Drug Targeting: Organ-Specific Strategies, Volume 12
Editor(s):
- Dr. Grietje Molema
- Prof. Dr. Dirk K. F. Meijer
First published:12 July 2001
Print ISBN:9783527299898 |Online ISBN:9783527600069 |DOI:10.1002/352760006X
Copyright © 2001 Wiley‐VCH Verlag GmbH
Book Series:Methods and Principles in Medicinal Chemistry
About this book
How are medicines transported intact through the body to their specific target sites
without triggering side effects? The answer is "Drug Targeting".
This thoroughly application-oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on the practical aspect and successful application of the method in question, although a glance at what the future holds is also included. A volume that every pharmaceutically oriented research group should own.
This thoroughly application-oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on the practical aspect and successful application of the method in question, although a glance at what the future holds is also included. A volume that every pharmaceutically oriented research group should own.
Reviews
"there have been few books that set out to give an overview of the state of the art
in the field. This excellent text fills that gap and is a must for the bookshelves
of academic and industrial research scientists...The book is excellent and well researched.
... A welcome addition to the library!" Angewandte Chemie International Edition Vol.
41, No. 7 April 2002
Author Bios
Grietje Molema and Dirk K. F. Meijer are the authors of Drug Targeting: Organ-Specific Strategies, published by Wiley.
Table of Contents
CHAPTER 6
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A Practical Approach in the Design of Colon‐specific Drug Delivery Systems (Pages: 157-170)
CHAPTER 7
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Vascular Endothelium in Inflamed Tissue as a Target for Site Selective Delivery of Drugs (Pages: 171-197)
CHAPTER 10
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Phage Display Technology for Target Discovery in Drug Delivery Research (Pages: 255-273)
CHAPTER 11
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