Genes, Brain and Behavior
© John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society
Edited By: Andrew Holmes
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ISI Journal Citation Reports © Ranking: 2012: 10/49 (Behavioral Sciences); 84/252 (Neurosciences)
Online ISSN: 1601-183X
Recently Published Articles
- SIRPB1 copy-number polymorphism as candidate quantitative trait locus for impulsive-disinhibited personality
M. Laplana, J. L. Royo, L. F. García, A. Aluja, J. L. Gomez-Skarmeta and J. Fibla
Article first published online: 23 JUL 2014 | DOI: 10.1111/gbb.12154
A CNV mapping to gene SIRPB1 was significantly associated with impulsive-disinhibited personality scores in a dose-dependent manner.
- Food deprivation and nicotine correct akinesia and freezing in Na+-leak current channel (NALCN)-deficient strains of Caenorhabditis elegans
K. Bonnett, R. Zweig, E. J. Aamodt and D. S. Dwyer
Article first published online: 23 JUL 2014 | DOI: 10.1111/gbb.12153
Nicotine and food deprivation correct abnormal movement (akinesia and freezing) in NALCN-deficient C. elegans.
- CHRNA5 variants moderate the effect of nicotine deprivation on a neural index of cognitive control
D. E. Evans, D. A. MacQueen, K. G. Jentink, J. Y. Park, H.-Y. Lin and D. J. Drobes
Article first published online: 23 JUL 2014 | DOI: 10.1111/gbb.12151
Nicotine deprivation reduces P3a amplitude among minor allele carriers at rs588765, rs17408276 and rs3829787.
- Methyl CpG Binding Domain Ultra-Sequencing: a novel method for identifying inter-individual and cell-type-specific variation in DNA methylation
X. Li, D. Baker-Andresen, Q. Zhao, V. Marshall and T. W. Bredy
Article first published online: 23 JUL 2014 | DOI: 10.1111/gbb.12150
Methyl CpG binding domain Ultra-Sequencing (MBD Ultra-Seq) is a robust method for detecting DNA methylation in neurons derived from discrete brain regions of individual animals. We demonstrate the value of this method by characterizing differences in 5-methylcytosine (5mC) in neurons and non-neurons of the ventromedial prefrontal cortex of individual adult C57BL/6 mice, using as little as 50 ng of genomic DNA per sample. This protocol will facilitate the detection of experience-dependent changes in DNA methylation in a variety of behavioural paradigms and help identify aberrant experience-induced DNA methylation that may underlie risk and resiliency to neuropsychiatric disease.
- Do individually ventilated cage systems generate a problem for genetic mouse model research?
W. Logge, J. Kingham and T. Karl
Article first published online: 23 JUL 2014 | DOI: 10.1111/gbb.12149
Nrg1 mutant mice of IVC housing do not show impairments in prepulse inhibition, which is characteristic for FILTER-housed mutants.