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Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

Chris H. Polman MD, PhD

Corresponding Author

E-mail address: ch.polman@vumc.nl

Department of Neurology, Free University, Amsterdam, the Netherlands

Department of Neurology, VU Medical Center Amsterdam, PO Box 7057, 1007 MB Amsterdam, the Netherlands
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Stephen C. Reingold PhD

Scientific and Clinical Review Associates LLC, New York, NY

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Brenda Banwell MD

Division of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada

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Michel Clanet MD

Department of Neurosciences, University Hospital Center, Toulouse, France

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Jeffrey A. Cohen MD

Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinical Foundation, Cleveland, OH

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Massimo Filippi MD

Neuroimaging Research Unit, Division of Neuroscience, Scientific Institute and University Hospital San Raffaele, Milan, Italy

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Kazuo Fujihara MD

Department of Multiple Sclerosis Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Japan

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Eva Havrdova MD, PhD

Department of Neurology, First Faculty of Medicine, Charles University, Prague, Czech Republic

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Michael Hutchinson MD

St Vincent's University Hospital, Elm Park, Dublin, Ireland

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Ludwig Kappos MD

Departments of Neurology and Biomedicine, University Hospital, Kantonsspital, Basel, Switzerland

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Fred D. Lublin MD

Corrine Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Mount Sinai School of Medicine, New York, NY

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Xavier Montalban MD

Clinical Neuroimmunology Unit, Multiple Sclerosis Center of Catalonia, University Hospital Vall d'Hebron, Barcelona, Spain

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Paul O'Connor MD

Division of Neurology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

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Magnhild Sandberg‐Wollheim MD, PhD

Department of Neurology, University Hospital, Lund, Sweden

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Alan J. Thompson MD

University College London Institute of Neurology, United Kingdom

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Emmanuelle Waubant MD, PhD

Multiple Sclerosis Center, University of California, San Francisco, CA

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Brian Weinshenker MD

Department of Neurology, Mayo Clinic, Rochester, MN

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Jerry S. Wolinsky MD

Department of Neurology, University of Texas Health Sciences Center, Houston, TX

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First published: 11 January 2011
Cited by: 3590

Abstract

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnostic sensitivity and specificity, address their applicability across populations, and may allow earlier diagnosis and more uniform and widespread use. Ann Neurol 2011

Number of times cited according to CrossRef: 3590

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  • SPIE Medical Imaging Orlando, Florida, United States Saturday 21 February 2015 SPIE Proceedings 0277786X Medical Imaging 2015: Image Processing 9413 SPIE , (2015). Multi-output decision trees for lesion segmentation in multiple sclerosis , (2015). 94131C , 10.1117/12.2082157 http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2082157 SPIE Medical Imaging Orlando, Florida, United States Saturday 21 February 2015 SPIE Proceedings 0277786X Medical Imaging 2015: Image Processing 9413 SPIE , (2015). Locally adaptive MR intensity models and MRF-based segmentation of multiple sclerosis lesions , (2015). 94133G , 10.1117/12.2081642 http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2081642
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