Genes, Brain and Behavior

Cover image for Vol. 14 Issue 4

Edited By: Andrew Holmes

Impact Factor: 3.505

ISI Journal Citation Reports © Ranking: 2013: 10/49 (Behavioral Sciences); 93/252 (Neurosciences)

Online ISSN: 1601-183X

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The new issue of G2B REVIEWS brings together a collection showcasing recent advances in stress-related research.  In the spirit of the journal, these FREE REVIEWS span the levels of genes, brain and behavior, and bridge the realms of basic research and clinical work.  Access the entire issue here for free!Read more

Recently Published Articles

  1. A Genome-Wide Sib-Pair Scan for Quantitative Language Traits Reveals Linkage to Chromosomes 10 and 13

    Patrick D. Evans, Kathryn L. Mueller, Eric R. Gamazon, Nancy J. Cox and J. Bruce Tomblin

    Accepted manuscript online: 21 MAY 2015 01:28AM EST | DOI: 10.1111/gbb.12223

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    Here we report the first linkage study to screen the continuum of language ability, from normal to disordered, as found in the general population. 383 children from 147 sib-ships were genotyped using three composite language-related phenotypes and a measure of phonological memory (PM). Two regions (10q23.33; 13q33.3) yielded genome-wide significant peaks for linkage with PM. A peak suggestive of linkage was also found at 17q12 for the overall language composite. This study presents two novel genetic loci for the study of language development and disorders, but fails to replicate findings by previous groups.

  2. Physiological and behavioral effects of amphetamine in BACE1−/− mice

    R. Madelaine Paredes, E. Piccart, E. Navaira, D. Cruz, M. A. Javors, W. Koek, M. J. Beckstead and C. Walss-Bass

    Article first published online: 21 MAY 2015 | DOI: 10.1111/gbb.12222

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    Our study provides evidence that decreased availability of BACE1 can produce persistent adaptations in the dopaminergic system.

  3. Differences in inhibitory avoidance, cortisol and brain gene expression in TL and AB zebrafish

    M. Gorissen, R. Manuel, T. N. M. Pelgrim, W. Mes, M. J. S. de Wolf, J. Zethof, G. Flik and R. van den Bos

    Article first published online: 21 MAY 2015 | DOI: 10.1111/gbb.12220

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    Zebrafish strain-based differences in inhibitory avoidance behaviour.

  4. LPHN3 and Attention-Deficit/Hyperactivity Disorder: a susceptibility and pharmacogenetics study

    Estela M Bruxel, Angélica Salatino-Oliveira, Glaucia C Akutagava-Martins, Luciana Tovo-Rodrigues, Julia P Genro, Cristian P Zeni, Guilherme V Polanczyk, Rodrigo Chazan, Marcelo Schmitz, Mauricio Arcos-Burgos, Luis A Rohde and Mara H Hutz

    Accepted manuscript online: 19 MAY 2015 04:31AM EST | DOI: 10.1111/gbb.12224

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    This study reports that LPHN3 confers ADHD susceptibility, and moderates MPH treatment response in children and adolescents with ADHD.

  5. Distinct ethanol drinking microstructures in two replicate lines of mice selected for drinking to intoxication

    Amanda M. Barkley-Levenson and John C. Crabbe

    Accepted manuscript online: 15 MAY 2015 08:57AM EST | DOI: 10.1111/gbb.12225

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    The two High Drinking in the Dark replicate mouse lines have distinct drinking microstructures that both lead to binge-like ethanol intake.