FEBS Journal

Cover image for Vol. 282 Issue 4

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Seamus Martin

Impact Factor: 3.986

ISI Journal Citation Reports © Ranking: 2013: 85/291 (Biochemistry & Molecular Biology)

Online ISSN: 1742-4658

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  1. 1 - 67
  1. Original Articles

    1. Cryptococcus gattii urease as a virulence factor and the relevance of enzymatic activity in cryptococcosis pathogenesis

      Vanessa Feder, Lívia Kmetzsch, Charley Christian Staats, Natalia Vidal-Figueiredo, Rodrigo Ligabue-Braun, Célia Regina Carlini and Marilene Henning Vainstein

      Article first published online: 2 MAR 2015 | DOI: 10.1111/febs.13229

    2. Synaptotagmin I, a molecular target for the steroid hormone signaling controlling maturation of sexual behavior in an insect

      Françoise Bozzolan, Line Duportets, Denis Limousin, Marie-Anne Wycke, Elodie Demondion, Adrien François, Antoine Abrieux and Stéphane Debernard

      Article first published online: 2 MAR 2015 | DOI: 10.1111/febs.13231

    3. Evidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosis

      Sandeep K. Ravala, Suruchi Singh, Ghanshyam S. Yadav, Sanjay Kumar, Subramanian Karthikeyan and Pradip K. Chakraborti

      Article first published online: 2 MAR 2015 | DOI: 10.1111/febs.13230

  2. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      The ribB FMN riboswitch from Escherichia coli operates at the transcriptional and translational level and regulates riboflavin biosynthesis

      Danielle Pedrolli, Simone Langer, Birgit Hobl, Julia Schwarz, Masayuki Hashimoto and Matthias Mack

      Article first published online: 27 FEB 2015 | DOI: 10.1111/febs.13226

  3. Original Articles

    1. ClpL is a chaperone without auxiliary factors

      Sang-Sang Park, Hyog-Young Kwon, Thao Dang-Hien Tran, Moo-Hyun Choi, Seung-Ha Jung, Sangho Lee, David E. Briles and Dong-Kwon Rhee

      Article first published online: 27 FEB 2015 | DOI: 10.1111/febs.13228

  4. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction

      Domen Zafred, Barbara Steiner, Andrea R. Teufelberger, Altijana Hromic, P. Andrew Karplus, Christopher J. Schofield, Silvia Wallner and Peter Macheroux

      Article first published online: 24 FEB 2015 | DOI: 10.1111/febs.13212

  5. Original Articles

    1. From crystal structure to in silico epitope discovery in the Burkholderia pseudomallei flagellar hook-associated protein FlgK

      Louise J. Gourlay, Rachael J. Thomas, Claudio Peri, Oscar Conchillo-Solé, Mario Ferrer-Navarro, Arnone Nithichanon, Jordi Vila, Xavier Daura, Ganjana Lertmemongkolchai, Richard Titball, Giorgio Colombo and Martino Bolognesi

      Article first published online: 23 FEB 2015 | DOI: 10.1111/febs.13223

    2. Biocatalytic carboxylation of phenol derivatives: kinetics and thermodynamics of the biological Kolbe–Schmitt synthesis

      Lorenzo Pesci, Silvia M. Glueck, Pavel Gurikov, Irina Smirnova, Kurt Faber and Andreas Liese

      Article first published online: 23 FEB 2015 | DOI: 10.1111/febs.13225

  6. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      Aromatic stacking interactions govern catalysis in aryl-alcohol oxidase

      Patricia Ferreira, Aitor Hernández-Ortega, Fátima Lucas, Juan Carro, Beatriz Herguedas, Kenneth W. Borrelli, Victor Guallar, Angel T. Martínez and Milagros Medina

      Article first published online: 23 FEB 2015 | DOI: 10.1111/febs.13221

  7. Review Articles

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      Lignin-degrading enzymes

      Loredano Pollegioni, Fabio Tonin and Elena Rosini

      Article first published online: 20 FEB 2015 | DOI: 10.1111/febs.13224

  8. Original Articles

    1. SATB2 suppresses the progression of colorectal cancer cells via inactivation of MEK5/ERK5 signaling

      Mohammed A. Mansour, Toshinori Hyodo, Satoko Ito, Kenji Kurita, Toshio Kokuryo, Keisuke Uehara, Masato Nagino, Masahide Takahashi, Michinari Hamaguchi and Takeshi Senga

      Article first published online: 18 FEB 2015 | DOI: 10.1111/febs.13227

    2. Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris

      Valery Kh. Akparov, Vladimir I. Timofeev, Ilyas G. Khaliullin, Vytas Švedas, Galina G. Chestukhina and Inna P. Kuranova

      Article first published online: 18 FEB 2015 | DOI: 10.1111/febs.13210

    3. Bile salt recognition by human liver fatty acid binding protein

      Filippo Favretto, Carlo Santambrogio, Mariapina D'Onofrio, Henriette Molinari, Rita Grandori and Michael Assfalg

      Article first published online: 18 FEB 2015 | DOI: 10.1111/febs.13218

    4. Dual inhibition of Cdc2 protein kinase activation during apoptosis in Xenopus egg extracts

      Yuichi Tsuchiya, Shin Murai and Shigeru Yamashita

      Article first published online: 18 FEB 2015 | DOI: 10.1111/febs.13217

    5. Mycobacterium tuberculosis RecA is indispensable for inhibition of the mitogen-activated protein kinase-dependent bactericidal activity of THP-1-derived macrophages in vitro

      Izabela Szulc-Kielbik, Marta Brzezinska, Michal Kielbik, Anna Brzostek, Jaroslaw Dziadek, Katarzyna Kania, Zofia Sulowska, Agnieszka Krupa and Magdalena Klink

      Article first published online: 13 FEB 2015 | DOI: 10.1111/febs.13219

    6. How pyridoxal 5′-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state

      Giorgio Giardina, Paolo Brunotti, Alessio Fiascarelli, Alessandra Cicalini, Mauricio G. S. Costa, Ashley M. Buckle, Martino L. di Salvo, Alessandra Giorgi, Marina Marani, Alessio Paone, Serena Rinaldo, Alessandro Paiardini, Roberto Contestabile and Francesca Cutruzzolà

      Article first published online: 13 FEB 2015 | DOI: 10.1111/febs.13211

    7. Overexpression of microRNA-30a inhibits hepatitis B virus X protein-induced autophagosome formation in hepatic cells

      Satendra Kumar, Parul Gupta, Sweta Khanal, Aashirwad Shahi, Pushpendra Kumar, Shiv K. Sarin and Senthil K. Venugopal

      Article first published online: 13 FEB 2015 | DOI: 10.1111/febs.13209

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      Glutamate 338 is an electrostatic facilitator of C–Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase

      Binuraj R. K. Menon, Navya Menon, Karl Fisher, Stephen E. J. Rigby, David Leys and Nigel S. Scrutton

      Article first published online: 12 FEB 2015 | DOI: 10.1111/febs.13215

  9. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      Crystal structures of apo-DszC and FMN-bound DszC from Rhodococcus erythropolis D-1

      Li-Jun Guan, Woo Cheol Lee, Shipeng Wang, Takashi Ohshiro, Yoshikazu Izumi, Jun Ohtsuka and Masaru Tanokura

      Article first published online: 11 FEB 2015 | DOI: 10.1111/febs.13216

  10. Original Articles

    1. Analysis of insulin receptor substrate signaling dynamics on microstructured surfaces

      Peter Lanzerstorfer, Yosuke Yoneyama, Fumihiko Hakuno, Ulrike Müller, Otmar Höglinger, Shin-Ichiro Takahashi and Julian Weghuber

      Article first published online: 11 FEB 2015 | DOI: 10.1111/febs.13213

    2. Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling

      Zongyuan Yang, Yi Liu, Jing Liao, Cheng Gong, Chaoyang Sun, Xiaoshui Zhou, Xiao Wei, Taoran Zhang, Qinglei Gao, Ding Ma and Gang Chen

      Article first published online: 11 FEB 2015 | DOI: 10.1111/febs.13206

    3. Pliable natural biocide: Jaburetox is an intrinsically disordered insecticidal and fungicidal polypeptide derived from jack bean urease

      Fernanda C. Lopes, Olena Dobrovolska, Rafael Real-Guerra, Valquiria Broll, Barbara Zambelli, Francesco Musiani, Vladimir N. Uversky, Célia R. Carlini and Stefano Ciurli

      Article first published online: 11 FEB 2015 | DOI: 10.1111/febs.13201

    4. You have full text access to this OnlineOpen article
      ‘Dopamine-first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile

      Benjamin R. Lichman, Markus C. Gershater, Eleanor D. Lamming, Thomas Pesnot, Altin Sula, Nicholas H. Keep, Helen C. Hailes and John M. Ward

      Article first published online: 9 FEB 2015 | DOI: 10.1111/febs.13208

    5. Structural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases

      Hanna-Kirsti S. Leiros, Kine Susann Waade Edvardsen, Gro Elin Kjæreng Bjerga and Ørjan Samuelsen

      Article first published online: 6 FEB 2015 | DOI: 10.1111/febs.13200

    6. Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism

      Amlan Roychowdhury, Anirban Kundu, Madhuparna Bose, Akanksha Gujar, Somnath Mukherjee and Amit Kumar Das

      Article first published online: 6 FEB 2015 | DOI: 10.1111/febs.13205

    7. Mathematical modeling improves EC50 estimations from classical dose–response curves

      Elin Nyman, Isa Lindgren, William Lövfors, Karin Lundengård, Ida Cervin, Theresia Arbring Sjöström, Jordi Altimiras and Gunnar Cedersund

      Article first published online: 6 FEB 2015 | DOI: 10.1111/febs.13194

    8. A small lytic polysaccharide monooxygenase from Streptomyces griseus targeting α- and β-chitin

      Yuko S. Nakagawa, Madoka Kudo, Jennifer S. M. Loose, Takahiro Ishikawa, Kazuhide Totani, Vincent G. H. Eijsink and Gustav Vaaje-Kolstad

      Article first published online: 4 FEB 2015 | DOI: 10.1111/febs.13203

  11. Review Articles

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      The conformational plasticity of eukaryotic RNA-dependent ATPases

      Sevim Ozgur, Gretel Buchwald, Sebastian Falk, Sutapa Chakrabarti, Jesuraj Rajan Prabu and Elena Conti

      Article first published online: 4 FEB 2015 | DOI: 10.1111/febs.13198

  12. Original Articles

    1. Active ERK2 is sufficient to mediate growth arrest and differentiation signaling

      Pui–Kei Wu, Seung–Keun Hong, Seung–Hee Yoon and Jong–In Park

      Article first published online: 3 FEB 2015 | DOI: 10.1111/febs.13197

    2. Intrinsic binding of 4-substituted-2,3,5,6-tetrafluorobenezenesulfonamides to native and recombinant human carbonic anhydrase VI

      Justina Kazokaitė, Goda Milinavičiūtė, Joana Smirnovienė, Jurgita Matulienė and Daumantas Matulis

      Article first published online: 30 JAN 2015 | DOI: 10.1111/febs.13196

  13. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      You have full text access to this OnlineOpen article
  14. Original Articles

    1. Listeria monocytogenes has a functional chitinolytic system and an active lytic polysaccharide monooxygenase

      Dafni K. Paspaliari, Jennifer S. M. Loose, Marianne H. Larsen and Gustav Vaaje-Kolstad

      Article first published online: 29 JAN 2015 | DOI: 10.1111/febs.13191

  15. Review Articles

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  16. Original Articles

    1. An A1–A1 mutant with improved binding and inhibition of β2GPI/antibody complexes in antiphospholipid syndrome

      Alexey Kolyada, Ioannis Karageorgos, Pardeep Mahlawat and Natalia Beglova

      Article first published online: 27 JAN 2015 | DOI: 10.1111/febs.13185

    2. Human X-DING-CD4 mediates resistance to HIV-1 infection through novel paracrine-like signaling

      Rakhee Sachdeva, Yuchang Li, Rasheda Y. Shilpi and Malgorzata Simm

      Article first published online: 27 JAN 2015 | DOI: 10.1111/febs.13192

    3. Poly(A)+ mRNA-binding protein Tudor-SN regulates stress granules aggregation dynamics

      Xingjie Gao, Xue Fu, Juan Song, Yi Zhang, Xiaoteng Cui, Chao Su, Lin Ge, Jie Shao, Lingbiao Xin, Juha Saarikettu, Mei Mei, Xi Yang, Minxin Wei, Olli Silvennoinen, Zhi Yao, Jinyan He and Jie Yang

      Article first published online: 26 JAN 2015 | DOI: 10.1111/febs.13186

  17. State-of-the-Art Reviews

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      BH3-only proteins: a 20-year stock-take

      Marcel Doerflinger, Jason A. Glab and Hamsa Puthalakath

      Article first published online: 26 JAN 2015 | DOI: 10.1111/febs.13190

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  18. Original Articles

    1. The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

      Niraj S. Bende, Sławomir Dziemborowicz, Volker Herzig, Venkatraman Ramanujam, Geoffrey W. Brown, Frank Bosmans, Graham M. Nicholson, Glenn F. King and Mehdi Mobli

      Article first published online: 23 JAN 2015 | DOI: 10.1111/febs.13189

  19. Review Articles

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  20. Upcoming Special Issue on Flavins and Flavoproteins

    1. Review Articles

      You have free access to this content
      Ultrafast fluorescence upconversion technique and its applications to proteins

      Haik Chosrowjan, Seiji Taniguchi and Fumio Tanaka

      Article first published online: 22 JAN 2015 | DOI: 10.1111/febs.13180

  21. Upcoming Special Issue: Epigenetics

    1. Review Articles

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      Epigenetic regulation of endothelial-cell-mediated vascular repair

      Sylvain Fraineau, Carmen G. Palii, David S. Allan and Marjorie Brand

      Article first published online: 14 JAN 2015 | DOI: 10.1111/febs.13183

  22. Reviews

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  23. Upcoming Special Issue: Epigenetics

    1. Review Articles

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      Noncoding RNAs as epigenetic mediators of skeletal muscle regeneration

      Gurjeev Sohi and Francis Jeffrey Dilworth

      Article first published online: 12 JAN 2015 | DOI: 10.1111/febs.13170

  24. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      5-hydroxymethylfurfural conversion by fungal aryl-alcohol oxidase and unspecific peroxygenase

      Juan Carro, Patricia Ferreira, Leonor Rodríguez, Alicia Prieto, Ana Serrano, Beatriz Balcells, Ana Ardá, Jesús Jiménez-Barbero, Ana Gutiérrez, René Ullrich, Martin Hofrichter and Angel T. Martínez

      Article first published online: 8 JAN 2015 | DOI: 10.1111/febs.13177

    2. Review Articles

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      Towards the free energy landscape for catalysis in mammalian nitric oxide synthases

      Nicole G. H. Leferink, Sam Hay, Stephen E. J. Rigby and Nigel S. Scrutton

      Article first published online: 26 DEC 2014 | DOI: 10.1111/febs.13171

  25. Upcoming Special Issue: Epigenetics

    1. Review Articles

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      High-wire act: the poised genome and cellular memory

      Deepika Puri, Hardik Gala, Rakesh Mishra and Jyotsna Dhawan

      Article first published online: 21 DEC 2014 | DOI: 10.1111/febs.13165

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      Epigenetic alterations in acute myeloid leukemias

      Parinaz Mehdipour, Fabio Santoro and Saverio Minucci

      Article first published online: 24 NOV 2014 | DOI: 10.1111/febs.13142

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      The many faces of long noncoding RNAs

      Alessandro Gardini and Ramin Shiekhattar

      Article first published online: 7 NOV 2014 | DOI: 10.1111/febs.13101

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      Role of PRC2-associated factors in stem cells and disease

      Pedro Vizán, Malte Beringer, Cecilia Ballaré and Luciano Di Croce

      Article first published online: 25 OCT 2014 | DOI: 10.1111/febs.13083

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      Epigenetic control of adult skeletal muscle stem cell functions

      Jessica Segalés, Eusebio Perdiguero and Pura Muñoz-Cánoves

      Article first published online: 21 OCT 2014 | DOI: 10.1111/febs.13065

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      Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity

      Laia Bosch-Presegué and Alejandro Vaquero

      Article first published online: 13 OCT 2014 | DOI: 10.1111/febs.13053

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    12. Original Articles

    13. Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics

      Susan L. Kloet, H. Irem Baymaz, Matthew Makowski, Vincent Groenewold, Pascal W. T. C. Jansen, Madeleine Berendsen, Hassin Niazi, Geert J. Kops and Michiel Vermeulen

      Article first published online: 11 SEP 2014 | DOI: 10.1111/febs.12972

    14. Review Articles

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      A new role for LOX and LOXL2 proteins in transcription regulation

      Ane Iturbide, Antonio García de Herreros and Sandra Peiró

      Article first published online: 6 SEP 2014 | DOI: 10.1111/febs.12961

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      Epigenetic regulation of adult stem cell function

      Lorenzo Rinaldi and Salvador Aznar Benitah

      Article first published online: 15 AUG 2014 | DOI: 10.1111/febs.12946

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