Genes, Brain and Behavior
© John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society
Edited By: Andrew Holmes
Impact Factor: 3.597
ISI Journal Citation Reports © Ranking: 2012: 10/49 (Behavioral Sciences); 84/252 (Neurosciences)
Online ISSN: 1601-183X
Recently Published Articles
- Association between genes, stressful childhood events and processing bias in depression vulnerable individuals
J. N. Vrijsen, I. van Oostrom, A. Arias-Vásquez, B. Franke, E. S. Becker and A. Speckens
Article first published online: 16 APR 2014 | DOI: 10.1111/gbb.12129
Our findings endorse the association of BDNF and COMT with childhood stress and depression and provide a possible intermediate, i.e. biased processing of positive information.
- Genetic effects on information processing speed are moderated by age – converging results from three samples
M. Ising, K. A. Mather, P. Zimmermann, T. Brückl, N. Höhne, A. Heck, L. A. Schenk, D. Rujescu, N. J. Armstrong, P. S. Sachdev and S. Reppermund
Article first published online: 8 APR 2014 | DOI: 10.1111/gbb.12132
Our GWAS findings demonstrate opposing effects of DSG1 variants on information processing speed depending on the age of the individual.
- Glutamic acid decarboxylase 67 haplodeficiency impairs social behavior in mice (pages 439–450)
K. V. Sandhu, D. Lang, B. Müller, S. Nullmeier, Y. Yanagawa, H. Schwegler and O. Stork
Article first published online: 3 APR 2014 | DOI: 10.1111/gbb.12131
GAD67 haplodeficiency in mice evokes deficits in social behavior, social odor sensitivity and activation of social brain circuits.
- Extinction of an instrumental response: A cognitive behavioral assay in Fmr1 knockout mice
Michael S. Sidorov, Dilja D. Krueger, Madison Taylor, Eugenia Gisin, Emily K. Osterweil and Mark F. Bear
Accepted manuscript online: 31 MAR 2014 08:10AM EST | DOI: 10.1111/gbb.12137
Instrumental extinction is exaggerated in Fmr1 KO mice. a) Schematic shows a test with one acquisition phase, followed by five days of extinction. b) Days to acquisition and c) performance during acquisition are normal in Fmr1 KO mice. d) Extinction of correct responding is significantly exaggerated in Fmr1 KO mice (***p=.001, repeated measures two-way ANOVA), and post-hoc tests show significant exaggeration at days 1-4 (*p < .05). e) Normalization reveals significantly exaggerated extinction in Fmr1KO mice (***p=.001), and post-hoc tests show a significant exaggeration at day 1 (**p<.01). There is no effect of Fmr1 genotype on incorrect responses (f-g) or on the rate of correct responses (h-i).
- You have full text access to this OnlineOpen articleNot all water mazes are created equal: cyclin D2 knockout mice with constitutively suppressed adult hippocampal neurogenesis do show specific spatial learning deficits (pages 357–364)
A. Garthe, Z. Huang, L. Kaczmarek, R. K. Filipkowski and G. Kempermann
Article first published online: 29 MAR 2014 | DOI: 10.1111/gbb.12130
Cyclin D2 knockout mice with very low levels of adult hippocampal neurogenesis show specific learning deficits in the water maze task.