PROTEINS: Structure, Function, and Bioinformatics is an international protein science journal publishing experimental and analytic research in all areas of the field, encompassing protein structure, function, computation, genetics, and design.

We encourage reports that present new experimental or computational approaches for interpreting and understanding data. PROTEINS : Structure, Function, and Bioinformatics is read globally by researchers in a variety of fields – from biochemists to crystallographers.

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About This Journal

PROTEINS : Structure, Function, and Bioinformatics publishes original reports of significant experimental and analytic research in all areas of protein research: structure, function, computation, genetics, and design.

The journal encourages reports that present new experimental or computational approaches for interpreting and understanding data from:

  • Biophysical chemistry
  • Structural studies of proteins and macromolecular assemblies
  • Alterations of protein structure and function engineered through techniques of molecular biology 
  • Genetics
  • Functional analyses under physiologic conditions
  • Interactions of proteins with receptors, nucleic acids, or other specific ligands or substrates

Read the full Aims and Scope here.

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Articles

RESEARCH ARTICLE

Prediction of interactions between cell surface proteins by machine learning

Zhaoqian Su, Brian Griffin, Scott Emmons, Yinghao Wu, 
  •  5 December 2023
RESEARCH ARTICLE

Structural implications of amyloidogenic rare variants Ser282Leu and Gln356Arg identified in h-BRCA1

Neha Mishra, Suchita Dubey, Anchala Kumari, Mudassar Ali Khan, Ekaterina S. Kuligina, Elena V. Preobrazhenskaya, Alexandr A. Romanko, Lumbini R. Yadav, Rajiv Sarin, Evgeny N. Imyanitov, Ashok K. Varma, 
  •  1 December 2023
RESEARCH ARTICLE

The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b5 core to form a helical motif that is of ancient origin

David R. Benson, Bin Deng, Maithri M. Kashipathy, Scott Lovell, Kevin P. Battaile, Anne Cooper, Philip Gao, Aron W. Fenton, Hao Zhu, 
  •  1 December 2023
ISSUE INFORMATION ‐ COVER IMAGE
free access

Cover Image, Volume 91, Issue 12

Rhiju Das, Rachael C. Kretsch, Adam J. Simpkin, Thomas Mulvaney, Phillip Pham, Ramya Rangan, Fan Bu, Ronan M. Keegan, Maya Topf, Daniel J. Rigden, Zhichao Miao, Eric Westhof, 
  •  C4-C4
  •  23 November 2023

Graphical Abstract

Description unavailable

Reverse Cover: The cover image is based on the Research Article Assessment of three-dimensional RNA structure prediction in CASP15 by Rhiju Das and Rachael C. Kretsch et al., https://doi.org/10.1002/prot.26602.

REVIEW ARTICLE
Open access

Biotin protein ligase as you like it: Either extraordinarily specific or promiscuous protein biotinylation

John E. Cronan, 
  •  23 November 2023
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