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Editor: Neville Compton, Deputies: Frank Maass, Nathalie Weickgenannt; Editorial Board Chair: Annette G. Beck-Sickinger
About
Angewandte Chemie is a journal of the German Chemical Society (GDCh). It is one of the prime chemistry journals in the world. It is the only journal in the field delivering a stimulating mixture of Review-type articles, Highlights, Communications, and Research Articles. New articles appear online almost every day.
On the Cover
Latest News
May 19, 2020
Angewandte Chemie 22/2020: Fundamental Mechanisms
In this issue, M. Lansalot et al. review RAFT-mediated polymerization-induced self-assembly. What role does radical controlled/living polymerization play? The Minireviews deal with abiotic chemical fuels for molecular machines (C. Biagini, S. Di Stefano) and heavy-atom tunneling in organic reactions (C. Castro, W. L. Karney). C. Wentrup contributes an Essay on the history of olefin π-complexes, and D. Janssen-Müller and M. Oestreich highlight the bismuth-catalyzed C–F coupling of aryl boronic esters.
In the original research section, J. Crassous et al. describe the influence of helicene, halogen, and stereochemistry on the emission properties of helicene-NHC rhenium(II) complexes (see picture). Y. Ge et al. developed high-throughput proteomics enabled by a photocleavable surfactant. N. A. Kotov et al. present diverse nanoassemblies of graphene quantum dots and their mineralogical counterparts. R. M. Bullock et al. studied the mechanism of insertion of carbonyl substrates into Cu–H.
Press Release
Staining Cycles with Black Holes
Ultrafast repeated staining and destaining of cell samples for tumor diagnostics
In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. In the journal Angewandte Chemie, scientists have introduced a method by which cell samples from tumors and their surroundings can rapidly (under 1 hour) be cycled through staining, destaining, and then restaining with fluorescent antibodies—through attachment of a “black hole quencher” (fluorescence quencher) by means of “click chemistry”.
Author Profile

“I advise my new students to learn more physics. Physics gives us fundamental understanding and cultivates logical thinking … The greatest scientific advance of the last decade was the combination of chemistry and machine learning …” Find out more about Jie Zeng in his Author Profile.
Angewandte Chemie International Edition 2020, 59, No. 22, 8326.
Editorial
Neville Compton
Angewandte Chemie —The Home of Excellent Chemistry

Opening its doors to even more excellent chemistry, Angewandte Chemie's decision to add Research Articles has further expanded the choices available to authors. The flagship journal of the German Chemical Society now offers a home for all different forms of excellent chemistry.
Angewandte Chemie International Edition 2020, 59, No. 1, 4–7.
Articles
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Beyond Frameworks: Structuring Reticular Materials across Nano, Meso, and Bulk Regimes
-  24 May 2020
A Diselenide turn‐on Fluorescent Probe for the Detection of Thioredoxin Reductase
- Tendai J. Mafireyi
- Madeleine Laws
- John W. Bassett
- Pamela B. Cassidy
- Jorge O. Escobedo
- Robert Michael Strongin
-  24 May 2020
Deciphering the Intersystem Crossing in a Helical BODIPY for Recorded Low Dose Photodynamic Therapy
- Zhijia Wang
- Ling Huang
- Yuxin Yan
- Ahmed M. El-Zohry
- Antonio Toffoletti
- Jianzhang Zhao
- Antonio Barbon
- Bernhard Dick
- Omar F. Mohammed
- Gang Han
-  24 May 2020
Direct observation of aggregation‐induced emission mechanism
- Jianxin Guan
- Antonio Prlj
- Rong Wei
- Jie Peng
- Kun-Han Lin
- Jitian Liu
- Han Han
- Zhihao Yu
- Clémence Corminboeuf
- Dahui Zhao
- Junrong Zheng
-  22 May 2020
Ultrahighly Branched Main‐Chain‐Functionalized Polyethylenes via Inverted Insertion Selectivity
-  22 May 2020
A Blinking Mesoporous TiO2‐x Composed of Nanosized Anatase with Unusually Long‐Lived Trapped Charge Carriers
-  22 May 2020
Open accessAl2Pt for Oxygen Evolution in Water Splitting: a Strategy for Creating Multi‐functionality in Electrocatalysis
- Iryna Antonyshyn
- Ana Maria Barrios Jimenez
- Olga Sichevych
- Ulrich Burkhardt
- Igor Veremchuk
- Marcus Schmidt
- Alim Ormeci
- Ioannis Spanos
- Andrey Tarasov
- Detre Teschner
- Gerardo Algara-Siller
- Robert Schlögl
- Yuri Grin
-  22 May 2020
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The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
morefree accessClick Chemistry: Diverse Chemical Function from a Few Good Reactions
-  2004-2021
-  28 May 2001
Abstract
Just a handful of good reactions are needed to assemble vast numbers of highly diverse organic molecules. (The graphic shows a simple example.) Yet, this easily accessible structural universe has not been mined by the medicinal chemistry community for its nuggets of desirable function. The requirements for the best reactions that can be employed, examples of such processes, and the philosophy that underlies their use are discussed in this review.
A Stepwise Huisgen Cycloaddition Process: Copper(I)‐Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
-  2596-2599
-  15 July 2002
free accessCellulose: Fascinating Biopolymer and Sustainable Raw Material
-  3358-3393
-  24 May 2005
Abstract
The trend toward renewable resources has led to a global renaissance of cellulose research over the past ten years. This review describes the highlights of the progress made in this area, which has provided a better understanding of the structure of cellulose derivatives, the tailoring of cellulose products, alternative production processes for cellulose regenerates, and new pathways for the formation of supramolecular architectures.
Functional Porous Coordination Polymers
-  2334-2375
-  22 April 2004
Abstract
Nanospace laboratories : The chemistry of the coordination polymers (see picture) has developed extensively, affording new porous compounds and realizing not only applications, such as separation, storage, and heterogeneous catalysis but also unique nanosized vessels for low‐dimensional ordered arrays. This Review summarizes the current state of research on the functionalization of porous coordination polymers.
Magnetic Nanoparticles: Synthesis, Protection, Functionalization, and Application
-  1222-1244
-  5 February 2007
Abstract
Particularly attractive : Magnetic nanoparticles can be prepared and protected against corrosion in a variety of ways (Scheme: polystyrene (PS) coating of MnFe2O4 particles by atom‐transfer radical polymerization). The protected magnetic nanoparticles can be further functionalized for many applications including catalysis and biotechnology.
Luminescent Carbon Nanodots: Emergent Nanolights
-  6726-6744
-  4 August 2010
Abstract
A glowing review : Carbon nanodots have recently emerged as intriguing, cheap, sustainable, and low‐toxicity nanoemitters that hold immense promise in energy conversion, bioimaging, diagnostics, and novel composites. This Review summarizes recent advances in the synthesis, understanding, and exploitation of carbon‐based quantum dots as nascent biolabels, while pointing to potential new directions for this fascinating class of nanocarbon.
Nanomaterials for Rechargeable Lithium Batteries
-  2930-2946
-  1 April 2008
Abstract
Rechargeable lithium batteries have developed into the dominant energy source for portable electronic devices because of their high energy density. Nanomaterials are pivotal for further development in this area, as their special properties can greatly increase the efficiency of such batteries. The picture shows a lithium nanobattery incorporating a TiO2(B) nanowire anode and nanoparticulate Li(Ni1/2Mn3/2)O4 cathode.
Shape‐Controlled Synthesis of Metal Nanocrystals: Simple Chemistry Meets Complex Physics?
-  60-103
-  18 December 2008
Abstract
Function follows form : Controlling the shape of nanocrystals may initially seem like a scientific curiosity, but its goal goes far beyond aesthetic appeal. For metal nanocrystals, shape not only determines their intrinsic physical and chemical properties but also their relevance for electronic, magnetic, optical, catalytic, and sensing applications.
Nanocelluloses: A New Family of Nature‐Based Materials
- Dieter Klemm
- Friederike Kramer
- Sebastian Moritz
- Tom Lindström
- Mikael Ankerfors
- Derek Gray
- Annie Dorris
-  5438-5466
-  20 May 2011
Abstract
Cellulose goes nano : Renewed research effort on cellulose has led to nanoscale materials derived from this abundant, renewable, and potentially carbon‐neutral source. Microfibrillated cellulose, nanocrystalline cellulose (see polarized microscopy image), and bacterial nanocellulose provide unique product opportunities: gels and foams, structured films of cellulose, and medical implants, respectively.
Highly Photoluminescent Carbon Dots for Multicolor Patterning, Sensors, and Bioimaging
- Shoujun Zhu
- Qingnan Meng
- Lei Wang
- Junhu Zhang
- Yubin Song
- Han Jin
- Kai Zhang
- Hongchen Sun
- Haiyu Wang
- Bai Yang
-  3953-3957
-  28 February 2013
Abstract
Shine on you crazy dots : A rapid and high‐output strategy allows the fabrication of polymer‐like carbon dots (CDs) with quantum yields as high as ca. 80 %. This value is the highest reported to date for fluorescent carbon‐based materials, and gives promise for their application in multicolor‐patterning and biosensors.







































