New Editor-in-Chief, James Sleigh

New Editor-in-Chief, James Sleigh

James is a Senior Research Fellow and Principal Investigator in the Department of Neuromuscular Diseases at the UCL Queen Square Institute of Neurology, London.

Funded by the Medical Research Council, the Sleigh Laboratory works to understand the molecular and cellular processes driving neuropathology in genetic diseases of the peripheral nervous system, such as Charcot-Marie-Tooth disease (CMT) and amyotrophic lateral sclerosis (ALS).

Using mouse models, live imaging and comparative morphological assessments, Dr. Sleigh’s team study causes of motor and sensory nerve vulnerability to degeneration and the mechanisms underpinning the dynamic process of axonal transport. By improving knowledge of neuronal pathways and associated pathologies, the principal goal of the Sleigh Laboratory is to generate effective, pre-clinical gene therapies for currently untreatable diseases of the peripheral nerves.



The Anatomical Society announces the appointment of a new Early Career Researcher Editorial Board

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The Journal of Anatomy Best Paper Prize (anatsoc.org.uk)

2022 Award

Journal of Anatomy Best Paper Award

Precision mouse models of Yars/dominant intermediate Charcot-Marie-Tooth disease type C and Sptlc1/hereditary sensory and autonomic neuropathy type 1 


Timothy J. Hines, Abigail L. D. Tadenev, Museer A. Lone, Courtney L. Hatton, Inseyah Bagasrawala, Morgane G. Stum, Kathy E. Miers, Thorsten Hornemann, Robert W. Burgess 

Journal of Anatomy, Volume 241, Issue 5, November 2022, Pages 1169-1185

Journal of Anatomy: Vol 241, No 5 (wiley.com)


Journal of Anatomy Runner-Up Best Paper Prize


Comprehensive expression analysis for the core cell cycle regulators in the chicken embryo reveals novel tissue-specific synexpression groups and similarities and differences with expression in mouse, frog and zebrafish

Marta Alaiz Noya, Federica Berti, Susanne Dietrich

Journal of Anatomy, Volume 241, Issue 1, July 2022, Pages 42– 66 

https://onlinelibrary.wiley.com/toc/14697580/2022/241/1

 



 

 

NEW RESEARCH STUDENTSHIPS 2023/24 - AWARDED FOR START DATE 01.10.24

 

Award of Anatomical Society Studentships

We are seeking applications from the Anatomical Society Membership for the 2023/24 round (student start date 1st October 2024). Application details can be found here.

Click here to read more about the 2023/24 Research Studentships

 

Articles

ORIGINAL ARTICLE

Whole-brain mapping of monosynaptic afferent inputs to the CRH neurons in the medial prefrontal cortex of mice

  •  27 November 2023

Graphical Abstract

Description unavailable

Summarized the monosynaptic inputs to the mPFCCRH neurons in the whole brain. Blue represents the cortex, red represents the thalamus, and purple represents other brain regions. The thickness of each line indicates the proportion of projection neurons in each area.

BRIEF COMMUNICATION
Open access

Glial cells are affected more than interneurons by the loss of Engrailed 2 gene in the mouse cerebellum

  •  27 November 2023

Graphical Abstract

Description unavailable

Engrailed-2 knockout mice (En2−/−) are a model for autism spectrum disorder (ASD), moreover the role of the cerebellum in ASD has been established. In this context, we conducted an immunohistochemical analysis to investigate whether changes in glial and/or interneurons occur in the cerebellum of En2−/− mice compared to wild-type in both males and females.

ORIGINAL ARTICLE

Corona mortis and pelvic dissection: Understanding the relationship between anatomical structures and bone areas

  •  22 November 2023

Graphical Abstract

Description unavailable

We were able to perform an extraperitoneal endoscopic dissection of the pelvis with no significant difference between our method and a traditional open approach in terms of bone exposure. We propose a holistic approach to treat pelvic fractures by identifying key anatomical structures.

BRIEF COMMUNICATION
Open access

Reinterpretation of tuberculate cervical vertebrae of Eocene birds as an exceptional anti‐predator adaptation against the mammalian craniocervical killing bite

  •  22 November 2023

Graphical Abstract

Description unavailable

We report avian cervical vertebrae from the late Eocene Phosphorites du Quercy in France that are densely covered with tubercles. Micro-computed tomography shows these fossils to have a remarkably thick cortex and dense interior. We hypothesize that this unique vertebral morphology served to strengthen the cervical column in the upper part of the neck and represents an anti-predator adaptation against the mammalian craniocervical killing bite (“neck bite”).

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