Chemical Biology & Drug Design

Cover image for Vol. 87 Issue 2

Edited By: David Selwood

Impact Factor: 2.485

ISI Journal Citation Reports © Ranking: 2014: 28/59 (Chemistry Medicinal); 164/290 (Biochemistry & Molecular Biology)

Online ISSN: 1747-0285

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Editor's Choice

Rational Design of Glycomimetic Compounds Targeting the Saccharomyces cerevisiae Transglycosylase Gas2

Ignacio Delso*, Jessika Valero-González, Eduardo Marca, Tomás Tejero, Ramón Hurtado-Guerrero* and Pedro Merino


A series of docking-guided glycomimetics have been synthesized and evaluated by fluorescence spectroscopy and STD-NMR experiments. The studies revealed that a minimum of three glucose units linked via a β-(1,3) linkage are required for achieving molecular recognition at the binding donor site.

This issue’s Editor’s Choice was chosen by Roberta Melander

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