Chemical Biology & Drug Design

Most Cited

Read the most cited articles in 2012
(articles published in 2010-2012)

Structure-based Drug Metabolism Predictions for Drug Design
Hao Sun, Dennis O. Scott

Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance
Tianjun Zhou et al.

Probing the α-Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis
Zuojun Guo et al.

Fragment-Based Screen against HIV Protease
Alexander L. Perryman et al.

Insight into Amyloid Structure Using Chemical Probes
Ashley A. Reinke, Jason E. Gestwicki

Mapping the Druggable Allosteric Space of G-Protein Coupled Receptors: a Fragment-Based Molecular Dynamics Approach
Anthony Ivetac, J. Andrew McCammon

Chemogenetic Analysis of Human Protein Methyltransferases
Victoria M. Richon et al.

Comprehensive Analysis of Single-and Multi-Target Activity Cliffs Formed by Currently Available Bioactive Compounds
Anne M. Wassermann, Dilyana Dimova, Jürgen Bajorath

Antimicrobial Activity of Short, Synthetic Cationic Lipopeptides
Garry Laverty, Martin McLaughlin, Christopher Shaw, Sean P. Gorman, Brendan F. Gilmore

An Alternative Purification Method for Human Serum Paraoxonase 1 and its Interactions with Sulfonamides
Deniz Ekinci, Murat Şentürk, Şükrü Beydemir, Ömar İrfan Küfrevioğlu, Claudiu T. Supuran