Edited By: Maura Corsetti Associate Editor(s): Christopher Black, Frank Zerbib, Kirsteen Browning, Fedias Christofi, Mike Jones, Andrea Shin
Media Editor: Daniel Keszthelyi
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Neurogastroenterology & Motility is an open access gastroenterology journal where current issues and advances relating to the motor function of the GI tract can be presented and discussed.
The journal is of interest to both clinicians and researchers, publishing original research and topical reviews on basic and clinical aspects of gastrointestinal motility and its control, brain-gut interactions, and how nervous systems interact in the control of gastrointestinal functions.
Featured Articles | December 2024 Editor's Choice
Unsupervised machine learning highlights the challenges of subtyping disorders of gut-brain interaction
Jarrah M. Dowrick, Nicole C. Roy, Simone Bayer, Chris M. A. Frampton, Nicholas J. Talley, Richard B. Gearry, Timothy R. Angeli-Gordon
A primer for the gastroenterology provider on psychosocial assessment of patients with disorders of gut-brain interaction
Sarah Ballou, Dipesh H. Vasant, Livia Guadagnoli, Bonney Reed, Giuseppe Chiarioni, Liesbeth ten Cate, Laurie Keefer, Sarah W. Kinsinger
Multidisciplinary behavioral therapy reduces rumination
M. Nyyssönen, O. Vilpponen, M. Ståhl-Railila, S. Liesto, T. Mustonen, S. Pikkarainen, P. Arkkila, R. Roine, H. Sintonen, J. Punkkinen
FAAH inhibitor URB597 shows anti-hyperalgesic action and increases brain and intestinal tissues fatty acid amides in a model of CRF1 agonist mediated visceral hypersensitivity in male rats
Muriel Larauche, Agata Mulak, Chrysanthy Ha, Mulugeta Million, Stacy Arnett, Peter Germano, James P. Pearson, Mark G. Currie, Yvette Taché
Diagnostic classification systems for disorders of gut-brain interaction should include psychological symptoms
Michael P. Jones, Gerald J. Holtmann, Jan Tack, Florencia Carbonne, William Chey, Natasha Koloski, Ayesha Shah, Shrikant I. Bangdiwala, Ami D. Sperber, Olafur S. Palsson, Nicholas J. Talley
On the Cover
The cover image is based on the Original Circadian rhythm and whole gut transit in mice by Emma Laible et al., https://doi.org/10.1111/nmo.14771.
The cover image is based on the Original Article Curricular representation of neurogastroenterology: A survey among medical students in Germany by Patejdl et al., 10.1111/nmo.14557.
The cover image is based on the Review Article The Rome Foundation Global Epidemiology study: Conception, implementation, results, and future potential by Ami D. Sperber et al., https://doi.org/10.1111/nmo.14567.
Articles
Smooth Muscle Mechanosensitivity Generates and Maintains Pressure Gradients Across the Intestine
- 9 December 2024
Graphical Abstract
Mechanosensitivity of the smooth muscle induces a positive-feedback loop that spontaneously generates pressure gradients across gut segments and stabilizes initially applied pressure gradients. It can act jointly or compete with the pressure gradient induced by directional peristaltic waves. High pressure differentials can reverse the physiological propagation direction of contractile waves.
Chemotherapy‐Induced Neuropathy Affecting the Gastrointestinal Tract
- 9 December 2024
Graphical Abstract
Chemotherapy (with/without immunotherapy/radiotherapy) may induce neurotoxic effects on the gastrointestinal innervation. Chemotherapy-induced enteric neuropathy (CIEN) and, probably, neurotoxicity affecting the extrinsic innervation of the gut and the brain underlie the frequent and impactful gut dysfunctions and brain–gut axis (BGA) disorders occurring in the long term in cancer survivors.
Functional Lumen Imaging Probe Panometry Findings in Obese Patient Populations
- 8 December 2024
Graphical Abstract
FLIP metrics such as median EGJ diameter and DI were similar between surgery-naïve and post-bariatric surgery (SG or RYGB) obese patients. However, contractile response patterns were abnormal in approximately two-thirds of obese patients with SG and RYGB patients having higher rates of ACR and lower rates of SRCR compared to surgery-naïve patients. While FLIP contractile response abnormalities did not predict symptoms, 12% of symptomatic obese patients with no HRM diagnosis demonstrated a reduced FLIP–EGJ opening, suggesting that FLIP can have clinical value in this cohort.
Assessing the Clinical Value of 2‐h Versus 4‐h Gastric Emptying Scintigraphy in Pediatrics: A Systematic Review and Meta‐Analysis
- 5 December 2024
Graphical Abstract
Graphical abstract of the meta-analysis performed to evaluate the association of an extended 4-h gastric emptying scintigraphy scan on diagnostic yield for the detection of gastroparesis in a pediatric population. The results of the pooled analysis suggest an increased overall detection of gastroparesis with an extended 4-h scan
Prospective Evaluation of Autonomic Function and Intestinal Blood Flow in Health and Irritable Bowel Syndrome Shows Differences Limited to Patients With Constipation Predominance
- 3 December 2024
Graphical Abstract
Systemic autonomic function and localized intestinal blood flow dynamics in IBS patients were studied, accounting for predominant bowel habits and controlling for psychological comorbidity. Some novel differences were revealed compared to healthy controls; confined to patients with constipation-predominant IBS, especially in the fasting state.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0©
- 29 December 2020
Graphical Abstract
Key updates in the CCv4.0 include a protocol inclusive of varying positions and provocative tests, recognitions of conclusive and inconclusive patterns, requirement of clinically relevant symptoms for a conclusive diagnosis of EGJOO, distal esophageal spasm or hypercontractile esophagus, and increasingly stringent criteria for EGJOO and IEM.The classification using CCv4.0 is based on the primary position (either supine or upright), while assessment of swallows in the secondary position and with provocation provides supportive data, particularly for inconclusive settings.
Listen to the podcast for this article.
The Chicago Classification of esophageal motility disorders, v3.0
- 160-174
- 3 December 2014
Graphical Abstract
View the podcast on this paper at the following sites:
Youtube: https://www.youtube.com/watch?v=zHFT4mj-Yw4&feature=youtu.be
iTunes: https://itunes.apple.com/gb/podcast/neurogastroenterology-motility/id955822234
The Chicago Classification (CC) of esophageal motility disorders, utilizing an algorithmic scheme to analyze clinical high-resolution manometry (HRM) studies, has gained acceptance worldwide. This 2014 update, CC v3.0, developed by the International HRM Working Group, incorporated the extensive clinical experience and interval publications since the prior (2011) version.
Correlation between the human fecal microbiota and depression
- 1155-1162
- 1 June 2014
Graphical Abstract
We found a significant correlation between the gut microbiota and depression in humans. The correlations, however, were in opposite direction for closely related Operational Taxonomic Units (OTU's).
Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0©
- Neurogastroenterology & Motility
- 29 December 2020
Graphical Abstract
Key updates in the CCv4.0 include a protocol inclusive of varying positions and provocative tests, recognitions of conclusive and inconclusive patterns, requirement of clinically relevant symptoms for a conclusive diagnosis of EGJOO, distal esophageal spasm or hypercontractile esophagus, and increasingly stringent criteria for EGJOO and IEM.The classification using CCv4.0 is based on the primary position (either supine or upright), while assessment of swallows in the secondary position and with provocation provides supportive data, particularly for inconclusive settings.
Listen to the podcast for this article.
The Chicago Classification of esophageal motility disorders, v3.0
- Neurogastroenterology & Motility
- 160-174
- 3 December 2014
Graphical Abstract
View the podcast on this paper at the following sites:
Youtube: https://www.youtube.com/watch?v=zHFT4mj-Yw4&feature=youtu.be
iTunes: https://itunes.apple.com/gb/podcast/neurogastroenterology-motility/id955822234
The Chicago Classification (CC) of esophageal motility disorders, utilizing an algorithmic scheme to analyze clinical high-resolution manometry (HRM) studies, has gained acceptance worldwide. This 2014 update, CC v3.0, developed by the International HRM Working Group, incorporated the extensive clinical experience and interval publications since the prior (2011) version.
Correlation between the human fecal microbiota and depression
- Neurogastroenterology & Motility
- 1155-1162
- 1 June 2014
Graphical Abstract
We found a significant correlation between the gut microbiota and depression in humans. The correlations, however, were in opposite direction for closely related Operational Taxonomic Units (OTU's).
Latest news
Recent issues
Volume 36, Issue 12December 2024
Volume 36, Issue 11November 2024
Volume 36, Issue 10October 2024
Impact Factor and Citation Awards
Most Cited Original Article Award
The editors are pleased to announce that the most cited Neurogastroenterology & Motility original paper published in volume 33 is Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0© by Rena Yadlapati, Peter J. Kahrilas, Mark R. Fox, Albert J. Bredenoord, C. Prakash Gyawali, Sabine Roman, Arash Babaei, Ravinder K. Mittal, Nathalie Rommel, Edoardo Savarino, Daniel Sifrim, André Smout, F. Vaezi,Frank Zerbib, Junichi Akiyama, Shobna Bhatia, Serhat Bor, Dustin A. Carlson, Joan W. Chen, Daniel Cisternas, Charles Cock, Enrique Coss-Adame, Nicola de Bortoli, Claudia Defilippi, Ronnie Fass, Uday C. Ghoshal, Sutep Gonlachanvit, Albis Hani, Geoffrey S. Hebbard, Kee Wook Jung, Philip Katz, David A. Katzka, Abraham Khan, Geoffrey Paul Kohn, Adriana Lazarescu, Johannes Lengliner, Sumeet K. Mittal, Taher Omari, Moo In Park, Roberto Penagini, Daniel Pohl, Joel E. Richter, Jordi Serra, Rami Sweis, Jan Tack, Roger P. Tatum, Radu Tutuian,Marcelo F. Vela, Reuben K. Wong, Justin C. Wu, Yinglian Xiao, John E. Pandolfino. Congratulations!
Fast Track Option for Clinical Trial Papers
Did you know that if you submit your clinical trial paper to Neurogastroenterology and Motility you could get a decision on your paper in just 10 days?
Did you also know that once accepted, if you return your proof within 3 days your paper will be published online in Early View in just 15 days?
This means your clinical trial research could be available to cite in around 25 days from submission to publication!
To submit your paper online today simply click here
Society Partnerships
Neurogastroenterology and Motility is the official journal of the American Neurogastroenterology and Motility Society and the European Society of Neurogastroenterology and Motility.
