Chemical Biology & Drug Design

Cover image for Vol. 85 Issue 6

Edited By: David Selwood

Impact Factor: 2.507

ISI Journal Citation Reports © Ranking: 2013: 28/58 (Chemistry Medicinal); 173/291 (Biochemistry & Molecular Biology)

Online ISSN: 1747-0285

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Editor's Choice

A Fluorescent Probe for Imaging p53–MDM2 Protein–Protein Interaction

Zhenzhen Liu, Zhenyuan Miao, Jin Li, Kun Fang, Chunlin Zhuang, Lupei Du, Chunquan Sheng and Minyong Li

A Fluorescent Probe

A novel small-molecule fluorescent probe was developed to detect and image the p53–MDM2 interaction based on an environment-sensitive fluorophore, N,N-dimethyl-1,8-naphthalimide. After extensive biological examination, this probe L1 exhibited practical activity and selectivity in vitro and in cellulo.

This issue’s Editor’s Choice was chosen by David Selwood

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Meet the Editorial Team

We are pleased to announce that a member of our Editorial Board, Jurgen Bajorath, has won the 2015 Skolnik Award for his outstanding contributions to information science.

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