FEBS Journal

Most Cited

Top cited FEBS Journal papers 2012 (two years from publication period April 2010 – September 2010)

Mysterious oligomerization of the amyloidogenic proteins
Vladimir N. Uversky
FEBS Journal 277, 2940–2953, July 2010

Making sense of G-quadruplex and i-motif functions in oncogene promoters
Tracy A. Brooks, Samantha Kendrick, Laurence Hurley
FEBS Journal 277, 3459–3469, September 2010

Tumor suppressor p16^INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model
Hugo Sanchez-Ruderisch, Christian Fischer, Katharina M. Detjen, Martina Welzel, Anja Wimmel, Joachim C. Manning, Sabine André, Hans-Joachim Gabius
FEBS Journal 277, 3552–3563, September 2010

Priv.-Doz. Dr. Sabine André and Prof. Dr. H. C. Hans J. Gabius, based at the University of Munich, devote their research to glycosciences. The highlighted manuscript (together with its companion articles in FEBS Journal in 2007 and 2012) describe how a tumor suppressor reprograms glycosylation to trigger anoikis.

MicroRNAs and the regulation of fibrosis
Xiaoying Jiang, Eleni Tsitsiou, Sarah E. Herrick, Mark A. Lindsay
FEBS Journal 277, 2015–2021, May 2010

Dr Xiaoying Jiang is Associate Professor in the Department of Genetics and Molecular Biology, at the School of Medicine, Xi’an Jiaotong University, China. Her current research focuses on the identification and characterization of novel non-coding RNAs in cardiac fibrosis. Professor Lindsay, Chair/Professor of Molecular Pharmacology at the University of Bath, has been involved in developing RNA interference-based therapeutics and characterising the biological role of microRNAs and long non-coding RNAs in the immune response and respiratory disease.

Nuclear factor TDP-43 can affect selected microRNA levels
Emanuele Buratti, Laura De Conti, Cristiana Stuani, Maurizio Romano, Marco Baralle, Francisco Baralle
FEBS Journal 277, 2268–2281, May 2010

Emanuele Buratti is currently a Staff Research Scientist at the International Centre for Genetic Engineering and Biotechnology in Trieste. Previously, he studied at the University of Trieste for a Ph.D. in Biochemistry. Dr. Buratti’s principal areas of expertise are the investigation of RNA splicing processes.

Progressive accumulation of amyloid-β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins
Emiley Pham, Leslie Crews, Kiren Ubhi, Lawrence Hansen, Anthony Adame, Anna Cartier, David Salmon, Douglas Galasko, Sarah Michael, Jeffrey N. Savas, John R. Yates, Charles Glabe, Eliezer Masliah
FEBS Journal 277, 3051–3067, July 2010

The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of β-glucosidase
Richie Khanna, Elfrida R. Benjamin, Lee Pellegrino, Adriane Schilling, Brigitte A. Rigat, Rebecca Soska, Hadis Nafar, Brian E. Ranes, Jessie Feng, Yi Lun, Allan C. Powe, David J. Palling, Brandon A. Wustman, Raphael Schiffmann, Don J. Mahuran, David J. Lockhart, Kenneth J. Valenzano
FEBS Journal 277, 1618–1638, April 2010

Richie Khanna, PhD, is a Principal Investigator in the Department of Pharmacology at Amicus Therapeutics. She received her PhD from the University of Delhi, India, and conducted post-doctoral research in the Universities of Tufts and Rutgers. Her research work at Amicus is focused on evaluating the in vivo effects of pharmacological chaperones when used alone or in combination with recombinant human enzymes for lysosomal storage disorders.

Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing
Khairul I. Ansari, Subhrangsu S. Mandal
FEBS Journal 277, 1790–1804, April 2010

Subhrangsu Mandal is an Associate Professor of Biochemistry at the University of Texas at Arlington. He received his PhD from the Indian Institute of Science and pursued his postdoctoral studies at the University of Alberta and the University of Medicine and Dentistry of New Jersey (HHMI). Currently, his laboratory is investigating the epigenetic aspects of human gene regulation, chromatin dynamics, steroid hormone signalling, endocrine disruption, cholesterol homeostasis, hypoxia signalling and tumorigenesis. He is also developing drugs for the treatment of cardiovascular disease and cancer.

Sugar signalling and antioxidant network connections in plant cells
Mohammad Reza Bolouri-Moghaddam, Katrien Le Roy, Li Xiang, Filip Rolland, Wim Van den Ende
FEBS Journal 277, 2022–2037, May 2010

Dr Wim Van den Ende is Professor at the KU Leuven, Belgium. His interests are in sugar metabolism, sugar signaling and sugar-mediated stress tolerance mechanisms in plants, with additional focus on the prebiotic, antioxidant and immunomodulatory properties of plant-derived sugars and phenolic compounds.

Structure, location and interactions of G-quadruplexes
Julian L. Huppert
FEBS Journal 277, 3452–3458, September 2010

Dr Julian Huppert is currently the Member of Parliament for Cambridge, and is one of very few scientists in the House of Commons. He used to be an RCUK Academic Fellow in Computational Biology at the Cavendish Laboratory, University of Cambridge, and worked on DNA structure and function.