Influence of Trans Fat on Skin Damage in First-Generation Rats Exposed to UV Radiation
Raquel Cristine S. Barcelos, Luciana T. Vey, Hecson Jesser Segat, Dalila M. Benvegnú, Fabíola Trevizol, Karine Roversi, Katiane Roversi, Verônica T. Dias, Geisa S. Dolci, Fábio T. Kuhn, Jaqueline Piccolo, Juliana CristinaVeit, Tatiana Emanuelli and Marilise E. Bürger
Article first published online: 20 JAN 2015 | DOI: 10.1111/php.12414
Metabolism of trans fat by COX and LOX: The dietary intake of trans fat favors the synthesis of biologically active prostanoids produced during inflammatory processes. After ultraviolet radiation exposure, trans fat supplementation, which is rich in trans fatty acids (TFA), increases the skin thickness, reactive species generation and decreases the skin antioxidant defenses.