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Editor in Chief: John Kuriyan
Senior Editors: Nir Ben-Tal and Aitziber L. Cortajarena
About the Journal
Protein Science, the flagship journal of The Protein Society, serves an international forum for publishing original reports on all scientific aspects of protein molecules. The Journal publishes papers by leading scientists from all over the world that report on advances in the understanding of proteins in the broadest sense. Protein Science aims to unify this field by cutting across established disciplinary lines and focusing on “protein-centered” science.
For inquiries regarding manuscripts under review, contact: proteinscience@wiley.com

The Protein Society and senior editors of Protein Science announce and congratulate the winners of the 2021 Best Paper Awards: Chelsea Vickers (Victoria University of Wellington), Ryan Woloschuk (University of Toronto), and Max Reed (University of Toronto). Read more in the press release here.
Featured
Articles
Structural studies of antitumor compounds that target the RING domain of MDM2
-  21 July 2022
Uniform binding and negative catalysis at the origin of enzymes
-  14 July 2022
Heterologous expression of naturally evolved putative de novo proteins with chaperones
-  13 July 2022
Core packing of well-defined X-ray and NMR structures is the same
-  13 July 2022
UCSF ChimeraX: Structure visualization for researchers, educators, and developers
- Protein Science
-  70-82
-  3 September 2020
The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions
- Protein Science
-  187-200
-  18 October 2020
DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations
- Protein Science
-  60-69
-  3 September 2020
Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein
- Protein Science
-  2038-2042
-  21 August 2020
The Human Protein Atlas—Spatial localization of the human proteome in health and disease
- Protein Science
-  218-233
-  4 November 2020
The ImageJ ecosystem: Open-source software for image visualization, processing, and analysis
- Protein Science
-  234-249
-  9 November 2020
KEGG mapping tools for uncovering hidden features in biological data
- Protein Science
-  47-53
-  23 August 2021
How to use the MEROPS database and website to help understand peptidase specificity
- Protein Science
-  83-92
-  13 September 2020
Leginon: New features and applications
- Protein Science
-  136-150
-  8 October 2020
The collection consists of our top 10 recent reviews that have been published in 2017 and 2018.
While the revolution will not be crystallized, biochemistry reigns supreme
- Protein Science
-  69-81
-  10.1002/pro.3054
Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM
- Protein Science
-  82-92
-  10.1002/pro.3068
A cell is more than the sum of its (dilute) parts: A brief history of quinary structure
- Protein Science
-  403-413
-  10.1002/pro.3092
(S)Pinning down protein interactions by NMR
- Protein Science
-  436-451
-  10.1002/pro.3105
Modulating the wnt signaling pathway with small molecules
- Protein Science
-  650-661
-  10.1002/pro.3122
Targeting human SET1/MLL family of proteins
- Protein Science
-  662-676
-  10.1002/pro.3129
Monobodies and other synthetic binding proteins for expanding protein science
- Protein Science
-  910-924
-  10.1002/pro.3148
Global substrate specificity profiling of post-translational modifying enzymes
- Protein Science
-  584-594
-  10.1002/pro.3352