Genes, Brain and Behavior

Cover image for Vol. 15 Issue 6

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: Andrew Holmes

Impact Factor: 3.275

ISI Journal Citation Reports © Ranking: 2015: 8/51 (Behavioral Sciences); 93/256 (Neurosciences)

Online ISSN: 1601-183X

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  1. Original Articles

    1. Pseudohypoparathyroidism Type I-b with neurological involvement is associated with a homozygous PTH1R mutation

      Rita Guerreiro, José Brás, Sónia Batista, Paula Pires, Helena Ribeiro, Rosário Almeida, Catarina Oliveira, John Hardy and Isabel Santana

      Accepted manuscript online: 14 JUL 2016 08:45AM EST | DOI: 10.1111/gbb.12308

      Thumbnail image of graphical abstract

      Identification of the homozygous p.Arg186His mutation in PTH1R as associated with Pseudohypoparathyroidism Type I-b with neurological involvement in a Portuguese family

    2. Interplay between stress response genes associated with attention deficit-hyperactivity disorder and brain volume

      Dennis van der Meer, Pieter J. Hoekstra, Janita Bralten, Marjolein van Donkelaar, Dirk J. Heslenfeld, Jaap Oosterlaan, Stephen V. Faraone, Barbara Franke, Jan K. Buitelaar and Catharina A. Hartman

      Accepted manuscript online: 8 JUL 2016 08:41AM EST | DOI: 10.1111/gbb.12307

      Thumbnail image of graphical abstract

      We found a significant gene-environment interaction between variation in the glucocorticoid receptor gene NR3C1 and long-term stress exposure on ADHD symptom count. This effect was further moderated by the serotonin transporter polymorphism 5-HTTLPR. These interactions were reflected in gray matter volume of posterior brain regions involved in processing of social cues. The pattern of findings fit very well with the literature on stress exposure, together with the central role of the two genes in regulation of the hypothalamic pituitary adrenal (HPA) axis, the primary stress response pathway, and its association with ADHD.

    3. Circadian genes and lithium response in bipolar disorders:Associations with PPARGC1A (PGC-1α) and RORA

      Pierre Alexis Geoffroy, Bruno Etain, Mohamed Lajnef, El-Hadi Zerdazi, Clara Brichant-Petitjean, Urs Heilbronner, Liping Hou, Franziska Degenhardt, Marcella Rietschel, Francis J. McMahon, Thomas G. Schulze, Stéphane Jamain, Cynthia Marie-Claire and Frank Bellivier

      Accepted manuscript online: 21 JUN 2016 04:20AM EST | DOI: 10.1111/gbb.12306

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      Genetic associations between lithium response and two close biological circadian partners : PPARGC1A (PGC-1?) and RORA.

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