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Mind, Brain, and Education

Volume 7, Issue 4
Special Section

Obesity‐Related Hormones in Low‐Income Preschool‐Age Children: Implications for School Readiness

Alison L. Miller

Corresponding Author

Department of Health Behavior and Health Education, School of Public Health, University of Michigan

Center for Human Growth and Development, University of Michigan

Address correspondence to Alison L. Miller, 1415 Washington Heights, SPH 1, Room 3718, University of Michigan, Ann Arbor, MI 48109‐2029; e‐mail:

alimill@umich.edu

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Carey N. Lumeng

Department of Pediatrics and Communicable Diseases, University of Michigan

Department of Molecular and Integrative Physiology, University of Michigan

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Jennifer Delproposto

Department of Pediatrics and Communicable Diseases, University of Michigan

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Brian Florek

Center for Human Growth and Development, University of Michigan

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Kristin Wendorf

Center for Human Growth and Development, University of Michigan

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Julie C. Lumeng

Center for Human Growth and Development, University of Michigan

Department of Pediatrics and Communicable Diseases, University of Michigan

Human Nutrition Program, Department of Environmental Health Sciences, School of Public Health, University of Michigan

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First published: 14 November 2013
https://doi.org/10.1111/mbe.12034
Cited by: 3

ABSTRACT

Mechanisms underlying socioeconomic disparities in school readiness and health outcomes, particularly obesity, among preschool‐aged children are complex and poorly understood. Obesity can induce changes in proteins in the circulation that contribute to the negative impact of obesity on health; such changes may relate to cognitive and emotion regulation skills important for school readiness. We investigated obesity‐related hormones, body mass index (BMI), and school readiness in a pilot study of low‐income preschoolers attending Head Start (participating in a larger parent study). We found that the adipokine leptin was related to preschoolers' BMI z‐score, the appetite‐regulating hormones ghrelin and glucagon‐like peptide 1 (GLP‐1), and pro‐inflammatory cytokines typically associated with early life stress; and that some of these obesity‐related biomarkers were in turn related to emotion regulation. Future work should evaluate how obesity may affect multiple domains of development, and consider modeling common physiological pathways related to stress, health, and school readiness.

Number of times cited: 3

  • Carolyn Sutter, Lenna L. Ontai, Mical K. Shilts, Louise Lanoue, Lindsay H. Allen and Marilyn S. Townsend, Associations Between School Readiness and Obesity‐ and Inflammation‐Related Biomarkers in Low‐Income Preschoolers Within the Healthy Kids Study, Mind, Brain, and Education, 12, 1, (28-38), (2018).
    Wiley Online Library
  • Ana Cristina R. Camargos, Vanessa A. Mendonça, Katherine S.C. Oliveira, Camila Alves de Andrade, Hércules Ribeiro Leite, Sueli Ferreira da Fonseca, Erica Leandro Marciano Vieira, Antônio Lúcio Teixeira Júnior and Ana Cristina Rodrigues Lacerda, Association between obesity-related biomarkers and cognitive and motor development in infants, Behavioural Brain Research, 325, (12), (2017).
    Crossref
  • Christy Y.Y. Leung, Julie C. Lumeng, Niko A. Kaciroti, Yu Pu Chen, Katherine Rosenblum and Alison L. Miller, Surgency and negative affectivity, but not effortful control, are uniquely associated with obesogenic eating behaviors among low-income preschoolers, Appetite, 78, (139), (2014).
    Crossref