Journal of Pharmacy and Pharmacology

Cover image for Vol. 69 Issue 2

Early View (Online Version of Record published before inclusion in an issue)

Edited By: D Jones, Queen's University of Belfast, UK

Impact Factor: 2.363

ISI Journal Citation Reports © Ranking: 2015: 127/255 (Pharmacology & Pharmacy)

Online ISSN: 2042-7158

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  1. 1 - 47
  1. Research Papers

    1. Complexation of oxethazaine with 2-hydroxypropyl-β-cyclodextrin: increased drug solubility, decreased cytotoxicity and analgesia at inflamed tissues

      Andressa R. Prado, Fabiano Yokaichiya, Margareth Kazuyo Kobayashi Dias Franco, Camila Morais Gonçalves da Silva, Laura Oliveira-Nascimento, Michelle Franz-Montan, Maria C. Volpato, Luís F. Cabeça and Eneida de Paula

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12703

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      Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux

      Anna Subbotina, Aina W. Ravna, Roy A. Lysaa, Ruben Abagyan, Ryszard Bugno and Georg Sager

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12693

    3. Cytotoxic analysis and chemical characterization of fractions of the hydroalcoholic extract of the Euterpe oleracea Mart. seed in the MCF-7 cell line

      Dayanne da S. Freitas, José A. Morgado-Díaz, Adriana S. Gehren, Flávia C. B. Vidal, Raquel Maria T. Fernandes, Wanderson Romão, Lilian V. Tose, Fabiola N. S. Frazão, Maria Célia P. Costa, Dulcelena F. Silva and Maria do Desterro S. B. Nascimento

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12679

    4. Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness

      Carlos T. M. Moura, Francisco J. Batista-Lima, Teresinha S. Brito, Alfredo A. V. Silva, Luan C. Ferreira, Cássia R. Roque, Karoline S. Aragão, Alexandre Havt, Francisco N. Fonseca, Luzia K. A. M. Leal and Pedro J. C. Magalhães

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12689

  2. Reviews

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      Biopharmaceutical Informatics: supporting biologic drug development via molecular modelling and informatics

      Sandeep Kumar, Nikolay V. Plotnikov, Jason C. Rouse and Satish K. Singh

      Version of Record online: 3 FEB 2017 | DOI: 10.1111/jphp.12700

  3. Research Papers

    1. In-vitro evaluation of enteric coated insulin tablets containing absorption enhancer and enzyme inhibitor

      Chun Y. Wong, Jorge Martinez, Revathy Carnagarin and Crispin R. Dass

      Version of Record online: 3 FEB 2017 | DOI: 10.1111/jphp.12694

    2. Fucosterol, isolated from Ecklonia stolonifera, inhibits adipogenesis through modulation of FoxO1 pathway in 3T3-L1 adipocytes

      Ji-Hyun Lee, Hyun Ah Jung, Min Jae Kang, Jae Sue Choi and Gun-Do Kim

      Version of Record online: 30 JAN 2017 | DOI: 10.1111/jphp.12684

    3. Orcinol derivative compound with antioxidant properties protects Langerhans islets against streptozotocin damage

      Nancy M.V. Sánchez-Lira, Angélica Morales-Miranda, Gustavo García de la Mora, Juan Carlos León Contreras, Ignacio González-Sánchez, Norma Valencia, Marco Cerbón and Sumiko Morimoto

      Version of Record online: 30 JAN 2017 | DOI: 10.1111/jphp.12696

  4. Reviews

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  5. Research Papers

    1. In-vitro and in-vivo evaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system

      Gerard Esteban, Jolien Van Schoors, Ping Sun, Ann Van Eeckhaut, José Marco-Contelles, Ilse Smolders and Mercedes Unzeta

      Version of Record online: 30 JAN 2017 | DOI: 10.1111/jphp.12697

    2. The essential oil from the fruits of the Brazilian spice Xylopia sericea A. St.-Hil. presents expressive in-vitro antibacterial and antioxidant activity

      Renata de F. Mendes, Nícolas de C. C. Pinto, Josiane M. da Silva, Jucélia B. da Silva, Raquel C. dos S. Hermisdorf, Rodrigo L. Fabri, Luciana M. Chedier and Elita Scio

      Version of Record online: 30 JAN 2017 | DOI: 10.1111/jphp.12698

  6. Reviews

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      Chinese herbal drugs for the treatment of diabetic retinopathy

      Tapan Behl and Anita Kotwani

      Version of Record online: 26 JAN 2017 | DOI: 10.1111/jphp.12683

  7. Research Papers

    1. Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions

      Thuy Tran, Dimitrios G. Fatouros, Maria Vertzoni, Christos Reppas and Anette Müllertz

      Version of Record online: 20 JAN 2017 | DOI: 10.1111/jphp.12686

    2. Limitations of polyethylene glycol-induced precipitation as predictive tool for protein solubility during formulation development

      Melanie Hofmann, Matthias Winzer, Christian Weber and Henning Gieseler

      Version of Record online: 20 JAN 2017 | DOI: 10.1111/jphp.12699

    3. Influence of P-glycoprotein on the disposition of fexofenadine and its enantiomers

      Fei Li, Karyn D. Howard and Michael J. Myers

      Version of Record online: 16 JAN 2017 | DOI: 10.1111/jphp.12687

    4. Bacteriophage formulated into a range of semisolid and solid dosage forms maintain lytic capacity against isolated cutaneous and opportunistic oral bacteria

      Teagan L. Brown, Tereen Thomas, Jessica Odgers, Steve Petrovski, Marion Joy Spark and Joseph Tucci

      Version of Record online: 29 DEC 2016 | DOI: 10.1111/jphp.12673

  8. Reviews

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      A mini-review of non-parenteral clonidine preparations for paediatric sedation

      Sara M. Hanning, Mine Orlu Gul, Irmgard Toni, Antje Neubert, Catherine Tuleu and on behalf of the CloSed Consortium

      Version of Record online: 29 DEC 2016 | DOI: 10.1111/jphp.12662

  9. Research Papers

    1. Accuracy of tablet splitting and liquid measurements: an examination of who, what and how

      Dana Abu-Geras, Dunja Hadziomerovic, Andrew Leau, Ramzan Nazim Khan, Sajni Gudka, Cornelia Locher, Maryam Razaghikashani and Lee Yong Lim

      Version of Record online: 28 DEC 2016 | DOI: 10.1111/jphp.12671

    2. Prolonged-release minitablets with carbamazepine – preliminary observations in vitro

      Magdalena Dzajkowska, Kotlowska Hanna, Madanecka Anna, Szczepanska Maja, Doniza Dagmara, Sosnowicz Anna and Sznitowska Malgorzata

      Version of Record online: 20 DEC 2016 | DOI: 10.1111/jphp.12670

  10. Reviews

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      A review of the protective role of melatonin during phosphine-induced cardiotoxicity: focus on mitochondrial dysfunction, oxidative stress and apoptosis

      Mohammad Hossein Asghari, Mohammad Abdollahi, Marcos Roberto de Oliveira and Seyed Mohammad Nabavi

      Version of Record online: 20 DEC 2016 | DOI: 10.1111/jphp.12682

  11. Research Papers

    1. Oleanolic acid rejuvenates testicular function through attenuating germ cell DNA damage and apoptosis via deactivation of NF-κB, p53 and p38 signalling pathways

      Haixia Zhao, Jing Liu, Laixin Song, Zhencai Liu, Guifang Han, Ding Yuan, Ting Wang, Yaoyan Dun, Zhiyong Zhou, Zhaoqi Liu, Yongjun Wang and Changcheng Zhang

      Version of Record online: 9 DEC 2016 | DOI: 10.1111/jphp.12668

  12. Reviews

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      Effects of localized interactions and surface properties on stability of protein-based therapeutics

      Brittney J. Mills and Jennifer S. Laurence Chadwick

      Version of Record online: 10 NOV 2016 | DOI: 10.1111/jphp.12658

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      Palliative medicines for children – a new frontier in paediatric research

      Liz Jamieson, Ian C. K. Wong, Finella Craig, Nanna Christiansen, Karen Brombley, Catherine Tuleu and Emily Harrop

      Version of Record online: 13 OCT 2016 | DOI: 10.1111/jphp.12615

  13. Research Papers

    1. Physical compatibility of total parenteral nutrition and drugs in Y-site administration to children from neonates to adolescents

      Vigdis Staven, Herra Iqbal, Siri Wang, Ingrid Grønlie and Ingunn Tho

      Version of Record online: 7 OCT 2016 | DOI: 10.1111/jphp.12647

  14. Reviews

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  15. Research Papers

    1. Challenge of paediatric compounding to solid dosage forms sachets and hard capsules – Finnish perspective

      Mia Sivén, Satu Kovanen, Outi Siirola, Tuomas Hepojoki, Sari Isokirmo, Niina Laihanen, Tiina Eränen, Jukka Pellinen and Anne M. Juppo

      Version of Record online: 5 OCT 2016 | DOI: 10.1111/jphp.12648

    2. Microparticle surface layering through dry coating: impact of moisture content and process parameters on the properties of orally disintegrating tablets

      Hamad Alyami, Jasdip Koner, Eman Z. Dahmash, James Bowen, David Terry and Afzal R. Mohammed

      Version of Record online: 2 OCT 2016 | DOI: 10.1111/jphp.12623

    3. Formulation of orodispersible films for paediatric therapy: investigation of feasibility and stability for tetrabenazine as drug model

      Zoé Senta-Loys, Sandrine Bourgeois, Cyril Pailler-Mattei, Géraldine Agusti, Stéphanie Briançon and Hatem Fessi

      Version of Record online: 27 SEP 2016 | DOI: 10.1111/jphp.12627

    4. You have full text access to this OnlineOpen article
      How to optimise drug study design: pharmacokinetics and pharmacodynamics studies introduced to paediatricians

      Eric Vermeulen, John N. van den Anker, Oscar Della Pasqua, Kalle Hoppu, Johanna H. van der Lee and On behalf of Global Research in Paediatrics (GRiP)

      Version of Record online: 27 SEP 2016 | DOI: 10.1111/jphp.12637

    5. Ocular topotecan pharmacokinetics following topical administration to rabbits for diffused anterior retinoblastoma

      Paula Taich, Maria Del Sole, Fabian Buontempo, Gustavo Williams, Ursula Winter, Mariana Sgroi, Guillermo Chantada and Paula Schaiquevich

      Version of Record online: 30 AUG 2016 | DOI: 10.1111/jphp.12624

  16. Reviews

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      Pharmacological sedation management in the paediatric intensive care unit

      Manuel A. Baarslag, Karel Allegaert, Catherijne A.J. Knibbe, Monique van Dijk and Dick Tibboel

      Version of Record online: 21 AUG 2016 | DOI: 10.1111/jphp.12630

  17. Research Papers

    1. Low-volume solubility assessment during high-concentration protein formulation development

      Melanie Hofmann, Matthias Winzer, Christian Weber and Henning Gieseler

      Version of Record online: 21 AUG 2016 | DOI: 10.1111/jphp.12621

  18. Reviews

    1. You have full text access to this OnlineOpen article
      Evidence of acceptability of oral paediatric medicines: a review

      Punam Mistry and Hannah Batchelor, on behalf of SPaeDD-UK project (Smart Paediatric Drug Development – UK)

      Version of Record online: 14 AUG 2016 | DOI: 10.1111/jphp.12610

  19. Research Papers

    1. Standard concentration infusions in paediatric intensive care: the clinical approach

      Joanne Perkins, Virginia Aguado-Lorenzo and Sara Arenas-Lopez

      Version of Record online: 14 AUG 2016 | DOI: 10.1111/jphp.12604

    2. Production and characterization of spray-dried theophylline powders prepared from fresh milk for potential use in paediatrics

      João P. Aguiar, Tânia A. P. Fernandes, Carlotta Nese, Ana I. Fernandes and João F. Pinto

      Version of Record online: 3 AUG 2016 | DOI: 10.1111/jphp.12612

    3. Relative bioavailability of coenzyme Q10 formulation for paediatric individualized therapy

      Manuela Martinefski, Paula Samassa, Fabian Buontempo, Christian Höcht, Silvia Lucangioli and Valeria Tripodi

      Version of Record online: 27 JUL 2016 | DOI: 10.1111/jphp.12613

    4. Novel carvedilol paediatric nanomicelle formulation: in-vitro characterization and in-vivo evaluation

      Marcel Wegmann, Luciano Parola, Facundo M. Bertera, Carlos A. Taira, Maximiliano Cagel, Fabian Buontempo, Ezequiel Bernabeu, Christian Höcht, Diego A. Chiappetta and Marcela A. Moretton

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/jphp.12605

    5. Influence of particle shedding from silicone tubing on antibody stability

      Verena Saller, Constanze Hediger, Julia Matilainen, Ulla Grauschopf, Karoline Bechtold-Peters, Hanns-Christian Mahler and Wolfgang Friess

      Version of Record online: 1 JUL 2016 | DOI: 10.1111/jphp.12603

  20. Reviews

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      Clinical pharmacology of analgosedatives in neonates: ways to improve their safe and effective use

      Anne Smits, John N. van den Anker and Karel Allegaert

      Version of Record online: 30 JUN 2016 | DOI: 10.1111/jphp.12599

  21. Research Papers

    1. The Milky Way: paediatric milk-based dispersible tablets prepared by direct compression – a proof-of-concept study

      Samuel E. F. Orubu, Nicholas J. Hobson, Abdul W. Basit and Catherine Tuleu

      Version of Record online: 28 JUN 2016 | DOI: 10.1111/jphp.12570

    2. You have full text access to this OnlineOpen article
      Off-label and unlicensed medicines to hospitalised children in Norway

      Arna Teigen, Siri Wang, Bich Thuy Truong and Kathrin Bjerknes

      Version of Record online: 23 JUN 2016 | DOI: 10.1111/jphp.12581

    3. Safe implementation of standard concentration infusions in paediatric intensive care

      Sara Arenas-López, Isabel M. Stanley, Paul Tunstell, Virginia Aguado-Lorenzo, Jo Philip, Joanne Perkins, Andrew Durward, Miguel Angel Calleja-Hernández and Shane M. Tibby

      Version of Record online: 23 JUN 2016 | DOI: 10.1111/jphp.12580

    4. Deferasirox pharmacokinetic evaluation in β-thalassaemia paediatric patients

      Sarah Allegra, Jessica Cusato, Silvia De Francia, Elisa Pirro, Davide Massano, Antonio Piga and Antonio D'Avolio

      Version of Record online: 27 MAY 2016 | DOI: 10.1111/jphp.12559

    5. You have full text access to this OnlineOpen article
      Standardized method to assess medicines’ acceptability: focus on paediatric population

      Fabrice Ruiz, Thibault Vallet, Anne-Marie Pensé-Lhéritier and Ameziane Aoussat

      Version of Record online: 25 APR 2016 | DOI: 10.1111/jphp.12547

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