High Final Energy of Low-Level Gallium Arsenide Laser Therapy Enhances Skeletal Muscle Recovery without a Positive Effect on Collagen Remodeling
Carlos Eduardo Assumpção de Freitas, Raquel Santilone Bertaglia, Ivan José Vechetti Júnior, Edson Assunção Mareco, Rondinelle Artur Simões Salomão, Tassiana Gutierrez de Paula, Gisele Alborghetti Nai, Robson Francisco Carvalho, Francis Lopes Pacagnelli and Maeli Dal-Pai-Silva
Article first published online: 28 MAR 2015 | DOI: 10.1111/php.12446
This study investigated the effects of low-level laser therapy (LLLT) at a high final energy (4.8 J) during muscle regeneration after cryoinjury. Gallium Arsenide (GaAs, 904 nm) laser applied for 5 days in two points of the lesion resulted in a significant decrease in the TNF-α and myogenin, without change in the TGF-β gene expression. The Injured/LLLT group presented a higher number of regenerating fibers and fewer degenerating fibers without changes in the collagen remodeling. The results suggest that the GaAs laser at a high final energy (4.8 J) promotes muscle recovery without changing the collagen remodeling.