Computed tomography (CT) of abdomen/pelvis with inflammatory changes, including necrotic lymph nodes and small abscess in right lower quadrant. (Right) CT of thorax with multifocal pneumonia and left upper lobe consolidation.

  • Intracaval Mass Discovered at the Time of Liver Procurement

    Intracaval Mass Discovered at the Time of Liver Procurement

    (A) Mass encountered in the inferior vena cava of a donor liver allograft. (B) Demonstration of the mobility and attachment of the mass to the wall of the inferior vena cava.

  • Fatal Complication of Recent Liver Transplant

    Fatal Complication of Recent Liver Transplant

    Maculopapular rash. The rash was also present on the chest, abdomen, bilateral thighs, and upper extremities.

  • Critical Incidental Ultrasound Finding in the Postoperative Renal Transplant Patient

    Critical Incidental Ultrasound Finding in the Postoperative Renal Transplant Patient

    Doppler ultrasonography of the renal allograft.

  • Chest Wall Mass 5 Years After Liver Transplantation

    Chest Wall Mass 5 Years After Liver Transplantation

    : Chest wall mass on patient.

  • Successful Liver Retrieval After Acute Aortic Dissection Involving the Celiac Artery Origin

    Successful Liver Retrieval After Acute Aortic Dissection Involving the Celiac Artery Origin

    (A) Preoperative CT image showing the affected origin of the celiac artery (CA). However, arterial enhancement is seen beyond the celiac artery origin and in all the intrahepatic arterial branches. The true lumen (arrow) and the false lumen (*) are shown, separated by an intimal flap. (B) Reconstructed image of the entire aorta demonstrating the dissected CA and the left renal artery (RA). The superior mesenteric artery (SMA) and the right RA are patent.

  • 52-Year-Old Male With Upper Lobe Predominant Cystic Lung Disease Requiring Bilateral Lung Transplantation

    52-Year-Old Male With Upper Lobe Predominant Cystic Lung Disease Requiring Bilateral Lung Transplantation

    Chest computed tomography 2 months prior to transplant.

  • New-Onset Seizures 15 Years After Renal Transplan
  • Fever, Cough, and Right Lower Quadrant Abdominal Pain in a Liver Transplant Recipient
  • Intracaval Mass Discovered at the Time of Liver Procurement
  • Fatal Complication of Recent Liver Transplant
  • Critical Incidental Ultrasound Finding in the Postoperative Renal Transplant Patient
  • Chest Wall Mass 5 Years After Liver Transplantation
  • Successful Liver Retrieval After Acute Aortic Dissection Involving the Celiac Artery Origin
  • 52-Year-Old Male With Upper Lobe Predominant Cystic Lung Disease Requiring Bilateral Lung Transplantation

Recently Published Issues

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Current Issue Highlights

Transplantation chimerism refers to the coexistence of cells or tissues from two individuals within one recipient. All transplant patients are chimeras of sorts, with the allograft being of donor origin, but this degree of chimerism clearly does not lead to allograft tolerance. However, numerous studies have shown that augmenting the degree of chimerism (e.g. creating a state of mixed bone marrow chimerism) can lead to a state of tolerance, albeit with substantial risks related to donor bone marrow infusion. This month, we report two articles (Hu et al and Cameron et al) showing that mobilization of recipient stem cells using a CXCR4 antagonist facilitates their engraftment within the donor organ, and in doing so creates a chimeric organ that can be maintained without immunosuppression. This novel take on the chimerism model of tolerance is intriguing for its simplicity and potential broad applicability, and is certainly worthy of attention.



Editor's Picks

Gene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms That Correlate With Worse Long-Term Outcomes
Modena et al

Hidden Inflammatory Molecular Signatures in Graft Kidney Biopsies: Silent Markers of Graft Fate?
Maluf et al

Regulatory T Cell Infusion Can Enhance Memory T Cell and Alloantibody Responses in Lymphodepleted Nonhuman Primate Heart Allograft Recipients
Ezzelarab et al

Regulating T Cell Behavior
Knechtle and Fairchild

Chimeric Allografts Induced by Short-Term Treatment With Stem Cell–Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: A Study in Rats
Hu et al

Chimeric Allografts Induced by Short-Term Treatment With Stem Cell Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: II, Study in Miniature Swine
Cameron et al

A Risk Index for Living Donor Kidney Transplantation
Massie et al

Living Kidney Donor Profile Index: Utility and Limitations
Schold and Kaplan

Featured Video

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AJT Supporting Information Videos

Rapid Restoration of Vascularity and Oxygenation in Mouse and Human Islets Transplanted to Omentum May Contribute to Their Superior Function Compared to Intraportally Transplanted Islets
D. Espes, J. Lau, M. Quach, S. Ullsten, G. Christoffersson, and P.O. Carlsson
Published online: June 2016


Video S1: Real-time in vivo confocal imaging of functional blood falow in mouse islets transplanted to the omentum 14-days posttransplantation. The islets express green fluorescent protein and the blood flow and vasculature (red) were visualized using intraarterially injected rhodamine-dextran. Imaging was performed using a Zeiss Plan-Apo 40×/1.0 W objective on a Zeiss 5 Live line-scanning confocal microscope..

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AJT Report

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Mind The Gap

Currently, very few institutions offer formal training programs for ancillary transplant staff, such as administrators, coordinators and procurement staff. In this issue of “The AJT Report,” we review the few existing programs available and explore what this gap in training may mean for the future of the transplantation workforce. Also in this issue, we look at a new NIH program designed to address disparities in surgical care, as well as the results of a study demonstrating a new combination treatment for patients with hepatitis C.


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