Efficient Replication Bypass of Size‐Expanded DNA Base Pairs in Bacterial Cells - Delaney - 2009 - Angewandte Chemie - Wiley Online Library

Zuschrift

Efficient Replication Bypass of Size‐Expanded DNA Base Pairs in Bacterial Cells*

James C. Delaney Dr.

Departments of Chemistry and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA)

Search for more papers by this author

Jianmin Gao Dr.

Department of Chemistry, Stanford University, Stanford, CA 94305 (USA)

Search for more papers by this author

Haibo Liu Dr.

Department of Chemistry, Stanford University, Stanford, CA 94305 (USA)

Search for more papers by this author

Nidhi Shrivastav

Departments of Chemistry and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA)

Search for more papers by this author

John M. Essigmann Prof. Dr.

E-mail address:jessig@mit.edu

Departments of Chemistry and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA)

Search for more papers by this author

Eric T. Kool Prof. Dr.

E-mail address:kool@stanford.edu

Department of Chemistry, Stanford University, Stanford, CA 94305 (USA)

Search for more papers by this author

James C. Delaney Dr.

Departments of Chemistry and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA)

Search for more papers by this author

Jianmin Gao Dr.

Department of Chemistry, Stanford University, Stanford, CA 94305 (USA)

Search for more papers by this author

Haibo Liu Dr.

Department of Chemistry, Stanford University, Stanford, CA 94305 (USA)

Search for more papers by this author

Nidhi Shrivastav

Departments of Chemistry and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA)

Search for more papers by this author

John M. Essigmann Prof. Dr.

E-mail address:jessig@mit.edu

Departments of Chemistry and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (USA)

Search for more papers by this author

Eric T. Kool Prof. Dr.

E-mail address:kool@stanford.edu

Department of Chemistry, Stanford University, Stanford, CA 94305 (USA)

Search for more papers by this author

First published: 14 May 2009

https://doi.org/10.1002/ange.200805683

Cited by: 7

We thank the U.S. National Institutes of Health (CA80024 to J.M.E. and GM63587 to E.T.K.) for support. J.G. and H.L. acknowledge Stanford Graduate Fellowships.

Abstract

Groß, aber nicht zu groß: Vergrößerte DNA‐Basen (xDNA) können natürliche DNA‐Sequenzen in der Replizierung kodieren. In‐vitro‐Experimente mit einer DNA‐Polymerase belegen den Nucleotideinbau mit korrekter Paarung gegenüberliegend zu xDNA‐Basen, und bei In‐vivo‐Replizierungen mit E. coli führten die beiden xDNA‐Basen xA und xC (siehe Bild) zum Einbau der korrekten Partner.

Citing Literature

Number of times cited: 7

Amit M. Jabgunde, Faten Jaziri, Omprakash Bande, Matheus Froeyen, Mikhail Abramov, Hoai Nguyen, Guy Schepers, Eveline Lescrinier, Vitor B. Pinheiro, Valérie Pezo, Philippe Marlière and Piet Herdewijn, Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo, Chemistry – A European Journal, 24, 48, (12695-12707), (2018).
Wiley Online Library
Rania Abu El Asrar, Lia Margamuljana, Mikhail Abramov, Omprakash Bande, Stefano Agnello, Miyeon Jang and Piet Herdewijn, Enzymatic Incorporation of Modified Purine Nucleotides in DNA, ChemBioChem, 18, 24, (2408-2415), (2017).
Wiley Online Library
Elena Eremeeva, Michail Abramov, Lia Margamuljana and Piet Herdewijn, Base‐Modified Nucleic Acids as a Powerful Tool for Synthetic Biology and Biotechnology, Chemistry – A European Journal, 23, 40, (9560-9576), (2017).
Wiley Online Library
Elena Eremeeva, Michail Abramov, Lia Margamuljana, Jef Rozenski, Valerie Pezo, Philippe Marlière and Piet Herdewijn, Chemical Morphing of DNA Containing Four Noncanonical Bases, Angewandte Chemie International Edition, 55, 26, (7515-7519), (2016).
Wiley Online Library
Elena Eremeeva, Michail Abramov, Lia Margamuljana, Jef Rozenski, Valerie Pezo, Philippe Marlière and Piet Herdewijn, Chemical Morphing of DNA Containing Four Noncanonical Bases, Angewandte Chemie, 128, 26, (7641-7645), (2016).
Wiley Online Library
Malte Winnacker and Eric T. Kool, Künstliche genetische Systeme bestehend aus vergrößerten Basenpaaren, Angewandte Chemie, 125, 48, (12728-12739), (2013).
Wiley Online Library
Malte Winnacker and Eric T. Kool, Artificial Genetic Sets Composed of Size‐Expanded Base Pairs, Angewandte Chemie International Edition, 52, 48, (12498-12508), (2013).
Wiley Online Library