Ultrasmall NaGdF4 Nanodots for Efficient MR Angiography and Atherosclerotic Plaque Imaging
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorCorresponding Author
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
E‐mail: wbbu@mail.sic.ac.cn, jlshi@mail.sic.ac.cnSearch for more papers by this authorDepartment of radiation oncology, Shanghai Huadong Hospital, Fudan University, Shanghai, 200040 P.R. China
Search for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorShanghai (Red Cross) Blood Center, Shanghai Institute of Blood Transfusion, Shanghai, 200051 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorDepartment of radiation oncology, Shanghai Huadong Hospital, Fudan University, Shanghai, 200040 P.R. China
Search for more papers by this authorCorresponding Author
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
E‐mail: wbbu@mail.sic.ac.cn, jlshi@mail.sic.ac.cnSearch for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorCorresponding Author
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
E‐mail: wbbu@mail.sic.ac.cn, jlshi@mail.sic.ac.cnSearch for more papers by this authorDepartment of radiation oncology, Shanghai Huadong Hospital, Fudan University, Shanghai, 200040 P.R. China
Search for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
Search for more papers by this authorShanghai (Red Cross) Blood Center, Shanghai Institute of Blood Transfusion, Shanghai, 200051 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorDepartment of radiology, Shanghai Cancer Hospital, Fudan University, Shanghai, 200032 P.R. China
Search for more papers by this authorDepartment of radiation oncology, Shanghai Huadong Hospital, Fudan University, Shanghai, 200040 P.R. China
Search for more papers by this authorCorresponding Author
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics Chinese Academy of Sciences, Shanghai, 200050 P.R. China
E‐mail: wbbu@mail.sic.ac.cn, jlshi@mail.sic.ac.cnSearch for more papers by this authorAbstract
Herein, ultrasmall NaGdF4 nanodots (~2 nm) with DTPA conjugation have been synthesized for efficient MR angiography. Impressively, the r1 value in MRI reaches up to 8.93 mM−1·s−1. The ultrasmall vessel lumen of a rabbit is lighted up remarkably. After 3 h, atherosclerotic plaques could be discriminated clearly. This is beneficial for the accurate early diagnosis of vascular pathema.
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