Volume 25, Issue 22
Research Article

Bayesian semi‐parametric ROC analysis

Alaattin Erkanli

Corresponding Author

E-mail address: al@psych.duhs.duke.edu

Department of Biostatistics and Bioinformatics, Duke University Medical School, Box 3454, Durham, NC 27710, U.S.A.

Department of Biostatistics and Bioinformatics, Duke University Medical School, Box 3454, Durham, NC 27710, U.S.A.Search for more papers by this author
Minje Sung

E-mail address: sungmj@ajou.ac.kr

Department of Business Administration, Ajou University, Suwon, Kyungki‐Do, Korea

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E. Jane Costello

Department of Psychiatry and Behavioral Sciences, Duke University Medical School, Developmental Epidemiology Center, Box 3454, Durham, NC 27710, U.S.A.

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Adrian Angold

Department of Psychiatry and Behavioral Sciences, Duke University Medical School, Developmental Epidemiology Center, Box 3454, Durham, NC 27710, U.S.A.

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First published: 13 January 2006
Citations: 39

Abstract

This paper describes a semi‐parametric Bayesian approach for estimating receiver operating characteristic (ROC) curves based on mixtures of Dirichlet process priors (MDP). We address difficulties in modelling the underlying distribution of screening scores due to non‐normality that may lead to incorrect choices of diagnostic cut‐offs and unreliable estimates of prevalence of the disease. MDP is a robust tool for modelling non‐standard diagnostic distributions associated with imperfect classification of an underlying diseased population, for example, when a diagnostic test is not a gold standard. For posterior computations, we propose an efficient Gibbs sampling framework based on a finite‐dimensional approximation to MDP. We show, using both simulated and real data sets, that MDP modelling for ROC curve estimation closely parallels the frequentist kernel density estimation (KDE) approach. Copyright © 2006 John Wiley & Sons, Ltd.

Number of times cited according to CrossRef: 39

  • A Bayesian semiparametric approach to correlated ROC surfaces with stochastic order constraints, Biometrics, 10.1111/biom.12997, 75, 2, (539-550), (2019).
  • Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard – An update, PLOS ONE, 10.1371/journal.pone.0223832, 14, 10, (e0223832), (2019).
  • Non-monotone transformation of biomarkers to improve diagnostic and screening accuracy in a DNA methylation study with trichotomous phenotypes, Statistical Methods in Medical Research, 10.1177/0962280219882047, (096228021988204), (2019).
  • Affinity-based measures of biomarker performance evaluation, Statistical Methods in Medical Research, 10.1177/0962280219846157, (096228021984615), (2019).
  • An approach to optimizing abstaining area for small sample data classification, Expert Systems with Applications, 10.1016/j.eswa.2017.11.013, 95, (153-161), (2018).
  • Use of Bivariate Dirichlet Process Mixture Spatial Model to Estimate Active Transportation-Related Crash Counts, Transportation Research Record: Journal of the Transportation Research Board, 10.1177/0361198118782797, 2672, 38, (105-115), (2018).
  • Bayesian bootstrap inference for the receiver operating characteristic surface, Stat, 10.1002/sta4.211, 7, 1, (2018).
  • Informativeness of diagnostic marker values and the impact of data grouping, Computational Statistics & Data Analysis, 10.1016/j.csda.2017.07.008, 117, (76-89), (2018).
  • Bayesian nonparametric inference for the three-class Youden index and its associated optimal cutoff points, Statistical Methods in Medical Research, 10.1177/0962280217742538, 27, 3, (689-700), (2017).
  • STARD-BLCM: Standards for the Reporting of Diagnostic accuracy studies that use Bayesian Latent Class Models, Preventive Veterinary Medicine, 10.1016/j.prevetmed.2017.01.006, 138, (37-47), (2017).
  • ROC curves and nonrandom data, Pattern Recognition Letters, 10.1016/j.patrec.2016.11.015, 85, (35-41), (2017).
  • undefined, 2017 International Conference on Advanced Technologies for Communications (ATC), 10.1109/ATC.2017.8167623, (229-234), (2017).
  • Nonparametric Bayesian covariate‐adjusted estimation of the Youden index, Biometrics, 10.1111/biom.12686, 73, 4, (1279-1288), (2017).
  • Minimum distance estimation of the binormal ROC curve, Statistical Papers, 10.1007/s00362-017-0915-7, (2017).
  • Bayesian reclassification statistics for assessing improvements in diagnostic accuracy, Statistics in Medicine, 10.1002/sim.6899, 35, 15, (2574-2592), (2016).
  • Optimal ROC-Based Classification and Performance Analysis under Bayesian Uncertainty Models, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 10.1109/TCBB.2015.2465966, 13, 4, (719-729), (2016).
  • Bayesian modeling and inference for diagnostic accuracy and probability of disease based on multiple diagnostic biomarkers with and without a perfect reference standard, Statistics in Medicine, 10.1002/sim.6745, 35, 6, (859-876), (2015).
  • A unified Bayesian semiparametric approach to assess discrimination ability in survival analysis, Biometrics, 10.1111/biom.12453, 72, 2, (554-562), (2015).
  • Flexible regression models for ROC and risk analysis, with or without a gold standard, Statistics in Medicine, 10.1002/sim.6610, 34, 30, (3997-4015), (2015).
  • An Integrated Bayesian Nonparametric Approach for Stochastic and Variability Orders in ROC Curve Estimation: An Application to Endometriosis Diagnosis, Journal of the American Statistical Association, 10.1080/01621459.2015.1023806, 110, 511, (923-934), (2015).
  • Bayesian Nonparametric Approaches for ROC Curve Inference, Nonparametric Bayesian Inference in Biostatistics, 10.1007/978-3-319-19518-6, (327-344), (2015).
  • Statistical Evaluation of Medical Diagnostic Tests, Wiley StatsRef: Statistics Reference Online, 10.1002/9781118445112, (1-13), (2014).
  • Bayesian semiparametric estimation of covariate-dependent ROC curves, Biostatistics, 10.1093/biostatistics/kxt044, 15, 2, (353-369), (2013).
  • undefined, 2013 IEEE Conference on Computer Vision and Pattern Recognition, 10.1109/CVPR.2013.419, (3262-3269), (2013).
  • Bayesian mixture models for partially verified data: Age- and stage-specific discriminatory power of an antibody ELISA for paratuberculosis, Preventive Veterinary Medicine, 10.1016/j.prevetmed.2013.05.006, 111, 3-4, (200-205), (2013).
  • Robust Medical Test Evaluation Using Flexible Bayesian Semiparametric Regression Models, Epidemiology Research International, 10.1155/2013/131232, 2013, (1-8), (2013).
  • Bayesian spatial modeling of HIV mortality via zero‐inflated Poisson models, Statistics in Medicine, 10.1002/sim.5457, 32, 2, (267-281), (2012).
  • An application of Bayesian growth mixture modelling to estimate infection incidences from repeated serological tests, Statistical Modelling: An International Journal, 10.1177/1471082X12465797, 12, 6, (551-578), (2012).
  • Sample size calculations for ROC studies: parametric robustness and Bayesian nonparametrics, Statistics in Medicine, 10.1002/sim.4396, 31, 2, (131-142), (2011).
  • Modeling continuous diagnostic test data using approximate Dirichlet process distributions, Statistics in Medicine, 10.1002/sim.4320, 30, 21, (2648-2662), (2011).
  • Bayesian ROC Methods, Statistical Evaluation of Diagnostic Performance, 10.1201/b11031-8, (83-100), (2011).
  • Bayesian Methods for Medical Test Accuracy, Diagnostics, 10.3390/diagnostics1010001, 1, 1, (1-35), (2011).
  • Bayesian semiparametric modeling for stochastic precedence, with applications in epidemiology and survival analysis, Lifetime Data Analysis, 10.1007/s10985-010-9164-y, 17, 1, (135-155), (2010).
  • A Bayesian approach to sample size determination for studies designed to evaluate continuous medical tests, Computational Statistics & Data Analysis, 10.1016/j.csda.2009.09.024, 54, 2, (298-307), (2010).
  • Bayesian Estimation of the Probability of Asbestos Exposure from Lung Fiber Counts, Biometrics, 10.1111/j.1541-0420.2009.01279.x, 66, 2, (603-612), (2009).
  • Multivariate mixtures of Polya trees for modeling ROC data, Statistical Modelling: An International Journal, 10.1177/1471082X0700800106, 8, 1, (81-96), (2008).
  • Bayesian semiparametric ROC curve estimation and disease diagnosis, Statistics in Medicine, 10.1002/sim.3250, 27, 13, (2474-2496), (2008).
  • Bayesian modelling of tuberculosis clustering from DNA fingerprint data, Statistics in Medicine, 10.1002/sim.2899, 27, 1, (140-156), (2007).
  • Flexible random‐effects models using Bayesian semi‐parametric models: applications to institutional comparisons, Statistics in Medicine, 10.1002/sim.2666, 26, 9, (2088-2112), (2006).

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