Volume 1, Issue 1‐2

Indices of multilocus linkage disequilibrium

Paul‐Michael Agapow

Department of Biology, Imperial College, Silwood Park, Ascot, Berkshire, SL5 7PY, UK

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Austin Burt

Department of Biology, Imperial College, Silwood Park, Ascot, Berkshire, SL5 7PY, UK

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First published: 11 April 2005
Citations: 680
Paul‐Michael Agapow. Fax: + 44 (0) 207 594 2339; E‐mail: p.agapow@ic.ac.uk

Abstract

Linkage disequilibrium is an ubiquitous biological phenomenon. However a common metric for disequilibrium – the index of association or IA– is dependent on sample size. In this paper we present a modification of IA that removes this dependency. This method has been implemented in a software package.

Number of times cited according to CrossRef: 680

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