Genes, Brain and Behavior

Cover image for Vol. 13 Issue 4

Edited By: Andrew Holmes

Impact Factor: 3.597

ISI Journal Citation Reports © Ranking: 2012: 10/49 (Behavioral Sciences); 84/252 (Neurosciences)

Online ISSN: 1601-183X

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Read G2B papers selected by the Editor in key thematic areas in our Virtual Issues, including our most recent one 'The molecular machinery of memory'.

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Recently Published Articles

  1. Association between genes, stressful childhood events and processing bias in depression vulnerable individuals

    J. N. Vrijsen, I. van Oostrom, A. Arias-Vásquez, B. Franke, E. S. Becker and A. Speckens

    Article first published online: 16 APR 2014 | DOI: 10.1111/gbb.12129

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    Our findings endorse the association of BDNF and COMT with childhood stress and depression and provide a possible intermediate, i.e. biased processing of positive information.

  2. Genetic effects on information processing speed are moderated by age – converging results from three samples

    M. Ising, K. A. Mather, P. Zimmermann, T. Brückl, N. Höhne, A. Heck, L. A. Schenk, D. Rujescu, N. J. Armstrong, P. S. Sachdev and S. Reppermund

    Article first published online: 8 APR 2014 | DOI: 10.1111/gbb.12132

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    Our GWAS findings demonstrate opposing effects of DSG1 variants on information processing speed depending on the age of the individual.

  3. Glutamic acid decarboxylase 67 haplodeficiency impairs social behavior in mice (pages 439–450)

    K. V. Sandhu, D. Lang, B. Müller, S. Nullmeier, Y. Yanagawa, H. Schwegler and O. Stork

    Article first published online: 3 APR 2014 | DOI: 10.1111/gbb.12131

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    GAD67 haplodeficiency in mice evokes deficits in social behavior, social odor sensitivity and activation of social brain circuits.

  4. Extinction of an instrumental response: A cognitive behavioral assay in Fmr1 knockout mice

    Michael S. Sidorov, Dilja D. Krueger, Madison Taylor, Eugenia Gisin, Emily K. Osterweil and Mark F. Bear

    Accepted manuscript online: 31 MAR 2014 08:10AM EST | DOI: 10.1111/gbb.12137

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    Instrumental extinction is exaggerated in Fmr1 KO mice. a) Schematic shows a test with one acquisition phase, followed by five days of extinction. b) Days to acquisition and c) performance during acquisition are normal in Fmr1 KO mice. d) Extinction of correct responding is significantly exaggerated in Fmr1 KO mice (***p=.001, repeated measures two-way ANOVA), and post-hoc tests show significant exaggeration at days 1-4 (*p < .05). e) Normalization reveals significantly exaggerated extinction in Fmr1KO mice (***p=.001), and post-hoc tests show a significant exaggeration at day 1 (**p<.01). There is no effect of Fmr1 genotype on incorrect responses (f-g) or on the rate of correct responses (h-i).

  5. You have full text access to this OnlineOpen article
    Not all water mazes are created equal: cyclin D2 knockout mice with constitutively suppressed adult hippocampal neurogenesis do show specific spatial learning deficits (pages 357–364)

    A. Garthe, Z. Huang, L. Kaczmarek, R. K. Filipkowski and G. Kempermann

    Article first published online: 29 MAR 2014 | DOI: 10.1111/gbb.12130

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    Cyclin D2 knockout mice with very low levels of adult hippocampal neurogenesis show specific learning deficits in the water maze task.