Edited By: Robert Heath
The Journal of Cellular Physiology examines eukaryotic cell biology and physiology. Our journal focuses on articles that adopt a molecular mechanistic approach to investigate cell structure and function using cellular, biochemical, molecular, genetic, genomic, proteomic and bioinformatic approaches.
All our articles have a clear hypothesis and present novel and significant findings. We offer free format submission making initial submission easy.
Articles
SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish
-  25 March 2025
Cardiomyocytic FoxP3 Attenuates Expression of β Isoform of Myosin Heavy Chain During Cardiac Hypertrophy and Effects of Triptolide
-  24 March 2025
Graphical Abstract

Cardiomyocytic FoxP3 exerts protective function during cardiac hypertrophy. By suppressing transcription of β-MHC and interfering with the function of NFATc3, FoxP3 downregulates the expression of hypertrophic-related genes (e.g., ANP, BNP, and β-MHC). The bioactive natural product, triptolide, can reverse cardiac hypertrophy by increasing the expression of cardiomyocytic FoxP3.
Daytime-Restricted Feeding Alleviates D-Galactose-Induced Aging in Mice and Regulates the AMPK and mTORC1 Activities
-  11 March 2025
Trophic Factors in Muscle‐Nerve Cross‐Talk Signaling Augment Muscle Fiber and Motor Endplate Development
-  23 February 2025
Comparative Single‐Cell Analysis Reveals Tendon Progenitor Dysfunction by Age‐Associated Oxidative Stress and Its Restoration by Antioxidant Treatments
-  23 February 2025
Role of Metabolic Sensor GPR81/HCAR1 in Diabetic Podocytes: Downregulated Lipolysis Results in the Deterioration of Glomerular Filtration Barrier
-  17 February 2025
Graphical Abstract
Single-Cell Transcriptome Decoding Umbilical Cord-Derived Mesenchymal Stem Cell Heterogeneity Reveals a Unique IL1R1HighPDGFRAHigh Ultroser-G-MSC With Osteogenesis and Chondrogenesis Signatures
-  16 February 2025
Graphical Abstract

The heterogeneity of umbilical cord mesenchymal stem cells (UC-MSCs) caused by different culture systems hampers clinical application. The authors map a comprehensive single-cell transcriptome atlas to decipher the heterogeneity of hUC-MSC in different culture systems, revealing a unique IL1R1highPDGFRAhigh Ultroser-G-MSC subgroups that have better efficacy in the treatment of osteoarthritis (OA), providing a more targeted method for the treatment of OA. (Created with BioRender.com)
Stearoyl‐CoA Desaturase 1 Regulates Metabolism and Inflammation in Mouse Perivascular Adipose Tissue in Response to a High‐Fat Diet
-  12 February 2025
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