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Research Article

Analysis of 17 Y‐STR loci haplotype and Y‐chromosome haplogroup distribution in five Chinese ethnic groups

Ying Wang

Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat‐sen University, Guangzhou, P. R. China

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Chao Liu

Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, P. R. China

Guangzhou Institute of Criminal Science and Technology, Guangzhou, P. R. China

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Chu‐chu Zhang

Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat‐sen University, Guangzhou, P. R. China

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Ran Li

Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat‐sen University, Guangzhou, P. R. China

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Yue LI

Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, P. R. China

Guangzhou Institute of Criminal Science and Technology, Guangzhou, P. R. China

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Xue‐ling Ou

Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat‐sen University, Guangzhou, P. R. China

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Hong‐yu Sun

Corresponding Author

Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat‐sen University, Guangzhou, P. R. China

Correspondence: Prof. Hongyu Sun Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat‐sen University, No. 74 Zhongshan Road II, Guangzhou 510089, P. R. China

E‐mail: sunhy@mail.sysu.edu.cn

Fax: +86‐20 87334353

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First published: 23 June 2015
Cited by: 3

Abstract

To investigate genetic diversity in Chinese populations, 706 unrelated male individuals from five ethnic groups (Han, Korean, Hui, Mongolian, and Tibetan, respectively) were analyzed with 17 Y‐chromosomal STRs. The haplotype diversity was 0.99985 in the combined data. A total of 675 distinct haplotypes were observed, of which 649 were unique. Y‐chromosome haplogroups in the five groups were also predicted with Y‐STR haplotypes. Genetic distance between the five studied ethnic groups and other published groups was analyzed by analysis of molecular variance and visualized in a multidimensional scaling plot. In conclusion, the 17 Y‐STR loci are highly polymorphic markers in the five groups and hence are very useful in forensic application, population genetics, and human evolution studies.

Number of times cited: 3

  • , The finding of disaccord in haplogroup prediction by online software in a father-son pair, Forensic Science International: Genetics Supplement Series, 6, (e175), (2017).
  • , SNP typing using the HID-Ion AmpliSeq™ Identity Panel in a southern Chinese population, International Journal of Legal Medicine, (2017).
  • , Molecular Genealogy of a Mongol Queen’s Family and Her Possible Kinship with Genghis Khan, PLOS ONE, 11, 9, (e0161622), (2016).