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Sperm chromatin structure assay in prediction of in vitro fertilization outcome
ANDROLOGY Volume 4, Issue 2, Pages 290–296, March 2016. K. Oleszczuk*, A. Giwercman andM. Bungum
Sperm DNA fragmentation index (DFI) assessed by sperm chromatin structure assay is a valuable tool for prediction of fertility in vivo. Previous studies on DFI as predictor of in vitro fertilization (IVF) outcome, based on relatively small materials, gave contradictory results.The authors of this study found that ICSI might be a preferred method of in vitro treatment in cases with high DFI, and efforts should be made to find options for pharmacologically induced reduction of DFI.
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