American Journal of Transplantation

Cover image for Vol. 17 Issue 8

Edited By: Allan D. Kirk

Impact Factor: 6.165

ISI Journal Citation Reports © Ranking: 2016: 2/25 (Transplantation); 5/196 (Surgery)

Online ISSN: 1600-6143

Images in Transplantation (CME)

  • Rare Late Complication After Percutaneous Liver Biopsy

    Rare Late Complication After Percutaneous Liver Biopsy

    Abdominal computed tomography (CT) scan (upper images) and sonography (lower images) on the day of admittance.

  • Human Papillomavirus Manifestation After Kidney–Pancreas Transplantation

    Human Papillomavirus Manifestation After Kidney–Pancreas Transplantation

    Presenting lesions, anterior view.

  • Fever in a Kidney Transplant Recipient

    Fever in a Kidney Transplant Recipient

    Computed tomography (CT) of the abdomen with wedge-shaped hypodensities.

  • Confusion and Seizures in a Stem Cell Transplant Recipient

    Confusion and Seizures in a Stem Cell Transplant Recipient

    Axial fluid–attenuated inversion recovery magnetic resonance image.

  • Ureteral Obstruction and New Groin Pain in a Kidney Transplant Recipient

    Ureteral Obstruction and New Groin Pain in a Kidney Transplant Recipient

    (A) Ultrasound of renal transplant on initial presentation. (B) Coronal computed tomography on initial presentation. (C) Percutaneous nephrostomy placement with antegrade nephrostogram.

  • Pulmonary Nodules in a Kidney Transplant Recipient

    Pulmonary Nodules in a Kidney Transplant Recipient

    Noncontrast computed tomography of the chest showing innumerable pulmonary nodules.

  • Painful Groin Mass in a Liver Transplant Recipient

    Painful Groin Mass in a Liver Transplant Recipient

    Computed tomography of the abdomen and pelvis demonstrating a hyperattenuating mass in the left inguinal canal.

  • Arterial Thrombus in a Heart Transplant Recipient

    Arterial Thrombus in a Heart Transplant Recipient

    Doppler imaging of the lower extremity. Acute thrombus is demonstrated in the left popliteal artery (arrow).

  • Rare Late Complication After Percutaneous Liver Biopsy
  • Human Papillomavirus Manifestation After Kidney–Pancreas Transplantation
  • Fever in a Kidney Transplant Recipient
  • Confusion and Seizures in a Stem Cell Transplant Recipient
  • Ureteral Obstruction and New Groin Pain in a Kidney Transplant Recipient
  • Pulmonary Nodules in a Kidney Transplant Recipient
  • Painful Groin Mass in a Liver Transplant Recipient
  • Arterial Thrombus in a Heart Transplant Recipient

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Current Issue Highlights

Most humans are infected with the BK polyomavirus, which resides in the urothelium. In immunocompetent individuals, the virus is easily controlled and typically inconsequential. However, in immunosuppressed patients, particularly kidney transplant recipients, immune control of the BK virus is lost, leading to polyomavirus nephropathy (PyVN). Unless recognized early, PyVN can lead to graft loss. In this issue, we present two definitive assessments (Nankivell et al and Drachenberg et al) of the evolution of PyVN in kidney transplant recipients. These longitudinal clinical and histological assessments critically outline the course of BK viral reactivation and will be important for the early recognition and study of this unsolved barrier to long-term graft survival. Also this month, we begin a year-long series examining cancer in transplant recipients (see editorial by Engels), with the first offering in the series, an overview of chemotherapy in transplant patients with malignancy (see Krisl and Doan). Cover image by Lauren Halligan, Duke University Department of Surgery.

Editors' Picks

Chemotherapy and Transplantation: The Role of Immunosuppression in Malignancy and a Review of Antineoplastic Agents in Solid Organ Transplant Recipients
Krisl and Doan

Cancer in Solid Organ Transplant Recipients: There Is Still Much to Learn and Do
Engels

Depletion-Resistant CD4 T Cells Enhance Thymopoiesis During Lymphopenia
Ayasoufi et al

Thymic–Peripheral Crosstalk in Lymphodepletion Therapy
Snyder and Farber

Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney–Bone Marrow Transplantation to Induce Transplantation Tolerance
Sprangers et al

Allo-HLA Cross-Reactivities of Cytomegalovirus-, Influenza-, and Varicella Zoster Virus–Specific Memory T Cells Are Shared by Different Healthy Individuals
van den Heuvel et al

BK Virus Nephropathy: Histological Evolution by Sequential Pathology
Nankivell et al

Histological Evolution of BK Virus–Associated Nephropathy: Importance of Integrating Clinical and Pathological Findings
Drachenberg et al

BK Virus Nephropathy Revisited
Mengel

2017 ATC Video Abstracts


The AJT Report

AJT Report 17.8

2017 American Transplant Congress Focuses on Hot Issues

This month, “The AJT Report” features research presented at this year's American Transplant Congress, held April 29–May 3 in Chicago, and highlights some evolving trends impacting the field of transplantation.


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A Novel Rodent Orthotopic Forelimb Transplantation Model That Allows for Reliable Assessment of Functional Recovery Resulting From Nerve Regeneration
B. Kern, J. D. Budihardjo, S. Mermulla, A. Quan, C. Cadmi, J. Lopez, M. Khusheim, S. Xiang, J. Park, G. J. Furtmüller, K. A. Sarhane, S. Schneeberger, W. P. A. Lee, A. Hoke, S. H. Tuffaha, G. Brandacher


Video S1: Assessment of forelimb function of a naïve animal during natural behavior. The total score of 9 points of the IBB scale has been reached.

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