Volume 33, Issue 1

The impact of caffeine on mood, cognitive function, performance and hydration: a review of benefits and risks

C. H. S. Ruxton

Nutrition Communications, Cupar, UK

Search for more papers by this author
First published: 13 February 2008
Citations: 73
Dr Carrie H. S. Ruxton, Freelance Dietitian, 6 Front Lebanon, Cupar KY15 4EA, UK.
E‐mail: carrie@nutrition‐communications.com

Abstract

Summary  The reputed benefits of moderate caffeine consumption include improvements in physical endurance, cognitive function, particularly alertness and vigilance, mood and perception of fatigue. In contrast, there are concerns that excessive intakes increase the risks of dehydration, anxiety, headache and sleep disturbances. This paper is a review of double‐blind, placebo‐controlled trials published over the past 15 years to establish what range of caffeine consumption would maximise benefits and minimise risks for cognitive function, mood, physical performance and hydration. Of the 41 human studies meeting the inclusion criteria, the majority reported benefits associated with low to moderate caffeine intakes (37.5 to 450 mg per day). The available studies on hydration found that caffeine intakes up to 400 mg per day did not produce dehydration, even in subjects undergoing exercise testing. It was concluded that the range of caffeine intake that appeared to maximise benefit and minimise risk is 38 to 400 mg per day, equating to 1 to 8 cups of tea per day, or 0.3 to 4 cups of brewed coffee per day. The limitations of the current evidence base are discussed.

Number of times cited according to CrossRef: 73

  • Effects of Caffeine on Auditory- and Vestibular-Evoked Potentials in Healthy Individuals: A Double-Blind Placebo-Controlled Study, Journal of Audiology and Otology, 10.7874/jao.2019.00227, 24, 1, (10-16), (2020).
  • Sleep hygiene in shift workers: A systematic literature review, Sleep Medicine Reviews, 10.1016/j.smrv.2020.101336, (101336), (2020).
  • Water, Informatorium voor Voeding en Diëtetiek – Supplement 105 – augustus 2020, 10.1007/978-90-368-2537-5, (107-127), (2020).
  • Effect of brewing conditions using a single‐serve coffee maker on black tea (Lapsang Souchong) quality, Food Science & Nutrition, 10.1002/fsn3.1735, 8, 8, (4379-4387), (2020).
  • Beneficial Effects of Dark Chocolate for Episodic Memory in Healthy Young Adults: A Parallel-Groups Acute Intervention with a White Chocolate Control, Nutrients, 10.3390/nu12020483, 12, 2, (483), (2020).
  • Caffeine-Containing, Adaptogenic-Rich Drink Modulates the Effects of Caffeine on Mental Performance and Cognitive Parameters: A Double-Blinded, Placebo-Controlled, Randomized Trial, Nutrients, 10.3390/nu12071922, 12, 7, (1922), (2020).
  • Recent Caffeine Drinking Associates with Cognitive Function in the UK Biobank, Nutrients, 10.3390/nu12071969, 12, 7, (1969), (2020).
  • Effects of caffeine intake on the biomechanical properties of the cornea: a placebo-controlled, double-blind, crossover pilot study in low caffeine consumers, Graefe's Archive for Clinical and Experimental Ophthalmology, 10.1007/s00417-020-04835-0, (2020).
  • In Response to Letter to the Editor Regarding: A 10‐Year Study of the Etiopathogenesis of Cysts With a Study of Seromucinous Glands in Vocal Folds, The Laryngoscope, 10.1002/lary.28375, 130, 6, (E399-E399), (2019).
  • Nutrition, The Art and Science of Physician Wellbeing, 10.1007/978-3-319-42135-3, (235-254), (2019).
  • Coffee, Caffeine and Cognition: a Benefit or Disadvantage?, Letters in Drug Design & Discovery, 10.2174/1570180816666190620142158, 16, 10, (1146-1156), (2019).
  • Development of the Functions of the Autobiographical Memory in Shikohin Inventory嗜好品による自伝的記憶の機能尺度の開発, The Japanese Journal of Personality, 10.2132/personality.28.1.9, (2019).
  • Diets and Diet Therapy: Diet Supplements for Exercise, Encyclopedia of Food Security and Sustainability, 10.1016/B978-0-08-100596-5.21957-4, (161-170), (2019).
  • More than just caffeine: psychopharmacology of methylxanthine interactions with plant-derived phytochemicals, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 10.1016/j.pnpbp.2018.09.005, 89, (263-274), (2019).
  • Effects of acute caffeine consumption following sleep loss on cognitive, physical, occupational and driving performance: A systematic review and meta-analysis, Neuroscience & Biobehavioral Reviews, 10.1016/j.neubiorev.2019.12.008, (2019).
  • The acute effects of decaffeinated versus caffeinated coffee on reaction time, mood and skeletal muscle strength, Journal of Basic and Clinical Physiology and Pharmacology, 10.1515/jbcpp-2018-0119, 0, 0, (2019).
  • Cognitive performance in relation to hydration status and water intake among older adults, NHANES 2011–2014, European Journal of Nutrition, 10.1007/s00394-019-02152-9, (2019).
  • Vigilance Decrement and Enhancement Techniques: A Review, Brain Sciences, 10.3390/brainsci9080178, 9, 8, (178), (2019).
  • Caffeine improves text reading and global perception, Journal of Psychopharmacology, 10.1177/0269881119878178, (026988111987817), (2019).
  • Caffeine and Exercise: What Next?, Sports Medicine, 10.1007/s40279-019-01101-0, (2019).
  • The Consumption of Breakfast, Fish and/or Caffeine does not Predict Study Progress in Adult Distance Education, International Journal for Vitamin and Nutrition Research, 10.1024/0300-9831/a000278, (1-9), (2019).
  • Emotional Memory in Oral Contraceptive Users: Negative Stimuli Are More Forgettable, Psychological Reports, 10.1177/0033294119856554, (003329411985655), (2019).
  • Caffeine Content and Perceived Sensory Characteristics of Pod Coffee: Effects on Mood and Cognitive Performance, Current Research in Nutrition and Food Science Journal, 10.12944/CRNFSJ.6.2.08, 6, 2, (329-345), (2018).
  • The characteristics and functions of involuntary autobiographical memory cued by consuming “shikohin”嗜好品摂取時に無意図的に想起される自伝的記憶の特性と機能, The Japanese Journal of Cognitive Psychology, 10.5265/jcogpsy.15.39, 15, 2, (39-51), (2018).
  • Caffeine in teas: levels, transference to infusion and estimated intake, Food Science and Technology, 10.1590/1678-457x.12217, 38, 4, (661-666), (2018).
  • Consumir la obra de terra. Los orígenes de la cerámica valenciana por el lado de la demanda (1283-1349), Hispania, 10.3989/hispania.2018.003, 78, 258, (69), (2018).
  • Pharmacological potential of methylxanthines: Retrospective analysis and future expectations, Critical Reviews in Food Science and Nutrition, 10.1080/10408398.2018.1461607, (1-29), (2018).
  • Partitioning of caffeine in lipid bilayers reduces membrane fluidity and increases membrane thickness, Physical Chemistry Chemical Physics, 10.1039/C6CP08104E, 19, 10, (7101-7111), (2017).
  • Hydroxycinnamic Acids: Natural Sources, Biosynthesis, Possible Biological Activities, and Roles in Islamic Medicine, , 10.1016/B978-0-444-64068-0.00008-5, (269-292), (2017).
  • Effects of Camellia Sinensis Extract on Passive Avoidance Learning and Hippocampal Neurogenesis in Rats, Neurophysiology, 10.1007/s11062-017-9642-x, 49, 2, (135-142), (2017).
  • Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children, Food and Chemical Toxicology, 10.1016/j.fct.2017.04.002, 109, (585-648), (2017).
  • A review of caffeine use as a risk or protective factor for womenʼs health and pregnancy, Current Opinion in Psychiatry, 10.1097/YCO.0000000000000333, 30, 4, (253-259), (2017).
  • Methylxanthine Content in Commonly Consumed Foods in Spain and Determination of Its Intake during Consumption, Foods, 10.3390/foods6120109, 6, 12, (109), (2017).
  • Coffee and Caffeine Intake among Students of the Brazilian Northeast, Food and Nutrition Sciences, 10.4236/fns.2016.71004, 07, 01, (30-36), (2016).
  • Running on empty: a review of nutrition and physicians' well-being, Postgraduate Medical Journal, 10.1136/postgradmedj-2016-134131, 92, 1090, (478-481), (2016).
  • Physical Activity, Sleep, and Nutrition Do Not Predict Cognitive Performance in Young and Middle-Aged Adults, Frontiers in Psychology, 10.3389/fpsyg.2016.00642, 7, (2016).
  • Military-specific application of nutritional supplements: a brief overview, F1000Research, 10.12688/f1000research.6187.1, 4, (61), (2015).
  • The Effects of Caffeine Use on Driving Safety Among Truck Drivers Who Are Habitual Caffeine Users, Workplace Health & Safety, 10.1177/2165079915579561, 63, 8, (333-341), (2015).
  • The effect of self‐regulated caffeine use on cognition in young adults, Human Psychopharmacology: Clinical and Experimental, 10.1002/hup.2464, 30, 2, (123-130), (2015).
  • The psychological effects of taking in “Shikohin”: A cross-sectional exploratory study, The Japanese journal of psychology, 10.4992/jjpsy.86.14321, 86, 4, (354-360), (2015).
  • Investigating the effects of tea, water and a positive affect induction on mood and creativity, Food Quality and Preference, 10.1016/j.foodqual.2014.06.016, 39, (56-61), (2015).
  • Is tea a healthy source of hydration?, Nutrition Bulletin, 10.1111/nbu.12150, 40, 3, (166-176), (2015).
  • Modulation of 3′,5′-cyclic AMP homeostasis in human platelets by coffee and individual coffee constituents, British Journal of Nutrition, 10.1017/S0007114514002232, 112, 09, (1427-1437), (2014).
  • Criteria for validation and selection of cognitive tests for investigating the effects of foods and nutrients, Nutrition Reviews, 10.1111/nure.12094, 72, 3, (162-179), (2014).
  • The effects of caffeine on option generation and subsequent choice, Psychopharmacology, 10.1007/s00213-014-3506-5, 231, 18, (3719-3727), (2014).
  • Habitual Coffee Consumption Enhances Attention and Vigilance in Hemodialysis Patients, BioMed Research International, 10.1155/2014/707460, 2014, (1-7), (2014).
  • Fluid, Electrolytes and Hydration Needs of Masters Athletes, Nutrition and Performance in Masters Athletes, 10.1201/b17541, (171-182), (2014).
  • The effect of caffeine on spontaneous pupillary oscillations, Ophthalmic and Physiological Optics, 10.1111/opo.12094, 34, 1, (73-81), (2013).
  • Hydration and health, Nutrition Bulletin, 10.1111/nbu.12039, 39, 1, (4-8), (2013).
  • The suitability of caffeinated drinks for children: a systematic review of randomised controlled trials, observational studies and expert panel guidelines, Journal of Human Nutrition and Dietetics, 10.1111/jhn.12172, 27, 4, (342-357), (2013).
  • Caffeine and chlorogenic acids intake from coffee brew: influence of roasting degree and brewing procedure, International Journal of Food Science & Technology, 10.1111/ijfs.12361, 49, 3, (747-752), (2013).
  • Water, Informatorium voor Voeding en Diëtetiek, 10.1007/978-90-368-0510-0, (339-361), (2013).
  • Brain imaging and human nutrition: which measures to use in intervention studies?, British Journal of Nutrition, 10.1017/S0007114513001384, 110, S1, (S1-S30), (2013).
  • Effects of chocolate on cognitive function and mood: a systematic review, Nutrition Reviews, 10.1111/nure.12065, 71, 10, (665-681), (2013).
  • What are the health implications associated with the consumption of energy drinks? A systematic review, Nutrition Reviews, 10.1111/nure.12005, 71, 3, (135-148), (2013).
  • Acute effects of tea consumption on attention and mood, The American Journal of Clinical Nutrition, 10.3945/ajcn.113.058248, 98, 6, (1700S-1708S), (2013).
  • Psychopharmacology of theobromine in healthy volunteers, Psychopharmacology, 10.1007/s00213-013-3021-0, 228, 1, (109-118), (2013).
  • The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness, Nutritional Neuroscience, 10.1179/147683010X12611460764840, 13, 6, (283-290), (2013).
  • Caffeine as an attention enhancer: reviewing existing assumptions, Psychopharmacology, 10.1007/s00213-012-2917-4, 225, 2, (251-274), (2012).
  • Additional Positive Impacts on Health, Coffee, 10.1002/9781119949893, (233-241), (2012).
  • Tisane: nutraceutique ou pharmaceutique ?, Phytothérapie, 10.1007/s10298-012-0714-1, 10, 4, (245-250), (2012).
  • The Effects of Dietary Caffeine Use and Abstention on Blood Oxygen Level-Dependent Activation and Cerebral Blood Flow, Journal of Caffeine Research, 10.1089/jcr.2011.0027, 2, 1, (15-22), (2012).
  • Is black tea consumption associated with a lower risk of cardiovascular disease and type 2 diabetes?, Nutrition Bulletin, 10.1111/j.1467-3010.2011.01937.x, 37, 1, (4-15), (2011).
  • Black tea improves attention and self-reported alertness, Appetite, 10.1016/j.appet.2010.12.011, 56, 2, (235-240), (2011).
  • Black tea is not significantly different from water in the maintenance of normal hydration in human subjects: results from a randomised controlled trial, British Journal of Nutrition, 10.1017/S0007114511000456, 106, 4, (588-595), (2011).
  • Mission impossible? Regulatory and enforcement issues to ensure safety of dietary supplements, Food and Chemical Toxicology, 10.1016/j.fct.2010.11.014, 49, 2, (393-402), (2011).
  • Hydration and health: a review, Nutrition Bulletin, 10.1111/j.1467-3010.2009.01795.x, 35, 1, (3-25), (2010).
  • A randomised cross-over trial to evaluate the impact of tea on measures of hydration, Proceedings of the Nutrition Society, 10.1017/S0029665110002491, 69, OCE5, (2010).
  • A comparison of the effects of caffeine following abstinence and normal caffeine use, Psychopharmacology, 10.1007/s00213-009-1668-3, 207, 3, (423-431), (2009).
  • The health effects of black tea and flavonoids, Nutrition & Food Science, 10.1108/00346650910957546, 39, 3, (283-294), (2009).
  • Black tea and health, Nutrition Bulletin, 10.1111/j.1467-3010.2008.00691.x, 33, 2, (91-101), (2008).
  • BNF: the next chapter, Nutrition Bulletin, 10.1111/j.1467-3010.2007.00678.x, 33, 1, (1-3), (2008).
  • Coffee and tea for health?, Nurse Prescribing, 10.12968/npre.2008.6.8.30762, 6, 8, (334-336), (2008).

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.