Communication
Zinc‐Finger Proteins for Site‐Specific Protein Positioning on DNA‐Origami Structures*
*
This work was supported in part by Grants‐in‐Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology (Japan) to T.M. (No. 19021023 and 20241051).
Abstract
Point the finger: Zinc‐finger proteins are convenient and site‐selective adaptors for targeting specific locations within DNA‐origami structures. Orthogonal targeting of the specific locations in the structures was demonstrated by using two adaptors, and the application of Escherichia coli lysate that contained the adaptor‐fused proteins successfully afforded the expected protein–DNA assembly.
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