Genes, Brain and Behavior

Cover image for Vol. 15 Issue 8

Edited By: Andrew Holmes

Impact Factor: 3.275

ISI Journal Citation Reports © Ranking: 2015: 8/51 (Behavioral Sciences); 93/256 (Neurosciences)

Online ISSN: 1601-183X

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The new 2016 issue of G2B REVIEWS brings the question of development into focus with a collection of reviews by researchers who are leading efforts to understand how brain and behavior are shaped during the formative years of early life, and decipher the mechanisms by which genes and early environmental experience impact risk for an array of mental illnesses. This collection of 12 reviews provides a very timely perspective on the current state of developmental research across a range of fields and illuminates some of the exciting paths this work is bound for in the coming years. Access the entire issue for free:click here

Recently Published Articles

  1. You have free access to this content
    Alcohol-Dependent Molecular Adaptations of the NMDA Receptor System

    Nadege Morisot and Dorit Ron

    Accepted manuscript online: 1 DEC 2016 10:48AM EST | DOI: 10.1111/gbb.12363

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    This review focuses on findings in humans and rodents that support the implication of NMDAR signaling in the alcohol use disorders

  2. The impact of CACNA1C gene, and its epistasis with ZNF804A, on white matter microstructure in health, schizophrenia and bipolar disorder1

    E. Mallas, F. Carletti, C. A. Chaddock, S. Shergill, J. Woolley, M. M. Picchioni, C. McDonald, T. Toulopoulou, E. Kravariti, S. Kalidindi, E. Bramon, R. Murray, G. J. Barker and D. P. Prata

    Version of Record online: 29 NOV 2016 | DOI: 10.1111/gbb.12355

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    Psychosis risk variant for calcium-channel CACNA1C rs1006737 polymorphism is asociated with decreased microstructural white matter intergity in portions of the left middle occipital and parahippocampal gyri, right cerebelleum, left optic radiation and left inferior and superior temporal gyri, in schizophrenia patients.

  3. You have free access to this content
    Regulation of behaviour by the nuclear receptor TLX

    J. D. O'Leary, O. F. O'Leary, J. F. Cryan and Y. M. Nolan

    Version of Record online: 29 NOV 2016 | DOI: 10.1111/gbb.12357

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    The nuclear receptor Tlx regulates cognitive, motor, anxiety and aggressive behaviours.

  4. Standardised experiments in mutant mice reveal behavioural similarity on 129S5 and C57BL/6J backgrounds

    Louie N. van de Lagemaat, Lianne E. Stanford, Charles Pettit, Douglas J. Strathdee, Karen E. Strathdee, Kathryn A. Elsegood, David G. Fricker, Mike D. R. Croning, Noboru H. Komiyama and Seth G. N. Grant

    Accepted manuscript online: 25 NOV 2016 05:40AM EST | DOI: 10.1111/gbb.12364

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    Comparison of effect sizes shows postsynaptic mutant behavioral phenotypes are similar between 129S5 and C57BL/6J mice.

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    Reprogramming of mPFC transcriptome and function in alcohol dependence

    M. Heilig, E. Barbier, A. L. Johnstone, J. Tapocik, M. W. Meinhardt, S. Pfarr, C. Wahlestedt and W. H. Sommer

    Version of Record online: 24 NOV 2016 | DOI: 10.1111/gbb.12344

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    Post-dependent reprogramming of transcriptome responses in the mPFC affects local cue-responsive neuronal networks.