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Angewandte Chemie is a journal of the German Chemical Society (GDCh). It is one of the prime chemistry journals in the world. It is the only journal in the field delivering a stimulating mixture of Review-type articles, Highlights, Communications, and Research Articles. New articles appear online almost every day.

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February 23, 2021

Angewandte Chemie 10/2021: A Roadmap for Chemistry

anie.202181061.jpgIn this issue, S. Kaskel et al. review porphyrin-based metal–organic frameworks for biomedical applications. C. Yang et al. summarize performance-enhancing approaches for PEDOT:PSS-Si hybrid solar cells. The Minireviews deal with binary (split) light-up aptameric sensors (D. M. Kolpashchikov, A. A. Spelkov) and activity-based sensing probes for isoform-selective imaging of enzymatic activity (J. Chan et al.). In his Guest Editorial, J. Garcia-Martinez presents a roadmap for chemistry in the new decade.

In the original research section, S. R. Waldvogel et al. describe a metal-free electrochemical synthesis of sulfonamides directly from (hetero)arenes, SO2, and amines (see picture). S. Komaba et al. succeeded in the MgO-template synthesis of extremely high capacity hard carbon for Na-ion batteries. S. Ma et al. developed a MOF-based ultra-strong acetylene nano-trap for highly efficient C2H2/CO2 separation. R. M. Rodriguez Sarmiento et al. found novel β-glucocerebrosidase activators that bind to a new pocket at a dimer interface and induce dimerization. T. H. Ware et al. demonstrate 4D-printing of photoswitchable actuators.

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Editorial

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Chemistry 2030: A Roadmap for a New Decade

  •  4956-4960
  •  1 February 2021

Abstract

This new decade poses many new challenges at many different levels. The SIDE vision for Chemistry 2030 gathers the main recommendations from various organizations and initiatives and provides a roadmap for the advancement of chemistry and to respond to increasingly complex and interconnected challenges.

Press Release

Screening for Macrocyclic Peptides

Dimeric cyclic peptides are potent modulators of ubiquitin, an apoptosis regulator

Screening for Macrocyclic Peptides - Dimeric cyclic peptides are potent modulators of ubiquitin, an apoptosis regulator

Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, a protein that helps to degrade proteins and induce cell death. The results could lead to novel drug candidates against cancer, according to the study published in the journal Angewandte Chemie.

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