Edited By: Eisuke Nishida
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CD271 promotes proliferation and migration in bladder cancer
-  28 November 2023
Brain-derived neurotrophic factor (BDNF) downregulates mRNA levels of suppressor of cancer cell invasion (SCAI) variants in cortical neurons
-  27 November 2023
IMPDH2 forms spots at branching sites and distal ends of astrocyte stem processes
-  27 November 2023
Visualization of the landscape of the read alignment shape of ATAC-seq data using Hellinger distance metric
-  21 November 2023
We introduced a novel concept and pipeline for handling the pure shape information of NGS data as probability distributions and quantifying their dissimilarities by information theory. Based on this concept, we demonstrate that the pure shape information of ATAC-seq data is correlated with chromatin openness and some gene characteristics.
Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I
-  20 November 2023
The immune-related GTPase Irgb6 is markedly phosphorylated at Thr95 in response to Toxoplasma infection. Phosphorylation of Thr95 not only inactivates the GTPase activity of Irgb6 but also abrogates its binding to the Toxoplasma membrane. Structural studies elucidated the structural basis of Irgb6 inactivation by phosphorylation of Thr95 through allosteric conformational changes from the GTP pocket to the membrane binding interface.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution
-  20 January 2011
Role of Bcl‐2 family proteins in apoptosis: apoptosomes or mitochondria?
-  25 December 2001
Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles
-  25 March 2003
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-  12 January 2002