Edited by: Vijayasaradhi Setaluri
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Pigment Cell & Melanoma Research is a dermatology journal publishing up-to-date manuscripts on all aspects of pigment cells and melanoma. From cell and molecular biology, development, genetics, to diseases of pigment cells, everything is comprehensively covered.
We look for papers that provide insights into the causes and progression of melanoma, aiming to advance the field and find ways to prevent this type of skin cancer, with a focus on the process of metastasis and invasion, proliferation, senescence, apoptosis or gene regulation.
Articles
Myron Gordon Award Lecture 2023: Painting the neural crest: How studying pigment cells illuminates neural crest cell biology
-  27 November 2023
Risk factors for sentinel lymph node metastasis in Korean acral and non‐acral melanoma patients
-  27 November 2023
MitoCur‐1 induces ferroptosis to reverse vemurafenib resistance in melanoma through inhibition of USP14
-  20 November 2023
Graphical Abstract

Graphic abstract illustrates that MitoCur-1 induces melanoma cell death and sensitization of vem-resistant melanoma cell through two ways: (1) inhibition of mitochondrial TrxR2, generation of ROS, and induction of the ROS-dependent glycolytic metabolisms (Zheng et al., Journal of Agricultural and Food Chemistry, 70, 2022, 2898–2910); (2) meanwhile, by inhibiting the expression of USP14, MitoCur-1 repressed activity of GPX4. The depletion of anti-oxidative enzyme aggravates the accumulation of lipid ROS and ferrous iron, and then triggers ferroptosis leading to melanoma cell death and overcoming vem resistance in melanoma.
CD52 mRNA expression predicts prognosis and response to immune checkpoint blockade in melanoma
-  17 November 2023
Single-cell profiling of MC1R-inhibited melanocytes
-  16 November 2023
Research Highlights

Single-cell RNAseq of MC1R-inhibited melanocytes elucidates a set of differentially expressed genes with no previous ties to pigmentation or melanocyte biology. This list includes Tbx3 which we show binds to T- and E-boxes of candidate target genes, including those with known roles in pigmentation.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference
-  E1-E13
-  14 March 2012
Melanins and melanogenesis: from pigment cells to human health and technological applications
-  520-544
-  14 July 2015
Melanins and melanogenesis: methods, standards, protocols
-  616-633
-  25 May 2013
L‐tyrosine and L‐dihydroxyphenylalanine as hormone‐like regulators of melanocyte functions
-  14-27
-  11 August 2011
Genetically engineered multicistronic allele of Pmel yielding highly specific CreERT2-mediated recombination in the melanocyte lineage
- Pigment Cell & Melanoma Research
-  71-77
-  22 November 2022