Genes, Brain and Behavior

Cover image for Vol. 15 Issue 2

Edited By: Andrew Holmes

Impact Factor: 3.661

ISI Journal Citation Reports © Ranking: 2014: 7/51 (Behavioral Sciences); 80/252 (Neurosciences)

Online ISSN: 1601-183X

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The new issue of G2B REVIEWS brings together a collection showcasing recent advances in development-related research.  In the spirit of the journal, these FREE REVIEWS span the levels of genes, brain and behavior, and bridge the realms of basic research and clinical work.  Access the entire issue here for free!Read more

Recently Published Articles

  1. Neuropsychological phenotype and psychopathology in seven adult patients with Phelan-McDermid syndrome: Implications for treatment strategy

    Jos I.M. Egger, Renée J. Zwanenburg, Conny M.A. van Ravenswaaij-Arts, Tjitske Kleefstra and Willem M.A. Verhoeven

    Accepted manuscript online: 29 JAN 2016 09:08AM EST | DOI: 10.1111/gbb.12285

  2. You have full text access to this OnlineOpen article
    The D1 family dopamine receptor, DopR, potentiates hind leg grooming behavior in Drosophila

    E. Pitmon, G. Stephens, S. J. Parkhurst, F. W. Wolf, G. Kehne, M. Taylor and T. Lebestky

    Article first published online: 29 JAN 2016 | DOI: 10.1111/gbb.12264

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    Removal of DopR results in decreased hind leg grooming in Drosophila, as substantiated by quantitation of dye remaining on mutant and RNAi animals vs. controls and direct scoring of behavioral events. DopR protein is broadly expressed in the neuropil of the thoracic ganglion and overlaps with TH-positive dopaminergic neurons. Broad neuronal expression of dopamine receptor in mutant animals restored normal grooming behaviors. These data provide evidence for the role of DopR in potentiating hind leg grooming behaviors in the thoracic ganglion of adult Drosophila. This is a remarkable juxtaposition to the considerable role of D1 family dopamine receptors in rodent grooming, and future investigations of evolutionary relationships of circuitry may be warranted.

  3. Associations between neurologic dysfunction and lesions in canine fucosidosis

    J. L. Fletcher and R. M. Taylor

    Article first published online: 22 JAN 2016 | DOI: 10.1111/gbb.12282

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    Neurologic dysfunction score in canine fucosidosis does not increase significantly until 12 months of age.

  4. Scn1a dysfunction alters behavior but not the effect of stress on seizure response

    N. T. Sawyer, A. W. Helvig, C. D. Makinson, M. J. Decker, G. N. Neigh and A. Escayg

    Article first published online: 21 JAN 2016 | DOI: 10.1111/gbb.12281

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    Scn1a voltage-gated sodium channel mutants show deficits in risk assessment.

  5. The divergent impact of COMTVal158Met on executive function in children with and without attention-deficit/hyperactivity disorder (pages 271–279)

    J. Jin, L. Liu, Q. Gao, R. C. K. Chan, H. Li, Y. Chen, Y. Wang and Q. Qian

    Article first published online: 20 JAN 2016 | DOI: 10.1111/gbb.12270

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    We found that association existed between rs4680 genotypes and executive function which was divergent in attention-deficit/hyperactivity disorder children and controls but no ‘when’ effect.