Back Cover: Cinnamic Acid/Chloroquinoline Conjugates as Potent Agents against Chloroquine‐Resistant Plasmodium falciparum (ChemMedChem 9/2012)

Abstract

The back cover picture shows a novel warhead against intraerythrocytic malaria parasites. Chloroquinoline–cinnamic acid conjugates display activities in the low nanomolar range against chloroquine‐resistant Plasmodium falciparum. In the image, the general structure of such conjugates is depicted targeting a blood schizont of the 3D7 Pf strain (image from Gut and Rosenthal). For more details, see the Communication by Paula Gomes et al. on p. 1537 ff.