Edited By: Eisuke Nishida
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Isolation of planarian viable cells using fluorescence‐activated cell sorting for advancing single‐cell transcriptome analysis
-  18 September 2023
Pkd2, mutations linking to autosomal dominant polycystic kidney disease, localizes to the endoplasmic reticulum and regulates calcium signaling in fission yeast
-  18 September 2023
A series of truncation analyses of fission yeast Pkd2 revealed that Pkd2 localizes to the ER via transmembrane domains and regulates the cytoplasmic calcium signaling. Human Pkd2 localized to the ER and has some effect on activation of cytoplasmic calcium signaling in fission yeast; however, human PKD2 could not rescue the loss of pkd2 in fission yeast.
Yeast Tor complex 1 phosphorylates eIF4E-binding protein, Caf20
-  12 September 2023
Lumicrine signaling: Extracellular regulation of sperm maturation in the male reproductive tract lumen
-  11 September 2023
The behaviors of cells, tissues, and organs are controlled by the extracellular environment in addition to their autonomous regulatory system. Lumicrine signaling is a transluminal secreted signal transduction in the male reproductive tract lumen through which sperm functional maturation is regulated.
Wnt10b knockdown promotes UCP1 expression in brown adipose tissue in mice
-  10 September 2023
Wnt10b, a crucial member of the Wnt gene family, is involved in many physiological processes. However, the impact of Wnt10b knockdown on the function of brown adipose tissue is yet largely unknown. This study indicates that Wnt10b knockdown enhances UCP1 expression and inhibits the adipogenic differentiation of brown adipocytes, providing a novel option for therapeutic interventions in adiposity.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution
-  20 January 2011
Role of Bcl‐2 family proteins in apoptosis: apoptosomes or mitochondria?
-  25 December 2001
Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles
-  25 March 2003
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-  12 January 2002