Paper‐Based Blood Typing Device That Reports Patient’s Blood Type “in Writing”*
This work is supported by the Australian Research Council (ARC). Funding received from ARC through grant numbers DP1094179 and LP110200973 is gratefully acknowledged. The authors thank Haemokinesis for its support through ARC Linkage Project. M.L. and J.T. thank Monash University Research and Graduate School and the Faculty of Engineering for their postgraduate research scholarships. The authors would like to specially thank Dr. E. Perkins and Dr. W. Mosse of the Department of Chemical Engineering, Monash University for proof reading the manuscript.
Abstract
A response in writing: A low‐cost bioactive paper device is designed to perform ABO and RhD blood typing tests, and the paper reports the results in writing. This idea was inspired by the vision of the British author, J. K. Rowling, through her novel “Harry Potter and the Chamber of Secrets” in which a piece of paper could be interrogated for information and unambiguous answers were received from the paper in writing.
Number of times cited: 84
- Yaw-Jen Chang, Ching-Yuan Ho, Xin-Miao Zhou and Hsiu-Rong Yen, Determination of degree of RBC agglutination for blood typing using a small quantity of blood sample in a microfluidic system, Biosensors and Bioelectronics, 102, (234), (2018).
- Rong Cao, Xue Zhang, Weirui Tan and Wei Shen, Precipitation assay meets low wettability on paper: a simple approach for fabricating patterned paper sensors, Cellulose, 25, 1, (583), (2018).
- Taehoon H. Kim, Young Ki Hahn, Jungmin Lee, Danny van Noort and Minseok S. Kim, Solenoid Driven Pressure Valve System: Toward Versatile Fluidic Control in Paper Microfluidics, Analytical Chemistry, (2018).
- Parastoo Afshari and Nabiollah Abolfathi, A novel method for blood‐typing using nitrocellulose, Biomedical Chromatography, 31, 7, (2017).
- Foteini A. Kappi, George Z. Tsogas, Dionysios C. Christodouleas and Dimosthenis L. Giokas, Calibrant-loaded paper-based analytical devices for standard addition quantitative assays, Sensors and Actuators B: Chemical, 10.1016/j.snb.2017.07.007, 253, (860-867), (2017).
- Maxime Huet, Myriam Cubizolles and Arnaud Buhot, Real time observation and automated measurement of red blood cells agglutination inside a passive microfluidic biochip containing embedded reagents, Biosensors and Bioelectronics, 93, (110), (2017).
- Tugce Akyazi, Lourdes Basabe-Desmonts and Fernando Benito-Lopez, Review on microfluidic paper-based analytical devices towards commercialisation, Analytica Chimica Acta, 10.1016/j.aca.2017.11.010, (2017).
- Mingzhu Yang, Wei Zhang, Wenshu Zheng, Fengjing Cao and Xingyu Jiang, Inkjet-printed barcodes for a rapid and multiplexed paper-based assay compatible with mobile devices, Lab on a Chip, 17, 22, (3874), (2017).
- Hong Zhang, Xiaopei Qiu, Yurui Zou, Yanyao Ye, Chao Qi, Lingyun Zou, Xiang Yang, Ke Yang, Yuanfeng Zhu, Yongjun Yang, Yang Zhou and Yang Luo, A dye-assisted paper-based point-of-care assay for fast and reliable blood grouping, Science Translational Medicine, 9, 381, (eaaf9209), (2017).
- Kuldeep Mahato, Ananya Srivastava and Pranjal Chandra, Paper based diagnostics for personalized health care: Emerging technologies and commercial aspects, Biosensors and Bioelectronics, 96, (246), (2017).
- Mingzhu Yang, Wei Zhang, Junchuan Yang, Binfeng Hu, Fengjing Cao, Wenshu Zheng, Yiping Chen and Xingyu Jiang, Skiving stacked sheets of paper into test paper for rapid and multiplexed assay, Science Advances, 3, 12, (eaao4862), (2017).
- Kentaro Yamada, Hiroyuki Shibata, Koji Suzuki and Daniel Citterio, Toward practical application of paper-based microfluidics for medical diagnostics: state-of-the-art and challenges, Lab on a Chip, 17, 7, (1206), (2017).
- Nipapan Ruecha, Kentaro Yamada, Koji Suzuki and Daniel Citterio, (Bio)Chemical Sensors Based on Paper, Materials for Chemical Sensing, 10.1007/978-3-319-47835-7_3, (29-74), (2016).
- Syrena C. Fernandes, Jenna A. Walz, Daniel J. Wilson, Jessica C. Brooks and Charles R. Mace, Beyond Wicking: Expanding the Role of Patterned Paper as the Foundation for an Analytical Platform, Analytical Chemistry, 10.1021/acs.analchem.6b03860, 89, 11, (5654-5664), (2017).
- Jasmina Casals-Terré, Josep Farré-Lladós, Allinson Zuñiga, M. Blanca Roncero and Teresa Vidal, REPlicating RAPid Microfluidics: Self-Replicating Printer for Hydrophobic Pattern Deposition, 3D Printing and Additive Manufacturing, 4, 4, (231), (2017).
- Kentaro Yamada, Koji Suzuki and Daniel Citterio, Text-Displaying Colorimetric Paper-Based Analytical Device, ACS Sensors, 10.1021/acssensors.7b00464, 2, 8, (1247-1254), (2017).
- Yaw-Jen Chang, Yi-Hua Fan, Shia-Chung Chen, Kuan-Hua Lee and Liao-Yong Lou, An Automatic Lab-on-Disc System for Blood Typing, SLAS TECHNOLOGY: Translating Life Sciences Innovation, (247263031774473), (2017).
- Yajuan Sun, Xu Huang and Siowling Soh, Solid‐to‐Liquid Charge Transfer for Generating Droplets with Tunable Charge, Angewandte Chemie, 128, 34, (10110-10114), (2016).
- Lei Wu, Zhichao Dong, Fengyu Li, Haihua Zhou and Yanlin Song, Emerging Progress of Inkjet Technology in Printing Optical Materials, Advanced Optical Materials, 4, 12, (1915-1932), (2016).
- Yajuan Sun, Xu Huang and Siowling Soh, Solid‐to‐Liquid Charge Transfer for Generating Droplets with Tunable Charge, Angewandte Chemie International Edition, 55, 34, (9956-9960), (2016).
- Emilia Witkowska Nery, Paper as a Substrate for Sensors, Analysis of Samples of Clinical and Alimentary Interest with Paper-based Devices, 10.1007/978-3-319-28672-3_1, (1-23), (2016).
- Azadeh Nilghaz, Liyun Guan, Weirui Tan and Wei Shen, Advances of Paper-Based Microfluidics for Diagnostics—The Original Motivation and Current Status, ACS Sensors, 1, 12, (1382), (2016).
- Samuel B. Berry, Syrena C. Fernandes, Anjali Rajaratnam, Nicholas S. DeChiara and Charles R. Mace, Measurement of the hematocrit using paper-based microfluidic devices, Lab on a Chip, 16, 19, (3689), (2016).
- Azadeh Nilghaz, David R. Ballerini, Liyun Guan, Lizi Li and Wei Shen, Red blood cell transport mechanisms in polyester thread-based blood typing devices, Analytical and Bioanalytical Chemistry, 408, 5, (1365), (2016).
- Yuanhong Xu, Mengli Liu, Na Kong and Jingquan Liu, Lab-on-paper micro- and nano-analytical devices: Fabrication, modification, detection and emerging applications, Microchimica Acta, 10.1007/s00604-016-1841-4, 183, 5, (1521-1542), (2016).
- Risto Koivunen, Eveliina Jutila, Roger Bollström and Patrick Gane, Hydrophobic patterning of functional porous pigment coatings by inkjet printing, Microfluidics and Nanofluidics, 20, 6, (2016).
- Jia Li and Joanne Macdonald, Multiplex lateral flow detection and binary encoding enables a molecular colorimetric 7-segment display, Lab on a Chip, 16, 2, (242), (2016).
- Reza Nosrati, Max M. Gong, Maria C. San Gabriel, Armand Zini and David Sinton, Paper-based sperm DNA integrity analysis, Analytical Methods, 8, 33, (6260), (2016).
- Temsiri Songjaroen and Wanida Laiwattanapaisal, Simultaneous forward and reverse ABO blood group typing using a paper-based device and barcode-like interpretation, Analytica Chimica Acta, 921, (67), (2016).
- Deidre E. Damon, Yosef S. Maher, Mengzhen Yin, Fred P. M. Jjunju, Iain S. Young, Stephen Taylor, Simon Maher and Abraham K. Badu-Tawiah, 2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization, The Analyst, 10.1039/C6AN00168H, 141, 12, (3866-3873), (2016).
- Liyun Guan, Lizi Li, Xiaolei Huang, Jianfeng Ji, Junfei Tian, Azadeh Nilghaz and Wei Shen, REMOVED: Bioactive Paper Design for Human Blood Analysis: Paper Property Suitable for Large-scale Sensor Production, Biochemical Engineering Journal, 105, (473), (2016).
- Elizaveta Vereshchagina, Paper Microfluidics, Microfluidics for Biologists, 10.1007/978-3-319-40036-5_7, (165-190), (2016).
- Natasha Yeow, Heather McLiesh, Liyun Guan, Wei Shen and Gil Garnier, Paper-based assay for red blood cell antigen typing by the indirect antiglobulin test, Analytical and Bioanalytical Chemistry, 408, 19, (5231), (2016).
- Carmen Carrasquilla, Jessamyn R. L. Little, Yingfu Li and John D. Brennan, Patterned Paper Sensors Printed with Long‐Chain DNA Aptamers, Chemistry – A European Journal, 21, 20, (7369-7373), (2015).
- Kentaro Yamada, Terence G. Henares, Koji Suzuki and Daniel Citterio, Paper‐Based Inkjet‐Printed Microfluidic Analytical Devices, Angewandte Chemie International Edition, 54, 18, (5294-5310), (2015).
- Kentaro Yamada, Terence G. Henares, Koji Suzuki and Daniel Citterio, Papierbasierte tintenstrahlgedruckte Mikrofluidiksysteme für die Analytik, Angewandte Chemie, 127, 18, (5384-5401), (2015).
- W. L. Then, M. Li, H. McLiesh, W. Shen and G. Garnier, The detection of blood group phenotypes using paper diagnostics, Vox Sanguinis, 108, 2, (186-196), (2014).
- Jia Li, Fabrice Rossignol and Joanne Macdonald, Inkjet printing for biosensor fabrication: combining chemistry and technology for advanced manufacturing, Lab on a Chip, 10.1039/C5LC00235D, 15, 12, (2538-2558), (2015).
- Miaosi Li, Rong Cao, Azadeh Nilghaz, Liyun Guan, Xiwang Zhang and Wei Shen, “Periodic-Table-Style” Paper Device for Monitoring Heavy Metals in Water, Analytical Chemistry, 87, 5, (2555), (2015).
- Miaosi Li, Junfei Tian, Rong Cao, Liyun Guan and Wei Shen, A low-cost forward and reverse blood typing device—a blood sample is all you need to perform an assay, Analytical Methods, 7, 3, (1186), (2015).
- Clémence Sicard, Chad Glen, Brandon Aubie, Dan Wallace, Sana Jahanshahi-Anbuhi, Kevin Pennings, Glen T. Daigger, Robert Pelton, John D. Brennan and Carlos D.M. Filipe, Tools for water quality monitoring and mapping using paper-based sensors and cell phones, Water Research, 70, (360), (2015).
- Xiaofeng Wei, Tian Tian, Shasha Jia, Zhi Zhu, Yanli Ma, Jianjun Sun, Zhenyu Lin and Chaoyong James Yang, Target-Responsive DNA Hydrogel Mediated “Stop-Flow” Microfluidic Paper-Based Analytic Device for Rapid, Portable and Visual Detection of Multiple Targets, Analytical Chemistry, 87, 8, (4275), (2015).
- Whui Lyn Then, Marie-Isabel Aguilar and Gil Garnier, Quantitative blood group typing using surface plasmon resonance, Biosensors and Bioelectronics, 73, (79), (2015).
- Xia Xiang, Zhen Zhang, Jianbin Shi and Fenghong Huang, Paper-based analytical device with colorimetric assay application to the determination of phenolic acids and recognition of Fe3+, RSC Advances, 5, 4, (2615), (2015).
- Julaluk Noiphung, Kwanrutai Talalak, Irin Hongwarittorrn, Naricha Pupinyo, Pannawich Thirabowonkitphithan and Wanida Laiwattanapaisal, A novel paper-based assay for the simultaneous determination of Rh typing and forward and reverse ABO blood groups, Biosensors and Bioelectronics, 67, (485), (2015).
- Natasha Yeow, Heather McLiesh and Gil Garnier, Indirect antiglobulin paper test for red blood cell antigen typing by flow-through method, Analytical Methods, 7, 11, (4645), (2015).
- Heather McLiesh, Scot Sharman and Gil Garnier, Effect of cationic polyelectrolytes on the performance of paper diagnostics for blood typing, Colloids and Surfaces B: Biointerfaces, 133, (189), (2015).
- Kwanrutai Talalak, Julaluk Noiphung, Temsiri Songjaroen, Orawon Chailapakul and Wanida Laiwattanapaisal, A facile low-cost enzymatic paper-based assay for the determination of urine creatinine, Talanta, 10.1016/j.talanta.2015.07.040, 144, (915-921), (2015).
- Kentaro Yamada, Terence G. Henares, Koji Suzuki and Daniel Citterio, Distance-Based Tear Lactoferrin Assay on Microfluidic Paper Device Using Interfacial Interactions on Surface-Modified Cellulose, ACS Applied Materials & Interfaces, 7, 44, (24864), (2015).
- Jun-You Chen, Yi-Ting Huang, Hsin-Hao Chou, Cheng-Po Wang and Chien-Fu Chen, Rapid and inexpensive blood typing on thermoplastic chips, Lab on a Chip, 15, 24, (4533), (2015).
- Mohidus Samad Khan, Tripti Pande and Theo G.M. van de Ven, Qualitative and quantitative detection of T7 bacteriophages using paper based sandwich ELISA, Colloids and Surfaces B: Biointerfaces, 132, (264), (2015).
- Wendell Karlos Tomazelli Coltro, Chao‐Min Cheng, Emanuel Carrilho and Dosil Pereira Jesus, Recent advances in low‐cost microfluidic platforms for diagnostic applications, ELECTROPHORESIS, 35, 16, (2309-2324), (2014).
- Yajing Song, Péter Gyarmati, Ana Catarina Araújo, Joakim Lundeberg, Harry Brumer and Patrik L. Ståhl, Visual Detection of DNA on Paper Chips, Analytical Chemistry, 10.1021/ac403196b, 86, 3, (1575-1582), (2014).
- Ioannis N. Katis, Judith A. Holloway, Jens Madsen, Saul N. Faust, Spiros D. Garbis, Peter J. S. Smith, David Voegeli, Dan L. Bader, Robert W. Eason and Collin L. Sones, Paper-based colorimetric enzyme linked immunosorbent assay fabricated by laser induced forward transfer, Biomicrofluidics, 10.1063/1.4878696, 8, 3, (036502), (2014).
- Lizi Li, Xiaolei Huang, Wen Liu and Wei Shen, Control Performance of Paper-Based Blood Analysis Devices through Paper Structure Design, ACS Applied Materials & Interfaces, 6, 23, (21624), (2014).
- Anni Määttänen, Adyary Fallarero, Janni Kujala, Petri Ihalainen, Pia Vuorela and Jouko Peltonen, Printed paper-based arrays as substrates for biofilm formation, AMB Express, 4, 1, (2014).
- Azadeh Nilghaz, Liyuan Zhang, Miaosi Li, David R. Ballerini and Wei Shen, Understanding Thread Properties for Red Blood Cell Antigen Assays: Weak ABO Blood Typing, ACS Applied Materials & Interfaces, 6, 24, (22209), (2014).
- , Rapid Detection of Transition Metals in Welding Fumes Using Paper-Based Analytical Devices, The Annals of Occupational Hygiene, (2014).
- Liyun Guan, Junfei Tian, Rong Cao, Miaosi Li, Zhaoxiang Cai and Wei Shen, Barcode-Like Paper Sensor for Smartphone Diagnostics: An Application of Blood Typing, Analytical Chemistry, 86, 22, (11362), (2014).
- Wei-Ju Liao, Pradip Kumar Roy and Surojit Chattopadhyay, An ink-jet printed, surface enhanced Raman scattering paper for food screening, RSC Adv., 10.1039/C4RA04821K, 4, 76, (40487-40493), (2014).
- Vinay Khatri, Katalin Halász, Lidija V. Trandafilović, Suzana Dimitrijević-Branković, Paritosh Mohanty, Vladimir Djoković and Levente Csóka, ZnO-modified cellulose fiber sheets for antibody immobilization, Carbohydrate Polymers, 109, (139), (2014).
- Liyun Guan, Rong Cao, Junfei Tian, Heather McLiesh, Gil Garnier and Wei Shen, A preliminary study on the stabilization of blood typing antibodies sorbed into paper, Cellulose, 21, 1, (717), (2014).
- Miaosi Li, Whui Lyn Then, Lizi Li and Wei Shen, Paper-based device for rapid typing of secondary human blood groups, Analytical and Bioanalytical Chemistry, 406, 3, (669), (2014).
- Lei Ge, Jinghua Yu, Shenguang Ge and Mei Yan, Lab-on-paper-based devices using chemiluminescence and electrogenerated chemiluminescence detection, Analytical and Bioanalytical Chemistry, 10.1007/s00216-014-7756-1, 406, 23, (5613-5630), (2014).
- Piotr Lisowski and Paweł K. Zarzycki, Microfluidic Paper-Based Analytical Devices (μPADs) and Micro Total Analysis Systems (μTAS): Development, Applications and Future Trends, Chromatographia, 10.1007/s10337-013-2413-y, 76, 19-20, (1201-1214), (2013).
- Zhengyang Zhao, Junfei Tian, Zhangxiong Wu, Jian Liu, Dongyuan Zhao, Wei Shen and Lizhong He, Enhancing enzymatic stability of bioactive papers by implanting enzyme-immobilized mesoporous silica nanorods into paper, Journal of Materials Chemistry B, 10.1039/c3tb20953a, 1, 37, (4719), (2013).
- Julaluk Noiphung, Temsiri Songjaroen, Wijitar Dungchai, Charles S. Henry, Orawon Chailapakul and Wanida Laiwattanapaisal, Electrochemical detection of glucose from whole blood using paper-based microfluidic devices, Analytica Chimica Acta, 788, (39), (2013).
- Maria Peixoto Sousa and João Filipe Mano, Superhydrophobic Paper in the Development of Disposable Labware and Lab-on-Paper Devices, ACS Applied Materials & Interfaces, 5, 9, (3731), (2013).
- A. Nilghaz, D. R. Ballerini and W. Shen, Exploration of microfluidic devices based on multi-filament threads and textiles: A review, Biomicrofluidics, 7, 5, (051501), (2013).
- Ying Hui Ngo, Dan Li, George P. Simon and Gil Garnier, Effect of cationic polyacrylamide dissolution on the adsorption state of gold nanoparticles on paper and their Surface Enhanced Raman Scattering properties, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 420, (46), (2013).
- Sylwia Makulska, Slawomir Jakiela and Piotr Garstecki, A micro-rheological method for determination of blood type, Lab on a Chip, 13, 14, (2796), (2013).
- Lizi Li, Junfei Tian, David Ballerini, Miaosi Li and Wei Shen, A study of the transport and immobilisation mechanisms of human red blood cells in a paper-based blood typing device using confocal microscopy, The Analyst, 138, 17, (4933), (2013).
- Pratikkumar Shah, Xuena Zhu and Chen-zhong Li, Development of paper-based analytical kit for point-of-care testing, Expert Review of Molecular Diagnostics, 13, 1, (83), (2013).
- Anni Määttänen, Ulriika Vanamo, Petri Ihalainen, Petri Pulkkinen, Heikki Tenhu, Johan Bobacka and Jouko Peltonen, A low-cost paper-based inkjet-printed platform for electrochemical analyses, Sensors and Actuators B: Chemical, 177, (153), (2013).
- Emilia W. Nery and Lauro T. Kubota, Sensing approaches on paper-based devices: a review, Analytical and Bioanalytical Chemistry, 10.1007/s00216-013-6911-4, 405, 24, (7573-7595), (2013).
- Lizi Li, Junfei Tian, Miaosi Li and Wei Shen, Superhydrophobic surface supported bioassay – An application in blood typing, Colloids and Surfaces B: Biointerfaces, 10.1016/j.colsurfb.2013.01.049, 106, (176-180), (2013).
- Helka Juvonen, Anni Määttänen, Patrick Laurén, Petri Ihalainen, Arto Urtti, Marjo Yliperttula and Jouko Peltonen, Biocompatibility of printed paper-based arrays for 2-D cell cultures, Acta Biomaterialia, 10.1016/j.actbio.2013.01.033, 9, 5, (6704-6710), (2013).
- Martina Hitzbleck and Emmanuel Delamarche, Reagents in microfluidics: an ‘in’ and ‘out’ challenge, Chemical Society Reviews, 10.1039/c3cs60118h, 42, 21, (8494), (2013).
- Nicole K. Thom, Gregory G. Lewis, Matthew J. DiTucci and Scott T. Phillips, Two general designs for fluidic batteries in paper-based microfluidic devices that provide predictable and tunable sources of power for on-chip assays, RSC Advances, 3, 19, (6888), (2013).
- Ali Kemal Yetisen, Muhammad Safwan Akram and Christopher R. Lowe, Paper-based microfluidic point-of-care diagnostic devices, Lab on a Chip, 10.1039/c3lc50169h, 13, 12, (2210), (2013).
- Xue E. Wu, Yuan Zan Guo, Meng Ying Chen and Xiao Dong Chen, Fabrication of flexible and disposable enzymatic biofuel cells, Electrochimica Acta, 98, (20), (2013).
- Jielong Su, Mohammad Al-Tamimi and Gil Garnier, Engineering paper as a substrate for blood typing bio-diagnostics, Cellulose, 19, 5, (1749), (2012).
- Junfei Tian, Purim Jarujamrus, Lizi Li, Miaosi Li and Wei Shen, Strategy To Enhance the Wettability of Bioacive Paper-Based Sensors, ACS Applied Materials & Interfaces, 10.1021/am301699m, 4, 12, (6573-6578), (2012).
- Yan Zhang, Lina Zhang, Kang Cui, Shenguang Ge, Xin Cheng, Mei Yan, Jinghua Yu and Hong Liu, Flexible Electronics Based on Micro/Nanostructured Paper, Advanced Materials, 1801588, (2018).





