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Communication

Controlled Delivery of DNA Origami on Patterned Surfaces*

Aren E. Gerdon

Department of Physics and Chemistry Emmanuel College Boston, MA 02115 (USA)

These authors contributed equally to this work.Search for more papers by this author
Seung Soo Oh

Materials Department University of California Santa Barbara, CA 93106–5070 (USA)

These authors contributed equally to this work.Search for more papers by this author
Kuangwen Hsieh

Department of Mechanical Engineering University of California Santa Barbara, CA 93106–5070 (USA)

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Yonggang Ke

Department of Chemistry and Biochemistry and the Biodesign Institute Arizona State University Tempe, AZ 85287 (USA)

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Hao Yan

Corresponding Author

E-mail address:hao.yan@asu.edu

Department of Chemistry and Biochemistry and the Biodesign Institute Arizona State University Tempe, AZ 85287 (USA)

Materials Department University of California Santa Barbara, CA 93106–5070 (USA).
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H. Tom Soh

Corresponding Author

E-mail address:tsoh@engr.ucsb.edu

Materials Department University of California Santa Barbara, CA 93106–5070 (USA)

Department of Mechanical Engineering University of California Santa Barbara, CA 93106–5070 (USA)

Materials Department University of California Santa Barbara, CA 93106–5070 (USA).
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First published: 26 August 2009
Cited by: 56
*

A.E.G. thanks Jonas Perez of Vanderbilt University for helpful discussions on nanoparticle functionalization, and Bill Mitchell of UCSB Nanofabrication Facility for his assistance in electron beam lithography. H.T.S. is grateful for financial support from ONR, NIH, and ARO Institute for Collaborative Biotechnologies (DAAD1903D004). H.Y. thanks the funding support of NSF, ONR, AOR, AFOSR, and NIH. All nanofabrication was carried out at the NSF‐supported Nanofabrication Facility at UC Santa Barbara.

Abstract

DNA origami structures are selectively immobilized onto lithographically patterned features with nanometer‐scale precision, and these pre‐positioned origami scaffolds are subsequently utilized as a template to deterministically deliver gold nanoparticles to specific locations within the origami.

Number of times cited: 56

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