Genes, Brain and Behavior
© John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society
Edited By: Andrew Holmes
Impact Factor: 3.505
ISI Journal Citation Reports © Ranking: 2013: 10/49 (Behavioral Sciences); 93/251 (Neurosciences)
Online ISSN: 1601-183X
Recently Published Articles
- Genetics of gene expression characterizes response to selective breeding for alcohol preference
P. L. Hoffman, L. M. Saba, S. Flink, N. J. Grahame, K. Kechris and B. Tabakoff
Article first published online: 29 SEP 2014 | DOI: 10.1111/gbb.12175
Genetics of gene expression can be used to identify genomic regions fixed during artificial selection. Priority genes with expression difference from selective breeding for alcohol preference.
- Expression of Glutamatergic Genes in Healthy Humans across 16 Brain Regions; Altered Expression in the Hippocampus after Chronic Exposure to Alcohol or Cocaine
Mary-Anne Enoch, Alexandra A. Rosser, Zhifeng Zhou, Deborah C. Mash, Qiaoping Yuan and David Goldman
Accepted manuscript online: 29 SEP 2014 03:44AM EST | DOI: 10.1111/gbb.12179
Chronic alcohol use up-regulates glutamatergic gene expression in human hippocampus; strongest effect is on GRIN2B encoding GluN2B.
- Increased behavioral responses to ethanol in Lmo3 knockout mice
A. Savarese, M. E. Zou, V. Kharazia, R. Maiya and A. W. Lasek
Article first published online: 24 SEP 2014 | DOI: 10.1111/gbb.12176
- A Genetic Interaction Network Model of a Complex Neurological Disease
Anna L. Tyler, Tracy C. McGarr, Barbara J. Beyer, Wayne N. Frankel and Gregory W. Carter
Accepted manuscript online: 23 SEP 2014 02:31AM EST | DOI: 10.1111/gbb.12178
In this study, we derive a network of quantitative trait loci (QTL) that combine to cause absence epilepsy in a mouse intercross population using a recently developed computational approach, the Combined Analysis of Pleiotropy and Epistasis (CAPE). We demonstrate a substantial improvement in the power to detect QTL and generate a genetic model of how multiple novel loci interact to influence pathological neurophenotypes.
- Central dopamine action modulates neuropeptide-controlled appetite via the hypothalamic PI3K/NF-κB-dependent mechanism
Y.-S. Hsieh, P.-N. Chen, C.-H. Yu and D.-Y. Kuo
Article first published online: 19 SEP 2014 | DOI: 10.1111/gbb.12174
Dopamine–PI3K–NF-κB signaling in the hypothalamus plays functional roles in the modulation of NPY and POMC neurotransmissions and in the control of AMPH-evoked appetite suppression.