Volume 90, Issue 2
Article

A histochemical study of hypertrophy and ischaemic injury of rat liver with special reference to changes in lysosomes

J. F. R. Kerr

Department of Morbid Anatomy, University College Hospital Medical School, London

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First published: October 1965
Citations: 143
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Number of times cited according to CrossRef: 143

  • Regulation of ferroptosis in cancer cells by YAP/TAZ and Hippo pathways: The therapeutic implications, Genes & Diseases, 10.1016/j.gendis.2020.05.004, (2020).
  • The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction, F1000Research, 10.12688/f1000research.24447.1, 9, (626), (2020).
  • Ferroptotic agent‐induced endoplasmic reticulum stress response plays a pivotal role in the autophagic process outcome, Journal of Cellular Physiology, 10.1002/jcp.29571, 235, 10, (6767-6778), (2020).
  • The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction, F1000Research, 10.12688/f1000research.24447.3, 9, (626), (2020).
  • The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction, F1000Research, 10.12688/f1000research.24447.2, 9, (626), (2020).
  • C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity, Frontiers in Immunology, 10.3389/fimmu.2020.00251, 11, (2020).
  • Measles virus phosphoprotein inhibits apoptosis and enhances clonogenic and migratory properties in HeLa cells, Journal of Biosciences, 10.1007/s12038-018-9834-6, 44, 1, (2019).
  • Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis, Cell & Bioscience, 10.1186/s13578-019-0292-0, 9, 1, (2019).
  • Berberine as a potential autophagy modulator, Journal of Cellular Physiology, 10.1002/jcp.28325, 234, 9, (14914-14926), (2019).
  • Apoptosis as the Major Cause of Embryonic Mortality in Cattle, New Insights into Theriogenology, 10.5772/intechopen.74197, (2018).
  • The Development of the Concept of Ferroptosis, Free Radical Biology and Medicine, 10.1016/j.freeradbiomed.2018.09.043, (2018).
  • Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrosterone Promotes Beneficial Effects on Human Health, Dehydroepiandrosterone, 10.1016/bs.vh.2018.01.006, (273-307), (2018).
  • Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles, Autophagy, 10.1080/15548627.2018.1509171, (1-30), (2018).
  • Ganoderic acid, lanostanoid triterpene: a key player in apoptosis, Investigational New Drugs, 10.1007/s10637-017-0526-0, 36, 1, (136-143), (2017).
  • Kerr, John (1934–), Pioneers in Pathology, 10.1007/978-3-319-41995-4_2427, (283-288), (2017).
  • Dying cells actively regulate adaptive immune responses, Nature Reviews Immunology, 10.1038/nri.2017.9, 17, 4, (262-275), (2017).
  • Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development, Development of the Cerebellum from Molecular Aspects to Diseases, 10.1007/978-3-319-59749-2, (153-178), (2017).
  • Regulation of stressed-induced cell death by the Bcl-2 family of apoptotic proteins, Molecular Membrane Biology, 10.1080/09687688.2017.1400600, 33, 6-8, (89-99), (2017).
  • Mille modis morimur: We die in a thousand ways, Apoptosis, 10.1007/s10495-016-1328-0, 22, 2, (169-174), (2016).
  • DNA Fragmentation Follows Delayed Neuronal Death in CA1 Neurons Exposed to Transient Global Ischemia in the Rat, Journal of Cerebral Blood Flow & Metabolism, 10.1097/00004647-199709000-00006, 17, 9, (967-976), (2016).
  • Apoptosis and Necrosis after Reversible Focal Ischemia: An in Situ DNA Fragmentation Analysis, Journal of Cerebral Blood Flow & Metabolism, 10.1097/00004647-199603000-00002, 16, 2, (186-194), (2016).
  • Events in Dying Cells, Proceedings of the Royal Society of Medicine, 10.1177/003591576706000331, 60, 3, (271-275), (2016).
  • The Role of Lysosomes in Pathology, Proceedings of the Royal Society of Medicine, 10.1177/003591576605900940, 59, 9, (877-879), (2016).
  • 60 YEARS OF NEUROENDOCRINOLOGY: MEMOIR: Geoffrey Harris and my brush with his unit, Journal of Endocrinology, 10.1530/JOE-15-0049, 226, 2, (T1-T11), (2015).
  • Intracellular Signal Modulation by Nanomaterials, Nanomaterial, 10.1007/978-94-017-8739-0_7, (111-134), (2014).
  • Molecular Biology of Brain Injury: 2012, Pediatric Critical Care Medicine, 10.1007/978-1-4471-6356-5, (535-553), (2014).
  • Historical Perspective: The Seven Ages of Cell Death Research, Cell Death, 10.1007/978-1-4614-9302-0, (1-14), (2014).
  • Ion channels and apoptosis in cancer, Philosophical Transactions of the Royal Society B: Biological Sciences, 10.1098/rstb.2013.0104, 369, 1638, (20130104-20130104), (2014).
  • Cyclosporine A Induces Apoptotic and Autophagic Cell Death in Rat Pituitary GH3 Cells, PLoS ONE, 10.1371/journal.pone.0108981, 9, 10, (e108981), (2014).
  • Macrophages and Recently Identified Forms of Cell Death, International Reviews of Immunology, 10.3109/08830185.2013.771183, 33, 1, (9-22), (2013).
  • A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin, Metallomics, 10.1039/c3mt20252f, 5, 5, (514), (2013).
  • Apoptosis, Colloquium Series on Building Blocks of the Cell: Cell Structure and Function, 10.4199/C00080ED1V01Y201303BBC003, 1, 3, (1-101), (2013).
  • Targeting disease through novel pathways of apoptosis and autophagy, Expert Opinion on Therapeutic Targets, 10.1517/14728222.2012.719499, 16, 12, (1203-1214), (2012).
  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012, Cell Death and Differentiation, 10.1038/cdd.2011.96, 19, 1, (107-120), (2011).
  • Biochemistry and Cellular Mechanisms of Apoptosis in Vascular Smooth Muscle and Endothelial Cells, Textbook of Pulmonary Vascular Disease, 10.1007/978-0-387-87429-6, (347-356), (2011).
  • Life and Death of Lymphocytes: A Volume Regulation Affair, Cellular Physiology and Biochemistry, 10.1159/000335864, 28, 6, (1079-1088), (2011).
  • Evaluation of Apoptosis in the Liver Preserved by Simple Hypothermia Using Histidine-Tryptophan-Ketoglutarate and Prolactin-Modified Histidine-Tryptophan-Ketoglutarate Solution, Transplantation Proceedings, 10.1016/j.transproceed.2011.08.066, 43, 8, (2900-2902), (2011).
  • Can α-radioimmunotherapy increase efficacy for the systemic control of cancer?, Immunotherapy, 10.2217/imt.11.13, 3, 4, (455-458), (2011).
  • In vivo real-time imaging of the liver with confocal endomicroscopy permits visualization of the temporospatial patterns of hepatocyte apoptosis, American Journal of Physiology-Gastrointestinal and Liver Physiology, 10.1152/ajpgi.00175.2011, 301, 5, (G764-G772), (2011).
  • ‘Blue Sky’ epidemiology: definition, examples and a plea for understanding, Australian and New Zealand Journal of Public Health, 10.1111/j.1753-6405.2010.00664.x, 35, 1, (4-6), (2011).
  • Expression of Measles Virus Nucleoprotein Induces Apoptosis and Modulates Diverse Functional Proteins in Cultured Mammalian Cells, PLoS ONE, 10.1371/journal.pone.0018765, 6, 4, (e18765), (2011).
  • Cell death assays for drug discovery, Nature Reviews Drug Discovery, 10.1038/nrd3373, 10, 3, (221-237), (2011).
  • Neural plasticity and functional recovery of human central nervous system with special reference to spinal cord injury, Spinal Cord, 10.1038/sc.2010.124, 49, 4, (486-492), (2010).
  • Role of Ion Transport in Control of Apoptotic Cell Death, Comprehensive Physiology, 10.1002/cphy, (2037-2061), (2010).
  • Melatonin suppresses cyclosporine A‐induced autophagy in rat pituitary GH3 cells, Journal of Pineal Research, 10.1111/j.1600-079X.2010.00744.x, 48, 3, (204-211), (2010).
  • SERPINB3, apoptosis and autoimmunity, Autoimmunity Reviews, 10.1016/j.autrev.2009.03.011, 9, 2, (108-112), (2009).
  • Molecular Biology of Brain Injury, The Central Nervous System in Pediatric Critical Illness and Injury, 10.1007/978-1-84800-993-6, (1-12), (2009).
  • Apoptosis, Apoptotic Chromatin Changes, 10.1007/978-1-4020-9561-0, (203-292), (2009).
  • A chitosan–dipotassium orthophosphate hydrogel for the delivery of Doxorubicin in the treatment of osteosarcoma, Biomaterials, 10.1016/j.biomaterials.2009.03.022, 30, 21, (3605-3613), (2009).
  • Apoptosis and cancer: the genesis of a research field, Nature Reviews Cancer, 10.1038/nrc2663, 9, 7, (501-507), (2009).
  • Fas Antigen/APO-1 (CD95) Expression on Myeloma Cells, Leukemia & Lymphoma, 10.3109/10428199609054860, 23, 5-6, (521-531), (2009).
  • Toxicology Down Under: Past Achievements, Present Realities, and Future Prospects, Chemical Research in Toxicology, 10.1021/tx8001252, 21, 5, (967-970), (2008).
  • A Personal History of the Development of the Apoptosis Concept, Beyond Apoptosis, 10.3109/9781420020502, (1-11), (2008).
  • Mechanisms of ischemic brain damage, Neuropharmacology, 10.1016/j.neuropharm.2008.01.005, 55, 3, (310-318), (2008).
  • Having a swell time – mitochondrial morphology and plant cell death programmes, Journal of Microscopy, 10.1111/j.1365-2818.2008.02037.x, 231, 2, (215-224), (2008).
  • The significance of cell death by apoptosis in hepatobiliary disease, Journal of Gastroenterology and Hepatology, 10.1111/j.1440-1746.1987.tb00152.x, 2, 1, (77-96), (2008).
  • Effects of liver ischemia on degradation of different classes of hepatic proteins, Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1984.tb07373.x, 120, 1, (61-66), (2008).
  • Altered growth response of oral mucosal keratinocytes in p53‐deficient mice, Journal of Oral Pathology & Medicine, 10.1111/j.1600-0714.1999.tb02056.x, 28, 8, (371-376), (2007).
  • Autofluorescent granular cells in oral mucosal hyperplasias, Histopathology, 10.1111/j.1365-2559.1977.tb01675.x, 1, 5, (375-384), (2007).
  • Ethanol‐Induced Apoptosis and Oxidative Stress in Hepatocytes, Alcoholism: Clinical and Experimental Research, 10.1111/j.1530-0277.1996.tb01804.x, 20, s9, (340A-346A), (2006).
  • Semisynthesis and Screening of a Small Library of Pro‐Apoptotic Squamocin Analogues: Selection and Study of a Benzoquinone Hybrid with an Improved Biological Profile., ChemMedChem, 10.1002/cmdc.200500011, 1, 1, (118-129), (2005).
  • Apoptosis – A Brief Review, Neuroembryology and Aging, 10.1159/000085404, 3, 1, (47-59), (2005).
  • Apoptosis in cultured rat hepatocytes: The effects of tumour necrosis factor α and interferon γ, The Journal of Pathology, 10.1002/path.1711650309, 165, 3, (247-253), (2005).
  • An ultrastructural study of spontaneous cell death in a mouse mastocytoma with particular reference to dark cells, The Journal of Pathology, 10.1002/path.1711530408, 153, 4, (345-355), (2005).
  • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis, The Journal of Pathology, 10.1002/path.1711420112, 142, 1, (67-77), (2005).
  • Experimental paracetamol‐induced hepatic necrosis: A light‐and electron‐microscope, and histochemical study, The Journal of Pathology, 10.1002/path.1711160104, 116, 1, (17-29), (2005).
  • The digestion of cellular fragments within phagolysosomes in carcinoma cells, The Journal of Pathology, 10.1002/path.1711080107, 108, 1, (55-58), (2005).
  • Malakoplakia: An electron‐microscope and chemical study, The Journal of Pathology, 10.1002/path.1711070408, 107, 4, (289-294), (2005).
  • A suggested explanation for the paradoxically slow growth rate of basal‐cell carcinomas that contain numerous mitotic figures, The Journal of Pathology, 10.1002/path.1711070107, 107, 1, (41-44), (2005).
  • Light‐ and electon‐microscope observations of the liver of the mouse after a single oral dose of ngaione, The Journal of Pathology, 10.1002/path.1711060406, 106, 4, (251-259), (2005).
  • Shrinkage necrosis: A distinct mode of cellular death, The Journal of Pathology, 10.1002/path.1711050103, 105, 1, (13-20), (2005).
  • A histochemical study of the bile ducts in long‐term biliary obstruction in the rat, The Journal of Pathology, 10.1002/path.1711030305, 103, 3, (163-175), (2005).
  • An electron‐microscope study of liver cell necrosis due to heliotrine, The Journal of Pathology, 10.1002/path.1710970314, 97, 3, (557-562), (2005).
  • Partial hepatectomy with or without endotoxin does not promote apoptosis in the rat liver, Journal of Surgical Research, 10.1016/S0022-4804(03)00159-8, 116, 1, (1-10), (2004).
  • Uncoupling Cell Shrinkage from Apoptosis Reveals That Na + Influx Is Required for Volume Loss during Programmed Cell Death , Journal of Biological Chemistry, 10.1074/jbc.M303516200, 278, 40, (39176-39184), (2003).
  • The Nobel Prize and Pathology, The American Journal of Surgical Pathology, 10.1097/00000478-200306000-00019, 27, 6, (846-847), (2003).
  • Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line, Toxicology in Vitro, 10.1016/S0887-2333(03)00014-6, 17, 3, (279-287), (2003).
  • Apoptosis Timeline, Cell Death & Differentiation, 10.1038/sj.cdd.4400990, 9, 4, (349-354), (2002).
  • History of the events leading to the formulation of the apoptosis concept, Toxicology, 10.1016/S0300-483X(02)00457-2, 181-182, (471-474), (2002).
  • On the origin, evolution and nature of programmed cell death: a timeline of four billion years, Cell Death & Differentiation, 10.1038/sj.cdd.4400950, 9, 4, (367-393), (2002).
  • Apoptosis in Cardiac Transplant Rejection, Cardiac Allograft Rejection, 10.1007/978-1-4615-1649-1, (89-100), (2001).
  • APOPTOSIS IN CARDIAC TRANSPLANT REJECTION, Cardiology Clinics, 10.1016/S0733-8651(05)70200-9, 19, 1, (141-154), (2001).
  • Virchow and Apoptosis, The American Journal of Pathology, 10.1016/S0002-9440(10)64105-3, 158, 4, (1543), (2001).
  • Mechanisms of Neuronal Cell Death After Ischemic Injury to the Brain, Current Review of Cerebrovascular Disease, 10.1007/978-1-4684-0001-4, (15-24), (2001).
  • Co-existence of necrosis and apoptosis in rat hippocampus following transient forebrain ischemia, Neuroscience Research, 10.1016/S0168-0102(00)00107-3, 37, 2, (113-125), (2000).
  • On the Nature of Cell Death During Remodeling of Hypertrophied Human Myocardium, Journal of Molecular and Cellular Cardiology, 10.1006/jmcc.1999.1064, 32, 1, (161-175), (2000).
  • John Kerr and apoptosis, Medical Journal of Australia, 10.5694/j.1326-5377.2000.tb139362.x, 173, 11-12, (616-617), (2000).
  • Apoptose et mitochondries, Annales de l'Institut Pasteur / Actualités, 10.1016/S0924-4204(01)80002-0, 11, 4, (19-36), (2000).
  • Apoptotic Cells Associated with Wallerian Degeneration After Experimental Spinal Cord Injury: A Possible Mechanism of Oligodendroglial Death, Journal of Neurotrauma, 10.1089/neu.1999.16.945, 16, 10, (945-952), (1999).
  • A Personal Account of Events Leading to the Definition of the Apoptosis Concept, Apoptosis: Biology and Mechanisms, 10.1007/978-3-540-69184-6_1, (1-10), (1999).
  • Delayed Neuronal Death in Experimental Ischemic Stroke, Maturation Phenomenon in Cerebral Ischemia III, 10.1007/978-3-642-58602-6, (267-273), (1999).
  • Apoptosis, Arteriosclerosis, Thrombosis, and Vascular Biology, 10.1161/01.ATV.19.1.14, 19, 1, (14-22), (1999).
  • Hepatic Apoptotic Activity Following Transient Normothermic Inflow Occlusion and Reperfusion in the Swine Model, Journal of Surgical Research, 10.1006/jsre.1999.5703, 86, 1, (70-78), (1999).
  • Embolization of Portal Vein Branches Induces Hepatocyte Replication in Swine: A Potential Step in Hepatic Gene Therapy, Radiology, 10.1148/radiology.210.2.r99fe10467, 210, 2, (467-477), (1999).
  • Apoptosis in neurodegenerative diseases: the role of mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, 10.1016/S0005-2728(98)00167-4, 1410, 2, (195-213), (1999).
  • APOPTOSIS OF EPITHELIAL CELLS IN VIVO INVOLVES TISSUE TRANSGLUTAMINASE UPREGULATION, The Journal of Pathology, 10.1002/(SICI)1096-9896(199607)179:3<288::AID-PATH574>3.0.CO;2-M, 179, 3, (288-293), (1999).
  • Expression of the Platelet-activating Factor Receptor Results in Enhanced Ultraviolet B Radiation-induced Apoptosis in a Human Epidermal Cell Line, Journal of Biological Chemistry, 10.1074/jbc.273.30.18891, 273, 30, (18891-18897), (1998).
  • Placental apoptosis in normal and abnormal pregnancy, Current Obstetrics & Gynaecology, 10.1016/S0957-5847(98)80005-X, 8, 1, (13-20), (1998).
  • VENTRICULAR REMODELING, Cardiology Clinics, 10.1016/S0733-8651(05)70039-4, 16, 4, (623-632), (1998).
  • Apoptosis in heart failure, Progress in Cardiovascular Diseases, 10.1016/S0033-0620(98)80003-0, 40, 6, (549-562), (1998).
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