Bio‐Nanostructures: Protein Bricks: 2D and 3D Bio‐Nanostructures with Shape and Function on Demand (Adv. Mater. 20/2018)
State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
Search for more papers by this authorDepartment of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712 USA
Search for more papers by this authorState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
Search for more papers by this authorState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049 China
Search for more papers by this authorDepartment of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040 China
Search for more papers by this authorDepartment of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
School of Physical Science and Technology, Shanghai Tech University, Shanghai, 200031 China
Search for more papers by this authorDepartment of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040 China
Search for more papers by this authorDepartment of Biomedical Engineering, Tufts University, Medford, MA, 02155 USA
Search for more papers by this authorDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794 USA
Search for more papers by this authorDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794 USA
Search for more papers by this authorDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794 USA
Search for more papers by this authorDepartment of Biomedical Engineering, Tufts University, Medford, MA, 02155 USA
Search for more papers by this authorState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712 USA
School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049 China
School of Physical Science and Technology, Shanghai Tech University, Shanghai, 200031 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
Search for more papers by this authorDepartment of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712 USA
Search for more papers by this authorState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
Search for more papers by this authorState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049 China
Search for more papers by this authorDepartment of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040 China
Search for more papers by this authorDepartment of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
School of Physical Science and Technology, Shanghai Tech University, Shanghai, 200031 China
Search for more papers by this authorDepartment of Neurosurgery, Huashan Hospital of Fudan University, Wulumuqi Zhong Road 12, Shanghai, 200040 China
Search for more papers by this authorDepartment of Biomedical Engineering, Tufts University, Medford, MA, 02155 USA
Search for more papers by this authorDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794 USA
Search for more papers by this authorDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794 USA
Search for more papers by this authorDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11794 USA
Search for more papers by this authorDepartment of Biomedical Engineering, Tufts University, Medford, MA, 02155 USA
Search for more papers by this authorState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240 China
Search for more papers by this authorState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050 China
Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712 USA
School of Graduate Study, University of Chinese Academy of Sciences, Beijing, 100049 China
School of Physical Science and Technology, Shanghai Tech University, Shanghai, 200031 China
Search for more papers by this authorAbstract
A class of well‐defined, complex protein‐based 2D and 3D nanostructures with shape and function on demand is manufactured and assembled via “Protein Bricks” by precisely patterning on genetically engineered spider silk using ion and electron beams, as reported by Xiaoxia Xia, Tiger H. Tao, and co‐workers in article number 1705919. This approach provides a facile method for excellent biocompatibility, ease of functionalization, heterogeneous nanostructuring, and controllable 3D assembly, shedding light on a wide range of applications such as biosensing for structure enhanced fluorescence and biomimetic microenvironments for controlling cell fate.





