Editor-in-Chief: Dr Philippe Vielh
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Announcement
We are pleased to announce two annual Mina Desai Awards for Cytopathology authors, starting from 2022. The Mina Desai Award for Research Excellence recognizes authors of an outstanding paper, while the Mina Desai Early Career Investigator Award recognizes the contribution of authors who are in a training or early career position, or who are within 5 years of appointment to a senior position. Professor Mina Desai is a former Editor of Cytopathology and has made an outstanding contribution to the field of cytology.
For more detailed information on the criteria for each award, please see here.
On the Cover
Articles
Pre‐analytical effects on whole transcriptome and targeted RNA sequencing analysis in cytology: The effects of prolonged time in storage of effusion specimens prior to preservation
- 15 September 2023
Graphical Abstract
Malignant effusions prepared as cytospin slides are viable specimens for RNA sequencing analysis, even when faced with prolonged time in refrigerator storage without preservative solution.
Challenging lesions in cervical cytology: The elusive HSIL
- 14 September 2023
Graphical Abstract
Despite the long and widespread use of the Pap test, cervical cytology remains a diagnostically challenging area in the practice of cytopathology. Given the importance of accurately diagnosing high-grade squamous intraepithelial lesions (HSILs) in particular, this review highlights the diagnostic features of HSIL, explores its morphologic mimics, and describes important morphological clues for differentiation of these lesions.
Case report metastatic SMARCB1 (INI1)‐deficient gastric undifferentiated carcinoma in pleural effusion: A case report and literature review
- 14 September 2023
Graphical Abstract
INI1-deficient gastric undifferentiated carcinoma is a rare tumour that may present as high-grade epithelioid morphology without apparent rhabdoid tumour cells. Syncytial tumour cells may be a crucial clue in such cases, especially in cytological specimens. Cell block and immunocytochemical staining can be valuable tools in achieving an accurate diagnosis.
Metastatic gastrointestinal stromal tumour in pleural fluid 19 years after initial diagnosis
- 12 September 2023
Abstract
Gastrointestinal stromal tumours (GISTs) are rarely encountered in pleural fluid samples. We report a case of GIST metastatic to pleural fluid almost two decades after the original diagnosis. Careful screening by a cytotechnologist, consideration of the clinical history, and judicious use of immunohistochemical stains facilitated the uncommon diagnosis.
The yield of cytology and histology obtained by endoscopic ultrasound‐guided fine needle aspiration and biopsy needles in the diagnosis of pancreatic adenocarcinoma
- 12 September 2023
Graphical Abstract
Adding cytological assessment to EUS-FNB performed for pancreatic solid lesions improved the diagnostic yield.
EUS-guided tissue acquisition using FNB/FNA needles is the main diagnostic tool for pancreatic solid lesion. Obtaining histological specimens by both needles has limited diagnostic yield. It is advocated to perform cytological evaluation to improve the diagnostic yield.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
The presence of a cytopathologist increases the diagnostic accuracy of endoscopic ultrasound‐guided fine needle aspiration cytology for pancreatic adenocarcinoma: a meta‐analysis
- 159-171
- 27 May 2013
Cell blocks in cytopathology: An update
- 505-524
- 28 August 2018
Abstract
With the increasing tendency to utilise minimally invasive procedures, cytology is emerging as a primary modality for tissue diagnosis. Cell blocks are an invaluable adjunct due to their versatility for ancillary testing. This review summarises the latest information on cell block preparatory techniques, their diagnostic utility and role in ancillary testing.
The utility of the Milan System as a risk stratification tool for salivary gland fine needle aspiration cytology specimens
- 91-98
- 10 October 2018
Abstract
The main objective of this study was to assess the diagnostic accuracy of salivary gland fine needle aspirations (FNA) within the framework of the Milan System and evaluate the Milan System for Reporting Salivary Gland Cytopathology as a tool for risk assessment. We document our institutional experience with salivary gland FNAs over an 8-year period, retrospectively applying Milan System categorizations to cytologic diagnoses, comparing pre- and post-operative diagnoses, and determining risks of neoplasm and malignancy.
Touch imprint cytology on endoscopic ultrasound fine‐needle biopsy provides comparable sample quality and diagnostic yield to standard endoscopic ultrasound fine‐needle aspiration specimens in the evaluation of solid pancreatic lesions
- 179-186
- 28 November 2018
Abstract
Cytology and histology present pros and cons in the preoperative evaluation of solid pancreatic lesions, and which one should be preferred is still a matter of debate. The use of the touch imprint cytology on EUS-fine-needle-biopsy specimens allows to combine the benefits by providing cytological and histological samples acquired during the same procedure and with the same needle. In our study sample quality and diagnostic yield of EUS standard cytology and EUS touch imprint cytology were evaluated in patients who underwent EUS-FNA and paired EUS-FNB with rapid-on-site assessment of the same lesion.
Current state of whole slide imaging use in cytopathology: Pros and pitfalls
- 372-378
- 5 February 2020
Abstract
This review summarizes the advantages and the disadvantages of the use of whole slide imaging (WSI) in cytopathology, starting from the cytological specimen to the entire laboratory and istitution. Whole Slide Imaging provides high-quality standardized slides, but there is still a need for validation studies before full adoption for primary diagnosis. Whole Slide Imaging in cytology retains most of the advantages of surgical pathology, and in the near future barriers to adoption will be overcome.
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The Official Journal of the British Association for Cytopathology and an Affiliated Journal of over 20 National Cytology Societies
