Journal of Diabetes (JDB) is an open access diabetes and metabolism journal devoted to diabetes research, therapeutics, and education. The journal aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. JDB is an official journal of the Chinese Society of Endocrinology endorsed by the Chinese Endocrinologist Association.

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Glucagon-like peptide-1 receptor agonists and kidney outcomes

  •  4 October 2024

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Glucagon-like peptide-1 receptor agonists and kidney outcomes Issue 10, 2024

Highlights

  • Evidence from GLP-1RAs CVOTs show that GLP-1RAs reduce albuminuria but slowing of progression to chronic kidney failure remains to be proven.
  • The FLOW trial is the first study assessing the usefulness of a once-weekly subcutaneous GLP-1RA (semaglutide) in slowing progression to clinically important kidney end points and protection form cardiovascular disease people with T2DM and established CKD.
  • FLOW will help guide the optimal use of GLP-1RAs in the clinical care of people with T2DM and CKD.

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Prevalence and influencing factors of malnutrition in diabetic patients: A systematic review and meta‐analysis

  •  4 October 2024

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Prevalence and influencing factors of malnutrition in diabetic patients: A systematic review and meta-analysis Issue 10, 2024

Highlights

  • The overall prevalence of malnutrition in diabetic patients was 33% (95% CI: 0.25–0.40), and the at-risk prevalence of malnutrition was 44% (95% CI: 0.34–0.54).
  • Diabetic patients with malnutrition had significantly lower levels of body mass index, albumin, hemoglobin, triglyceride, and high-density lipoprotein cholesterol, while showing an increase in glycosylated hemoglobin.
  • C-reactive protein >10 mg/L, age, duration of diabetes, Wagner grades 3–5, with cardiovascular disease, and using insulin were identified as risk factors for malnutrition in diabetic patients.

ORIGINAL ARTICLE
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Comparing Glucagon‐like peptide‐1 receptor agonists versus metformin in drug‐naive patients: A nationwide cohort study

  •  4 October 2024

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Comparing Glucagon-like peptide-1 receptor agonists versus metformin in drug-naive patients: A nationwide cohort study Issue 10, 2024

Highlights

  • In this nationwide cohort study, initiating GLP-1 RA as the first-line treatment was associated with improved 1-year HbA1c levels compared with metformin.
  • GLP-1 RA initiation was also associated with a lower risk of requiring additional glucose-lowering therapy; however, initial treatment adherence varied depending on the prediabetes or diabetes status.
  • Overall, GLP-1 RAs as the first-line choice for 1-year outcomes may exhibit variability regarding treatment management based on prediabetes or diabetes status, but they generally result in improved glycemic control.

ORIGINAL ARTICLE
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Assessing and predicting type 2 diabetes risk with triglyceride glucose-body mass index in the Chinese nondiabetic population—Data from long-term follow-up of Da Qing IGT and Diabetes Study

  •  4 October 2024

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Assessing and predicting type 2 diabetes risk with triglyceride glucose-body mass index in the Chinese nondiabetic population—Data from long-term follow-up of Da Qing IGT and Diabetes Study Issue 10, 2024

Highlights

  • After the 34-year follow-up, increased TyG-BMI was independently associated with a higher risk of type 2 diabetes.
  • TyG-BMI exhibited higher predictive ability than TyG or HOMA-IR in both short (6-year) and long terms (34-year). The best thresholds of TyG-BMI to predict diabetes were relatively stable (195.24–208.41).
  • Our results provide the possibility to utilize TyG-BMI for predicting diabetes risk in clinical practice.

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Effectiveness of wearable technology‐based physical activity interventions for adults with type 2 diabetes mellitus: A systematic review and meta‐regression

  •  4 October 2024

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Effectiveness of wearable technology-based physical activity interventions for adults with type 2 diabetes mellitus: A systematic review and meta-regression Issue 10, 2024

Highlights

  • In people with diabetes mellitus, wearable technology-based physical activity interventions significantly increased daily steps and reduced systolic blood pressure.
  • Intervention had a goal-setting component among T2DM patients, which had a greater effect on lowering BMI than their counterparts.
  • In terms of BMI reduction, the year of publication was a significant covariate.

ORIGINAL ARTICLE
Open access

Glycated albumin levels are associated with adverse stroke outcomes in patients with acute ischemic stroke in China

  •  12 September 2024

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Glycated albumin levels are associated with adverse stroke outcomes in patients with acute ischemic stroke in China Issue 9, 2024

Highlights

  • Elevated GA levels in serum were associated with stroke adverse outcomes.
  • Adding GA into the conventional model resulted in slight improvements in predicting poor functional outcomes.
  • The association between GA and poor functional outcomes was more pronounced in nondiabetic patients.

ORIGINAL ARTICLE
Open access

Fasting blood glucose level and risk of all‐cause and cause‐specific mortality in peritoneal dialysis patients

  •  12 September 2024

Graphical Abstract

Fasting blood glucose level and risk of all-cause and cause-specific mortality in peritoneal dialysis patients Issue 9, 2024

Highlights

  • A clear association was observed between FBG levels and the risk of all-cause mortality in PD patients, indicating that FBG is a significant indicator for quantifying the risk of all-cause mortality in these patients.
  • Although a higher FBG level was significantly associated with an increased risk of cardiovascular-related death, there was no notable increase in the risk of death from cancer or infections as the FBG levels increased.

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