Genes, Brain and Behavior

Cover image for Vol. 13 Issue 7

Edited By: Andrew Holmes

Impact Factor: 3.505

ISI Journal Citation Reports © Ranking: 2013: 10/49 (Behavioral Sciences); 93/251 (Neurosciences)

Online ISSN: 1601-183X

Recently Published Issues

See all

Virtual Issues

Read more

Read G2B papers selected by the Editor in key thematic areas in our Virtual Issues, including our most recent one 'The molecular machinery of memory'.

Read more

Recently Published Articles

  1. Genetics of gene expression characterizes response to selective breeding for alcohol preference

    P. L. Hoffman, L. M. Saba, S. Flink, N. J. Grahame, K. Kechris and B. Tabakoff

    Article first published online: 29 SEP 2014 | DOI: 10.1111/gbb.12175

    Thumbnail image of graphical abstract

    Genetics of gene expression can be used to identify genomic regions fixed during artificial selection. Priority genes with expression difference from selective breeding for alcohol preference.

  2. Expression of Glutamatergic Genes in Healthy Humans across 16 Brain Regions; Altered Expression in the Hippocampus after Chronic Exposure to Alcohol or Cocaine

    Mary-Anne Enoch, Alexandra A. Rosser, Zhifeng Zhou, Deborah C. Mash, Qiaoping Yuan and David Goldman

    Accepted manuscript online: 29 SEP 2014 03:44AM EST | DOI: 10.1111/gbb.12179

    Thumbnail image of graphical abstract

    Chronic alcohol use up-regulates glutamatergic gene expression in human hippocampus; strongest effect is on GRIN2B encoding GluN2B.

  3. Increased behavioral responses to ethanol in Lmo3 knockout mice

    A. Savarese, M. E. Zou, V. Kharazia, R. Maiya and A. W. Lasek

    Article first published online: 24 SEP 2014 | DOI: 10.1111/gbb.12176

    Thumbnail image of graphical abstract

    Increased binge-like ethanol consumption in Lmo3 null mice.

  4. A Genetic Interaction Network Model of a Complex Neurological Disease

    Anna L. Tyler, Tracy C. McGarr, Barbara J. Beyer, Wayne N. Frankel and Gregory W. Carter

    Accepted manuscript online: 23 SEP 2014 02:31AM EST | DOI: 10.1111/gbb.12178

    Thumbnail image of graphical abstract

    In this study, we derive a network of quantitative trait loci (QTL) that combine to cause absence epilepsy in a mouse intercross population using a recently developed computational approach, the Combined Analysis of Pleiotropy and Epistasis (CAPE). We demonstrate a substantial improvement in the power to detect QTL and generate a genetic model of how multiple novel loci interact to influence pathological neurophenotypes.

  5. Central dopamine action modulates neuropeptide-controlled appetite via the hypothalamic PI3K/NF-κB-dependent mechanism

    Y.-S. Hsieh, P.-N. Chen, C.-H. Yu and D.-Y. Kuo

    Article first published online: 19 SEP 2014 | DOI: 10.1111/gbb.12174

    Thumbnail image of graphical abstract

    Dopamine–PI3K–NF-κB signaling in the hypothalamus plays functional roles in the modulation of NPY and POMC neurotransmissions and in the control of AMPH-evoked appetite suppression.