Communication

Injectable Smart Phase‐Transformation Implants for Highly Efficient In Vivo Magnetic‐Hyperthermia Regression of Tumors

State Key Laboratory of High Performance Ceramics and Superfine microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 200050 Shanghai, P. R. China

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Ling Jiang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Ronghui Wang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Ming Lu

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Qunxia Zhang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Yang Zhou

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Zhigang Wang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Guangming Lu

Corresponding Author

Nanjing General Hospital of Nanjing Military Command, 210002 Nanjing, P. R. China

E‐mail: zhengyuanyi@gmail.com, hrchen@mail.sic.ac.cn, cjr.luguangming@vip.163.com Search for more papers by this author

Ping Liang

The General Hospital of Chinese People's Liberation Army, 100853 Beijing, P.R. China

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Haitao Ran

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Hangrong Chen

Corresponding Author

State Key Laboratory of High Performance Ceramics and Superfine microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 200050 Shanghai, P. R. China

E‐mail: zhengyuanyi@gmail.com, hrchen@mail.sic.ac.cn, cjr.luguangming@vip.163.com Search for more papers by this author

Yuanyi Zheng

Corresponding Author

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

E‐mail: zhengyuanyi@gmail.com, hrchen@mail.sic.ac.cn, cjr.luguangming@vip.163.com Search for more papers by this author

Yu Chen

State Key Laboratory of High Performance Ceramics and Superfine microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 200050 Shanghai, P. R. China

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Ling Jiang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Ronghui Wang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Ming Lu

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Qunxia Zhang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Yang Zhou

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Zhigang Wang

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Guangming Lu

Corresponding Author

Nanjing General Hospital of Nanjing Military Command, 210002 Nanjing, P. R. China

E‐mail: zhengyuanyi@gmail.com, hrchen@mail.sic.ac.cn, cjr.luguangming@vip.163.com Search for more papers by this author

Ping Liang

The General Hospital of Chinese People's Liberation Army, 100853 Beijing, P.R. China

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Haitao Ran

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

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Hangrong Chen

Corresponding Author

State Key Laboratory of High Performance Ceramics and Superfine microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 200050 Shanghai, P. R. China

E‐mail: zhengyuanyi@gmail.com, hrchen@mail.sic.ac.cn, cjr.luguangming@vip.163.com Search for more papers by this author

Yuanyi Zheng

Corresponding Author

Second Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, P. R. China

E‐mail: zhengyuanyi@gmail.com, hrchen@mail.sic.ac.cn, cjr.luguangming@vip.163.com Search for more papers by this author

First published: 28 August 2014

https://doi.org/10.1002/adma.201402509

Citations: 43

Abstract

A minimally invasive, highly efficient and versatile strategy is proposed for localized tumor regression by developing a smart injectable liquid–solid phase‐transformation organic–inorganic hybrid composite material, i.e., magnetic‐Fe‐powder‐dispersed PLGA (Fe/PLGA) implants for magnetic hyperthermia therapy of cancer.