Genes, Brain and Behavior
© John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society
Edited By: Andrew Holmes
Impact Factor: 3.505
ISI Journal Citation Reports © Ranking: 2013: 10/49 (Behavioral Sciences); 93/252 (Neurosciences)
Online ISSN: 1601-183X
Recently Published Articles
- Aggression is Associated with Aerobic Glycolysis in the Honey Bee Brain
Sriram Chandrasekaran, Clare C. Rittschof, Danijel Djukovic, Haiwei Gu, Daniel Raftery, Nathan D. Price and Gene E. Robinson
Accepted manuscript online: 30 JAN 2015 05:03AM EST | DOI: 10.1111/gbb.12201
Relative levels of central metabolism metabolites and genes in the aggressive brain. Metabolites are listed in circles and genes are in rectangles. Metabolites in white were not measured. Dark green and dark red colors represent changes in metabolites and mRNA that were statistically significant (a decrease or increase, respectively) according to gene expression and metabolite data from honeybees treated with alarm pheromone versus control. Light green and light red colors represent a non-significant decrease or increase, respectively. Protein complexes in the oxidative phosphorylation pathway, which are composed of variable numbers of protein subunits, are drawn as cartoons that represent the physical shapes of the complexes. Complexes are colored green to represent the general down regulation of the transcripts that encode protein constituents. Circles with black and dotted borders were compounds that were indistinguishable from one another in the metabolomics analysis. Abbreviations: Glucose – GLC, Pyruvate – PYR, Oxaloacetate – OAA, Citrate – CIT, Alpha-ketoglutarate - AKG, succinate – SUC, Fumarate – FUM, Malate – MAL, Succinyl-COA - SCA, Glutamate – GLU, Glutamine – GLN, Lactate – LAC, Alanine – ALA, Glucose 6 phosphate - G6P, Fructose 6 phosphate - F6P, Fructose 1,6 bis phosphate – FBP, Glyceraldehyde 3 Phosphate – GADP, Dihydroxyacetone Phosphate – DHAP, 1,3 bisphosphoglycerate - 1,3BPG, 3 phosphoglycerate - 3PG, 2 phosphoglycerate - 2PG, Phosphoenolpyruvate – PEP.
- You have free access to this contentIntegrated circuits and molecular components for stress and feeding: implications for eating disorders (pages 85–97)
J. A. Hardaway, N. A. Crowley, C. M. Bulik and T. L. Kash
Article first published online: 28 JAN 2015 | DOI: 10.1111/gbb.12185
Eating disorders are complex brain disorders that afflict millions of individuals worldwide. The etiology of these diseases is not fully understood, but a growing body of literature suggests that stress and anxiety may play a critical role in their development. Though a considerable body of research and societal emphasis has been placed on prevention and intervention of both stress-related behaviors and eating disorders (EDs), the combination of the two has only recently come to the forefront of scientific and clinical aims. This review will briefly highlight major EDs and relevant background, discuss rodent models of feeding and EDs and global behavioral work, explore the circuitry of feeding behaviors and how stress manipulations may shift specific aspects of this circuit, and identify some overlapping stress and feeding-related molecular systems.
- You have free access to this contentThe GAD65 knock out mouse – a model for GABAergic processes in fear- and stress-induced psychopathology (pages 37–45)
Iris Müller, Gürsel Çalışkan and Oliver Stork
Article first published online: 28 JAN 2015 | DOI: 10.1111/gbb.12188
GAD65 is involved in anxiety. Here we review characteristics of the GAD65 knock out mouse and highlight its relevance for psychiatric research.
- You have free access to this contentEpigenetics and memory: causes, consequences and treatments for post-traumatic stress disorder and addiction (pages 73–84)
C. L. Pizzimenti and K. M. Lattal
Article first published online: 28 JAN 2015 | DOI: 10.1111/gbb.12187
Overlapping behavioral, neurobiological and epigenetic mechanisms control the extinction of learned fear and drug-seeking responses.
- You have free access to this contentBehavioral flexibility in rats and mice: contributions of distinct frontocortical regions (pages 4–21)
D. A. Hamilton and J. L. Brigman
Article first published online: 28 JAN 2015 | DOI: 10.1111/gbb.12191
Reversal learning, inhibitory learning and extradimensional set shifting have been extensively used to investigate the frontocortical bases of behavioral flexibility. This article reviews the current literature linking behavioral flexibility in these tasks to distinct subregions of frontal cortex in rats and mice.