Journal of Pharmacy and Pharmacology

Cover image for Vol. 69 Issue 4

Early View (Online Version of Record published before inclusion in an issue)

Edited By: D Jones, Queen's University of Belfast, UK

Impact Factor: 2.363

ISI Journal Citation Reports © Ranking: 2015: 127/255 (Pharmacology & Pharmacy)

Online ISSN: 2042-7158


  1. 1 - 40
  1. Research Papers

    1. The antiproliferative and apoptotic effects of apigenin on glioblastoma cells

      Trevor A. Stump, Brittany N. Santee, Lauren P. Williams, Rachel A. Kunze, Chelsae E. Heinze, Eric D. Huseman, Rebecca J. Gryka, Denise S. Simpson and Samson Amos

      Version of Record online: 28 MAR 2017 | DOI: 10.1111/jphp.12718

    2. Antihyperglycaemic activity of the methanol extract from leaves of Eremophila maculata (Scrophulariaceae) in streptozotocin-induced diabetic rats

      Fadia S. Youssef, Mohamed L. Ashour, Sherif S. Ebada, Mansour Sobeh, Hesham A. El-Beshbishy, Abdel Nasser Singab and Michael Wink

      Version of Record online: 21 MAR 2017 | DOI: 10.1111/jphp.12690

    3. The formation of a host-guest inclusion complex system between β-cyclodextrin and baicalin and its dissolution characteristics

      Jing Li, Qihua Jiang, Ping Deng, Qian Chen, Mingan Yu, Jingchuan Shang and Wei Li

      Version of Record online: 16 MAR 2017 | DOI: 10.1111/jphp.12708

    4. Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes

      Xinghui Wang, Qiong Wang, Zhihui Liu and Xiao Zheng

      Version of Record online: 15 MAR 2017 | DOI: 10.1111/jphp.12692

    5. Permeation characteristics of hypericin across Caco-2 monolayers in the presence of single flavonoids, defined flavonoid mixtures or Hypericum extract matrix

      Sheela Verjee, Olaf Kelber, Christiane Kolb, Heba Abdel-Aziz and Veronika Butterweck

      Version of Record online: 12 MAR 2017 | DOI: 10.1111/jphp.12717

    6. Inhibition of pro-inflammatory mediators in RAW264.7 cells by 7-hydroxyflavone and 7,8-dihydroxyflavone

      Zhen Jin, Yao-Zhi Yang, Jian-Xin Chen and You-Zhi Tang

      Version of Record online: 10 MAR 2017 | DOI: 10.1111/jphp.12714

  2. Reviews

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      Statins anticancer targeted delivery systems: re-purposing an old molecule

      Sally Safwat, Rania A. Ishak, Rania M. Hathout and Nahed D. Mortada

      Version of Record online: 8 MAR 2017 | DOI: 10.1111/jphp.12707

  3. Research Papers

    1. Trigonelline and vildagliptin antidiabetic effect: improvement of insulin signalling pathway

      Amat-Alrazaq A. Aldakinah, Muhammad Y. Al-Shorbagy, Dalaal M. Abdallah and Hanan S. El-Abhar

      Version of Record online: 8 MAR 2017 | DOI: 10.1111/jphp.12713

    2. Characterization of anti-inflammatory effect and possible mechanism of action of Tibouchina granulosa

      Andrea P. Sobrinho, Alan S. Minho, Leide L.C. Ferreira, Gabriel R. Martins, Fabio Boylan and Patricia D. Fernandes

      Version of Record online: 8 MAR 2017 | DOI: 10.1111/jphp.12712

  4. Reviews

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      Personalised dosing of medicines for children

      Basma Al-Metwali and Hussain Mulla

      Version of Record online: 7 MAR 2017 | DOI: 10.1111/jphp.12709

    2. You have free access to this content
      Quality control of Hypericum perforatum L. analytical challenges and recent progress

      Anastasia Agapouda, Anthony Booker, Tivadar Kiss, Judit Hohmann, Michael Heinrich and Dezső Csupor

      Version of Record online: 7 MAR 2017 | DOI: 10.1111/jphp.12711

  5. Research Papers

    1. Astragaloside II sensitizes human hepatocellular carcinoma cells to 5-fluorouracil via suppression of autophagy

      Meng Wang, Can Huang, Yong Su, Cui Yang, Quan Xia and Du-juan Xu

      Version of Record online: 7 MAR 2017 | DOI: 10.1111/jphp.12706

  6. Reviews

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  7. Research Papers

    1. Decorin-loaded poly lactic-co-glycolic acid nanoparticles modified by anti-alpha fetoprotein antibody: preparation, proliferation inhibition and induced apoptosis effects on HepG2 cells in vitro

      Qiaoli Yang, Shuyue Wang, Yuan Wang, Yane Qu, Jun Xue, Yang Mi, Yanhong Wang, Xuguang Luo, Zhihua Deng and Guiqin Wang

      Version of Record online: 7 MAR 2017 | DOI: 10.1111/jphp.12695

    2. Influence of hyperglycemia on liver inflammatory conditions in the early phase of non-alcoholic fatty liver disease in mice

      Shinichi Harada, Kei Miyagi, Tokio Obata, Yasuko Morimoto, Kazuo Nakamoto, Ke Ih Kim, Soo Ki Kim, Soo Ryang Kim and Shogo Tokuyama

      Version of Record online: 21 FEB 2017 | DOI: 10.1111/jphp.12705

    3. Pharmacokinetics and pharmacodynamics of metamizol in co-administration with morphine under acute and chronic treatments in arthritic rats

      Patricia Esmeralda Carrillo-Calzadilla, Francisco Javier López-Muñoz, Luis Alfonso Moreno-Rocha, José Raúl Medina-López, Alma Rosa Cortés-Arroyo and Adriana Miriam Domínguez-Ramírez

      Version of Record online: 21 FEB 2017 | DOI: 10.1111/jphp.12702

    4. Complexation of oxethazaine with 2-hydroxypropyl-β-cyclodextrin: increased drug solubility, decreased cytotoxicity and analgesia at inflamed tissues

      Andressa R. Prado, Fabiano Yokaichiya, Margareth Kazuyo Kobayashi Dias Franco, Camila Morais Gonçalves da Silva, Laura Oliveira-Nascimento, Michelle Franz-Montan, Maria C. Volpato, Luís F. Cabeça and Eneida de Paula

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12703

    5. You have full text access to this OnlineOpen article
      Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux

      Anna Subbotina, Aina W. Ravna, Roy A. Lysaa, Ruben Abagyan, Ryszard Bugno and Georg Sager

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12693

    6. Cytotoxic analysis and chemical characterization of fractions of the hydroalcoholic extract of the Euterpe oleracea Mart. seed in the MCF-7 cell line

      Dayanne da S. Freitas, José A. Morgado-Díaz, Adriana S. Gehren, Flávia C. B. Vidal, Raquel Maria T. Fernandes, Wanderson Romão, Lilian V. Tose, Fabiola N. S. Frazão, Maria Célia P. Costa, Dulcelena F. Silva and Maria do Desterro S. B. Nascimento

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12679

    7. Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness

      Carlos T. M. Moura, Francisco J. Batista-Lima, Teresinha S. Brito, Alfredo A. V. Silva, Luan C. Ferreira, Cássia R. Roque, Karoline S. Aragão, Alexandre Havt, Francisco N. Fonseca, Luzia K. A. M. Leal and Pedro J. C. Magalhães

      Version of Record online: 17 FEB 2017 | DOI: 10.1111/jphp.12689

  8. Reviews

    1. You have free access to this content
      Biopharmaceutical Informatics: supporting biologic drug development via molecular modelling and informatics

      Sandeep Kumar, Nikolay V. Plotnikov, Jason C. Rouse and Satish K. Singh

      Version of Record online: 3 FEB 2017 | DOI: 10.1111/jphp.12700

    2. You have free access to this content
  9. Research Papers

    1. Limitations of polyethylene glycol-induced precipitation as predictive tool for protein solubility during formulation development

      Melanie Hofmann, Matthias Winzer, Christian Weber and Henning Gieseler

      Version of Record online: 20 JAN 2017 | DOI: 10.1111/jphp.12699

    2. Accuracy of tablet splitting and liquid measurements: an examination of who, what and how

      Dana Abu-Geras, Dunja Hadziomerovic, Andrew Leau, Ramzan Nazim Khan, Sajni Gudka, Cornelia Locher, Maryam Razaghikashani and Lee Yong Lim

      Version of Record online: 28 DEC 2016 | DOI: 10.1111/jphp.12671

  10. Reviews

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      Effects of localized interactions and surface properties on stability of protein-based therapeutics

      Brittney J. Mills and Jennifer S. Laurence Chadwick

      Version of Record online: 10 NOV 2016 | DOI: 10.1111/jphp.12658

  11. Research Papers

    1. Challenge of paediatric compounding to solid dosage forms sachets and hard capsules – Finnish perspective

      Mia Sivén, Satu Kovanen, Outi Siirola, Tuomas Hepojoki, Sari Isokirmo, Niina Laihanen, Tiina Eränen, Jukka Pellinen and Anne M. Juppo

      Version of Record online: 5 OCT 2016 | DOI: 10.1111/jphp.12648

    2. Microparticle surface layering through dry coating: impact of moisture content and process parameters on the properties of orally disintegrating tablets

      Hamad Alyami, Jasdip Koner, Eman Z. Dahmash, James Bowen, David Terry and Afzal R. Mohammed

      Version of Record online: 2 OCT 2016 | DOI: 10.1111/jphp.12623

    3. Formulation of orodispersible films for paediatric therapy: investigation of feasibility and stability for tetrabenazine as drug model

      Zoé Senta-Loys, Sandrine Bourgeois, Cyril Pailler-Mattei, Géraldine Agusti, Stéphanie Briançon and Hatem Fessi

      Version of Record online: 27 SEP 2016 | DOI: 10.1111/jphp.12627

    4. Ocular topotecan pharmacokinetics following topical administration to rabbits for diffused anterior retinoblastoma

      Paula Taich, Maria Del Sole, Fabian Buontempo, Gustavo Williams, Ursula Winter, Mariana Sgroi, Guillermo Chantada and Paula Schaiquevich

      Version of Record online: 30 AUG 2016 | DOI: 10.1111/jphp.12624

  12. Reviews

    1. You have free access to this content
      Pharmacological sedation management in the paediatric intensive care unit

      Manuel A. Baarslag, Karel Allegaert, Catherijne A.J. Knibbe, Monique van Dijk and Dick Tibboel

      Version of Record online: 21 AUG 2016 | DOI: 10.1111/jphp.12630

  13. Research Papers

    1. Low-volume solubility assessment during high-concentration protein formulation development

      Melanie Hofmann, Matthias Winzer, Christian Weber and Henning Gieseler

      Version of Record online: 21 AUG 2016 | DOI: 10.1111/jphp.12621

    2. Standard concentration infusions in paediatric intensive care: the clinical approach

      Joanne Perkins, Virginia Aguado-Lorenzo and Sara Arenas-Lopez

      Version of Record online: 14 AUG 2016 | DOI: 10.1111/jphp.12604

    3. Production and characterization of spray-dried theophylline powders prepared from fresh milk for potential use in paediatrics

      João P. Aguiar, Tânia A. P. Fernandes, Carlotta Nese, Ana I. Fernandes and João F. Pinto

      Version of Record online: 3 AUG 2016 | DOI: 10.1111/jphp.12612

    4. Relative bioavailability of coenzyme Q10 formulation for paediatric individualized therapy

      Manuela Martinefski, Paula Samassa, Fabian Buontempo, Christian Höcht, Silvia Lucangioli and Valeria Tripodi

      Version of Record online: 27 JUL 2016 | DOI: 10.1111/jphp.12613

    5. Novel carvedilol paediatric nanomicelle formulation: in-vitro characterization and in-vivo evaluation

      Marcel Wegmann, Luciano Parola, Facundo M. Bertera, Carlos A. Taira, Maximiliano Cagel, Fabian Buontempo, Ezequiel Bernabeu, Christian Höcht, Diego A. Chiappetta and Marcela A. Moretton

      Version of Record online: 19 JUL 2016 | DOI: 10.1111/jphp.12605

    6. Influence of particle shedding from silicone tubing on antibody stability

      Verena Saller, Constanze Hediger, Julia Matilainen, Ulla Grauschopf, Karoline Bechtold-Peters, Hanns-Christian Mahler and Wolfgang Friess

      Version of Record online: 1 JUL 2016 | DOI: 10.1111/jphp.12603

    7. Safe implementation of standard concentration infusions in paediatric intensive care

      Sara Arenas-López, Isabel M. Stanley, Paul Tunstell, Virginia Aguado-Lorenzo, Jo Philip, Joanne Perkins, Andrew Durward, Miguel Angel Calleja-Hernández and Shane M. Tibby

      Version of Record online: 23 JUN 2016 | DOI: 10.1111/jphp.12580

    8. Deferasirox pharmacokinetic evaluation in β-thalassaemia paediatric patients

      Sarah Allegra, Jessica Cusato, Silvia De Francia, Elisa Pirro, Davide Massano, Antonio Piga and Antonio D'Avolio

      Version of Record online: 27 MAY 2016 | DOI: 10.1111/jphp.12559


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