Genes, Brain and Behavior

Cover image for Vol. 13 Issue 8

Edited By: Andrew Holmes

Impact Factor: 3.505

ISI Journal Citation Reports © Ranking: 2013: 10/49 (Behavioral Sciences); 93/252 (Neurosciences)

Online ISSN: 1601-183X

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Introducing G2B REVIEWS

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This inaugural issue of G2B REVIEWS brings together contributions from nine of the leading laboratories in our field from around the world. Access the entire issue here for free! Read more

Recently Published Articles

  1. NMDA receptor-deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities (pages 850–862)

    M. Milenkovic, C. A. Mielnik and A. J. Ramsey

    Article first published online: 12 NOV 2014 | DOI: 10.1111/gbb.12183

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    NR1KD mice show developmental deficits in social interaction with earlier onset and severity observed in male mutant mice.

  2. Integrated Circuits and Molecular Components for Stress and Feeding: Implications for Eating Disorders

    J. Andrew Hardaway, Nicole A. Crowley, Cynthia M. Bulik and Thomas L. Kash

    Accepted manuscript online: 4 NOV 2014 04:34AM EST | DOI: 10.1111/gbb.12185

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    Eating disorders are complex brain disorders that afflict millions of individuals worldwide. The etiology of these diseases is not fully understood, but a growing body of literature suggests that stress and anxiety may play a critical role in their development. Though a considerable body of research and societal emphasis has been placed on prevention and intervention of both stress-related behaviors and EDs, the combination of the two has only recently come to the forefront of scientific and clinical aims. This review will briefly highlight major EDs and relevant background, discuss rodent models of feeding and EDs and global behavioral work, explore the circuitry of feeding behaviors and how stress manipulations may shift specific aspects of this circuit, and identify some overlapping stress and feeding related molecular systems.

  3. Development and heritability of subcortical brain volumes at ages 9 and 12 (pages 733–742)

    S. C. Swagerman, R. M. Brouwer, E. J. C. de Geus, H. E. Hulshoff Pol and D. I. Boomsma

    Article first published online: 30 OCT 2014 | DOI: 10.1111/gbb.12182

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    In a longitudinal twin study on brain development between 9 and 12 years of age, we show increases in left and right hemisphere volumes of the thalamus, pallidum, hippocampus and amygdala , while volumes of the caudate, nucleus accumbens, and putamen (bilaterally in boys; right-sided only in girls) decreased. Our results show that heritability of all volumes is high from childhood onwards, genetic effects are similar for boys and girls, and we find no evidence for new genetic effects at age 12.