Volume 55, Issue 2

Bayesian Analysis and Model Selection for Interval‐Censored Survival Data

Debajyoti Sinha

Department of Mathematics, University of New Hampshire, Durham, New Hampshire 03824‐3591, U.S.A. email:sinha@purabi.unh.edu

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Ming‐Hui Chen

Department of Mathematical Sciences, Worcester Polytechnic Institute, Worcester, Massachusetts 01609‐2276, U.S.A.

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Sujit K. Ghosh

Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695‐8203, U.S.A.

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First published: 26 May 2004
Citations: 46

Abstract

Summary. Interval‐censored data occur in survival analysis when the survival time of each patient is only known to be within an interval and these censoring intervals differ from patient to patient. For such data, we present some Bayesian discretized semiparametric models, incorporating proportional and nonproportional hazards structures, along with associated statistical analyses and tools for model selection using sampling‐based methods. The scope of these methodologies is illustrated through a reanalysis of a breast cancer data set (Finkelstein, 1986, Biometrics42, 845–854) to test whether the effect of covariate on survival changes over time.

Number of times cited according to CrossRef: 46

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