Editor-in-Chief: Prof. Christoph Plass
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Journal Overview
The International Journal of Cancer (IJC) is the official journal of the Union for International Cancer Control (UICC). IJC has a global readership and receives over 3,000 submissions a year under a broad scope of topics relevant to experimental and clinical cancer research. We invite and encourage original Research Articles and Short Reports.
Articles
Extracellular vesicles secreted by triple negative breast cancer stem cells trigger pre-metastatic niche remodeling and metastatic growth in the lungs
-  27 January 2023
HPV hijacks enhancers to activate oncogenes in head and neck squamous cell carcinoma cells
-  24 January 2023
Managing an Extension of Screening Intervals: Avoiding Boom and Bust in Health Care Workloads
-  24 January 2023
Molnupiravir is effective in patients with haematological malignancies
-  24 January 2023
Lipid raft protein flotillin-1 is important for the interaction between SOS1 and H-Ras/K-Ras, leading to Ras activation
-  24 January 2023
The following is a list of the most accessed articles in 2018.
Cancer statistics for the year 2020: An overview
-  778-789
-  5 April 2021
Abstract
What's new?
As part of the latest International Agency for Research on Cancer (IARC) GLOBOCAN cancer statistics update, here the authors provide a comprehensive description of the data sources and methods used to compute the global incidence and mortality estimates for 38 cancers corresponding to the year 2020. The reported uncertainty intervals incorporate the major sources of error that may contribute to the uncertainty of these estimations. In addition to providing a global snapshot of the cancer burden in 2020, the estimates presented here can support the planning and prioritization of cancer control efforts at the global and national levels.
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
-  E359-E386
-  13 September 2014
Abstract
What's new?
In this report, we present the most recent cancer incidence and mortality statistics (for 2012) for the major cancers in 20 regions of the world. Details of the data sources and methods used in GLOBOCAN to compile the estimates at the national level are provided, and we introduce a novel alphanumeric scoring system to give a broad indication of the robustness of the estimation within each country. A global snapshot of the patterns by cancer site brings focus to the need for regional prioritisation of cancer control efforts, as well as the ongoing efforts to improve the limited surveillance systems in many low and middle income countries.
Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods
-  1941-1953
-  23 October 2018
Abstract
What's new?
The GLOBOCAN database, compiled by the International Agency for Research on Cancer (IARC), is updated regularly, providing timely estimates on national cancer incidence and mortality. Here, the authors, associated with the IARC, describe the data sources and methods used to compute global cancer incidence and mortality estimates for 38 specific cancers detailed in GLOBOCAN 2018. The authors further describe novel uncertainty intervals, newly derived from a method incorporating covariates that contribute to uncertainty in cancer estimation. Uncertainty intervals are presented alongside overall estimates, which indicate that 18.1 million new cancer cases and 9.6 million cancer deaths occurred globally in 2018.
A brief history of cancer: Age-old milestones underlying our current knowledge database
-  2022-2036
-  11 August 2014
Alcohol metabolism genes and risks of site-specific cancers in Chinese adults: An 11-year prospective study
-  1627-1639
-  20 January 2022
Graphical Abstract

What's new?
Alcohol consumption has been increasing among men in China, and is a major contributor to the total cancer burden. Two genetic variants that alter alcohol metabolism are associated with esophageal cancer risk in East Asians. Do these variants also play a role in other cancers, or influence the effect of alcohol on cancer risk? In this large Chinese study, the authors found that certain genotypes were associated with reduced upper aero-digestive tract cancer risk, and that one of the variants may exacerbate the effects of alcohol on several cancers.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
- International Journal of Cancer
-  E359-E386
-  13 September 2014
Abstract
What's new?
In this report, we present the most recent cancer incidence and mortality statistics (for 2012) for the major cancers in 20 regions of the world. Details of the data sources and methods used in GLOBOCAN to compile the estimates at the national level are provided, and we introduce a novel alphanumeric scoring system to give a broad indication of the robustness of the estimation within each country. A global snapshot of the patterns by cancer site brings focus to the need for regional prioritisation of cancer control efforts, as well as the ongoing efforts to improve the limited surveillance systems in many low and middle income countries.
Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods
- International Journal of Cancer
-  1941-1953
-  23 October 2018
Abstract
What's new?
The GLOBOCAN database, compiled by the International Agency for Research on Cancer (IARC), is updated regularly, providing timely estimates on national cancer incidence and mortality. Here, the authors, associated with the IARC, describe the data sources and methods used to compute global cancer incidence and mortality estimates for 38 specific cancers detailed in GLOBOCAN 2018. The authors further describe novel uncertainty intervals, newly derived from a method incorporating covariates that contribute to uncertainty in cancer estimation. Uncertainty intervals are presented alongside overall estimates, which indicate that 18.1 million new cancer cases and 9.6 million cancer deaths occurred globally in 2018.