American Journal of Transplantation
© American Society of Transplantation and the American Society of Transplant Surgeons
Edited By: Allan D. Kirk
Impact Factor: 6.19
ISI Journal Citation Reports © Ranking: 2013: 1/26 (Transplantation); 2/204 (Surgery)
Online ISSN: 1600-6143
Images in Transplantation (CME)
An Unexpected Foreign Body in the Colon of a Heart Transplant Recipient
A 60-Year-Old Man With Necrotic Skin Lesions After Heart Transplantation
Right Homonymous Hemianopsia and Seizures in a Liver Transplant Recipient
Renal Failure in a Kidney Transplant Recipient—BK Virus Nephropathy or Rejection?
Bovine Pericardium Diaphragm Repair of Diaphragmatic Hernia After LVAD Explantation and Heart Transplantation
Emesis Following Laparoscopic Left Donor Nephrectomy
Hemorrhagic Shock One Month Following Uncomplicated Liver Transplantation
Skin Nodule on the Ear of a Kidney–Pancreas Transplant Recipient
Recently Published Issues
Current Issue Highlights
Regulatory T cells (Tregs), specifically CD4+ T cells that express FoxP3 and the high-affinity IL2 receptor CD25, have been increasingly recognized as providing critical balance to protective and alloreactive cytotoxic T cell responses. This has, in turn, spawned growing interest in harnessing Tregs as potential tools for the control of T cell–mediated allograft rejection, with many proposing that ex vivo expanded Tregs could be used therapeutically to induce tolerance. This month, Singh et al show, in a rigorous preclinical primate model, that sirolimus helps foster Treg persistence and function after ex vivo expansion and adoptive transfer. The work is an important step in designing a Treg-based clinical trial and a nice demonstration of cellular transfer techniques in primates. Cover design by Ken North, North Design Group.
Read the Editor's picks of the month:
Superiority of Rapamycin Over Tacrolimus in Preserving Nonhuman Primate Treg Half-Life and Phenotype After Adoptive Transfer
K. Singh, L. Stempora, R. D. Harvey, A. D. Kirk, C. P. Larsen, B. R. Blazar and L. S. Kean
Use of CTLA4Ig for Induction of Mixed Chimerism and Renal Allograft Tolerance in Nonhuman Primates
Y. Yamada, T. Ochiai, S. Boskovic, O. Nadazdin, T. Oura, D. Schoenfeld, K. Cappetta, R.-N. Smith, R. B. Colvin, J. C. Madsen, D. H. Sachs, G. Benichou, A. B. Cosimi and T. Kawai
Azithromycin and the Treatment of Lymphocytic Airway Inflammation After Lung Transplantation
R. Vos, S. E. Verleden, D. Ruttens, E. Vandermeulen, H. Bellon, A. Neyrinck, D. E. Van Raemdonck, J. Yserbyt, L. J. Dupont, E. K. Verbeken, E. Moelants, A. Mortier, P. Proost, D. Schols, B. Cox, G. M. Verleden and B. M. Vanaudenaerde
CLAD: Does the Emperor Have New Clothes?
A. R. Glanville
Randomized, Double-Blind Trial of Anidulafungin Versus Fluconazole for Prophylaxis of Invasive Fungal Infections in High-Risk Liver Transplant Recipients
D.J. Winston, A.P. Limaye, S. Pelletier, N. Safdar, M.I. Morris, K. Meneses, R.W. Busuttil and N. Singh
Antifungal Prophylaxis in Liver Transplantation: A Systematic Review and Network Meta-Analysis
J. D. W. Evans, P. J. Morris and S. R. Knight
Bone Marrow–Derived Hematopoietic Stem and Progenitor Cells Infiltrate Allogeneic and Syngeneic Transplants
Z. Fan, K. Enjoji, J. C. Tigges, V. Toxavidis, V. Tchipashivili, W. Gong, T. B. Strom and M. Koulmanda
Watch the Latest Video in the AJT Video Library:
A Complete Treatment of Adult Living Donor Liver Transplantation: A Review of Surgical Technique and Current Challenges to Expand Indication of Patients
Published online: October 2014
Dual adult-to-adult living donor liver transplantation using two left lobes.
Highly Cited/Highly Read Articles
Read these highly cited articles:
Banff '07 classification of renal allograft pathology: Updates and future directions
Antibody-mediated rejection criteria - an addition to the Banff '97 Classification of Renal Allograft Rejection
Read these highly read articles:
Organ Trafficking and Transplant Tourism: A Commentary on the Global Realities
The AJT Report
News and Information
Get up to speed quickly with the latest in transplantation news from the American Journal of Transplantation newsroom.
Frailty Increases Kidney Transplant Recipients' Risk of Dying Prematurely
Published on 10/30/14
Regardless of age, frailty is a strong risk factor for dying prematurely after a kidney transplant. The finding, which comes from a new study published in the American Journal of Transplantation, suggests that patients should be screened for frailty prior to kidney transplantation, and that those who are identified as frail should be closely monitored after the procedure.
Stay Connected with AJT
AJT is now on Twitter! Follow us @amjtransplant for news, issues, and more.
Virtual issues are collections of articles on a particular subject, published in the American Journal of Transplantation. They are selected by a guest editor to provide a rapid overview of the activity in a particular aspect of transplantation.
The following virtual issues are available:
Guest Editor: Dr. Emily Blumberg
Guest Editors: Drs. Howard M. Gebel and Robert A. Bray
Guest Editor: Dr. Allan D. Kirk