The full text of this article hosted at iucr.org is unavailable due to technical difficulties.

Communication

Tip‐Enhanced Raman Spectroscopy of Single RNA Strands: Towards a Novel Direct‐Sequencing Method

Elena Bailo

E-mail address:bailo@isas.de

ISAS—Institute for Analytical Sciences, Bunsen‐Kirchhoff‐Strasse 11, 44139 Dortmund, Germany, Fax: (+49) 231–1392–120 http://www.isas.de

Search for more papers by this author
Volker Deckert Dr.

E-mail address:deckert@isas.de

ISAS—Institute for Analytical Sciences, Bunsen‐Kirchhoff‐Strasse 11, 44139 Dortmund, Germany, Fax: (+49) 231–1392–120 http://www.isas.de

Search for more papers by this author
First published: 11 February 2008
Cited by: 190

Abstract

Walking the strand: Tip‐enhanced Raman scattering (TERS) with precision probe positioning has been used to obtain high‐quality Raman spectra of the nucleobases in a single RNA strand (see picture: foreground Raman spectrum, background atomic‐force microscope tip positioned over the RNA strand). This procedure represents the first step towards direct and label‐free single‐biomolecule sequencing.

Number of times cited: 190

  • , High‐Throughput Block Optical DNA Sequence Identification, Small, 14, 4, (2017).
  • , Probe microscopy methods and applications in imaging of biological materials, Seminars in Cell & Developmental Biology, 10.1016/j.semcdb.2017.08.018, 73, (153-164), (2018).
  • , Propagating surface plasmon polaritons for remote excitation surface-enhanced Raman scattering spectroscopy, Applied Spectroscopy Reviews, (1), (2018).
  • , Nanoscale investigation of materials, chemical reactions, and biological systems by tip enhanced Raman spectroscopy – a review, Journal of Materials Chemistry C, 6, 6, (1307), (2018).
  • , Review: Tip-based vibrational spectroscopy for nanoscale analysis of emerging energy materials, Frontiers in Energy, 10.1007/s11708-018-0524-8, 12, 1, (43-71), (2018).
  • , Tip‐Enhanced Raman Spectroscopy: A Tool for Nanoscale Chemical and Structural Characterization of Biomolecules, ChemPhysChem, 19, 1, (8-18), (2017).
  • , Distinguishing Individual DNA Bases in a Network by Non‐Resonant Tip‐Enhanced Raman Scattering, Angewandte Chemie International Edition, 56, 20, (5561-5564), (2017).
  • , Hybrid AFM for Nanoscale Physicochemical Characterization: Recent Development and Emerging Applications, Small, 13, 11, (2017).
  • , Tip in–light on: Advantages, challenges, and applications of combining AFM and Raman microscopy on biological samples, Microscopy Research and Technique, 80, 1, (30-40), (2016).
  • , Two-photon luminescence contrast by tip-sample coupling in femtosecond near-field optical microscopy, Applied Physics B, 123, 1, (2017).
  • , Mastering high resolution tip-enhanced Raman spectroscopy: towards a shift of perception, Chemical Society Reviews, 46, 13, (3922), (2017).
  • , Near-Field Raman Enhancement of Single Molecules and Point Scatterers, The Journal of Physical Chemistry C, 121, 34, (18800), (2017).
  • , Tunable, Liquid Resistant Tip Enhanced Raman Spectroscopy Probes: Toward Label-Free Nano-Resolved Imaging of Biological Systems, Langmuir, 10.1021/acs.langmuir.7b01338, 33, 31, (7818-7825), (2017).
  • , Single-Molecule Chemistry with Surface- and Tip-Enhanced Raman Spectroscopy, Chemical Reviews, 117, 11, (7583), (2017).
  • , Perspectives for Future DNA Sequencing Techniques and Applications, Molecular Diagnostics, 10.1016/B978-0-12-802971-8.00008-0, (141-153), (2017).
  • , STM tip-enhanced Raman spectroscopy and the investigation of doped graphene, Vibrational Spectroscopy, 91, (128), (2017).
  • , Raman spectroscopy: techniques and applications in the life sciences, Advances in Optics and Photonics, 10.1364/AOP.9.000315, 9, 2, (315), (2017).
  • , Nano-Raman Scattering Microscopy: Resolution and Enhancement, Chemical Reviews, 10.1021/acs.chemrev.6b00560, 117, 7, (4983-5001), (2017).
  • , Apertureless near-field optical microscopy, Uspekhi Fizicheskih Nauk, 10.3367/UFNr.2016.05.037817, 187, 03, (277-295), (2016).
  • , Tip-enhanced Raman spectroscopy – from early developments to recent advances, Chemical Society Reviews, 10.1039/C7CS00209B, 46, 13, (4077-4110), (2017).
  • , In-line interferometer for broadband near-field scanning optical spectroscopy, Optics Express, 25, 13, (15504), (2017).
  • , Tip-Enhanced Raman Spectroscopy: Technique and Recent Advances, Chemical Reviews, 10.1021/acs.chemrev.6b00821, 117, 9, (6447-6466), (2017).
  • , Surface-enhanced Raman spectroscopy: bottlenecks and future directions, Chemical Communications, 10.1039/C7CC05979E, (2017).
  • , Distinguishing Individual DNA Bases in a Network by Non‐Resonant Tip‐Enhanced Raman Scattering, Angewandte Chemie, 129, 20, (5653-5656), (2017).
  • , Nanometal Skin of Plasmonic Heterostructures for Highly Efficient Near-Field Scattering Probes, Scientific Reports, 10.1038/srep31113, 6, 1, (2016).
  • , Near-field absorption imaging by a Raman nano-light source, RSC Advances, 10.1039/C6RA24428A, 6, 114, (113139-113143), (2016).
  • , Versatile Side-Illumination Geometry for Tip-Enhanced Raman Spectroscopy at Solid/Liquid Interfaces, Analytical Chemistry, 10.1021/acs.analchem.6b01080, 88, 14, (7108-7114), (2016).
  • , Raman Microscopy: Analysis of Nanomaterials, Reference Module in Materials Science and Materials Engineering, 10.1016/B978-0-12-803581-8.02593-5, (2016).
  • , Highly efficient plasmonic tip design for plasmon nanofocusing in near-field optical microscopy, Nanoscale, 10.1039/C5NR08548A, 8, 10, (5634-5640), (2016).
  • , Tip-enhanced Raman spectroscopy: plasmid-free vs. plasmid-embedded DNA, The Analyst, 141, 11, (3251), (2016).
  • , Biomolecular SERS Applications, Surface-Enhanced Raman Spectroscopy, 10.1007/978-3-319-23992-7_5, (93-125), (2015).
  • , Concurrent Scanning Double-Tip-Enhanced Raman Scattering by Near-Field Coupling Effect, Plasmonics, 11, 1, (247), (2016).
  • , Nanoscale imaging and identification of a four-component carbon sample, Carbon, 10.1016/j.carbon.2015.09.104, 96, (588-593), (2016).
  • , Vertically-oriented nanoparticle dimer based on focused plasmonic trapping, Optics Express, 24, 14, (16052), (2016).
  • , Selective Detection of RGD-Integrin Binding in Cancer Cells Using Tip Enhanced Raman Scattering Microscopy, Analytical Chemistry, 10.1021/acs.analchem.6b01344, 88, 12, (6547-6553), (2016).
  • , Detection of Protein Glycosylation Using Tip-Enhanced Raman Scattering, Analytical Chemistry, 10.1021/acs.analchem.5b03535, 88, 4, (2105-2112), (2016).
  • , Laser Scanning-Assisted Tip-Enhanced Optical Microscopy for Robust Optical Nanospectroscopy, Applied Spectroscopy, 70, 7, (1239), (2016).
  • , Introduction to Atomic Force Microscopy (AFM) in Biology, Current Protocols in Protein Science, 85, 1, (17.7.1-17.7.21), (2016).
  • , Recent Advances of Plasmon-Enhanced Spectroscopy at Bio-Interfaces, Frontiers of Plasmon Enhanced Spectroscopy Volume 2, 10.1021/bk-2016-1246.ch008, (183-207), (2016).
  • , Single-molecule optomechanics in “picocavities”, Science, 354, 6313, (726), (2016).
  • , Power‐ and polarization dependence of two photon luminescence of single CdSe nanowires with tightly focused cylindrical vector beams of ultrashort laser pulses, Laser & Photonics Reviews, 10, 5, (835-842), (2016).
  • , Nanoscale pH Profile at a Solution/Solid Interface by Chemically Modified Tip-Enhanced Raman Scattering, The Journal of Physical Chemistry C, 120, 27, (14663), (2016).
  • , Preparation of Well‐Defined DNA Samples for Reproducible Nanospectroscopic Measurements, Small, 12, 35, (4821-4829), (2016).
  • , Flexible SERS active detection from novel Ag nano-necklaces as highly reproducible and ultrasensitive tips基于银纳米链的高重复性超灵敏尖端的柔性表面增强拉曼检测衬底, Science China Materials, 10.1007/s40843-016-5056-3, 59, 6, (435-443), (2016).
  • , Tip-Enhanced Raman Spectroscopy, Analytical Chemistry, 10.1021/acs.analchem.6b02093, 88, 19, (9328-9346), (2016).
  • , Localized tip enhanced Raman spectroscopic study of impurity incorporated single GaN nanowire in the sub-diffraction limit, Applied Physics Letters, 10.1063/1.4931730, 107, 12, (123108), (2015).
  • , Label-free determination of lipid composition and secondary protein structure of human salivary noncancerous and cancerous tissues by Raman microspectroscopy, The Analyst, 10.1039/C4AN01394H, 140, 7, (2107-2113), (2015).
  • , Nanoplasmonic Biophotonics, Understanding Biophotonics, 10.1201/b15596-9, (385-439), (2015).
  • , Recent Progress on Plasmon-Enhanced Fluorescence, Nanophotonics, 10.1515/nanoph-2015-0028, 4, 1, (2015).
  • , Rational fabrication of a gold-coated AFM TERS tip by pulsed electrodeposition, Nanoscale, 10.1039/C5NR04263A, 7, 43, (18225-18231), (2015).
  • , Optical antennas with multiple plasmonic nanoparticles for tip-enhanced Raman microscopy, Nanoscale, 7, 41, (17424), (2015).
  • , Distinguishing adjacent molecules on a surface using plasmon-enhanced Raman scattering, Nature Nanotechnology, 10, 10, (865), (2015).
  • , High-resolution Raman imaging of bundles of single-walled carbon nanotubes by tip-enhanced Raman spectroscopy, Canadian Journal of Chemistry, 10.1139/cjc-2014-0247, 93, 1, (51-59), (2015).
  • , Exploring the Nanoscale: Fifteen Years of Tip-Enhanced Raman Spectroscopy, Applied Spectroscopy, 10.1366/15-08014, 69, 12, (1357-1371), (2015).
  • , Spatial resolution in Raman spectroscopy, Faraday Discussions, 177, (9), (2015).
  • , Vibrational Microspectroscopy (MSP), Modern Vibrational Spectroscopy and Micro‐Spectroscopy, (235-250), (2015).
  • , 20 nm–Resolved Stress Profile in SiGe Nano-Stripes Obtained by Tip-Enhanced Raman Spectroscopy, Handbook of Enhanced Spectroscopy, 10.1201/b19175-14, (415-441), (2015).
  • , Tip-enhanced Raman spectroscopy of bradykinin and its B 2 receptor antagonists adsorbed onto colloidal suspended Ag nanowires , Physical Chemistry Chemical Physics, 10.1039/C5CP03438H, 17, 35, (22882-22892), (2015).
  • , Tip-enhanced THz Raman spectroscopy for local temperature determination at the nanoscale, Analytical and Bioanalytical Chemistry, 10.1007/s00216-015-8866-0, 407, 27, (8205-8213), (2015).
  • , Tip-enhanced Raman spectroscopy: tip-related issues, Analytical and Bioanalytical Chemistry, 10.1007/s00216-015-8968-8, 407, 27, (8177-8195), (2015).
  • , Tip-enhanced Raman spectroscopy: principles and applications, EPJ Techniques and Instrumentation, 10.1140/epjti/s40485-015-0019-5, 2, 1, (2015).
  • , Label-Free Surface-Enhanced Raman Spectroscopy Detection of DNA with Single-Base Sensitivity, Journal of the American Chemical Society, 10.1021/jacs.5b01426, 137, 15, (5149-5154), (2015).
  • , Tip-Enhanced Raman Spectroscopy: Principle and Instrumentation, Handbook of Enhanced Spectroscopy, 10.1201/b19175-12, (353-394), (2015).
  • , Si@Cu@Au AFM tips for tip-enhanced Raman spectrum, Science China Chemistry, 10.1007/s11426-015-5353-6, 58, 9, (1494-1500), (2015).
  • , Tip-enhanced Raman scattering—Targeting structure-specific surface characterization for biomedical samples, Advanced Drug Delivery Reviews, 10.1016/j.addr.2015.06.007, 89, (42-56), (2015).
  • , Tuning Localized Surface Plasmon Resonance in Scanning Near-Field Optical Microscopy Probes, ACS Nano, 9, 6, (6297), (2015).
  • , Chirality‐Assisted Ring‐Like Aggregation of Aβ(1–40) at Liquid–Solid Interfaces: A Stereoselective Two‐Step Assembly Process, Angewandte Chemie International Edition, 54, 7, (2245-2250), (2014).
  • , Chirality‐Assisted Ring‐Like Aggregation of Aβ(1–40) at Liquid–Solid Interfaces: A Stereoselective Two‐Step Assembly Process, Angewandte Chemie, 127, 7, (2273-2278), (2014).
  • , Tip Enhancement of Upconversion Photoluminescence from Rare Earth Ion Doped Nanocrystals, ACS Nano, 9, 4, (3617), (2015).
  • , Silicon nitride grids are compatible with correlative negative staining electron microscopy and tip‐enhanced Raman spectroscopy for use in the detection of micro‐organisms, Journal of Applied Microbiology, 116, 6, (1521-1530), (2014).
  • , Scanning Near‐Field Gap‐Mode Microscopy, Handbook of Spectroscopy, (911-940), (2014).
  • , Tip-enhanced near-field optical microscopy, Chem. Soc. Rev., 43, 4, (1248), (2014).
  • , Tip-Enhanced Raman Spectroscopy of Combed Double-Stranded DNA Bundles, The Journal of Physical Chemistry C, 118, 2, (1174), (2014).
  • , Reading Single DNA with DNA Polymerase Followed by Atomic Force Microscopy, Journal of the American Chemical Society, 136, 39, (13754), (2014).
  • , Accurate measurement of enhancement factor in tip-enhanced Raman spectroscopy through elimination of far-field artefacts, Applied Physics Letters, 104, 12, (123106), (2014).
  • , Surface-enhanced Raman scattering and gap-mode tip-enhanced Raman scattering investigations of phthalocyanine molecules on gold nanostructured substrates, Journal of Vacuum Science & Technology B, Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena, 10.1116/1.4890126, 32, 4, (04E110), (2014).
  • , Enhanced single-molecule spectroscopy in highly confined optical fields: from λ/2-Fabry–Pérot resonators to plasmonic nano-antennas, Chem. Soc. Rev., 10.1039/C3CS60357A, 43, 4, (1263-1286), (2014).
  • , Technical Development of Raman Spectroscopy: From Instrumental to Advanced Combined Technologies, Applied Spectroscopy Reviews, 49, 1, (64), (2014).
  • , Molecular plasmonics for nanoscale spectroscopy, Chem. Soc. Rev., 43, 4, (1230), (2014).
  • , Local protonation control using plasmonic activation, Chem. Commun., 50, 76, (11204), (2014).
  • , A Modified Transmission Tip-Enhanced Raman Scattering (TERS) Setup Provides Access to Opaque Samples, Applied Spectroscopy, 10.1366/13-07419, 68, 8, (916-919), (2014).
  • , Tip‐Enhanced Raman Spectroscopy (TERS) for Nanoscale Imaging and Analysis, Frontiers of Surface‐Enhanced Raman Scattering, (139-161), (2014).
  • , State of the art Raman techniques for biological applications, Methods, 10.1016/j.ymeth.2014.02.035, 68, 2, (338-347), (2014).
  • , Tip‐Enhanced Near‐Field Optical Microscopy, Handbook of Spectroscopy, (1585-1610), (2014).
  • , Spectroscopic Imaging of Biological Samples Using Near‐Field Methods, Infrared and Raman Spectroscopic Imaging, (477-512), (2014).
  • , Plasmonic Gradient Effects on High Vacuum Tip‐Enhanced Raman Spectroscopy, Advanced Optical Materials, 2, 1, (74-80), (2013).
  • , Single-molecule surface-enhanced Raman spectroscopy: a perspective on the current status, Physical Chemistry Chemical Physics, 10.1039/c3cp44463e, 15, 15, (5276), (2013).
  • , Localized enhancement of electric field in tip-enhanced Raman spectroscopy using radially and linearly polarized light, Optics Express, 21, 21, (25271), (2013).
  • , Raman Imaging in Biochemical and Biomedical Applications. Diagnosis and Treatment of Breast Cancer, Chemical Reviews, 10.1021/cr300147r, 113, 8, (5766-5781), (2013).
  • , Tip-Enhanced Raman Imaging: An Emergent Tool for Probing Biology at the Nanoscale, ACS Nano, 7, 2, (885), (2013).
  • , Reflection-mode TERS on Insulin Amyloid Fibrils with Top-Visual AFM Probes, Plasmonics, 10.1007/s11468-012-9385-x, 8, 1, (25-33), (2012).
  • , The chemical origin of enhanced signals from tip-enhanced Raman detection of functionalized nanoparticles, The Analyst, 138, 11, (3150), (2013).
  • , Tip-Enhanced Spectroscopy at the Nanoscale, Nanoscale Spectroscopy with Applications, 10.1201/b15615-2, (1-40), (2013).
  • , Raman imaging at biological interfaces: applications in breast cancer diagnosis, Molecular Cancer, 10.1186/1476-4598-12-48, 12, 1, (48), (2013).
  • , Experimental research on the spectral response of tips for tip-enhanced Raman spectroscopy, Journal of Optics, 15, 5, (055006), (2013).
  • , Direct Observation of Single DNA Structural Alterations at Low Forces with Surface-Enhanced Raman Scattering, Biophysical Journal, 104, 1, (156), (2013).
  • , Molecular imaging with surface-enhanced Raman spectroscopy nanoparticle reporters, MRS Bulletin, 38, 08, (625), (2013).
  • , Combined optical and electrochemical methods for studying electrochemistry at the single molecule and single particle level: recent progress and perspectives, Physical Chemistry Chemical Physics, 10.1039/c3cp52756e, 15, 48, (20797), (2013).
  • , Multilayered nano-prism vertex tips for tip-enhanced Raman spectroscopy and imaging, The Analyst, 10.1039/c3an00808h, 138, 19, (5588), (2013).
  • , Parabolic Mirror–Assisted Gap-Mode Optical Ultramicroscopy, Handbook of Molecular Plasmonics, 10.1201/b15328-12, (355-394), (2013).
  • , AFM characterization of biomolecules in physiological environment by an advanced nanofabricated probe, Microscopy Research and Technique, 75, 12, (1723-1731), (2012).
  • , Linear and Nonlinear Spectroscopy at Nano Scale, Optochemical Nanosensors, 10.1201/b13065-17, (385-400), (2012).
  • , Adding Label–Free Chemical Spectroscopy, Hybridizing Surface Probe Microscopies, 10.1201/b12694-6, (2012).
  • , Near-field Raman spectroscopy of biological nanomaterials by in situ laser-induced synthesis of tip-enhanced Raman spectroscopy tips, Optics Letters, 37, 12, (2256), (2012).
  • , Raman Spectroscopy of Biomolecules at Electrode Surfaces, Advances in Electrochemical Science and Engineering, (269-334), (2012).
  • , Tracking of nanoscale structural variations on a single amyloid fibril with tip-enhanced Raman scattering, Journal of Biophotonics, 5, 3, (215), (2012).
  • , Advances in TERS (tip-enhanced Raman scattering) for biochemical applications, Biochemical Society Transactions, 10.1042/BST20120033, 40, 4, (609-614), (2012).
  • , Near-Field Optical Analysis of Plasmonic Nano-Probes for Top-Illumination Tip-Enhanced Raman Scattering, Plasmonics, 7, 2, (359), (2012).
  • , Label‐Free Detection of Nanomolar Unmodified Single‐ and Double‐Stranded DNA by Using Surface‐Enhanced Raman Spectroscopy on Ag and Au Colloids, Chemistry – A European Journal, 18, 17, (5394-5400), (2012).
  • , SERS: Materials, applications, and the future, Materials Today, 10.1016/S1369-7021(12)70017-2, 15, 1-2, (16-25), (2012).
  • , Micrometer-sized gold nanoplates: starch-mediated photochemical reduction synthesis and possibility of application to tip-enhanced Raman scattering (TERS), Physical Chemistry Chemical Physics, 14, 27, (9636), (2012).
  • , Note: Tip enhanced Raman spectroscopy with objective scanner on opaque samples, Review of Scientific Instruments, 83, 6, (066102), (2012).
  • , Surface enhanced Raman scattering for multiplexed detection, The Analyst, 137, 3, (545), (2012).
  • , Subnanometric stabilization of plasmon-enhanced optical microscopy, Nanotechnology, 23, 20, (205503), (2012).
  • , Surface-enhanced Raman spectroscopy (SERS): progress and trends, Analytical and Bioanalytical Chemistry, 10.1007/s00216-011-5631-x, 403, 1, (27-54), (2011).
  • , Introduction to Modern Raman Spectroscopy II‐New Raman Spectroscopic Branch Classified Based on Applied Objects, Raman Spectroscopy and its Application in Nanostructures, (153-183), (2012).
  • , Constant current etching of gold tips suitable for tip-enhanced Raman spectroscopy, Review of Scientific Instruments, 10.1063/1.4763573, 83, 10, (103708), (2012).
  • , Developments in and practical guidelines for tip-enhanced Raman spectroscopy, Nanoscale, 10.1039/C1NR11143D, 4, 6, (1856-1870), (2012).
  • , Label-free detection in biological applications of surface-enhanced Raman scattering, TrAC Trends in Analytical Chemistry, 10.1016/j.trac.2012.05.006, 38, (67-78), (2012).
  • , Bioanalytical application of surface‐ and tip‐enhanced Raman spectroscopy, Engineering in Life Sciences, 12, 2, (131-143), (2012).
  • , Nanoscale distinction of membrane patches - a TERS study of Halobacterium salinarum, Journal of Biophotonics, 5, 7, (582), (2012).
  • , Label-Free Mapping of Osteopontin Adsorption to Calcium Oxalate Monohydrate Crystals by Tip-Enhanced Raman Spectroscopy, Journal of the American Chemical Society, 10.1021/ja3057562, 134, 41, (17076-17082), (2012).
  • , A matter of scale: from far‐field microscopy to near‐field nanoscopy, Laser & Photonics Reviews, 6, 3, (296-332), (2011).
  • , Tip-Enhanced Raman Spectroscopy and Mapping of Graphene Sheets, Applied Spectroscopy Reviews, 47, 5, (371), (2012).
  • , Invited Review Article: Combining scanning probe microscopy with optical spectroscopy for applications in biology and materials science, Review of Scientific Instruments, 10.1063/1.4720102, 83, 6, (061101), (2012).
  • , Detection of Nano-Oxidation Sites on the Surface of Hemoglobin Crystals Using Tip-Enhanced Raman Scattering, Nano Letters, 12, 3, (1555), (2012).
  • , Development and prospect of near-field optical measurements and characterizations, Frontiers of Optoelectronics, 5, 2, (171), (2012).
  • , Principle, system, and applications of tip-enhanced Raman spectroscopy, Science China Physics, Mechanics and Astronomy, 55, 8, (1335), (2012).
  • , Gold Nanoparticles as Probes for Nano-Raman Spectroscopy: Preliminary Experimental Results and Modeling, International Journal of Optics, 2012, (1), (2012).
  • , Nano-optical imaging and spectroscopy of order, phases, and domains in complex solids, Advances in Physics, 10.1080/00018732.2012.737982, 61, 6, (745-842), (2012).
  • , Potential role of atomic force microscopy in systems biology, Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 3, 6, (702-716), (2011).
  • , High‐Resolution Tip‐Enhanced Raman Mapping, Macromolecular Symposia, 305, 1, (26-42), (2011).
  • , Label-Free Detection of Single-Base Mismatches in DNA by Surface-Enhanced Raman Spectroscopy, Angewandte Chemie International Edition, 50, 39, (9058), (2011).
  • , Surface enhanced optical spectroscopies for bioanalysis, The Analyst, 10.1039/c1an15452d, 136, 19, (3831), (2011).
  • , Tip-Enhanced Raman Scattering (TERS) from Hemozoin Crystals within a Sectioned Erythrocyte, Nano Letters, 11, 5, (1868), (2011).
  • , Recent progress in SERS biosensing, Physical Chemistry Chemical Physics, 13, 24, (11551), (2011).
  • , Label-Free Detection of Single-Base Mismatches in DNA by Surface-Enhanced Raman Spectroscopy, Angewandte Chemie, 123, 39, (9224), (2011).
  • , Nanoscale structural analysis using tip-enhanced Raman spectroscopy, Current Opinion in Chemical Biology, 10.1016/j.cbpa.2011.06.020, 15, 5, (719-724), (2011).
  • , Comparative Study of Far-Field and Near-Field Raman Spectra from Silicon-Based Samples and Biological Nanostructures, The Journal of Physical Chemistry C, 10.1021/jp206659z, 115, 50, (24512-24520), (2011).
  • , Physico-mechanical characterisation of cells using atomic force microscopy — Current research and methodologies, Journal of Microbiological Methods, 10.1016/j.mimet.2011.05.021, 86, 2, (131-139), (2011).
  • , Biophysics of single molecules, Biophysics, 56, 5, (858), (2011).
  • , Recent Trends in Surface Characterization and Chemistry with High‐Resolution Scanning Force Methods, Advanced Materials, 23, 4, (477-501), (2010).
  • , Studying Surface Chemistry beyond the Diffraction Limit: 10 Years of TERS, ChemPhysChem, 11, 7, (1365-1373), (2010).
  • , Signal limitations in tip-enhanced Raman scattering: the challenge to become a routine analytical technique, Analytical and Bioanalytical Chemistry, 396, 1, (115), (2010).
  • , Recent advances in single-molecule sequencing, Current Opinion in Biotechnology, 21, 1, (4), (2010).
  • , NOVEL METHOD FOR CANCER CELL APOPTOSIS BY LOCALIZED UV LIGHT WITH GOLD NANOSTRUCTURES: A THEORETICAL INVESTIGATION, Nano, 05, 06, (325), (2010).
  • , Organic photovoltaics: principles and techniques for nanometre scale characterization, Nanotechnology, 10.1088/0957-4484/21/49/492001, 21, 49, (492001), (2010).
  • , Nanoimaging for prion related diseases, Prion, 10.4161/pri.4.4.13125, 4, 4, (265-274), (2014).
  • , Tip-enhanced Raman scattering (TERS) and high-resolution bio nano-analysis—a comparison, Physical Chemistry Chemical Physics, 10.1039/c003316b, 12, 38, (12040), (2010).
  • , Resonance Raman and surface- and tip-enhanced Raman spectroscopy methods to study solid catalysts and heterogeneous catalytic reactions, Chemical Society Reviews, 10.1039/c0cs00044b, 39, 12, (4820), (2010).
  • , Applications of modern micro-Raman spectroscopy for cell analyses, Integrative Biology, 10.1039/b920572a, 2, 2-3, (94), (2010).
  • , Raman Microscopy: Analysis of Nanomaterials, Encyclopedia of Materials: Science and Technology, 10.1016/B978-008043152-9.02247-8, (1-6), (2010).
  • , Surface enhanced Raman evidence for Ag+ complexes of adenine, deoxyadenosine and 5′-dAMP formed in silver colloids, The Analyst, 135, 12, (3034), (2010).
  • , Tip‐enhanced Raman spectroscopy using single‐crystalline Ag nanowire as tip, Journal of Raman Spectroscopy, 41, 10, (1156-1162), (2010).
  • , Plasmonic Crystals: A Platform to Catalog Resonances from Ultraviolet to Near‐Infrared Wavelengths in a Plasmonic Library, Advanced Functional Materials, 20, 4, (529-539), (2009).
  • , Biochemical imaging below the diffraction limit – probing cellular membrane related structures by tip‐enhanced Raman spectroscopy (TERS), Journal of Biophotonics, 3, 7, (455-461), (2010).
  • , Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering, Applied Physics Letters, 10.1063/1.3431628, 96, 21, (213701), (2010).
  • , Structural and catalytic polymorphism of human enzymes: Novel potential platforms for biomedical diagnostics, Biotechnology Advances, 10.1016/j.biotechadv.2009.05.010, 27, 6, (945-959), (2009).
  • , Raman to the limit: tip‐enhanced Raman spectroscopic investigations of a single tobacco mosaic virus, Journal of Raman Spectroscopy, 40, 3, (240-243), (2008).
  • , Tip-enhanced Raman scattering (TERS) of oxidised glutathione on an ultraflat gold nanoplate, Physical Chemistry Chemical Physics, 11, 34, (7360), (2009).
  • , Local field enhancement of an infinite conical metal tip illuminated by a focused beam, Journal of Raman Spectroscopy, 40, 10, (1338), (2009).
  • , Optical fibre SERS sensors, Analytical and Bioanalytical Chemistry, 10.1007/s00216-009-2797-6, 394, 7, (1761-1774), (2009).
  • , Tip‐enhanced Raman scattering studies of histidine on novel silver substrates, Journal of Raman Spectroscopy, 40, 10, (1446-1451), (2009).
  • , Bioanalytical applications of SERS (surface-enhanced Raman spectroscopy), Analytical and Bioanalytical Chemistry, 394, 3, (679), (2009).
  • , Nano-scale analysis of graphene layers by tip-enhanced near-field Raman spectroscopy, Journal of Raman Spectroscopy, 40, 10, (1434), (2009).
  • , Vibrational spectroscopy: a clinical tool for cancer diagnostics, The Analyst, 10.1039/b822130h, 134, 6, (1029), (2009).
  • , Optical nanocrystallography with tip-enhanced phonon Raman spectroscopy, Nature Nanotechnology, 4, 8, (496), (2009).
  • , Tip-enhanced Raman Spectroscopy – Its status, challenges and future directions, Chemical Physics Letters, 10.1016/j.cplett.2009.02.023, 472, 1-3, (1-13), (2009).
  • , Surface-enhanced Raman spectroscopy of dyes: from single molecules to the artists’ canvas, Physical Chemistry Chemical Physics, 10.1039/b904733f, 11, 34, (7350), (2009).
  • , Raman spectroscopy of surfaces, Surface Science, 10.1016/j.susc.2008.11.039, 603, 10-12, (1328-1334), (2009).
  • , High resolution probing of multi wall carbon nanotubes by Tip Enhanced Raman Spectroscopy in gap-mode, Chemical Physics Letters, 469, 1-3, (161), (2009).
  • , Tip‐enhanced Raman spectroscopy for investigating adsorbed nonresonant molecules on single‐crystal surfaces: tip regeneration, probe molecule, and enhancement effect, Journal of Raman Spectroscopy, 40, 10, (1400-1406), (2009).
  • , Performing tip‐enhanced Raman spectroscopy in liquids, Journal of Raman Spectroscopy, 40, 10, (1392-1399), (2009).
  • , Towards a specific characterisation of components on a cell surface—combined TERS‐investigations of lipids and human cells, Journal of Raman Spectroscopy, 40, 10, (1452-1457), (2009).
  • , Parabolic mirror‐assisted tip‐enhanced spectroscopic imaging for non‐transparent materials, Journal of Raman Spectroscopy, 40, 10, (1371-1376), (2009).
  • , Polar phonon mode selection rules in tip‐enhanced Raman scattering, Journal of Raman Spectroscopy, 40, 10, (1413-1419), (2009).
  • , Tip-Enhanced Near-Field Optical Microscopy, Angewandte Chemie International Edition, 47, 43, (8178), (2008).
  • , Tip-enhanced Raman scattering, Chemical Society Reviews, 10.1039/b705967c, 37, 5, (921), (2008).
  • , SURFACE-ENHANCED RAMAN SCATTERING: PRINCIPLES, NANOSTRUCTURES, FABRICATIONS, AND BIOMEDICAL APPLICATIONS, Journal of Innovative Optical Health Sciences, 10.1142/S179354580800025X, 01, 02, (267-284), (2008).
  • , Perspectives for spatially resolved molecular spectroscopy - Raman on the nanometer scale, Journal of Biophotonics, 1, 5, (377), (2008).
  • , Spitzenverstärkte optische Nahfeldmikroskopie, Angewandte Chemie, 120, 43, (8298), (2008).
  • , Towards chemical analysis of nanostructures in biofilms II: tip-enhanced Raman spectroscopy of alginates, Analytical and Bioanalytical Chemistry, 391, 5, (1907), (2008).
  • , Research Highlights, Lab on a Chip, 8, 4, (513), (2008).
  • , The Third Way in Analytical Nanoscience and Nanotechnology, Encyclopedia of Analytical Chemistry, (1-26), (2016).
  • , Analytical Nanoscience and Nanotechnology, Encyclopedia of Analytical Chemistry, (1-28), (2017).
  • , Tip‐enhanced Raman Spectroscopy, Encyclopedia of Analytical Chemistry, (1-30), (2014).
  • , Principle and Application of Tip-enhanced Raman Scattering, Plasmonics, 10.1007/s11468-017-0638-6, (2017).
  • , The evolution of nanopore sequencing, Frontiers in Genetics, 10.3389/fgene.2014.00449, 5, (2015).
  • , Enhanced Vibrational Spectroscopies as Tools for Small Molecule Biosensing, Sensors, 10.3390/s150921239, 15, 9, (21239-21264), (2015).
  • , Subnanometer-resolved chemical imaging via multivariate analysis of tip-enhanced Raman maps, Light: Science & Applications, 10.1038/lsa.2017.98, 6, 11, (e17098), (2017)., (2017).