Lithium Dichloro(1-methylethyl)-magnesate

Paul Knochel, Ludwig-Maximilians Universität, Munich, Germany
Andrei Gavryushin, Ludwig-Maximilians Universität, Munich, Germany


[807329-97-1]     C3H7Cl2LiMg     (MW 145.24)

InChI = 1S/C3H7.2ClH.Li.Mg/c1-3-2;;;;/h3H,1-2H3;2*1H;;/q;;;2*+1/p-2


(reagent used in preparation of various organomagnesium compounds via halogen–magnesium exchange reactions)

Alternate Name:  isopropylmagnesium chloride–lithium chloride complex.

Physical Data:  solution in THF, similar to the solvent.

Solubility:  solution in THF miscible with the majority of organic solvents. The neat compound is insoluble in alkanes and soluble in coordinating solvents (ethers, amines, etc.)

Form Supplied in:  THF solution (1.1–1.3 M).

Purification:  not considered.

Handling, Storage, and Precautions:  the solution of the reagent rapidly reacts with oxygen and water and should be stored and handled in an inert atmosphere. Vigorously reacts with water and aqueous solutions, evolving highly flammable gases. Due to its strong dehydrating ability, spills may cause serious damage to the skin and eyes. The commercial solution in THF is a flammable liquid.