This article was published online on 25 March 2015. An error was subsequently identified. This notice is included in the online version to indicate that it has been corrected on 8 April 2015.
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Bridging Systems Medicine and Patient Needs
Version of Record online: 27 MAR 2015
DOI: 10.1002/psp4.26
© 2015 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics.
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
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How to Cite
Boissel, J.-P., Auffray, C., Noble, D., Hood, L. and Boissel, F.-H. (2015), Bridging Systems Medicine and Patient Needs. CPT: Pharmacometrics & Systems Pharmacology, 4: 135–145. doi: 10.1002/psp4.26
Publication History
- Issue online: 4 MAR 2015
- Version of Record online: 27 MAR 2015
- Manuscript Accepted: 5 FEB 2015
- Manuscript Received: 24 NOV 2014
Funded by
- SysCLAD Consortium. Grant Number: 305457
- Abstract
- Article
- References
- Cited By
While there is widespread consensus on the need both to change the prevailing research and development (R&D) paradigm and provide the community with an efficient way to personalize medicine, ecosystem stakeholders grapple with divergent conceptions about which quantitative approach should be preferred. The primary purpose of this position paper is to contrast these approaches. The second objective is to introduce a framework to bridge simulation outputs and patient outcomes, thus empowering the implementation of systems medicine.
