Research Highlights

Research Highlights

American Journal of Medical Genetics: Part A
Elements of morphology: Standard terminology for the head and face
Judith E. Allanson, Christopher Cunniff, H. Eugene Hoyme, Julie McGaughran, Max Muenke, Giovanni Neri

Etiology of nonimmune hydrops fetalis: A systematic review
Carlo Bellini, Raoul C.M. Hennekam, Ezio Fulcheri, Mariangela Rutigliani, Guido Morcaldi, Francesco Boccardo, Eugenio Bonioli

Hedgehog signaling update
M. Michael Cohen Jr

Annals of Human Genetics
Using Biological Knowledge to Uncover the Mystery in the Search for Epistasis in Genome-Wide Association Studies
Marylyn D. Ritchie

Y-chromosomal Binary Haplogroups in the Japanese Population and their Relationship to 16 Y-STR Polymorphisms
I. Nonaka, K. Minaguchi, N. Takezaki

Genome-Wide Association Scan Allowing for Epistasis in Type 2 Diabetes
Jordana T. Bell, Nicholas J. Timpson, N. William Rayner, Eleftheria Zeggini, Timothy M. Frayling, Andrew T. Hattersley, Andrew P. Morris, Mark I. McCarthy

Clinical Genetics
Whole-exome sequencing: a powerful technique for identifying novel genes of complex disorders
SS Sanders

Preimplantation genetic diagnosis
JPM Geraedts, GMWR De Wert

Gene copy number variation and common human disease
M Fanciulli, E Petretto, TJ Aitman

Genes to Cells
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution
Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto

Activating mutations of TOR (target of rapamycin)
Molly Hardt, Naphat Chantaravisoot, Fuyuhiko Tamanoi

Lectin microarray analysis of pluripotent and multipotent stem cells
Masashi Toyoda, Mayu Yamazaki-Inoue, Yoko Itakura, Atsushi Kuno, Tomohisa Ogawa, Masao Yamada, Hidenori Akutsu, Yuji Takahashi, Seiichi Kanzaki, Hisashi Narimatsu, Jun Hirabayashi, Akihiro Umezawa

The Journal of Gene Medicine
Gene therapy clinical trials worldwide to 2007—an update
Michael L. Edelstein, Mohammad R. Abedi, Jo Wixon

Optimized production and concentration of lentiviral vectors containing large inserts
Nadya al Yacoub, Malgorzata Romanowska, Natalie Haritonova, John Foerster

Gene therapy strategies for hemophilia: benefits versus risks
Inge Petrus, Marinee Chuah, Thierry VandenDriessche

Aging Cell
Progressive loss of SIRT1 with cell cycle withdrawal
Tsutomu Sasaki, Bernhard Maier, Andrzej Bartke, Heidi Scrable

Aging and disease: connections to sirtuins
Gizem Donmez, Leonard Guarente

Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans
Laurent Mouchiroud, Laurent Molin, Prasad Kasturi, Mohamed N. Triba, Marc Emmanuel Dumas, Marieangela C. Wilson, Andrew P. Halestrap, Damien Roussel, Ingrid Masse, Nicolas Dallière, Laurent Ségalat, Marc Billaud, Florence Solari