Journal list menu
Reproductive Medicine and Biology (RMB) is the official English language open access journal of the Japan Society for Reproductive Medicine, the Japan Society of Fertilization and Implantation, the Japan Society of Andrology, Asian Society of Endometriosis and Adenomyosis, and the Japan Society for Ova Research, and welcomes submissions from the members and the non-members. Reproductive Medicine and Biology publishes original research articles that report new findings or concepts in all aspects of reproductive phenomena in all kinds of mammals.
Risk factors for empty follicle syndrome in assisted reproductive technology with gonadotropin‐releasing hormone agonist trigger
-  9 December 2023
Clinical outcomes of personalized blastocyst embryo transfer after endometrial receptivity analysis: A multicenter, retrospective cohort study
-  29 November 2023
An approach for live imaging of first cleavage in mouse embryos using fluorescent chemical probes for DNA, microtubules, and microfilaments
-  27 November 2023
Non‐medical oocyte cryopreservation at a single center in Japan: 8 years of experience
-  10 November 2023
Sperm DNA fragmentation testing in clinical management of reproductive medicine
-  31 October 2023
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Animal‐cell culture media: History, characteristics, and current issues
-  21 March 2017
Molecular mechanism of estrogen–estrogen receptor signaling
-  5 December 2016
Decidualization of the human endometrium
-  1 February 2018
Interaction between growing oocytes and granulosa cells in vitro
-  22 August 2019
Analysis of endometrial microbiota by 16S ribosomal RNA gene sequencing among infertile patients: a single-center pilot study
-  6 May 2018
Recent researches on mammalian spermatozoa
In mammalian testes, spermatogonia are distributed in the basal part of seminiferous tubules and proliferate mitotically. Some of them undergo the processes of meiosis and spermiogenesis, and then differentiate into spermatozoa. However, spermatozoa are still functionally immature in the testes and gradually acquire the potential to move progressively and fertilize oocytes during the transit through the epididymis. After ejaculation into female reproductive tract, spermatozoa undergo a variety of physiological and morphological changes including capacitation, flagellar hyperactivation and acrosome reaction, and finally achieve fertilization with oocytes in the ampulla of the oviduct. Recently, basic studies of these research fields are making rapid progress by using cell biological and molecular biological methods, especially techniques of gene manipulation. Meanwhile, although several decades have already passed since practical application of the artificial insemination using cryopreserved semen in mammals (cattle), there are recent problems of subfertility in both males and females which result in lowering productivity of the offspring (calves). In order to overcome these problems, the applied studies have made a significant achievement in the development of reproductive biotechnology. On this page, five RMB-invited review articles which are related to the basic and applied studies on mammalian spermatozoa (including male germ cells) are introduced as Editor's choice. My hope is that they would be helpful for the improvement of clinical activities as well as activities of basic researches and animal industries.
Editor, Hiroshi Harayama
Biology and manipulation technologies of male germline stem cells in mammals
Flagellar hyperactivation of bull and boar spermatozoa
Bovine sperm sex‐selection technology in Japan
In Japan, Livestock Improvement Association of Japan started commercially producing sexed bovine semen 10 years ago, and it is now commonly used on Japanese farms. In this review, the authors introduce the technology for sperm sexing by flow cytometry, the efforts at commercializing sexed semen in Japan, and recent field data on artificial insemination of cattle with sexed semen.