FEBS Journal

Cover image for Vol. 282 Issue 8

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Seamus Martin

Impact Factor: 3.986

ISI Journal Citation Reports © Ranking: 2013: 85/291 (Biochemistry & Molecular Biology)

Online ISSN: 1742-4658

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  1. 1 - 76
  1. Original Articles

    1. Binding proteins enhance specific uptake rate by increasing the substrate–transporter encounter rate

      Evert Bosdriesz, Stefanía Magnúsdóttir, Frank J. Bruggeman, Bas Teusink and Douwe Molenaar

      Article first published online: 24 APR 2015 | DOI: 10.1111/febs.13289

  2. Review Articles

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      Molecular features of the sortase enzyme family

      William J. Bradshaw, Abigail H. Davies, Christopher J. Chambers, April K. Roberts, Clifford C. Shone and K. Ravi Acharya

      Article first published online: 24 APR 2015 | DOI: 10.1111/febs.13288

  3. Original Articles

    1. N-terminally extended analogues of the K+ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3

      Shih C. Chang, Redwan Huq, Sandeep Chhabra, Christine Beeton, Michael W. Pennington, Brian J. Smith and Raymond S. Norton

      Article first published online: 23 APR 2015 | DOI: 10.1111/febs.13294

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      Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation

      Taeko Kobayashi, Yumiko Iwamoto, Kazuhiro Takashima, Akihiro Isomura, Yoichi Kosodo, Koichi Kawakami, Tomoki Nishioka, Kozo Kaibuchi and Ryoichiro Kageyama

      Article first published online: 23 APR 2015 | DOI: 10.1111/febs.13290

    3. Single active-site mutants are sufficient to enhance serine:pyruvate α-transaminase activity in an ω-transaminase

      Dawid Deszcz, Pierre Affaticati, Nadine Ladkau, Alex Gegel, John M. Ward, Helen C. Hailes and Paul A. Dalby

      Article first published online: 23 APR 2015 | DOI: 10.1111/febs.13293

  4. State-of-the-Art Reviews

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      STAT3 the oncogene – still eluding therapy?

      Matthew S. Wake and Christine J. Watson

      Article first published online: 22 APR 2015 | DOI: 10.1111/febs.13285

  5. Original Articles

    1. A computational strategy for altering an enzyme in its cofactor preference to NAD(H) and/or NADP(H)

      Dongbing Cui, Lujia Zhang, Shuiqin Jiang, Zhiqiang Yao, Bei Gao, Jinping Lin, Y. Adam Yuan and Dongzhi Wei

      Article first published online: 22 APR 2015 | DOI: 10.1111/febs.13282

    2. Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice

      Tim Hendrikx, Mike L. J. Jeurissen, Patrick J. van Gorp, Marion J. Gijbels, Sofie M. A. Walenbergh, Tom Houben, Rick van Gorp, Chantal C. Pöttgens, Rinke Stienstra, Mihai G. Netea, Marten H. Hofker, Marjo M. P. C. Donners and Ronit Shiri-Sverdlov

      Article first published online: 20 APR 2015 | DOI: 10.1111/febs.13279

  6. Special Issue: Epigenetics

    1. Introduction

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      Special Issue: Epigenetics Introduction

      Pura Muñoz-Cánoves and Luciano Di Croce

      Article first published online: 20 APR 2015 | DOI: 10.1111/febs.13281

  7. Original Articles

    1. Novel familial dilated cardiomyopathy mutation in MYL2 affects the structure and function of myosin regulatory light chain

      Wenrui Huang, Jingsheng Liang, Chen-Ching Yuan, Katarzyna Kazmierczak, Zhiqun Zhou, Ana Morales, Kim L. McBride, Sara M. Fitzgerald-Butt, Ray E. Hershberger and Danuta Szczesna-Cordary

      Article first published online: 16 APR 2015 | DOI: 10.1111/febs.13286

  8. State-of-the-Art Reviews

    1. Proteomics beyond trypsin

      Liana Tsiatsiani and Albert J. R. Heck

      Article first published online: 14 APR 2015 | DOI: 10.1111/febs.13287

      This article is accompanied by a podcast, listen now. Or listen in iTunes.

  9. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      You have full text access to this OnlineOpen article
      The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase

      Tomoko Nishino, Ken Okamoto, Yuko Kawaguchi, Tomohiro Matsumura, Bryan T. Eger, Emil F. Pai and Takeshi Nishino

      Article first published online: 13 APR 2015 | DOI: 10.1111/febs.13277

  10. Minireviews

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  11. Original Articles

    1. PKC-mediated inhibitory feedback of the cholecystokinin 1 receptor controls the shape of oscillatory Ca2+ signals

      Peter H. G. M. Willems, Jürgen Pahle, Xenia L. Stalpers, Douaa Mugahid, Alexander Nikolaew, Werner J. H. Koopman and Ursula Kummer

      Article first published online: 13 APR 2015 | DOI: 10.1111/febs.13267

  12. State-of-the-Art Reviews

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      The impact of hypoxia on bacterial infection

      Kirsten Schaffer and Cormac T. Taylor

      Article first published online: 13 APR 2015 | DOI: 10.1111/febs.13270

  13. Original Articles

    1. Enzyme kinetics: the whole picture reveals hidden meanings

      Maria F. Pinto, Berta N. Estevinho, Rosa Crespo, Fernando A. Rocha, Ana M. Damas and Pedro M. Martins

      Article first published online: 13 APR 2015 | DOI: 10.1111/febs.13275

    2. Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies

      Inês Cardoso, Jorunn Stamnaes, Jan Terje Andersen, Gerry Melino, Rasmus Iversen and Ludvig M. Sollid

      Article first published online: 13 APR 2015 | DOI: 10.1111/febs.13276

    3. The three-dimensional structure of VIM-31 – a metallo-β-lactamase from Enterobacter cloacae in its native and oxidized form

      Michaël B. Kupper, Konrad Herzog, Sandra Bennink, Philipp Schlömer, Pierre Bogaerts, Youri Glupczynski, Rainer Fischer, Carine Bebrone and Kurt M. Hoffmann

      Article first published online: 13 APR 2015 | DOI: 10.1111/febs.13283

    4. GM130 is a parallel tetramer with a flexible rod-like structure and N–terminally open (Y-shaped) and closed (I-shaped) conformations

      Ryuichi Ishida, Akitsugu Yamamoto, Kazuhisa Nakayama, Miwa Sohda, Yoshio Misumi, Takuo Yasunaga and Nobuhiro Nakamura

      Article first published online: 11 APR 2015 | DOI: 10.1111/febs.13271

  14. State-of-the-Art Reviews

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      Rethinking the capsid proteins of enveloped viruses: multifunctionality from genome packaging to genome transfection

      João M. Freire, Nuno C. Santos, Ana Salomé Veiga, Andrea T. Da Poian and Miguel A. R. B. Castanho

      Article first published online: 11 APR 2015 | DOI: 10.1111/febs.13274

      This article is accompanied by a podcast, listen now. Or listen in iTunes.

  15. Original Articles

    1. Rebamipide suppresses TNF-α-mediated inflammatory reaction in vitro and attenuates the severity of dermatitis in mice

      Weiwei Li, Yunpeng Zhao, Xiangling Xu, Weiyuan Ma, Peng Gao, Yan Wang, Ke Liang and Ruifeng Li

      Article first published online: 11 APR 2015 | DOI: 10.1111/febs.13278

    2. GxxxG motifs hold the TIM23 complex together

      Keren Demishtein-Zohary, Milit Marom, Walter Neupert, Dejana Mokranjac and Abdussalam Azem

      Article first published online: 10 APR 2015 | DOI: 10.1111/febs.13266

    3. Inventory of the GH70 enzymes encoded by Leuconostoc citreum NRRL B-1299 – identification of three novel α-transglucosylases

      Delphine Passerini, Marlène Vuillemin, Lisa Ufarté, Sandrine Morel, Valentin Loux, Catherine Fontagné-Faucher, Pierre Monsan, Magali Remaud-Siméon and Claire Moulis

      Article first published online: 8 APR 2015 | DOI: 10.1111/febs.13261

    4. Efficient transposition of the youngest miniature inverted repeat transposable element family of yellow fever mosquito in yeast

      Isam Fattash, Chia-Ni Lee, Kaiguo Mo and Guojun Yang

      Article first published online: 8 APR 2015 | DOI: 10.1111/febs.13257

      This article is accompanied by a podcast, listen now. Or listen in iTunes.

    5. Structural insights into the inhibition of cellobiohydrolase Cel7A by xylo-oligosaccharides

      Majid Haddad Momeni, Wimal Ubhayasekera, Mats Sandgren, Jerry Ståhlberg and Henrik Hansson

      Article first published online: 8 APR 2015 | DOI: 10.1111/febs.13265

    6. Novel steps in the autophagic-lysosomal pathway

      Frank Sætre, Linda Korseberg Hagen, Nikolai Engedal and Per O. Seglen

      Article first published online: 8 APR 2015 | DOI: 10.1111/febs.13268

  16. Review Articles

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      VHR/DUSP3 phosphatase: structure, function and regulation

      Karolina Pavic, Guangyou Duan and Maja Köhn

      Article first published online: 1 APR 2015 | DOI: 10.1111/febs.13263

  17. Original Articles

    1. Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A

      Jaime Tomé-Amat, Elías Herrero-Galán, Mercedes Oñaderra, Álvaro Martínez-del-Pozo, José G. Gavilanes and Javier Lacadena

      Article first published online: 27 MAR 2015 | DOI: 10.1111/febs.13262

  18. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      cis-cyclopropylamines as mechanism-based inhibitors of monoamine oxidases

      Thomas Malcomson, Kemal Yelekci, Maria Teresa Borrello, A. Ganesan, Elena Semina, Norbert De Kimpe, Sven Mangelinckx and Rona R. Ramsay

      Article first published online: 27 MAR 2015 | DOI: 10.1111/febs.13260

  19. Original Articles

    1. Protein disulfide isomerase as a novel target for cyclopentenone prostaglandins: implications for hypoxic ischemic injury

      Hao Liu, Jie Chen, Wenjin Li, Marie E. Rose, Sunita N. Shinde, Manimalha Balasubramani, Guy T. Uechi, Bülent Mutus, Steven H. Graham and Robert W. Hickey

      Article first published online: 27 MAR 2015 | DOI: 10.1111/febs.13259

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  20. State-of-the-Art Reviews

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      Lysosomal proteins in cell death and autophagy

      Michaela Mrschtik and Kevin M. Ryan

      Article first published online: 23 MAR 2015 | DOI: 10.1111/febs.13253

  21. Original Articles

    1. dUTPase expression correlates with cell division potential in Drosophila melanogaster

      András Horváth, Júlia Batki, László Henn, Tamás Lukacsovich, Gergely Róna, Miklós Erdélyi and Beáta G. Vértessy

      Article first published online: 21 MAR 2015 | DOI: 10.1111/febs.13255

    2. Kinetic mechanism of l–α–glycerophosphate oxidase from Mycoplasma pneumoniae

      Somchart Maenpuen, Pratchaya Watthaisong, Pacharee Supon, Jeerus Sucharitakul, Derek Parsonage, P. Andrew Karplus, Al Claiborne and Pimchai Chaiyen

      Article first published online: 20 MAR 2015 | DOI: 10.1111/febs.13247

    3. Crystal structure of LptH, the periplasmic component of the lipopolysaccharide transport machinery from Pseudomonas aeruginosa

      Michela Bollati, Riccardo Villa, Louise J. Gourlay, Mattia Benedet, Gianni Dehò, Alessandra Polissi, Alberto Barbiroli, Alessandra M. Martorana, Paola Sperandeo, Martino Bolognesi and Marco Nardini

      Article first published online: 20 MAR 2015 | DOI: 10.1111/febs.13254

    4. An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions

      Meital Abayev, Adi Moseri, Oren Tchaicheeyan, Naama Kessler, Boris Arshava, Fred Naider, Tali Scherf and Jacob Anglister

      Article first published online: 18 MAR 2015 | DOI: 10.1111/febs.13243

    5. The yeast ζ-crystallin/NADPH:quinone oxidoreductase (Zta1p) is under nutritional control by the target of rapamycin pathway and is involved in the regulation of argininosuccinate lyase mRNA half-life

      Eva Crosas, Lauro Sumoy, Eva González, Maykelis Díaz, Salvador Bartolomé, Jaume Farrés, Xavier Parés, Josep Antoni Biosca and María Rosario Fernández

      Article first published online: 18 MAR 2015 | DOI: 10.1111/febs.13246

    6. A high molecular mass zinc transporter MTP12 forms a functional heteromeric complex with MTP5 in the Golgi in Arabidopsis thaliana

      Takashi Fujiwara, Miki Kawachi, Yori Sato, Haruki Mori, Natsumaro Kutsuna, Seiichiro Hasezawa and Masayoshi Maeshima

      Article first published online: 18 MAR 2015 | DOI: 10.1111/febs.13252

  22. State-of-the-Art Reviews

    1. You have full text access to this OnlineOpen article
      Parkin structure and function

      Marjan Seirafi, Guennadi Kozlov and Kalle Gehring

      Article first published online: 16 MAR 2015 | DOI: 10.1111/febs.13249

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      High-throughput screens in mammalian cells using the CRISPR-Cas9 system

      Jingyu Peng, Yuexin Zhou, Shiyou Zhu and Wensheng Wei

      Article first published online: 16 MAR 2015 | DOI: 10.1111/febs.13251

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  23. Original Articles

    1. Spine and test skeletal matrices of the Mediterranean sea urchin Arbacia lixula – a comparative characterization of their sugar signature

      Julia M. Kanold, Nathalie Guichard, Françoise Immel, Laurent Plasseraud, Marion Corneillat, Gérard Alcaraz, Franz Brümmer and Frédéric Marin

      Article first published online: 14 MAR 2015 | DOI: 10.1111/febs.13242

  24. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

      Structure and proposed mechanism of l-α-glycerophosphate oxidase from Mycoplasma pneumoniae

      Callia K. Elkhal, Kelsey M. Kean, Derek Parsonage, Somchart Maenpuen, Pimchai Chaiyen, Al Claiborne and P. Andrew Karplus

      Article first published online: 14 MAR 2015 | DOI: 10.1111/febs.13233

  25. Original Articles

    1. MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic lymphocytic leukemia

      Pradeep Kumar Kopparapu, Caroline Miranda, Linda Fogelstrand, Kankadeb Mishra, Per-Ola Andersson, Chandrasekhar Kanduri and Meena Kanduri

      Article first published online: 9 MAR 2015 | DOI: 10.1111/febs.13245

  26. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

    2. Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction

      Domen Zafred, Barbara Steiner, Andrea R. Teufelberger, Altijana Hromic, P. Andrew Karplus, Christopher J. Schofield, Silvia Wallner and Peter Macheroux

      Article first published online: 24 FEB 2015 | DOI: 10.1111/febs.13212

    3. Aromatic stacking interactions govern catalysis in aryl-alcohol oxidase

      Patricia Ferreira, Aitor Hernández-Ortega, Fátima Lucas, Juan Carro, Beatriz Herguedas, Kenneth W. Borrelli, Victor Guallar, Angel T. Martínez and Milagros Medina

      Article first published online: 23 FEB 2015 | DOI: 10.1111/febs.13221

    4. Crystal structures of apo-DszC and FMN-bound DszC from Rhodococcus erythropolis D-1

      Li-Jun Guan, Woo Cheol Lee, Shipeng Wang, Takashi Ohshiro, Yoshikazu Izumi, Jun Ohtsuka and Masaru Tanokura

      Article first published online: 11 FEB 2015 | DOI: 10.1111/febs.13216

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    6. Review Articles

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      Ultrafast fluorescence upconversion technique and its applications to proteins

      Haik Chosrowjan, Seiji Taniguchi and Fumio Tanaka

      Article first published online: 22 JAN 2015 | DOI: 10.1111/febs.13180

  27. Upcoming Special Issue: Epigenetics

    1. Review Articles

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      Epigenetic regulation of endothelial-cell-mediated vascular repair

      Sylvain Fraineau, Carmen G. Palii, David S. Allan and Marjorie Brand

      Article first published online: 14 JAN 2015 | DOI: 10.1111/febs.13183

  28. Reviews

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  29. Upcoming Special Issue: Epigenetics

    1. Review Articles

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  30. Upcoming Special Issue on Flavins and Flavoproteins

    1. Original Articles

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      5-hydroxymethylfurfural conversion by fungal aryl-alcohol oxidase and unspecific peroxygenase

      Juan Carro, Patricia Ferreira, Leonor Rodríguez, Alicia Prieto, Ana Serrano, Beatriz Balcells, Ana Ardá, Jesús Jiménez-Barbero, Ana Gutiérrez, René Ullrich, Martin Hofrichter and Angel T. Martínez

      Article first published online: 8 JAN 2015 | DOI: 10.1111/febs.13177

    2. Review Articles

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      Towards the free energy landscape for catalysis in mammalian nitric oxide synthases

      Nicole G. H. Leferink, Sam Hay, Stephen E. J. Rigby and Nigel S. Scrutton

      Article first published online: 26 DEC 2014 | DOI: 10.1111/febs.13171

  31. Upcoming Special Issue: Epigenetics

    1. Review Articles

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      High-wire act: the poised genome and cellular memory

      Deepika Puri, Hardik Gala, Rakesh Mishra and Jyotsna Dhawan

      Article first published online: 21 DEC 2014 | DOI: 10.1111/febs.13165

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      Epigenetic alterations in acute myeloid leukemias

      Parinaz Mehdipour, Fabio Santoro and Saverio Minucci

      Article first published online: 24 NOV 2014 | DOI: 10.1111/febs.13142

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      The many faces of long noncoding RNAs

      Alessandro Gardini and Ramin Shiekhattar

      Article first published online: 7 NOV 2014 | DOI: 10.1111/febs.13101

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      Role of PRC2-associated factors in stem cells and disease

      Pedro Vizán, Malte Beringer, Cecilia Ballaré and Luciano Di Croce

      Article first published online: 25 OCT 2014 | DOI: 10.1111/febs.13083

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      Epigenetic control of adult skeletal muscle stem cell functions

      Jessica Segalés, Eusebio Perdiguero and Pura Muñoz-Cánoves

      Article first published online: 21 OCT 2014 | DOI: 10.1111/febs.13065

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    11. You have free access to this content
    12. Original Articles

    13. Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics

      Susan L. Kloet, H. Irem Baymaz, Matthew Makowski, Vincent Groenewold, Pascal W. T. C. Jansen, Madeleine Berendsen, Hassin Niazi, Geert J. Kops and Michiel Vermeulen

      Article first published online: 11 SEP 2014 | DOI: 10.1111/febs.12972

    14. Review Articles

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      A new role for LOX and LOXL2 proteins in transcription regulation

      Ane Iturbide, Antonio García de Herreros and Sandra Peiró

      Article first published online: 6 SEP 2014 | DOI: 10.1111/febs.12961

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      Epigenetic regulation of adult stem cell function

      Lorenzo Rinaldi and Salvador Aznar Benitah

      Article first published online: 15 AUG 2014 | DOI: 10.1111/febs.12946

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