Therapeutic dose anticoagulation is more effective in preventing thromboembolic events than prophylactic dose but significantly increases the risk of major bleeding as an adverse event. So, the risk–benefit ratio must be considered while using either of them.

In this report, we present data from evaluation of HER2/neu overexpression in 100 patients who diagnosed with lung cancer. The results showed that HER2/neu was overexpressed not only in adenocarcinoma but also in other types, like squamous cell carcinoma.

The risk of death in COVID-19 patients with chronic liver disorders was higher than in ones without the chronic liver disease (RR: 1.52; CI 95%: 1.46–1.57; I²: 86.14%).

This study describes the clinical and pathological features of fibrotic hypersensitivity pneumonitis diagnosed with transbronchial lung crybiopsy. Usual interstitial pneumonia was the most frequent pathological finding of fibrotic hypersensitivity pneumonitis. Transbronchial lung crybiopsy could be considered as a diagnostic technique for fibrotic hypersensitivity pneumonitis.

This study assessed the effects of continuous positive airway pressure (CPAP) compliance on acute exacerbations of COPD, symptoms and pulmonary function in patients with overlap syndrome (OS). In total, 59 patients (54 males) with OS were followed for 12 months and divided post hoc according to CPAP compliance into those with good (≥4 h CPAP use/night, n = 29) and those with poor (<4 h CPAP use/night, n = 30) CPAP compliance. COPD exacerbations decreased in patients with good CPAP compliance from baseline to 12 months (17 before vs. 5 after, p = 0.001), but not in those with poor compliance (15 before vs. 15 after, p = 1).

We conducted a meta-analysis of AECOPD mortality risk prediction models. The results showed that DECAF performs well in predicting in-hospital death [C-statistic = 0.91, 95%CI: 0.83–0.98] and 90-day death [C-statistic = 0.76, 95%CI: 0.69–0.82] and CURB-65 performs well in predicting 30-day death [C-statistic = 0.74, 95%CI: 0.70–0.77].

We compare the demographic and clinical features, laboratory and imaging findings in mycoplasma pneumoniae pneumonia (MPP) children with non-MPP (NMPP) children and general MPP (GMPP) children with refractory MPP (RMPP) children and analysis the relationship with the severity of disease. This study showed that the measurement of IL-6, LDH, IL-10 and D-dimer can be useful predictors for RMPP. There were differences in clinical characteristics and serum inflammatory markers between MPP group and NMPP group, RMPP group and GMPP group.

Single dose nebulized verapamil inhalation showed improvement in V/Q mismatch throught increase FVC. Nebulized verapamil inhalation improved gas exchanged and increased spO2. Nebulized verapamil inhalation for out-patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease improved spirometric parameter. The FEV1/FVC ratio decreased significantly after verapamil administration due to more potent bronchodilator on small airways.

This study reviewed 2013–2018 US insurance claims data to compare the incidence rates of herpes zoster among people 40 years and older with and without chronic obstructive pulmonary disease. Adjusting for baseline demographics and clinical characteristics, this study found that people with chronic obstructive pulmonary disease were nearly three times more likely to develop herpes zoster than those without.